Cyclobenzaprine combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gastrointestinal Disorder Other Serious 9/1/2007 27 Female 10/26/2007 United States
Primary
Concomitant
Multi-organ Disorder Hospitalization 9/1/2007 27 Female 11/15/2007 United States
Primary
Concomitant
Thyroid Cancer Other Serious 1/1/2007 27 Female 11/15/2007 United States
Primary
Concomitant
Muscle Spasms Hospitalization 10/1/2007 27 Female 204 lb 12/14/2007 Physician United States
Primary
Concomitant
Dizziness Other Serious 3/6/2008 51 Female 168 lb 3/13/2008 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 3/17/2008 51 Female 168 lb 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2008 31 Female 4/11/2008 United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2008 31 Female 5/20/2008 Physician United States
Primary
Concomitant
Thyroid Mass 1/1/2007 27 Female 6/24/2008 Physician United States
Primary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/13/2009 Female 3/16/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Fungal Hospitalization 4/1/2008 57 Female 3/23/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Hospitalization 4/13/2008 57 Female 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 11/1/2007 56 Male 380 lb 4/17/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Death 1/13/2009 Female 4/24/2009 Physician United States
Primary
Secondary
Concomitant
Vulvovaginal Candidiasis Other Serious 8/22/2001 43 Female 318 lb 5/20/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/1/1997 47 Male 163 lb 5/21/2009 United States
Primary
Secondary
Concomitant
Flushing Female 5/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 40 Female 6/2/2009 United States
Primary
Concomitant
Product Quality Issue Death 11/15/2007 Female 150 lb 7/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2005 45 Female 246 lb 7/16/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/1999 40 Female 134 lb 7/16/2009 United States
Primary
Concomitant
Flushing 11/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Skin Discolouration 3/5/2009 Female 8/22/2009 United States
Primary
Concomitant
Diabetic Coma Other Serious 8/30/2003 33 Female 113 lb 9/23/2009 United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious Female 225 lb 9/23/2009 United States
Primary
Concomitant
Myositis 4/19/2000 60 Female 248 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus 1/1/2005 38 Female 9/23/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus 9/1/2006 28 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/13/2009 Female 12/1/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/30/2004 51 Male 390 lb 1/13/2010 United States
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 59 Female 1/15/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 48 Male 390 lb 2/3/2010 United States
Primary
Concomitant
Pain Other Serious 6/1/2009 Female 146 lb 2/8/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2001 48 Male 390 lb 3/2/2010 United States
Primary
Concomitant
Visual Field Defect Other Serious 4/21/2005 Female 149 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Other Serious 5/1/2007 Female 149 lb 3/8/2010 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Other Serious 5/1/2007 Female 149 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 5/1/2007 Female 149 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Death 11/15/2007 Female 150 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paranoia Other Serious Male 190 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 5/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 1/1/2007 51 Female 162 lb 5/7/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Male 190 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2001 48 Male 390 lb 5/14/2010 United States
Primary
Concomitant
Paranoia Other Serious Male 190 lb 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Paranoia Other Serious Male 190 lb 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2005 34 Female 169 lb 5/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Intestinal Haematoma Hospitalization 4/9/2010 59 Female 218 lb 4/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 7/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 7/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2008 35 Female 207 lb 8/3/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 12/18/2002 65 Female 8/6/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2006 52 Female 189 lb 8/16/2010 Lawyer United States
Primary
Concomitant
Rash Macular 1/1/2010 38 Male 290 lb 8/28/2010 United States
Primary
Concomitant
Paraesthesia 3/10/2010 59 Male 192 lb 8/29/2010 United States
Primary
Concomitant
Pancreatitis Other Serious Male 9/20/2010 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 5/1/2010 37 Female 217 lb 9/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wisdom Teeth Removal Other Serious 5/1/2007 62 Female 149 lb 10/7/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 3/17/2010 27 Male 146 lb 11/29/2010 Consumer United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 5/1/2007 62 Female 149 lb 12/23/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Mass 9/1/2010 53 Female 1/14/2011 Other Health Professional United States
Primary
Concomitant
Cholecystitis Chronic Other Serious 3/14/2008 17 Female 103 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 3/1/2008 28 Female 203 lb 4/4/2011 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis Hospitalization 2/16/2011 49 Female 146 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 5/7/2003 50 Female 240 lb 4/7/2011 Consumer United States
Primary
Concomitant
Plantar Fasciitis Other Serious 6/27/2001 4/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Gallbladder Cholesterolosis Hospitalization 1/1/2008 25 Female 290 lb 4/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Staphylococcal Hospitalization 6/1/2006 47 Female 153 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Intervertebral Disc Degeneration Other Serious 6/27/2001 4/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Amnesia Other Serious 6/27/2001 5/4/2011 United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 6/27/2001 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Palpitations Other Serious 4/25/2011 35 Female 121 lb 5/16/2011 Consumer United States
Primary
Concomitant
Dental Caries Other Serious 5/1/2007 62 Female 149 lb 5/23/2011 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/14/2003 6/2/2011 United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 4/25/2011 35 Female 121 lb 6/6/2011 Consumer United States
Primary
Concomitant
Cholesterosis Other Serious 1/1/2008 25 Female 290 lb 6/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrophic Vulvovaginitis Other Serious 10/14/2003 6/21/2011 Pharmacist United States
Primary
Secondary
Concomitant
Cholecystitis Chronic Other Serious 1/1/2008 32 Female 139 lb 6/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Depression Other Serious 8/1/2008 48 Female 7/5/2011 Lawyer United States
Primary
Concomitant
Therapeutic Response Decreased 1/1/2011 46 Female 188 lb 7/21/2011 Consumer United States
Primary
Concomitant
Diverticulum Intestinal Hospitalization 10/14/2003 7/26/2011 Pharmacist United States
Primary
Secondary
Concomitant
Muscular Weakness Disability 10/1/2010 55 Female 185 lb 8/8/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Hospitalization 28 Female 130 lb 8/8/2011 Lawyer United States
Primary
Concomitant
Amnesia Hospitalization 10/14/2003 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/14/2003 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Cholesterosis Hospitalization 1/1/2008 25 Female 290 lb 9/5/2011 Physician United States
Primary
Concomitant
Injury Hospitalization 1/1/2008 25 Female 290 lb 9/6/2011 Lawyer United States
Primary
Concomitant
Cholecystitis Chronic Other Serious 1/1/2008 25 Female 290 lb 9/5/2011 Lawyer United States
Primary
Concomitant
Pain In Extremity Other Serious 3/1/2008 28 Female 203 lb 10/4/2011 Other Health Professional United States
Primary
Concomitant
Fall Other Serious 10/14/2009 64 Female 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Iatrogenic Injury Other Serious 6/4/2010 45 Female 246 lb 10/4/2011 Physician United States
Primary
Secondary
Concomitant
Gallbladder Disorder Other Serious 4/14/2009 30 Female 175 lb 10/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 4/14/2009 61 Female 196 lb 10/25/2011 Lawyer United States
Primary
Concomitant
Bone Pain Disability 7/2/2011 58 Female 11/7/2011 Physician United States
Primary
Concomitant
Back Pain Other Serious 8/1/2009 40 Female 135 lb 11/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 32 Female 166 lb 11/8/2011 Other Health Professional United States
Primary
Concomitant
Eye Haemorrhage Other Serious 12/1/2002 51 Female 11/8/2011 United States
Primary
Concomitant
Gallbladder Disorder Other Serious 7/1/2010 31 Female 191 lb 11/14/2011 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Tract Irritation Other Serious 11/4/2004 39 Female 246 lb 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Chronic Other Serious 4/14/2009 30 Female 175 lb 11/28/2011 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 53 Female 12/16/2011 Physician United States
Primary
Concomitant
Back Pain Other Serious 8/1/2009 40 Female 135 lb 12/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Maternal Exposure During Pregnancy Other Serious Female 12/29/2011 Consumer United States
Primary
Concomitant
Maternal Exposure During Pregnancy Other Serious Female 1/3/2012 Lawyer United States
Primary
Concomitant
Migraine Hospitalization 10/8/2011 36 Female 205 lb 1/20/2012 Physician United States
Primary
Concomitant
Migraine Other Serious 10/8/2011 36 Female 205 lb 1/31/2012 Physician United States
Primary
Concomitant
Exostosis Hospitalization Female 2/6/2012 Consumer United States
Primary
Concomitant
Nausea Other Serious 10/8/2011 36 Female 205 lb 2/24/2012 Physician United States
Primary
Concomitant
Anxiety Other Serious Female 3/8/2012 Lawyer United States
Primary
Concomitant
Cleft Lip Congenital Anomaly Male 3/8/2012 Lawyer United States
Primary
Concomitant
Hip Deformity Other Serious 9/8/2009 58 Female 3/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Infusion Site Reaction Other Serious 60 Female 90 lb 3/23/2012 Physician United States
Primary
Concomitant
Postpartum Depression Other Serious Female 4/24/2012 Other Health Professional United States
Primary
Concomitant
Meniscus Lesion Other Serious 9/2/2009 54 Female 182 lb 4/26/2012 Lawyer United States
Primary
Concomitant
Cleft Palate Congenital Anomaly Male 5/4/2012 Lawyer United States
Primary
Concomitant
Application Site Rash Other Serious 4/20/2012 42 Female 112 lb 5/8/2012 Consumer United States
Primary
Secondary
Concomitant
Eustachian Tube Dysfunction Hospitalization Male 5/8/2012 Lawyer United States
Primary
Concomitant
Skin Burning Sensation Other Serious 42 Female 112 lb 5/8/2012 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 9/8/2009 58 Female 5/21/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Fungal Infection Hospitalization Female 152 lb 5/21/2012 Lawyer United States
Primary
Concomitant
Myalgia Disability 7/2/2011 58 Female 6/6/2012 Physician United States
Primary
Concomitant
Muscle Rupture Hospitalization 9/8/2009 58 Female 5/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Graft Hospitalization 9/8/2009 58 Female 6/8/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Brain Injury Hospitalization 12/2/1999 43 Female 181 lb 6/22/2012 Consumer United States
Primary
Concomitant
Fracture Displacement Other Serious 9/8/2009 58 Female 6/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 11/14/2011 53 Female 6/28/2012 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 3/30/2011 44 Female 210 lb 7/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 3/30/2011 44 Female 210 lb 7/5/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Procedural Vomiting Hospitalization 4/27/2010 30 Female 126 lb 7/9/2012 Consumer United States
Primary
Concomitant
Hypospadias Congenital Anomaly Male 7/10/2012 Lawyer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 12/2/1999 43 Female 181 lb 8/3/2012 Consumer United States
Primary
Concomitant
Quality Of Life Decreased Hospitalization Female 8/10/2012 Consumer United States
Primary
Secondary
Concomitant
Muscle Injury Other Serious 9/8/2009 58 Female 8/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Sclerosis Hospitalization 4/1/2012 53 Female 121 lb 8/24/2012 Other Health Professional United States
Primary
Concomitant
Oesophagitis Other Serious Female 192 lb 10/31/2012 Lawyer Us
Primary
Concomitant
Ulcer Other Serious 2008 41 Female 311 lb 8/20/2012 Lawyer Us
Primary
Concomitant
Surgery Life Threatening 12/2/1999 44 Female 181 lb 10/5/2012 Consumer Us
Primary
Concomitant
Procedural Haemorrhage Congenital Anomaly Male 11/23/2012 Consumer Us
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/7/2011 30 Female 10/5/2012 Consumer Us
Primary
Secondary
Concomitant
Wheezing 6/12/2012 56 Female 235 lb 10/26/2012 Physician Us
Primary
Concomitant
Injection Site Pain 9/9/2011 45 Female 225 lb 11/13/2012 Physician Us
Primary
Concomitant
Prolonged Pregnancy Other Serious Female 11/23/2012 Consumer Us
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 5/2007 Female 149 lb 9/26/2012 Consumer Us
Primary
Concomitant

Drug Data