Cyclophosphamide combined with Doxorubicin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 7/31/2005 50 Male 200 lb 1/6/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 12/21/2005 Female 131 lb 1/9/2006 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 1/6/2006 Female 1/10/2006 Other Health Professional United States
Primary
Secondary
Neutrophil Count Abnormal Other Serious 12/28/2005 Female 140 lb 1/12/2006 United States
Primary
Secondary
Unresponsive To Verbal Stimuli Other Serious 67 Male 1/17/2006 Consumer United States
Primary
Secondary
Respiratory Distress Hospitalization 12/12/2005 72 Male 1/12/2006 France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/12/2005 57 Male 151 lb 10/28/2005 Pharmacist United States
Primary
Secondary
Neuroendocrine Carcinoma Of The Skin Other Serious 8/1/2004 51 Female 1/25/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/31/2005 Female 127 lb 1/20/2006 United States
Primary
Secondary
Rhabdomyolysis Other Serious 12/27/2005 Female 125 lb 1/18/2006 United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 1/27/2006 Other Health Professional United States
Primary
Secondary
Rash Other Serious 7/7/2004 Male 1/31/2006 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/20/2005 Male 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/19/2006 68 Male 4/26/2006 Other Health Professional United States
Primary
Secondary
Pulmonary Hypertension Hospitalization 1/17/2006 48 Female 154 lb 4/26/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 10 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 16 Male 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Arrhythmia Other Serious 5/11/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 5/11/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 32 Female 6/2/2006 Physician United States
Primary
Secondary
Leukocytosis Hospitalization 67 Female 6/2/2006 Physician United States
Primary
Secondary
Pyrexia Other Serious 32 Female 6/5/2006 Physician United States
Primary
Secondary
Pneumonia Death 6/15/2006 Austria
Primary
Secondary
Hypokinesia Hospitalization 2/19/2006 59 Male 265 lb 6/12/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 5/30/2006 Male 6/14/2006 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 70 Female 239 lb 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 9 Female 7/6/2006 Other Health Professional United States
Primary
Secondary
Neutropenia Hospitalization 3/28/2005 52 Female 168 lb 7/14/2006 Physician Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/19/2006 56 Female Pharmacist United States
Primary
Secondary
Blood Alkaline Phosphatase Increased 4/12/2006 44 Female 7/25/2006 United Kingdom
Primary
Concomitant
Local Swelling Male 7/28/2006 United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/24/2006 Female 224 lb 8/1/2006 United States
Primary
Secondary
Vomiting Hospitalization 5/9/2006 64 Male 8/3/2006 Other Health Professional United States
Primary
Secondary
Refusal Of Treatment By Patient Hospitalization 58 Female 9/1/2006 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 9/3/2005 Female 151 lb 9/7/2006 Other Health Professional United States
Primary
Secondary
Leukoencephalopathy Other Serious 56 Male 9/21/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 8/4/2006 31 Female 148 lb 10/2/2006 Other Health Professional Venezuela
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 56 Male 10/3/2006 Other Health Professional United States
Primary
Secondary
Lung Infection Pseudomonal Other Serious 50 Female 9/29/2006 Canada
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 11/1/1998 43 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 62 Female 10/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2006 62 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/1999 54 Male 10/13/2006
Primary
Secondary
Sepsis Death 34 Male 10/17/2006 Physician United States
Primary
Concomitant
Sepsis Death 39 Male 10/17/2006 Physician United States
Primary
Concomitant
Pseudomonas Infection Death 67 Female 10/23/2006 Physician United States
Primary
Concomitant
Peritonitis Death 72 Male 10/23/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 52 Female 12/7/2006 Other Health Professional United States
Primary
Secondary
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 12/7/2006 Physician Australia
Primary
Secondary
Pain In Extremity Other Serious 11/1/1998 43 Male 12/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 11/1/1998 43 Male 12/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 12/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 21 Female 1/8/2007 Physician Turkey
Primary
Concomitant
Tachycardia Other Serious 9/28/2006 72 Female 141 lb 1/16/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 44 Female 4/13/2007 Physician Spain
Primary
Secondary
Septic Shock Other Serious 44 Female 4/18/2007 Physician Spain
Primary
Secondary
Tachycardia Other Serious 2/16/2005 17 Male 4/18/2007 Other Health Professional Malaysia
Primary
Secondary
Lymphoma Other Serious 62 Female 4/18/2007 Other Health Professional Japan
Primary
Secondary
Pneumonitis Other Serious 60 Male 4/18/2007 Other Health Professional Japan
Primary
Secondary
Myalgia Other Serious 1/10/2007 43 Female 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 2/28/2007 Female 4/19/2007 Physician United States
Primary
Concomitant
Leukopenia Hospitalization 3/1/2007 50 Female 144 lb 4/19/2007 Physician Philippines
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 30 4/19/2007 Norway
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 61 4/19/2007 Norway
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 47 4/19/2007 Norway
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 62 Female 5/5/2007 Physician Switzerland
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 2/11/2007 65 Male 157 lb 5/14/2007 Physician France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 44 Female 5/23/2007 Physician Spain
Primary
Secondary
Chest Pain Hospitalization 5/12/2007 Female 5/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 67 Male 5/25/2007 Physician United Kingdom
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 20 Female 5/25/2007 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 20 Female 5/25/2007 United States
Primary
Concomitant
Psychotic Disorder Hospitalization 11/25/2006 7/2/2007 Physician United Kingdom
Primary
Secondary
Metastasis Hospitalization 1/1/2002 67 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Paraparesis Life Threatening 1/1/2002 67 Female 7/20/2007 United Kingdom
Primary
Secondary
Platelet Count Decreased Life Threatening 69 Male 7/27/2007 Other Health Professional Turkey
Primary
Secondary
Tremor Life Threatening 7/5/2007 36 Female 119 lb 8/2/2007 Other Health Professional Portugal
Primary
Concomitant
Metastasis Hospitalization 1/1/2002 40 Female 8/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Rash Erythematous Hospitalization 43 Female 8/3/2007
Primary
Secondary
Lymphoma Other Serious 52 Male 8/8/2007 Physician Canada
Primary
Secondary
Pleocytosis Life Threatening 1/1/2002 40 Female 8/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Nausea Life Threatening 5/25/2007 Female 86 lb 8/10/2007 Germany
Primary
Concomitant
Lymphoma Other Serious 52 Male 8/10/2007 Physician United States
Primary
Secondary
Mental Disorder Due To A General Medical Condition Other Serious Female 357 lb 8/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious Female 115 lb 8/13/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 43 Female 8/13/2007 Australia
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/5/2007 Male 176 lb 8/14/2007 Physician Switzerland
Primary
Concomitant
Nodular Regenerative Hyperplasia Other Serious Female 8/11/2007 Physician Turkey
Primary
Secondary
Concomitant
Spinal Anaesthesia Life Threatening 1/1/2002 40 Male 8/10/2007 United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 43 Female 8/16/2007 Physician Australia
Primary
Secondary
White Blood Cell Count Increased Hospitalization 69 Female 8/16/2007
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 43 Female 8/17/2007 Physician Australia
Primary
Secondary
Aspergillosis Other Serious 1/1/2007 Male 8/16/2007 Physician Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 8/2/2007 73 Female 8/17/2007 United States
Primary
Secondary
Thymus Enlargement Other Serious 4 Male 8/15/2007 Physician Korea, Democratic People's Republic Of
Primary
Secondary
Tachycardia Hospitalization 1/21/2007 42 Female 8/13/2007 France
Primary
Secondary
Concomitant
Cardiopulmonary Failure Death 8/7/2007 75 Male 8/22/2007 Physician Israel
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/5/2001 Female 144 lb 8/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Demyelinating Polyneuropathy Hospitalization 4/3/2007 Female 99 lb 8/24/2007 Physician Japan
Primary
Concomitant
Brain Natriuretic Peptide Increased Other Serious Male 8/29/2007 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 7/20/2007 35 Male 143 lb 9/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 1/1/2002 71 Male 9/4/2007
Primary
Concomitant
Metastasis Hospitalization 1/1/2002 40 Female 9/7/2007 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Hospitalization 7/3/2007 53 Female 148 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Polyneuropathy Death 1/5/2007 Female 130 lb 9/10/2007 Consumer France
Primary
Secondary
Multiple Myeloma Hospitalization 55 Male 11/9/2007 Physician United States
Primary
Concomitant
Cytogenetic Abnormality Other Serious 47 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 54 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Haematopoietic Stem Cell Mobilisation Other Serious 56 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 48 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 47 Female 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Mass Hospitalization 2/4/2008 Physician Hong Kong
Primary
Secondary
Pulmonary Toxicity Other Serious 28 Female 1/29/2008 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 76 Male 2/6/2008 Other Health Professional Italy
Primary
Concomitant
Loss Of Consciousness Other Serious 6 Male 2/7/2008 Turkey
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 60 Male 2/4/2008 Physician Germany
Primary
Concomitant
Large Intestinal Haemorrhage Hospitalization Male 150 lb 2/8/2008 Consumer United Kingdom
Primary
Concomitant
Kaposi's Sarcoma Other Serious 10/1/2005 55 Male 2/8/2008 Physician United Kingdom
Primary
Secondary
Renal Failure Death 3/12/2008 74 Female 123 lb 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 6/20/2008 Female 7/24/2008 Physician United Kingdom
Primary
Secondary
Pancytopenia Other Serious 3/1/2007 62 Female 7/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Disorder Hospitalization 6/16/2008 7/28/2008 Physician Italy
Primary
Secondary
Tinnitus Hospitalization 46 Male 9/19/2008 Italy
Primary
Secondary
Vision Blurred Other Serious 8/24/2008 76 Female 11/25/2008 Other Health Professional Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/18/2008 Female 168 lb 12/9/2008 Physician United States
Primary
Secondary
Interstitial Lung Disease Hospitalization 56 Female 143 lb 12/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Sinusitis Other Serious 7/1/2008 61 Female 12/9/2008 Consumer United Kingdom
Primary
Concomitant
Anal Fistula Other Serious 10/1/2007 Female 12/10/2008 Consumer United Kingdom
Primary
Concomitant
Infection Life Threatening 3/6/2007 Female 134 lb 12/10/2008 United States
Primary
Concomitant
Lymphopenia Hospitalization 2/20/2007 Female 134 lb 12/11/2008 United States
Primary
Concomitant
Radiation Skin Injury Other Serious 5/1/2007 42 Female 12/11/2008 Physician United States
Primary
Concomitant
Lacrimation Increased Other Serious 10/18/2006 12/11/2008 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 72 Male 12/31/2008 Physician United Kingdom
Primary
Concomitant
Myelopathy Other Serious 11/1/2001 53 Male 1/16/2009 Germany
Primary
Concomitant
Facial Palsy Other Serious 1/27/2009 Other Health Professional Japan
Primary
Secondary
Splenic Rupture Other Serious 20 Male 1/29/2009 Other Health Professional Pakistan
Primary
Secondary
Interstitial Lung Disease Other Serious 70 Male 1/28/2009 Italy
Primary
Secondary
Acute Respiratory Failure Other Serious 64 Male 1/28/2009 Italy
Primary
Secondary
Diffuse Alveolar Damage Other Serious 20 Male 1/28/2009 Italy
Primary
Secondary
T-cell Lymphoma Hospitalization 11/30/2008 70 Male 1/29/2009 Physician Italy
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 9/9/2008 Female 1/30/2009 Physician Spain
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 12/28/2008 Male 2/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 9/5/2008 Male 2/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 72 Male 2/27/2009 Physician United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 72 Male 2/27/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Other Serious 4/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Pain Hospitalization 3/27/2009 84 Female 163 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/1/2009 75 Male 139 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data