Cyclophosphamide combined with Daunorubicin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Other Serious 12/31/2005 Male 168 lb 1/5/2006 United States
Primary
Secondary
Respiratory Disorder Other Serious 17 Male 2/2/2006 Other Health Professional Ireland
Primary
Secondary
Pseudobulbar Palsy Other Serious 17 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Vomiting Other Serious 4/12/2006 Female 210 lb 4/19/2006 United States
Primary
Secondary
Febrile Neutropenia Other Serious 4/11/2006 Male 190 lb 4/20/2006 United States
Primary
Secondary
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 10 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 16 Male 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/5/2007 Female 132 lb 5/8/2007 United States
Primary
Secondary
Precocious Puberty Other Serious Female 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Shock Hospitalization Male 154 lb 9/28/2007 Poland
Primary
Concomitant
Renal Impairment Life Threatening 9/27/2007 Male 187 lb 10/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 65 Female 11/26/2007 Other Health Professional United States
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Pancytopenia Hospitalization 12/21/2007 Female 7/23/2008 Physician Australia
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/25/2008 United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 0 Male 11/20/2008 United States
Primary
Concomitant
Pyrexia Other Serious 0 Male 11/20/2008 Physician United States
Primary
Concomitant
Skin Disorder Other Serious 0 Female 11/20/2008 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/13/2008 Female 12 lb 11/25/2008 United States
Primary
Secondary
Pyrexia Hospitalization 12/6/2008 Female 18 lb 12/8/2008 United States
Primary
Secondary
Concomitant
Salivary Gland Cancer Other Serious 5 Male 3/20/2009 Other Health Professional Korea, Republic Of
Primary
Secondary
Skin Lesion Other Serious 5 Male 3/20/2009 Consumer Korea, Republic Of
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 5 Male 3/24/2009 Consumer Japan
Primary
Secondary
Skin Ulcer Hospitalization 11/11/2008 1 Male 24 lb 3/24/2009 Physician
Primary
Secondary
Concomitant
Hepatic Steatosis Hospitalization 3/20/2009 35 Female 128 lb 6/22/2009 Other Health Professional France
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 2 Female 11/24/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/7/2009 17 Male 146 lb 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2010 Male 130 lb 3/9/2010 Physician France
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 5/1/2008 27 Male 11/30/2010
Primary
Secondary
Pancreatitis Hospitalization 10/29/2010 12 Female 112 lb 11/29/2010 United States
Primary
Secondary
Diabetes Mellitus Hospitalization 8/1/2008 30 Female 12/9/2010 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome 11/10/2010 53 Female 159 lb 12/2/2010 United States
Primary
Secondary
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Life Threatening 7 Female 12/22/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 5 Female 2/17/2011 Other Health Professional Spain
Primary
Concomitant
Neurotoxicity Hospitalization 5 Female 2/17/2011 Other Health Professional Spain
Primary
Concomitant
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 5 Female 2/23/2011 Other Health Professional Spain
Primary
Secondary
Hepatic Steatosis Hospitalization 5/28/2010 16 Male 227 lb 2/15/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/22/2010 13 Female 98 lb 2/15/2011 Physician United States
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 8/1/2008 30 Female 176 lb 3/24/2011 Consumer United Kingdom
Primary
Secondary
Haemoglobin Decreased Other Serious 1/20/2011 60 Female 134 lb 4/5/2011 Physician United Kingdom
Primary
Secondary
Cardiotoxicity Other Serious 17 Female 4/7/2011 Other Health Professional Germany
Primary
Secondary
Subclavian Vein Thrombosis Hospitalization 7 Female 3/31/2011 Physician Germany
Primary
Concomitant
Myelopathy Other Serious 31 Female 7/18/2011 Other Health Professional Switzerland
Primary
Concomitant
Leukoencephalopathy Other Serious 10/26/2011 9 Female 12/14/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Cholestasis Hospitalization 9/1/2010 59 Female 1/23/2012 Other Health Professional France
Primary
Concomitant
Drug Interaction Other Serious 11 Female 6/13/2012 France
Primary
Concomitant
Interacting
Ileus Paralytic Other Serious 11 Female 2/7/2013 Country Not Specified
Primary
Concomitant
Interacting
Staphylococcal Infection Hospitalization 4/23/2012 4 Female 11/19/2012 Physician Us
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5 Male 9/14/2012 Other Health Professional Us
Primary
Secondary
Renal Failure Acute Hospitalization 5/31/2012 51 Female 2/22/2013 Other Health Professional Us
Primary
Secondary
Papillary Thyroid Cancer Other Serious 2/6/2012 43 Female 126 lb 12/27/2012 Physician Fr
Primary
Concomitant
Visual Acuity Reduced Other Serious 28 Female 8/28/2012 Other Health Professional Jp
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/2012 52 Female 9/5/2012 Registered Nurse Us
Primary
Secondary
Posterior Reversible Encephalopathy Syndrome Other Serious 2010 28 Female 9/12/2012 Jp
Primary
Secondary
Stomatitis Hospitalization 8/10/2012 10 Male 10/28/2013 Physician Us
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/10/2012 11 Male 1/18/2013 Physician Us
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/10/2012 11 Male 2/4/2013 Physician Us
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Hospitalization 8/6/2012 24 Female 9/26/2012 Consumer Us
Primary
Secondary
Concomitant
Central Nervous System Lesion Other Serious 25 Female 10/15/2012 Physician Nl
Primary
Concomitant
Respiratory Failure 6/8/2011 Female 155 lb 9/21/2012 Other Health Professional Us
Primary
Secondary
Multi-organ Failure Death 2012 Female 171 lb 11/12/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Skin Infection Hospitalization 2012 10 Female 99 lb 12/20/2012 Consumer Us
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Hospitalization 8/2012 24 Female 9/28/2012 Consumer Us
Primary
Secondary
Febrile Neutropenia Hospitalization 9/19/2012 1 Male 18 lb 10/3/2012 Physician Us
Primary
Secondary
Transaminases Increased Other Serious 6/7/2012 20 Male 254 lb 10/9/2012 Consumer Us
Primary
Secondary
Stomatitis Life Threatening 2012 Female 126 lb 10/9/2012 Consumer Us
Primary
Secondary
Urinary Tract Infection Enterococcal Life Threatening 7/27/2012 13 Female 271 lb 11/9/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Trendelenburg's Symptom Other Serious 12 Female 4/18/2013 Other Health Professional Us
Primary
Secondary
Osteonecrosis Other Serious 12 Female 10/15/2012 Physician Us
Primary
Secondary
Skin Infection Life Threatening 2012 17 Female 100 lb 10/22/2012 Consumer Us
Primary
Secondary
Coagulopathy Life Threatening 10/10/2009 13 Male 99 lb 10/24/2012 Physician Us
Primary
Secondary
Concomitant
Septic Shock Other Serious 10/1/2012 57 Female 231 lb 1/28/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2012 51 Female 2/20/2013 Consumer Us
Primary
Secondary
Concomitant
Trendelenburg's Symptom Required Intervention 12 Female 10/18/2012 Other Health Professional Us
Primary
Secondary
Sepsis Death 11/13/2012 Physician Sg
Primary
Secondary
Off Label Use Life Threatening 9/21/2012 2 Male 23 lb 11/20/2012 Consumer De
Primary
Secondary
Off Label Use Other Serious 9/21/2012 2 Male 23 lb 8/16/2013 Other Health Professional De
Primary
Secondary
Pneumothorax Death 11/13/2012 Physician Sg
Primary
Secondary
Toxic Dilatation Of Intestine Other Serious 6 Male 11/13/2012 Other Health Professional In
Primary
Secondary
Thrombocytopenia Hospitalization 7 Male 11/1/2012 Other Health Professional In
Primary
Secondary
Vascular Neoplasm Life Threatening 8/6/2012 12 Female Other Health Professional Us
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 8/7/2012 57 Male 227 lb 12/17/2012 Physician Fr
Primary
Secondary
Sepsis Hospitalization 11/22/2012 0 Male 16 lb 12/3/2012 Physician Us
Primary
Secondary
Venoocclusive Liver Disease Death 9 Male 88 lb 12/5/2012 Other Health Professional Jp
Primary
Secondary
Osteonecrosis Other Serious 12 Female 11/27/2012 Us
Primary
Secondary
Venoocclusive Liver Disease Death 9 Male 88 lb 12/12/2012 Other Health Professional Jp
Primary
Secondary
Venoocclusive Liver Disease Death 9 Male 88 lb 12/20/2012 Other Health Professional Jp
Primary
Secondary
Weight Increased Hospitalization 9 Male 88 lb 12/14/2012 Other Health Professional Jp
Primary
Secondary
Venoocclusive Liver Disease Death 6/27/2012 9 Male 12/20/2012 Jp
Primary
Secondary
Transaminases Increased Hospitalization 9/12/2012 38 Female 97 lb 4/18/2013 Consumer Jp
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 35 Female 3/18/2013 Physician Jp
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 52 Female 9/11/2012 Other Health Professional Us
Primary
Secondary
Off Label Use Death NotSpecified 3/26/2013 Other Health Professional Gb
Primary
Secondary
Pancreatitis Death NotSpecified 3/20/2013 Other Health Professional Gb
Primary
Secondary
Death Death NotSpecified 3/20/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Death NotSpecified 3/20/2013 Other Health Professional Gb
Primary
Secondary
Thrombosis Death NotSpecified 3/20/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Death NotSpecified 3/20/2013 Other Health Professional Gb
Primary
Secondary
Venoocclusive Disease Death NotSpecified 3/21/2013 Other Health Professional Gb
Primary
Secondary
Viral Infection Other Serious NotSpecified 3/29/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Other Health Professional Gb
Primary
Secondary
T-cell Lymphoma Other Serious NotSpecified 3/22/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Physician Gb
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Other Serious NotSpecified 3/22/2013 Other Health Professional Gb
Primary
Secondary
Thrombocytopenia Other Serious 6 Male 11/1/2012 Other Health Professional In
Primary
Secondary
Off Label Use Death NotSpecified 3/25/2013 Other Health Professional Gb
Primary
Secondary
Off Label Use Death NotSpecified 3/25/2013 Other Health Professional Gb
Primary
Secondary
Pneumonia Respiratory Syncytial Viral Death NotSpecified 3/25/2013 Other Health Professional Gb
Primary
Secondary
Venoocclusive Disease Death NotSpecified 3/25/2013 Other Health Professional Gb
Primary
Secondary
T-cell Lymphoma Death NotSpecified 3/25/2013 Other Health Professional Gb
Primary
Secondary
Sepsis Life Threatening 2/22/2013 7 Male 8/28/2013 Other Health Professional Ca
Primary
Secondary
Hypertriglyceridaemia Hospitalization 3/14/2013 1 Male 20 lb 6/6/2013 Physician Ca
Primary
Secondary
Venoocclusive Liver Disease Death 9 Male 88 lb 3/27/2013 Other Health Professional Jp
Primary
Secondary
Weight Increased Death 9 Male 88 lb 3/25/2013 Other Health Professional Jp
Primary
Secondary
Death Death NotSpecified 3/29/2013 Physician Us
Primary
Secondary
Concomitant
Micrococcal Sepsis Hospitalization 11/4/2012 1 Female 12 lb 4/3/2013 Physician Us
Primary
Secondary
Jaundice Cholestatic Other Serious 2/2013 38 Male 8/6/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/8/2013 1 Female 16 lb 4/17/2013 Physician Us
Primary
Secondary
Sinus Tachycardia Hospitalization 5/5/2013 1 Female 17 lb 6/18/2013 Physician Us
Primary
Secondary
Stomatitis Other Serious 8 Male 5/22/2013 Other Health Professional Tr
Primary
Secondary
Laryngitis Fungal Death Male 7/15/2013 Other Health Professional Gb
Primary
Secondary
Oesophageal Stenosis Other Serious 8 Male 5/28/2013 Other Health Professional Tr
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 8 Male 5/29/2013 Other Health Professional Tr
Primary
Secondary
Concomitant
Monoparesis Disability 17 Male 5/24/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Hemiparesis Disability 15 Female 5/24/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Speech Disorder Other Serious 15 Male 5/24/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Paresis Disability 14 Male 5/24/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Monoparesis Other Serious 14 Male 5/24/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Hemiparesis Disability 14 Male 5/24/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Epilepsy Hospitalization 10 Male 6/2/2013 Other Health Professional Cn
Primary
Secondary
Tumour Lysis Syndrome Death 17 Male 5/30/2013 Physician Cn
Primary
Secondary
Sepsis Death 15 Male 5/30/2013 Physician Cn
Primary
Secondary
Tumour Lysis Syndrome Other Serious 11 Male 6/5/2013 Physician Cn
Primary
Secondary
Epilepsy Hospitalization 10 Male 6/6/2013 Cn
Primary
Secondary
Hepatocellular Injury Hospitalization 7/27/2011 45 Male 6/14/2013 Physician Fr
Primary
Secondary
Concomitant
Off Label Use Death NotSpecified 6/24/2013 Physician Us
Primary
Secondary
Concomitant
Off Label Use Other Serious NotSpecified 6/25/2013 Physician Us
Primary
Secondary
Concomitant
Ventriculo-peritoneal Shunt Other Serious NotSpecified 7/9/2013 Physician Us
Primary
Secondary
Concomitant
Tonic Clonic Movements Hospitalization 10 Male 7/3/2013 Other Health Professional Cn
Primary
Secondary
Drug Ineffective Other Serious NotSpecified 7/10/2013 Other Health Professional De
Primary
Secondary
Concomitant
Wheezing Disability NotSpecified 5/29/2013 Physician Gb
Primary
Secondary

Drug Data