Cyclophosphamide combined with Doxorubicin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 11/11/2004 76 Female 1/3/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/19/2005 25 Male 1/3/2006 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 53 Male 1/17/2006 Japan
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/13/2004 67 Female 117 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 3/17/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 2/13/2004 63 Male 4/14/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 75 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Hepatitis Toxic Hospitalization 2/24/2006 31 Male 5/8/2006 Physician France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/4/2006 40 Female 209 lb 5/8/2006 Physician France
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 4/7/2006 66 Female 5/8/2006 France
Primary
Secondary
White Blood Cell Count Abnormal Life Threatening 4/12/2006 Female 170 lb 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 2/7/2006 40 Female 209 lb 5/15/2006 Physician France
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 2/1/2006 52 Male 5/17/2006 Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/15/2005 Female 150 lb 2/24/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/1/2005 Female 2/24/2006 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/1/2005 Female 2/24/2006 United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 7/13/2005 62 Female 2/24/2006 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/19/2005 59 Female 155 lb 2/24/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/20/2005 Female 2/24/2006 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/11/2005 70 Female 177 lb 2/24/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/11/2005 70 Female 2/24/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 7/27/2005 74 Female 2/24/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 8/1/2005 70 Female 2/24/2006 United States
Primary
Concomitant
Renal Failure Chronic Death 3/16/2006 Male 5/24/2006 Physician Poland
Primary
Secondary
Therapy Non-responder Other Serious 4/1/2006 Male 165 lb 6/2/2006 Physician Spain
Primary
Concomitant
Thrombosis Other Serious 3/7/2006 Female 200 lb 3/23/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 2/14/2006 Female 152 lb 3/28/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/31/2006 Female 154 lb 3/28/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/17/2006 Female 155 lb 3/28/2006 United States
Primary
Secondary
Leukocytosis Hospitalization Female 6/7/2006 United States
Primary
Concomitant
Intestinal Perforation Other Serious 5/28/2006 Female 287 lb 5/31/2006 United States
Primary
Secondary
Febrile Neutropenia Other Serious 5/30/2006 Female 89 lb 6/5/2006 United States
Primary
Secondary
Liver Function Test Abnormal Other Serious 5/30/2006 Female 140 lb 6/5/2006 United States
Primary
Secondary
Skin Infection Hospitalization 4/1/2006 79 Male 6/13/2006 Other Health Professional Australia
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 Male 146 lb 6/13/2006 Physician Canada
Primary
Concomitant
Death Death 80 Male 6/13/2006 Physician Germany
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 2/1/2006 59 Male 265 lb 6/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 6/6/2006 Female 172 lb 6/8/2006 United States
Primary
Secondary
Concomitant
Sideroblastic Anaemia Other Serious 4/1/2006 Male 165 lb 6/19/2006 Physician Spain
Primary
Concomitant
Pneumonia Hospitalization 80 Male 6/20/2006 Physician Germany
Primary
Concomitant
Tumour Lysis Syndrome Death 3/16/2006 Male 6/13/2006 Physician Poland
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/21/2004 37 Male 6/15/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 5/30/2006 Female 140 lb 6/19/2006 United States
Primary
Secondary
Sideroblastic Anaemia Other Serious 4/1/2006 Male 165 lb 6/23/2006 Physician Spain
Primary
Concomitant
Pancytopenia Other Serious 2/14/2002 33 Male 130 lb 6/20/2006 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/12/2005 65 Male 6/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/14/2006 Male 170 lb 6/19/2006 United States
Primary
Secondary
Vomiting Hospitalization 6/21/2006 Female 170 lb 6/28/2006 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis 6/23/2006 Male 227 lb 6/26/2006 United States
Primary
Secondary
Hepatitis Toxic Hospitalization 2/24/2006 31 Male 6/27/2006 Physician France
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization Male 6/28/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/22/2006 7/5/2006 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/29/2006 Female 166 lb 6/29/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 6/22/2006 Female 7/11/2006 Consumer United States
Primary
Concomitant
Urosepsis Hospitalization 6/27/2006 Female 176 lb 7/13/2006 United States
Primary
Secondary
Intestinal Perforation Hospitalization 5/27/2006 Female 287 lb 7/11/2006 United States
Primary
Concomitant
Liver Disorder Hospitalization 5/30/2006 Female 140 lb 7/13/2006 United States
Primary
Secondary
Rash Pustular 5/21/2002 Female 122 lb 8/8/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Death 6/30/2005 79 Male 8/2/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/24/2006 Female 224 lb 8/7/2006 United States
Primary
Secondary
Mucosal Inflammation Hospitalization 7/31/2006 Male 168 lb 8/1/2006 United States
Primary
Secondary
Rectal Haemorrhage Hospitalization 7/30/2006 Female 178 lb 7/31/2006 United States
Primary
Secondary
White Blood Cell Count Decreased 8/7/2006 Female 219 lb 8/9/2006 United States
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 2/23/2006 Female 146 lb 8/15/2006 Physician United States
Primary
Concomitant
Swelling Hospitalization 60 8/9/2006 Other Health Professional Germany
Primary
Secondary
White Blood Cell Count Increased Hospitalization 7/18/2005 Female 200 lb 8/14/2006 United States
Primary
Secondary
Pulmonary Embolism Hospitalization 8/9/2006 Female 200 lb 8/15/2006 United States
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 2/23/2006 Female 146 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/22/2006 Male 223 lb 8/14/2006 United States
Primary
Secondary
Cardiac Failure Congestive Hospitalization 7/29/2006 Male 165 lb 8/21/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/7/2006 Female 222 lb 8/17/2006 United States
Primary
Secondary
Respiratory Failure Hospitalization 8/12/2006 Female 134 lb 8/17/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/21/2006 Female 223 lb 8/21/2006 United States
Primary
Secondary
Orthostatic Hypotension Hospitalization 7/22/2006 Male 223 lb 8/28/2006 United States
Primary
Secondary
Pneumonia Primary Atypical Hospitalization 8/18/2006 Female 123 lb 8/21/2006 United States
Primary
Secondary
Neutrophil Count Decreased 7/31/2006 Female 136 lb 8/28/2006 United States
Primary
Secondary
Neutrophil Count Decreased 8/21/2006 Female 136 lb 8/29/2006 United States
Primary
Secondary
Pulmonary Embolism Hospitalization 8/23/2006 Male 53 lb 8/24/2006 United States
Primary
Secondary
Haemoglobin Decreased 8/23/2006 Female 203 lb 8/29/2006 United States
Primary
Secondary
Pyrexia Hospitalization 8/29/2006 62 Female 147 lb 8/30/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/29/2006 62 Female 147 lb 8/30/2006 United States
Primary
Secondary
Thrombocytopenia Hospitalization 8/30/2006 Female 200 lb 9/5/2006 United States
Primary
Secondary
White Blood Cell Count Decreased 8/31/2006 Female 243 lb 9/8/2006 United States
Primary
Secondary
White Blood Cell Count Decreased 9/5/2006 Female 216 lb 9/7/2006 United States
Primary
Secondary
Leukoencephalopathy Other Serious 56 Male 9/11/2006 United States
Primary
Secondary
Throat Tightness Hospitalization Male 9/18/2006 Physician Germany
Primary
Concomitant
Septic Shock Life Threatening 8/29/2006 50 Male 9/18/2006 Physician Israel
Primary
Concomitant
Stomatitis Hospitalization 9/11/2006 Female 112 lb 9/11/2006 United States
Primary
Secondary
Concomitant
Rhinitis Hospitalization 4/3/2006 84 Female 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 9/5/2006 Female 136 lb 9/13/2006 United States
Primary
Secondary
Pericardial Effusion Hospitalization 7/27/2006 64 Unknown 9/19/2006 Other Health Professional Japan
Primary
Secondary
Urticaria Hospitalization 8/16/2006 Male 196 lb 10/3/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/16/2006 Female 108 lb 9/27/2006 United States
Primary
Secondary
Pancytopenia Death 46 Female 10/4/2006 Physician Spain
Primary
Secondary
White Blood Cell Count Decreased 10/2/2006 Female 218 lb 10/3/2006 United States
Primary
Secondary
White Blood Cell Count Decreased 9/18/2006 Female 225 lb 10/5/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/29/2006 Female 150 lb 10/6/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 8/1/2006 Female 292 lb 10/13/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/12/2006 Female 134 lb 10/11/2006 United States
Primary
Secondary
Urinary Tract Infection Hospitalization 2/23/2006 Female 146 lb 10/16/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/13/2006 Male 208 lb 10/16/2006 United States
Primary
Secondary
Pain Hospitalization 9/21/2006 Male 168 lb 10/11/2006 United States
Primary
Secondary
White Blood Cell Count Decreased 10/11/2006 Male 142 lb 10/19/2006 United States
Primary
Secondary
Neutropenia 10/13/2006 Female 277 lb 10/20/2006 United States
Primary
Secondary
Peritonitis Bacterial Hospitalization 10/18/2006 Male 195 lb 10/20/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 10/9/2006 Male 52 lb 10/20/2006 United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 9/13/2006 Female 156 lb 10/25/2006 United States
Primary
Secondary
White Blood Cell Count Decreased 9/27/2006 Female 155 lb 10/25/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/13/2006 Female 159 lb 10/26/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 10/11/2006 Female 155 lb 10/25/2006 United States
Primary
Secondary
Wound Secretion Other Serious 9/12/2006 32 Male 11/1/2006 Other Health Professional France
Primary
Secondary
Sepsis Hospitalization Female 87 lb 11/9/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/8/2006 Female 151 lb 11/15/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 8/1/2006 58 Female 11/22/2006 United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 56 Male 11/22/2006 Consumer United States
Primary
Secondary
Platelet Count Decreased Hospitalization 10/11/2006 Female 132 lb 11/14/2006 United States
Primary
Secondary
Neutrophil Count Decreased 11/9/2006 Female 229 lb 11/13/2006 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 11/28/2006 Other Health Professional Israel
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 11/28/2006 Other Health Professional Israel
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/9/2006 Male 52 lb 11/22/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/16/2006 Male 136 lb 11/17/2006 United States
Primary
Secondary
Venoocclusive Liver Disease Hospitalization 11/23/2006 Female 40 lb 11/27/2006 Other Health Professional United States
Primary
Secondary
Weight Increased Hospitalization 11/23/2006 Female 40 lb 11/30/2006 Other Health Professional United States
Primary
Secondary
Sinusitis 11/24/2006 Female 280 lb 12/4/2006 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 12/4/2006 Male 194 lb 12/5/2006 United States
Primary
Secondary
Tongue Disorder Hospitalization 11/28/2006 Female 167 lb 12/8/2006 United States
Primary
Secondary
Concomitant
Insomnia Hospitalization 11/16/2006 Female 127 lb 12/6/2006 United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 12/1/2006 Male 12/15/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Delayed Hospitalization 12/18/2006 Other Health Professional Israel
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2006 Female 87 lb 12/13/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 12/7/2006 Female 229 lb 12/8/2006 United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 47 Female 12/4/2006 Other Health Professional United States
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Other Serious 55 Female 12/4/2006 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 12/10/2006 Female 100 lb 12/13/2006 United States
Primary
Secondary
Therapeutic Response Decreased Hospitalization Female 12/20/2006 Other Health Professional United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization Female 12/11/2006 United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 12/3/2006 Female 147 lb 12/15/2006 United States
Primary
Secondary
Vomiting Hospitalization 11/23/2006 Female 40 lb 12/18/2006 United States
Primary
Secondary
Pharyngitis Hospitalization 12/12/2006 Female 166 lb 12/21/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/20/2006 Female 173 lb 12/22/2006 United States
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 1/1/2000 60 Female 1/9/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/27/2006 Female 164 lb 1/2/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 12/27/2006 Female 243 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Pericarditis Hospitalization 12/1/2006 56 Male 1/12/2007 Other Health Professional Switzerland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/11/2007 Female 177 lb 1/12/2007 United States
Primary
Secondary
No Therapeutic Response Hospitalization 11/13/2006 Female 132 lb 1/18/2007 Physician Portugal
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/27/2006 Female 243 lb 1/17/2007 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/20/2006 Female 173 lb 1/9/2007 United States
Primary
Secondary

Drug Data