Cyclobenzaprine combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Type 2 Diabetes Mellitus Death 60 Male 8/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Skin Discolouration 3/5/2009 Female 8/22/2009 United States
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Nocardiosis Hospitalization Female 9/10/2009 Physician United States
Primary
Concomitant
Wheezing Death 60 Male 9/4/2009 United States
Primary
Concomitant
Injury Other Serious 62 Male 200 lb 9/8/2009 United States
Primary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Wound Infection Death 56 Male 325 lb 9/22/2009 United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 11/17/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 56 Male 325 lb 11/17/2009 United States
Primary
Concomitant
Sinus Congestion 6/15/2009 12/9/2009 Physician United States
Primary
Concomitant
Vasculitis Life Threatening 3/30/2009 74 Female 262 lb 12/9/2009 Pharmacist United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 52 Female 12/11/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious Female 12/14/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 8/24/2009 Female 158 lb 1/15/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/13/2010 United States
Primary
Concomitant
Wound Hospitalization 1/7/2007 49 Male 1/8/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Unevaluable Event Other Serious 74 Male 1/13/2010 United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 62 Male 229 lb 1/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/4/2006 Female 2/18/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 74 Male 2/5/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 74 Male 2/5/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 2/19/2010 United States
Primary
Concomitant
Visual Field Defect Other Serious 4/21/2005 Female 149 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Other Serious 5/1/2007 Female 149 lb 3/8/2010 Other Health Professional United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Visual Field Defect Other Serious 5/1/2007 Female 149 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 5/1/2007 Female 149 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/7/2010 United States
Primary
Concomitant
Urinary Retention Other Serious 60 Male 236 lb 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Swelling Other Serious 12/26/2008 45 Female 170 lb 5/10/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Swelling Other Serious 12/26/2008 45 Female 170 lb 5/11/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Thrombosis Other Serious 2/13/2008 75 Female 170 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 176 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/1/2008 75 Female 170 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Burning Sensation 11/1/2009 54 Male 195 lb 8/29/2010 Consumer United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 5/1/2007 62 Female 149 lb 10/7/2010 Other Health Professional United States
Primary
Concomitant
Vein Disorder Other Serious 41 Female 11/1/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2006 48 Female 152 lb 11/19/2010 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2006 48 Female 152 lb 11/22/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Tremor Other Serious 3/1/2005 23 Female 220 lb 12/20/2010 Pharmacist United States
Primary
Secondary
Concomitant
Wisdom Teeth Removal Other Serious 5/1/2007 62 Female 149 lb 12/23/2010 Other Health Professional United States
Primary
Concomitant
Vein Disorder Other Serious 11/17/2010 41 Female 246 lb 12/23/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Constipation 1/17/2011 56 Male 1/19/2011 Consumer United States
Primary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 2/25/2009 33 Female 134 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Depressed Mood Life Threatening 12/1/2008 45 Female 170 lb 1/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 2/1/2008 75 Female 170 lb 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Pain Other Serious 2/25/2009 38 Female 134 lb 3/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Cholecystitis Chronic Hospitalization 3/1/2005 23 Female 220 lb 3/17/2011 Physician United States
Primary
Secondary
Concomitant
Constipation 1/17/2011 56 Male 3/29/2011 Consumer United States
Primary
Concomitant
Cellulitis Staphylococcal Hospitalization 6/1/2006 47 Female 153 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Conversion Disorder Disability 12/1/2008 45 Female 170 lb 4/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 12/1/2008 45 Female 170 lb 4/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/25/2009 38 Female 134 lb 4/28/2011 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Bone Pain Other Serious 4/15/2011 74 Male 5/13/2011 United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 8/27/2000 67 Male 205 lb 5/17/2011 Lawyer United States
Primary
Concomitant
Breast Cancer Female Other Serious 6/10/2003 56 Female 119 lb 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 6/10/2003 56 Female 119 lb 5/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Dental Caries Other Serious 5/1/2007 62 Female 149 lb 5/23/2011 Other Health Professional United States
Primary
Concomitant
Polymyositis 69 Female 6/5/2011 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage Disability 12/1/2008 45 Female 170 lb 6/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 5/5/2011 57 Female 6/15/2011 United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 49 Female 6/17/2011 Consumer United States
Primary
Concomitant
Platelet Count Increased Other Serious 11/1/2005 41 Female 7/28/2011 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/11/2005 26 Female 130 lb 8/2/2011 Lawyer United States
Primary
Concomitant
Breast Cancer Female Other Serious 6/10/2003 56 Female 119 lb 8/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Bladder Disorder Other Serious 6/14/2004 58 Female 155 lb 8/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Bladder Disorder Other Serious 6/14/2004 58 Female 155 lb 9/6/2011 United States
Primary
Secondary
Concomitant
Confusional State Disability 12/1/2008 45 Female 170 lb 9/7/2011 Consumer United States
Primary
Secondary
Concomitant
Death Death 8/24/2011 52 Male 9/11/2011 Other Health Professional United States
Primary
Concomitant
Hyperlipidaemia Hospitalization 6/14/2004 58 Female 155 lb 10/12/2011 United States
Primary
Secondary
Concomitant
Liver Disorder Death Male 10/18/2011 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/16/2006 71 Female 11/9/2011 Lawyer United States
Primary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Erythema 10/7/2011 Female 12/9/2011 Pharmacist United States
Primary
Concomitant
Drug Hypersensitivity Female 12/9/2011 Pharmacist United States
Primary
Secondary
Concomitant
Depression Hospitalization 56 Male 300 lb 11/23/2011 Lawyer United States
Primary
Concomitant
Crepitations Hospitalization Male 12/12/2011 Lawyer United States
Primary
Concomitant
Feeling Abnormal Male 173 lb 1/9/2012 Consumer United States
Primary
Concomitant
Hepatic Cirrhosis Death 1/1/1994 34 Male 1/23/2012 Physician United States
Primary
Concomitant
Rash Pruritic 12/1/2010 47 Female 1/27/2012 Consumer United States
Primary
Concomitant
Injection Site Pain Other Serious 41 Female 1/28/2012 Consumer United States
Primary
Concomitant
Gastritis Other Serious 62 Male 229 lb 1/31/2012 Lawyer United States
Primary
Concomitant
Feeling Abnormal Male 174 lb 2/10/2012 Physician United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/1/2012 55 Female 2/17/2012 Other Health Professional United States
Primary
Concomitant
Retching Other Serious 1/1/2012 55 Female 3/2/2012 Other Health Professional United States
Primary
Concomitant
Motor Dysfunction Other Serious 52 Female 5/2/2012 Consumer United States
Primary
Concomitant
Fungal Infection Hospitalization Female 152 lb 5/21/2012 Lawyer United States
Primary
Concomitant
Back Pain Hospitalization 3/23/2012 79 Female 187 lb 5/10/2012 Pharmacist United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 57 Male 5/29/2012 Consumer United States
Primary
Secondary
Ventricular Extrasystoles Other Serious 74 Male 276 lb 6/7/2012 Consumer United States
Primary
Concomitant
Atrial Flutter Hospitalization 1/1/2012 68 Female 6/13/2012 Physician United States
Primary
Concomitant
Migraine Hospitalization 4/1/2009 42 Female 6/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Endometrial Ablation Other Serious 4/1/2009 42 Female 6/14/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 6/14/2004 58 Female 155 lb 8/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 12/2008 45 Female 170 lb 11/16/2012 Consumer Us
Primary
Concomitant
Retching Life Threatening 1/2012 55 Female 1/26/2013 Other Health Professional Us
Primary
Concomitant
Off Label Use Hospitalization 6/27/2012 36 Female 168 lb 11/12/2012 Consumer Us
Primary
Concomitant
Off Label Use Hospitalization 6/27/2012 36 Female 168 lb 11/14/2013 Consumer Us
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 9/2012 Female 1/23/2013 Other Health Professional Us
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 7/2012 Male 11/30/2012 Consumer Us
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/21/2012 Physician Us
Primary
Concomitant
Weight Fluctuation Hospitalization 2004 55 Female 123 lb 1/16/2013 Us
Primary
Concomitant
Psoriasis Female 225 lb 1/28/2013 Other Health Professional Country Not Specified
Primary
Secondary
Concomitant
Vena Cava Thrombosis Other Serious 10/14/2009 25 Female 170 lb 5/16/2013 Lawyer Us
Primary
Secondary
Concomitant
Rash 3/28/2012 41 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Renal Tubular Disorder Other Serious 8/30/2009 56 Female 4/26/2013 Lawyer Us
Primary
Secondary
Concomitant
Death Death 3/24/2013 62 Female 213 lb 4/3/2013 Pharmacist Us
Primary
Concomitant
Dyspnoea Hospitalization 12/12/2012 66 Female 5/6/2013 Consumer Us
Primary
Concomitant
Haemorrhagic Anaemia Hospitalization 10/14/2012 49 Female 5/6/2013 Pharmacist Us
Primary
Concomitant
Subdural Haemorrhage Other Serious 80 Female 9/3/2013 Consumer Us
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/2013 59 Female 7/24/2013 Physician Us
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 6/21/2013 64 Male 12/20/2013 Physician Us
Primary
Concomitant
Myocardial Infarction Death 6/19/2013 54 Male 7/4/2013 Consumer Us
Primary
Concomitant
Weight Increased Other Serious 61 Female 190 lb 7/17/2013 Us
Primary
Concomitant
Weight Increased 49 Female 7/25/2013 Consumer Us
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 9/16/2009 33 Female 245 lb 7/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 2013 58 Female 200 lb 12/10/2013 Consumer Us
Primary
Secondary
Concomitant
Deafness Other Serious 2012 Female 9/30/2013 Physician Us
Primary
Concomitant
Myocardial Infarction Death 12/2/2012 52 Female 12/12/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 12/26/2012 72 Male 206 lb 12/5/2013 Consumer Us
Primary
Concomitant
Injection Site Swelling 22 Female 122 lb 10/2/2013 Physician Us
Primary
Concomitant
Application Site Swelling 7/31/2012 70 Female 10/4/2013 Consumer Us
Primary
Concomitant
Wound Complication Hospitalization 12/18/2006 43 Female 8/30/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/14/2004 58 Female 155 lb 8/6/2013 Consumer Us
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 5/2007 Female 149 lb 9/26/2012 Consumer Us
Primary
Concomitant

Drug Data