Cyclophosphamide combined with Doxil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Other Serious 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/24/2006 Male 192 lb 2/16/2006 United States
Primary
Secondary
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/20/2006 70 Female 117 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/7/2006 70 Female 5/12/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 6/26/2006 Physician France
Primary
Secondary
White Blood Cell Count Increased Required Intervention 3/1/2005 73 Male 6/26/2006 Physician United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 7/13/2006 Physician France
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 7/28/2006 Physician France
Primary
Secondary
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Escherichia Infection Hospitalization 10/2/2006 56 Female 115 lb 10/13/2006 Physician France
Primary
Secondary
Malignant Neoplasm Progression Hospitalization 10/2/2006 56 Female 115 lb 10/23/2006 Physician France
Primary
Secondary
Aortic Thrombosis Hospitalization 10/12/2006 74 Male 156 lb 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/2/2006 56 Female 115 lb 10/26/2006 Physician France
Primary
Secondary
Pituitary Tumour Benign Life Threatening 6/30/2006 61 Male 190 lb 11/8/2006 Physician France
Primary
Secondary
Central Pontine Myelinolysis Hospitalization 70 Female 12/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Spinal Compression Fracture Other Serious 11/1/1998 43 Male 12/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 12/28/2006 Physician France
Primary
Secondary
Helicobacter Infection Hospitalization 11/4/2006 Female 1/30/2007 Physician United States
Primary
Secondary
Osteoporosis Other Serious 11/1/1998 43 Male 3/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/1998 43 Male 3/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 3/13/2007 Female 118 lb 3/20/2007 United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 3/29/2007 Male 176 lb 4/2/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/27/2007 Male 227 lb 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia 4/2/2007 Female 124 lb 4/19/2007 United States
Primary
Secondary
Concomitant
Infection Hospitalization 1/27/2007 Male 227 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/8/2007 Male 147 lb 5/9/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 5/11/2007 Physician France
Primary
Secondary
Pyrexia Hospitalization 5/8/2007 Male 147 lb 5/18/2007 United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 5/16/2007 Male 168 lb 5/18/2007 United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 5/16/2007 Male 168 lb 5/31/2007 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/23/2007 Male 241 lb 5/30/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/23/2007 Male 241 lb 6/5/2007 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 4/30/2007 Female 129 lb 6/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/14/2007 Female 138 lb 6/15/2007 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/27/2007 Male 156 lb 7/2/2007 United States
Primary
Secondary
Respiratory Failure Hospitalization 7/10/2007 Male 155 lb 7/16/2007 United States
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 7/19/2007 Male 150 lb 7/25/2007 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 7/10/2007 Male 155 lb 7/26/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/14/2007 Female 89 lb 8/7/2007 United States
Primary
Secondary
Neutropenia 6/27/2007 Female 198 lb 8/8/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/20/2007 Male 194 lb 8/24/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 8/22/2007 Physician France
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/9/2007 Female 129 lb 9/14/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/23/2007 Female 125 lb 9/26/2007 United States
Primary
Secondary
Concomitant
Swelling Hospitalization 9/24/2007 Female 92 lb 9/27/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/30/2007 Male 157 lb 10/1/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 9/9/2007 Female 129 lb 10/1/2007 United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/7/2007 Male 232 lb 10/12/2007 United States
Primary
Secondary
Pyrexia Hospitalization 9/30/2007 Male 157 lb 10/31/2007 United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 11/1/2007 Female 95 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/30/2007 Male 157 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 11/1/2007 Female 95 lb 11/8/2007 United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 10/7/2007 Male 232 lb 11/6/2007 United States
Primary
Secondary
Status Epilepticus Hospitalization 11/1/2007 Female 95 lb 11/13/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/30/2007 Male 157 lb 11/14/2007 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/1/2007 Female 95 lb 11/14/2007 United States
Primary
Secondary
Concomitant
Treatment Failure Hospitalization 5/19/2006 59 Male 65 lb 12/5/2007 Physician France
Primary
Secondary
Neutropenia 12/10/2007 Male 189 lb 12/11/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/1/2008 Female 132 lb 2/5/2008 United States
Primary
Secondary
Pyrexia Hospitalization 2/19/2008 Male 299 lb 2/20/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/19/2008 Male 299 lb 2/25/2008 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 2/19/2008 Male 299 lb 2/27/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/14/2008 Female 123 lb 3/17/2008 United States
Primary
Secondary
Rectal Haemorrhage Hospitalization 3/4/2008 Male 148 lb 3/19/2008 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 3/29/2008 Female 180 lb 4/4/2008 United States
Primary
Secondary
Concomitant
Venous Thrombosis Limb Hospitalization 3/29/2008 Female 180 lb 4/9/2008 United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 3/29/2008 Female 180 lb 4/15/2008 United States
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 3/29/2008 Female 180 lb United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 4/24/2008 Male 183 lb 4/28/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/25/2008 Male 200 lb 5/5/2008 United States
Primary
Secondary
Concomitant
Treatment Failure Life Threatening 7/17/2006 61 Male 183 lb 5/6/2008 Physician France
Primary
Secondary
Thrombophlebitis Hospitalization 5/23/2008 Female 164 lb 5/30/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 6/6/2008 Male 194 lb 6/12/2008 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/4/2008 Female 190 lb 6/10/2008 United States
Primary
Secondary
Concomitant
Spinal Disorder Hospitalization 6/13/2008 Female 154 lb 6/18/2008 United States
Primary
Secondary
Concomitant
Neutropenia 6/4/2008 Female 190 lb 6/20/2008 United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 6/18/2008 Female 199 lb 7/10/2008 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 7/19/2008 Male 143 lb 7/22/2008 United States
Primary
Secondary
Abdominal Abscess Life Threatening 7/19/2008 50 Male 143 lb 7/29/2008 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 7/14/2008 Male 143 lb 7/24/2008 United States
Primary
Secondary
Tachycardia Hospitalization 8/1/2008 Male 221 lb 8/7/2008 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/9/2008 Male 212 lb 8/11/2008 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 8/14/2008 Male 159 lb 8/18/2008 United States
Primary
Secondary
Thrombocytopenia Life Threatening 8/14/2008 47 Male 159 lb 8/26/2008 Other Health Professional United States
Primary
Secondary
Abdominal Abscess Life Threatening 7/19/2008 45 Male 143 lb 9/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/31/2008 Male 163 lb 9/3/2008 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 8/9/2008 Male 212 lb 9/18/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2008 Female 200 lb 10/8/2008 Consumer United States
Primary
Concomitant
Splenic Vein Thrombosis 10/2/2008 57 Female 159 lb 10/7/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2008 Female 200 lb 10/10/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 9/22/2008 Male 146 lb 10/3/2008 United States
Primary
Secondary
Ventricular Arrhythmia Other Serious 6/18/2008 62 Female 199 lb 10/17/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 9/26/2008 Male 139 lb 10/22/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/29/2008 Female 170 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Syncope 12/17/2008 Male 165 lb 12/19/2008 United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/7/2009 Female 167 lb 1/8/2009 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/7/2009 Female 167 lb 1/12/2009 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 1/7/2009 Female 167 lb 1/20/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/30/2009 Female 169 lb 2/3/2009 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/29/2009 Female 180 lb 2/3/2009 United States
Primary
Secondary
Neutropenia 1/27/2009 Female 165 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 6/12/2008 Male 215 lb 3/4/2009 United States
Primary
Secondary
Pyrexia Hospitalization 9/2/2008 Male 132 lb 3/4/2009 United States
Primary
Secondary
Sepsis Syndrome Hospitalization 9/26/2008 Male 137 lb 3/4/2009 United States
Primary
Secondary
Steroid Withdrawal Syndrome Hospitalization 10/19/2008 Male 137 lb 3/4/2009 United States
Primary
Secondary
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia 2/23/2009 Male 169 lb 3/20/2009 United States
Primary
Secondary
Concomitant
Neutropenia 3/23/2009 Female 167 lb 3/31/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/1/2009 Female 108 lb 4/2/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/7/2009 Male 179 lb 4/10/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/8/2009 Female 268 lb 4/9/2009 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 4/15/2009 Female 172 lb 4/21/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/15/2009 Male 153 lb 4/17/2009 United States
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 4/21/2009 Female 110 lb 4/24/2009 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/15/2009 Female 172 lb 5/1/2009 United States
Primary
Secondary
Concomitant
Neck Pain Hospitalization 5/2/2009 Male 155 lb 5/7/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/13/2009 Male 168 lb 5/15/2009 United States
Primary
Secondary
Concomitant
Neck Pain Hospitalization 5/2/2009 Male 155 lb 5/21/2009 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/8/2009 Female 268 lb 5/27/2009 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/29/2009 Male 215 lb 6/1/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/15/2009 Female 168 lb 5/29/2009 United States
Primary
Secondary
Neutropenia 9/6/2007 Male 161 lb 6/5/2009 United States
Primary
Secondary
Weight Decreased Hospitalization 7/21/2007 Male 97 lb 6/2/2009 United States
Primary
Secondary
Palpitations Hospitalization 5/27/2008 Male 148 lb 6/8/2009 United States
Primary
Secondary
Vomiting Hospitalization 7/10/2007 Male 99 lb 6/2/2009 United States
Primary
Secondary
Small Intestinal Obstruction Hospitalization 6/13/2008 Male 183 lb 6/4/2009 United States
Primary
Secondary
Respiratory Failure Other Serious 10/1/2007 Female 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Abnormal Hospitalization 8/14/2008 Male 159 lb 6/24/2009 United States
Primary
Secondary
Pyrexia Hospitalization 8/31/2008 Male 163 lb 6/24/2009 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 6/27/2009 Male 155 lb 6/29/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/18/2009 Male 197 lb 7/21/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/19/2009 Male 156 lb 7/22/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 12/14/2007 Male 143 lb 7/13/2009 United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 12/4/2008 Male 136 lb 7/14/2009 United States
Primary
Secondary
Leukopenia 4/15/2008 Female 351 lb 7/13/2009 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 7/24/2009 50 Male 160 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/18/2009 Male 197 lb 7/29/2009 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/7/2009 Male 21 lb 7/29/2009 United States
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 7/19/2009 78 Male 156 lb 8/3/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/28/2009 Male 279 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased 8/5/2009 Male 218 lb 8/7/2009 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 7/19/2009 Male 156 lb 8/7/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/18/2009 Male 197 lb 8/6/2009 United States
Primary
Secondary
Concomitant
Atrial Fibrillation 7/31/2009 Male 192 lb 8/11/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/28/2009 Male 279 lb 8/11/2009 United States
Primary
Secondary
Concomitant

Drug Data