Cyclobenzaprine combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Incontinence Other Serious 11/18/2003 Female 220 lb 10/13/2006 Physician United States
Primary
Concomitant
Death Death 32 Female 10/30/2008 Physician United States
Primary
Secondary
Death Death 32 Female 10/31/2008 Physician United States
Primary
Secondary
Mouth Ulceration Other Serious 1/16/2009 Male 243 lb 2/11/2009 United States
Primary
Concomitant
Respiratory Arrest Hospitalization 23 Female 3/5/2009 Physician United States
Primary
Secondary
Urticaria Other Serious 11/6/2008 67 Male 220 lb 3/25/2009 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 23 Female 3/28/2009 Physician United States
Primary
Secondary
Mouth Ulceration Other Serious 1/16/2009 Male 243 lb 4/1/2009 United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 3/25/2009 57 Female 3/27/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pyrexia Required Intervention 1/10/2009 30 Male 3/24/2009 Pharmacist United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 3/25/2009 57 Female 170 lb 5/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/17/2006 Female 7/13/2009 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Death 11/15/2007 Female 150 lb 7/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 8/19/2009 Male 181 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 181 lb 9/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 12/1/2003 65 Female 190 lb 9/14/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2004 43 Female 168 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Gastroenteritis Other Serious 1/1/2005 36 Female 230 lb 9/23/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 181 lb 9/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Death 7/8/2009 53 Male 127 lb 12/29/2009 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 44 Male 1/14/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 1/20/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 44 Male 1/20/2010 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death 37 Female 1/21/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 37 Female 1/20/2010 United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 56 Female 1/21/2010 United States
Primary
Concomitant
Respiratory Arrest Death 44 Male 1/25/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 37 Female 1/25/2010 Physician United States
Primary
Secondary
Urinary Tract Infection Other Serious 1/1/2003 Female 2/8/2010 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 2/12/2010 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2008 44 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 37 Female 2/2/2010 Physician United States
Primary
Secondary
Serotonin Syndrome Hospitalization 41 Male 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 2/19/2010 Other Health Professional United States
Primary
Concomitant
Cardio-respiratory Arrest Death 37 Female 2/23/2010 Physician United States
Primary
Secondary
Drug Abuse Death 44 Male 2/23/2010 Physician United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 56 Female 260 lb 2/5/2010 United States
Primary
Concomitant
Cardio-respiratory Arrest Death 37 Female 2/26/2010 Other Health Professional Denmark
Primary
Secondary
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Female 120 lb 3/22/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 10/16/2003 Female 276 lb 3/24/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Death 1/1/2008 37 Female 240 lb 3/19/2010 Physician United States
Primary
Secondary
Urinary Retention Other Serious 1/1/2008 44 Male 220 lb 3/19/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Death 11/15/2007 Female 150 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Scar Other Serious 1/1/2008 47 Male 204 lb 4/6/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
Urobilin Urine Present Other Serious 1/1/2010 28 Female 120 lb 4/19/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/19/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 5/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Urobilin Urine Present Other Serious 1/1/2010 28 Female 120 lb 5/12/2010 United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2002 43 Male 6/1/2010 Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 176 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
International Normalised Ratio Increased 47 Female 227 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 7/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/21/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 57 Female 162 lb 7/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 5/31/2005 33 Female 165 lb 7/23/2010 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Sedation Death 11/15/2007 50 Female 150 lb 7/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 7/28/2010 United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/18/2002 65 Female 8/6/2010 Consumer United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 41 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Vomiting Other Serious 1/1/2008 50 Male 161 lb 8/18/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 5/31/2005 33 Female 165 lb 9/8/2010 United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2010 55 Female 124 lb 9/9/2010 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Somnambulism Other Serious 11/22/2009 73 Female 10/6/2010 Lawyer United States
Primary
Secondary
Somnambulism Other Serious Female 10/8/2010 Lawyer United States
Primary
Secondary
Somnambulism Other Serious 11/22/2009 73 Female 10/11/2010 Consumer United States
Primary
Secondary
Vomiting Other Serious 1/1/2008 50 Male 161 lb 10/12/2010 Lawyer United States
Primary
Concomitant
Nausea Other Serious 1/28/2008 26 Female 212 lb 10/18/2010 Physician United States
Primary
Concomitant
Nausea Other Serious 1/28/2008 26 Female 212 lb 10/19/2010 Physician United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 10/21/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/23/2010 49 Male 154 lb 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 10/29/2010 United States
Primary
Secondary
Concomitant
Somnambulism Death 11/22/2009 72 Female 10/25/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 44 Male 452 lb 11/9/2010 Lawyer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 11/21/2010 56 Male 12/9/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 12/23/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Hydronephrosis Other Serious 5/30/1996 48 Female 1/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Arthralgia 8/3/2010 46 Male 1/29/2011 Consumer United States
Primary
Concomitant
Renal Atrophy Other Serious 5/30/1996 48 Female 2/10/2011 United States
Primary
Secondary
Concomitant
Anxiety Other Serious 5/30/1996 48 Female 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 8/1/2008 28 Male 185 lb 2/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Interacting
Abdominal Pain Upper 7/19/2010 58 Female 181 lb 2/28/2011 Consumer United States
Primary
Concomitant
Hydronephrosis Hospitalization 1/19/2011 67 Male 207 lb 2/28/2011 Physician United States
Primary
Concomitant
Adhesion Hospitalization Female 166 lb 3/15/2011 Other Health Professional United States
Primary
Concomitant
Alcohol Abuse Other Serious 7/1/2004 43 Male 282 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Nephrogenic Anaemia Other Serious 1/19/2011 67 Male 207 lb 3/4/2011 Physician United States
Primary
Concomitant
Vaginal Infection Other Serious 9/1/2001 63 Female 142 lb 3/29/2011 United States
Primary
Secondary
Concomitant
Biliary Fibrosis Hospitalization 5/25/2005 27 Female 280 lb 4/6/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2008 38 Female 165 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Drug Tolerance Other Serious 4/14/2011 Other Health Professional United States
Primary
Secondary
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/1/2001 63 Female 142 lb 5/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Other Serious 1/1/2010 27 Female 323 lb 5/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Presbyopia Other Serious 9/1/2001 63 Female 142 lb 5/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/1/2008 24 Female 165 lb 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 4/15/2011 74 Male 5/13/2011 United States
Primary
Concomitant
Tooth Abscess Other Serious 10/16/2003 57 Female 276 lb 5/13/2011 Physician United States
Primary
Concomitant
Cholecystitis Chronic Other Serious 1/1/2010 27 Female 323 lb 6/1/2011 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/30/2011 79 Female 6/16/2011 Pharmacist United States
Primary
Concomitant
Hepatic Failure Hospitalization 9/20/2010 52 Female 9/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Culture Positive Death 2/10/2011 79 Female 6/9/2011 Pharmacist United States
Primary
Concomitant
Leukaemia Plasmacytic Other Serious 1/1/2004 41 Female 217 lb 6/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 1/1/2006 53 Male 6/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization 49 Female 6/17/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 8/5/2004 51 Male 173 lb 7/8/2011 Lawyer United States
Primary
Concomitant
Cardiac Arrest Death 1/1/2008 44 Male 7/18/2011 Physician United States
Primary
Secondary
Performance Status Decreased Death 4/20/2011 54 Male 7/22/2011 Pharmacist United States
Primary
Concomitant
Toxicity To Various Agents Death 1/1/2008 37 Female 7/21/2011 Physician United States
Primary
Secondary
Death Hospitalization 6/29/2011 58 Male 161 lb 7/28/2011 Pharmacist United States
Primary
Concomitant
Death Death 4/1/2011 54 Male 7/28/2011 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 7/14/2011 42 Female 196 lb 8/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 8/1/2008 29 Female 126 lb 8/25/2011 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 11/1/2009 61 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bladder Disorder Other Serious 6/14/2004 58 Female 155 lb 8/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 12/1/2003 65 Female 142 lb 9/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Bladder Disorder Other Serious 6/14/2004 58 Female 155 lb 9/6/2011 United States
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization 6/14/2004 58 Female 155 lb 10/12/2011 United States
Primary
Secondary
Concomitant
Gallbladder Disorder Other Serious 1/1/2010 27 Female 322 lb 10/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Gallbladder Non-functioning Hospitalization 1/1/2010 27 Female 322 lb 10/20/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data