Cyclophosphamide combined with Doxorubicin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 56 Male 10/27/2005 Physician United States
Primary
Secondary
Concomitant
Anaphylactic Shock Other Serious 10/25/2005 39 Female 1/2/2006 Physician France
Primary
Secondary
Neutropenia Other Serious 70 Female 1/2/2006 Other Health Professional Australia
Primary
Concomitant
Sudden Death Death 58 Female 123 lb 1/2/2006 Physician Poland
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 12/21/2005 Female 42 lb 12/27/2005 United States
Primary
Secondary
Thrombocytopenia Hospitalization 12/9/2003 51 Male 12/30/2005 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2006 Female 215 lb 1/4/2006 United States
Primary
Secondary
Vomiting Other Serious 12/28/2005 Male 166 lb 1/5/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/7/2004 62 Male 1/5/2006 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 9/1/2005 63 Female 196 lb 1/5/2006 Physician Germany
Primary
Concomitant
Stomatitis Required Intervention 12/30/2005 Female 156 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 12/31/2005 Female 99 lb 1/6/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/18/2001 53 Male 95 lb 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatitis B Hospitalization 12/1/2005 Female 198 lb 12/30/2005 United States
Primary
Secondary
Pseudomonas Infection Other Serious 12/20/2005 Male 153 lb 1/9/2006 United States
Primary
Secondary
Therapy Non-responder Hospitalization 12/31/2005 Female 127 lb 1/6/2006 United States
Primary
Secondary
Stomatitis Hospitalization 12/30/2005 Female 156 lb 1/11/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/11/2006 Male 154 lb 1/12/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/8/2006 Female 215 lb 1/11/2006 United States
Primary
Secondary
Thrombocytopenia Other Serious 1/9/2006 Female 145 lb 1/11/2006 United States
Primary
Secondary
Hyperglycaemia Required Intervention 1/9/2006 Female 208 lb 1/10/2006 United States
Primary
Secondary
Concomitant
Sudden Death Death 58 Female 123 lb 1/13/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 72 Male 1/13/2006 Japan
Primary
Secondary
Polymyositis Other Serious 54 Female 156 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/21/2005 Female 138 lb 1/17/2006 United States
Primary
Secondary
Concomitant
Sudden Death Death 8/9/2005 58 Female 123 lb 1/19/2006 Physician Poland
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/14/2006 Female 177 lb 1/17/2006 United States
Primary
Secondary
Stomatitis Other Serious 12/6/2005 Female 152 lb 1/19/2006 United States
Primary
Secondary
Premature Baby Hospitalization 4/22/2004 Male 5 lb 1/20/2006 Australia
Primary
Secondary
Concomitant
Pain Hospitalization Female 1/26/2006 Physician Germany
Primary
Concomitant
Tachypnoea Hospitalization 12/25/2005 Female 198 lb 1/23/2006 United States
Primary
Secondary
Unresponsive To Verbal Stimuli Required Intervention 1/22/2006 Male 181 lb 1/23/2006 United States
Primary
Secondary
Unresponsive To Verbal Stimuli Other Serious 1/22/2006 Male 181 lb 1/26/2006 United States
Primary
Secondary
Tachycardia Other Serious 7/21/2005 31 lb 1/17/2006 United States
Primary
Secondary
Premature Labour Hospitalization 4/22/2004 Female 1/23/2006 Australia
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 7/21/2004 82 Male 1/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 37 Female 1/24/2006 Physician United States
Primary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 6/21/2004 82 Male 1/24/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Deafness Unilateral Hospitalization 12/2/2005 57 Female 1/24/2006 Physician France
Primary
Secondary
Vomiting Other Serious 1/19/2006 Female 125 lb 1/26/2006 United States
Primary
Secondary
Leukopenia Other Serious 33 Female 1/27/2006 Physician Taiwan, Province Of China
Primary
Secondary
Peripheral Motor Neuropathy Other Serious 1/4/2006 5 Female 35 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/13/2005 Female 172 lb 1/31/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/27/2005 Female 165 lb 1/31/2006 United States
Primary
Secondary
Hepatic Failure Death 12/5/2003 61 Male 2/1/2006 Physician Japan
Primary
Concomitant
Myalgia Hospitalization 1/4/2006 Female 2/7/2006 Physician Germany
Primary
Concomitant
Somnolence Other Serious 12/15/2005 65 Female 2/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/15/2005 65 Female 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 64 Female 2/3/2006 Physician France
Primary
Concomitant
Agranulocytosis Other Serious Unknown 2/6/2006 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 1/12/2006 64 Female 148 lb 2/3/2006 France
Primary
Secondary
White Blood Cell Count Decreased Death 9/18/2005 60 Male 2/3/2006 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 12/29/2005 53 Male Pharmacist United States
Primary
Secondary
Vomiting Other Serious 1/11/2006 Male 154 lb 2/6/2006 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/9/2005 79 Male Pharmacist United States
Primary
Secondary
Constipation Other Serious 12/6/2005 Male 156 lb 2/7/2006 United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 7/21/2005 Female 31 lb 2/2/2006 United States
Primary
Secondary
Shift To The Left Other Serious 1/23/2006 68 Male 198 lb 2/8/2006 Physician Australia
Primary
Concomitant
Vomiting Other Serious 1/11/2006 Male 154 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Other Serious 12/5/2005 Male 156 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/2/2006 Female 266 lb 2/9/2006 United States
Primary
Secondary
Concomitant
Hepatitis B Hospitalization 12/1/2005 Female 198 lb 2/10/2006 United States
Primary
Secondary
Syncope Hospitalization 2/12/2006 63 Male 229 lb 2/15/2006 Other Health Professional United States
Primary
Secondary
Hepatitis Other Serious 10/25/2005 56 Male 2/10/2006 Sweden
Primary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 7/21/2004 82 Male 2/10/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Troponin T Increased Other Serious 1/17/2005 Female 125 lb 2/13/2006 United States
Primary
Secondary
Vomiting Other Serious 2/2/2006 Male 143 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 52 Male 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/26/2006 58 Female 2/13/2006 Physician Australia
Primary
Secondary
Pulmonary Embolism Required Intervention 1/29/2006 Female 161 lb 2/6/2006 United States
Primary
Secondary
Pharyngolaryngeal Pain Other Serious 2/15/2006 Female 201 lb 2/16/2006 United States
Primary
Secondary
Vomiting Required Intervention 2/10/2006 Female 180 lb 2/17/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/6/2006 Female 140 lb 2/15/2006 United States
Primary
Secondary
Neutropenia Other Serious 1/21/2005 53 Male 2/16/2006 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 9/27/2005 66 Female 2/16/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/7/2004 67 Female 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/15/2005 64 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 73 Female 2/17/2006 Physician France
Primary
Concomitant
Rhabdomyoma Other Serious 73 Male 2/24/2006 Consumer United States
Primary
Secondary
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/23/2006 59 Male 187 lb 2/17/2006 Australia
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/27/2005 67 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 2/21/2006 Physician Spain
Primary
Secondary
Weight Decreased Other Serious 2/3/2005 Female 183 lb 2/16/2006 United States
Primary
Secondary
Pulmonary Embolism Other Serious 2/17/2006 Female 179 lb 2/20/2006 United States
Primary
Secondary
Concomitant
Transplant Life Threatening 7/2/2005 59 Male 139 lb 2/22/2006 Physician France
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/22/2006 Physician France
Primary
Secondary
Concomitant
Papillary Muscle Rupture Hospitalization 1/17/2006 48 Female 154 lb 2/22/2006 Physician Germany
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 12/1/2005 42 Female 2/22/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/2/2006 Male 143 lb 2/21/2006 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 11/5/2005 40 Female 154 lb 2/24/2006 France
Primary
Secondary
Cerebral Haemorrhage Death 2/24/2006 Physician Spain
Primary
Secondary
Pain Hospitalization Female 3/3/2006 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 67 Female 2/27/2006 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 24 Male 165 lb 3/6/2006 Physician Norway
Primary
Concomitant
Pneumoperitoneum Other Serious 2/1/2006 Male 157 lb 2/28/2006 United States
Primary
Secondary
Gastrointestinal Toxicity Other Serious 11/28/2005 Female 172 lb 2/21/2006 United States
Primary
Secondary
Thrombocytopenia Other Serious 2/12/2006 Female 119 lb 2/27/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia 27 Male 1/23/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 2/1/1999 41 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Wrong Drug Administered Death 8/26/2005 21 Male 3/1/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Death Male 3/2/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 9/10/2004 71 Female 117 lb 3/1/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 8/11/2003 Female 169 lb 3/3/2006 United States
Primary
Secondary
Prostration Hospitalization 12/1/2005 Male 168 lb 3/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Liver Disorder Other Serious 3/1/2006 Physician Japan
Primary
Concomitant
Therapy Non-responder Hospitalization 2/11/2006 Female 179 lb 3/3/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/17/2005 64 Male 119 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/26/2005 57 Male 101 lb 3/10/2006 Consumer United States
Primary
Secondary
Concomitant
Peritoneal Carcinoma Life Threatening 7/2/2005 59 Male 139 lb 3/6/2006 Physician France
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/26/2005 57 Male 101 lb 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Local Swelling Other Serious Male 3/7/2006 United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/23/2006 Female 227 lb 3/7/2006 United States
Primary
Secondary
Hyperbilirubinaemia Other Serious 3/3/2006 Male 189 lb 3/3/2006 United States
Primary
Secondary
Tumour Haemorrhage Death Female 22 lb 3/8/2006 United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 60 Female 3/7/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/2004 68 Male 152 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/4/2004 74 Female 115 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 48 Female 3/7/2006 United States
Primary
Concomitant
Skin Ulcer Other Serious 69 Female 3/7/2006 United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Female 3/7/2006 United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 11/1/2005 58 Female 3/8/2006 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 2/22/2006 Male 137 lb 3/9/2006 United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 46 Female 3/7/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 47 Female 3/7/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Hospitalization 12/15/2005 61 Male 3/15/2006 Consumer Netherlands
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious Female 3/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 2/14/2006 Female 23 lb 3/7/2006 United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 60 Male 3/13/2006 Physician France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/13/2005 75 Male 3/10/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 24 Male 165 lb 3/21/2006 Physician Norway
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 12/1/2005 75 Female 176 lb 3/15/2006 Physician France
Primary
Concomitant
Skin Exfoliation Hospitalization 12/15/2005 61 Male 3/15/2006 Physician Netherlands
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 12/9/2005 71 Male 3/9/2006 France
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/1/2006 52 Male 203 lb 3/17/2006 Physician Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/6/2004 57 Male 3/17/2006 Physician Japan
Primary
Concomitant
Hepatotoxicity Other Serious 3/13/2006 Female 197 lb 3/20/2006 United States
Primary
Secondary
Concomitant
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 139 lb 3/16/2006 Physician France
Primary
Secondary
Concomitant
Dehydration Other Serious 3/21/2006 Male 152 lb 3/22/2006 United States
Primary
Secondary
Pyrexia Hospitalization 71 Male 3/20/2006 Physician France
Primary
Concomitant
Pyrexia Hospitalization 11/1/2005 Male 3/27/2006 Consumer
Primary
Concomitant
Visual Disturbance 10/27/2005 28 Female 119 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Subileus Required Intervention 7/19/2005 59 Female 3/22/2006 Physician Portugal
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 8/27/2005 63 Female 3/22/2006 Physician France
Primary
Secondary
Concomitant
Sepsis Death 55 Female 3/22/2006 Physician Korea, Democratic People's Republic Of
Primary
Secondary

Drug Data