Cyclophosphamide combined with Cytarabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Disseminated Intravascular Coagulation Other Serious 12/21/2005 Female 42 lb 12/27/2005 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/18/2001 53 Male 95 lb 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 12/12/2005 72 Male 1/12/2006 France
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/21/2005 Female 138 lb 1/17/2006 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/6/2005 Female 152 lb 1/19/2006 United States
Primary
Secondary
Respiratory Distress Hospitalization 12/9/2005 72 Male 163 lb 1/20/2006 Physician France
Primary
Secondary
Concomitant
Pancreatitis Necrotising Hospitalization 9/30/2005 7 Female 53 lb 1/23/2006 United States
Primary
Concomitant
Refusal Of Treatment By Relative Other Serious 1/5/2006 Female 124 lb 1/19/2006 United States
Primary
Secondary
Subarachnoid Haemorrhage Other Serious Female 1/30/2006 Other Health Professional France
Primary
Secondary
Speech Disorder Hospitalization 11/14/2005 20 Female 218 lb 1/26/2006 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Death 6 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/19/2006 Female 125 lb 1/26/2006 United States
Primary
Secondary
Therapy Non-responder Death Female 1/27/2006 United Kingdom
Primary
Secondary
Vomiting Death Female 1/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Therapeutic Response Decreased Other Serious 1/1/2004 9 Female 66 lb 2/3/2006 Physician Japan
Primary
Secondary
Weight Decreased Other Serious 6 Female 1/28/2006 Physician United States
Primary
Secondary
Peripheral Motor Neuropathy Other Serious 1/4/2006 5 Female 35 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 2/3/2006 Physician Japan
Primary
Secondary
Vomiting Required Intervention 1/27/2006 Male 95 lb 2/6/2006 United States
Primary
Secondary
Venoocclusive Liver Disease Other Serious 1/11/2006 11 Male 77 lb 2/14/2006 Consumer United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2006 3 Male 29 lb 2/15/2006 Consumer United States
Primary
Concomitant
Febrile Neutropenia Other Serious 2/4/2006 Male 163 lb 2/14/2006 United States
Primary
Secondary
Urinary Incontinence Hospitalization 4/1/1998 16 Male 2/15/2006 Physician Spain
Primary
Secondary
Concomitant
Tongue Paralysis Life Threatening 17 Male 2/15/2006
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/2/2006 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 2/12/2006 Female 119 lb 2/27/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia 27 Male 1/23/2006 Pharmacist United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 9 Female 66 lb 3/6/2006 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 4/1/1998 16 Male 3/1/2006 Physician Spain
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/8/2006 Physician Japan
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 2/11/2006 Female 179 lb 3/3/2006 United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/10/2006 Physician Japan
Primary
Secondary
Viraemia Other Serious 28 Male 3/10/2006 Japan
Primary
Concomitant
Trichosporon Infection Other Serious 1/1/2004 30 Male 3/9/2006 Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 9 Female 66 lb 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/2004 68 Male 152 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 2/14/2006 Female 23 lb 3/7/2006 United States
Primary
Secondary
Tremor Required Intervention 3/14/2006 67 Male 159 lb 3/17/2006 United States
Primary
Secondary
Urinary Incontinence Hospitalization 48 Female 3/15/2006
Primary
Concomitant
Polyuria Other Serious 13 Female 3/17/2006 United States
Primary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 8/27/2005 63 Female 3/22/2006 Physician France
Primary
Secondary
Concomitant
Trichosporon Infection Other Serious 1/1/2004 30 Male 3/29/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 1/13/2006 71 Male 137 lb 4/3/2006 Physician France
Primary
Secondary
Concomitant
Rash Required Intervention 4/4/2006 Germany
Primary
Concomitant
Breast Cancer Female Other Serious 28 Female 4/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/3/2006 Male 23 lb 4/12/2006 United States
Primary
Secondary
Respiratory Distress Life Threatening 4/18/2006 Female 143 lb 4/19/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 4/24/2006 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Other Serious 28 Female 5/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 4/18/2006 18 Female 143 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 10 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 16 Male 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 3/1/1997 16 Male 5/1/2006 Physician Spain
Primary
Secondary
Respiratory Distress Life Threatening 4/18/2006 18 Female 143 lb 5/12/2006 Pharmacist United States
Primary
Concomitant
Stem Cell Transplant Other Serious 2/13/2005 66 Female 5/15/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/7/2006 70 Female 5/12/2006 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 80 Female 5/24/2006 Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 17 Male 5/18/2006
Primary
Secondary
Death Death 50 Male 5/23/2006 United States
Primary
Secondary
Pyrexia Other Serious 8 Female 6/2/2006 Japan
Primary
Concomitant
Transplant Rejection Other Serious 14 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Dizziness Other Serious 6/5/2006 Male 196 lb 6/7/2006 United States
Primary
Secondary
Thrombocytopenic Purpura Other Serious 16 Male 6/2/2006 Physician Canada
Primary
Secondary
Idiopathic Thrombocytopenic Purpura Other Serious 10 Female 6/3/2006 Physician Canada
Primary
Secondary
Plasmacytoma Other Serious 3/1/2002 Female 5/30/2006 Physician Japan
Primary
Secondary
Tri-iodothyronine Free Increased Other Serious 42 Male 6/16/2006 Physician Japan
Primary
Concomitant
Thyroxine Free Increased Other Serious 32 Female 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Pneumonia Required Intervention 64 Male 6/16/2006 Physician Germany
Primary
Concomitant
Tachypnoea Death 4/4/2006 43 Male 163 lb 6/20/2006 Physician Spain
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/18/2002 63 Female 143 lb 6/20/2006 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/28/2006 Female 160 lb 6/30/2006 United States
Primary
Secondary
Pancytopenia Death 5/10/2006 49 Female 216 lb 6/30/2006 France
Primary
Secondary
Sepsis Hospitalization 5/10/2006 49 Female 6/29/2006 France
Primary
Secondary
Thrombocytopenia Hospitalization 7/2/2006 Male 9 lb 7/5/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 6/28/2006 Female 50 lb 7/7/2006 United States
Primary
Secondary
Staphylococcal Infection Hospitalization 5/9/2006 Female 171 lb 7/7/2006 United States
Primary
Secondary
Haemoglobin Decreased Hospitalization 7/4/2006 Male 179 lb 7/13/2006 United States
Primary
Secondary
Weight Decreased Hospitalization 1/1/2000 50 Male 7/12/2006 United Kingdom
Primary
Secondary
Concomitant
Urosepsis Hospitalization 6/27/2006 Female 176 lb 7/13/2006 United States
Primary
Secondary
Septic Embolus 8/24/2005 Male 179 lb 7/19/2006 United States
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Insulin-like Growth Factor Decreased Other Serious 15 Male 122 lb 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Convulsion Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 6/28/2006 Female 50 lb 7/27/2006 United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 10 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 14 Male 8/3/2006 Consumer United States
Primary
Secondary
Blood Growth Hormone Decreased Other Serious 12 Female 8/4/2006 Other Health Professional United States
Primary
Secondary
Epiphyseal Disorder Other Serious 15 Male 8/4/2006 Other Health Professional United States
Primary
Secondary
Idiopathic Thrombocytopenic Purpura Other Serious 13 Female 7/31/2006 Physician Canada
Primary
Secondary
Thrombocytopenic Purpura Other Serious 16 Male 7/31/2006 Physician Canada
Primary
Secondary
Thrombocytopenic Purpura Other Serious 10 Female 7/31/2006 Physician Canada
Primary
Secondary
Cerebral Atrophy Hospitalization 11/9/2004 68 Female 106 lb 8/7/2006 Physician France
Primary
Secondary
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
Ventricular Dysfunction Hospitalization 7/10/2006 Male 194 lb 8/10/2006 United States
Primary
Secondary
Growth Hormone Deficiency Other Serious 12 Female 8/7/2006 United States
Primary
Secondary
Growth Hormone Deficiency Other Serious 15 Male 8/7/2006 United States
Primary
Secondary
Vomiting Hospitalization 8/14/2006 Female 180 lb 8/15/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/23/2006 Male 53 lb 8/24/2006 United States
Primary
Secondary
Urticaria Generalised Hospitalization 8/25/2006 Female 33 lb 8/29/2006 United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 58 Female 9/1/2006 United States
Primary
Secondary
Renal Impairment Other Serious 35 Male 9/5/2006 Japan
Primary
Secondary
Concomitant
Urinary Incontinence Required Intervention 16 Male 9/1/2006 Other Health Professional Spain
Primary
Concomitant
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 9/7/2006 Physician Portugal
Primary
Concomitant
Urticaria Generalised Hospitalization 8/25/2006 Female 33 lb 9/1/2006 United States
Primary
Secondary
Renal Impairment Other Serious 35 Male 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2006 Female 180 lb 9/5/2006 United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 56 Male 9/11/2006 United States
Primary
Secondary
Septic Shock Life Threatening 8/29/2006 50 Male 9/18/2006 Physician Israel
Primary
Concomitant
Myocardial Fibrosis Other Serious 55 Male 9/15/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 65 Male 9/15/2006 Japan
Primary
Secondary
Pulmonary Embolism Hospitalization 8/23/2006 Male 53 lb 9/12/2006 United States
Primary
Secondary
Viraemia Other Serious 28 Male 9/23/2006 Japan
Primary
Concomitant
Urinary Incontinence Required Intervention 1/1/1997 16 Male 9/20/2006 Other Health Professional Spain
Primary
Concomitant
Viral Infection Other Serious 45 Female 9/20/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Male 9/21/2006 France
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 56 Male 9/21/2006 Physician United States
Primary
Secondary
Leukoencephalopathy Other Serious 56 Male 10/3/2006 Other Health Professional United States
Primary
Secondary
Viraemia Other Serious 28 Male 10/2/2006 Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 56 Male 10/4/2006 United States
Primary
Secondary
Pneumomediastinum Other Serious 35 Male 10/11/2006
Primary
Secondary
Therapy Non-responder Hospitalization 1/1/2006 Female 108 lb 10/12/2006 Physician Portugal
Primary
Concomitant
Pain In Extremity Other Serious 11/1/1998 43 Male 10/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 40 Male 10/6/2006 United States
Primary
Secondary
Sepsis Death 34 Male 10/17/2006 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 56 Male 10/13/2006 Physician United States
Primary
Secondary
Spinal Compression Fracture Other Serious 11/1/1998 43 Male 10/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 9/21/2006 Male 168 lb 10/11/2006 United States
Primary
Secondary
Weight Decreased Life Threatening 63 Female 174 lb 10/25/2006 Other Health Professional Germany
Primary
Secondary
Staphylococcal Infection Hospitalization 10/9/2006 Male 52 lb 10/20/2006 United States
Primary
Secondary
Parosmia Disability 63 Female 11/3/2006 Other Health Professional Germany
Primary
Secondary
Concomitant

Drug Data