Cyclobenzaprine combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Other Serious 1/1/1998 Female 3/17/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint 7/4/2005 76 Female 190 lb 3/29/2006 Consumer United States
Primary
Concomitant
Overdose Life Threatening 50 Male 10/24/2006 Physician United States
Primary
Concomitant
Interacting
Lumbar Radiculopathy Hospitalization 11/12/2008 Male 198 lb 1/23/2009 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Other Serious 4/1/2008 49 Male 2/24/2009 Consumer United States
Primary
Secondary
Demyelination Other Serious 7/1/2008 Female 189 lb 3/12/2009 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 11/4/2002 Female 3/23/2009 Lawyer United States
Primary
Secondary
Concomitant
Poisoning Other Serious 4/1/2008 49 Male 163 lb 3/24/2009 Consumer United States
Primary
Secondary
Myocardial Infarction Hospitalization 9/1/2005 45 Female 200 lb 4/10/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 8/18/2009 Lawyer United States
Primary
Concomitant
Skin Burning Sensation 5/20/2009 Male 222 lb 8/22/2009 United States
Primary
Concomitant
Tremor 4/10/2009 Female 8/22/2009 United States
Primary
Secondary
Concomitant
Pruritus Generalised 4/16/2009 Male 248 lb 8/22/2009 United States
Primary
Concomitant
Breast Cancer Other Serious 11/4/2002 Female 10/6/2009 Lawyer United States
Primary
Secondary
Concomitant
Venous Insufficiency Hospitalization 69 Female 11/18/2009 Consumer United States
Primary
Concomitant
Wrong Drug Administered Hospitalization 10/6/2009 84 Female 195 lb 10/15/2009 Pharmacist United States
Primary
Concomitant
Drug Toxicity Hospitalization 25 Female 1/21/2010 Other Health Professional United States
Primary
Secondary
Dry Mouth 4/1/2009 67 Male 1/29/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 77 Male 159 lb 3/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/20/2009 Female 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Poor Quality Sleep Other Serious 1/1/2010 63 Female 168 lb 3/31/2010 Consumer United States
Primary
Concomitant
Anosmia 12/1/2008 62 Female 134 lb 4/5/2010 United States
Primary
Concomitant
Troponin T Increased Other Serious 3/27/2010 61 Male 201 lb 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Post Procedural Stroke Hospitalization 5/20/2009 65 Male 130 lb 4/28/2010 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 82 Male 4/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Eye Irritation 2/18/2009 74 Female 205 lb 5/6/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 77 Male 159 lb 5/6/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Troponin T Increased Other Serious 3/27/2010 61 Male 201 lb 5/7/2010 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 5/1/2010 55 Male 5/26/2010 Physician United States
Primary
Secondary
Concomitant
Costochondritis 56 Female 228 lb 6/16/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Vertebral Foraminal Stenosis Other Serious 11/17/2004 51 Female 180 lb 6/17/2010 United States
Primary
Secondary
Concomitant
Vertebral Foraminal Stenosis Other Serious 11/17/2004 51 Female 180 lb 6/24/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 47 Female 227 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Throat Irritation 5/8/2008 69 Female 7/7/2010 Other Health Professional United States
Primary
Concomitant
Shock Life Threatening 9/13/2009 40 Female 7/6/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Troponin T Increased Other Serious 3/27/2010 61 Male 90 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Anosmia 12/1/2008 62 Female 134 lb 4/5/2010 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2008 60 Female 142 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Hospitalization 7/3/2010 65 Male 110 lb 8/7/2010 Pharmacist United States
Primary
Concomitant
Vein Disorder Other Serious 2/25/2008 52 Female 209 lb 8/11/2010 Lawyer United States
Primary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 46 Male 178 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea 6/18/2010 63 Male 240 lb 8/29/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 50 Male 161 lb 10/12/2010 Lawyer United States
Primary
Concomitant
Knee Arthroplasty Other Serious 8/26/2010 78 Female 10/13/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 178 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 10/27/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 3/1/2009 54 Female 11/10/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 11/11/2010 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 11/15/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 2/1/2010 89 Female 11/16/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 46 Male 179 lb 11/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 11/19/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2006 48 Female 152 lb 11/19/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 57 Female 11/11/2010 United States
Primary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/1/2010 61 Male 189 lb 12/16/2010 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/1/2010 61 Male 189 lb 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Discolouration 5/1/2010 50 Female 155 lb 11/6/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Nephrolithiasis Hospitalization 12/4/2010 63 Female 150 lb 12/29/2010 Other Health Professional United States
Primary
Concomitant
Headache 12/31/2010 74 Male 1/18/2011 Consumer
Primary
Concomitant
Monocyte Count Decreased Hospitalization 10/1/2005 52 Female 180 lb 1/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Dizziness Female 165 lb 1/29/2011 Consumer Puerto Rico
Primary
Concomitant
Balance Disorder 5/7/2010 58 Female 1/29/2011 Consumer United States
Primary
Concomitant
Intentional Overdose Other Serious 6/1/2007 54 Female 2/2/2011 Lawyer United States
Primary
Concomitant
Injection Site Erythema Other Serious 11/27/2009 22 Female 203 lb 2/10/2011 Consumer United States
Primary
Concomitant
Amnesia Other Serious 1/1/2009 62 Female 2/15/2011 Consumer United States
Primary
Concomitant
Aortic Aneurysm Other Serious 1/1/2004 69 Male 142 lb 3/7/2011 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Other Serious 2/28/2011 62 Male 251 lb 3/9/2011 Physician United States
Primary
Concomitant
Mental Disorder Death 6/1/2007 54 Female 3/11/2011 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 2/1/2008 52 Female 209 lb 3/25/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 2/1/2010 89 Female 3/29/2011 Consumer United States
Primary
Concomitant
Arrhythmia Other Serious Female 3/25/2011 Consumer United States
Primary
Concomitant
Injection Site Haematoma Other Serious 1/1/2009 62 Female 4/6/2011 Consumer United States
Primary
Concomitant
Anhedonia Hospitalization 12/15/2005 56 Male 146 lb 4/18/2011 Consumer United States
Primary
Concomitant
Confusional State Other Serious 2/1/2010 54 Male 278 lb 4/18/2011 Physician United States
Primary
Concomitant
Pyelonephritis Hospitalization 10/1/2002 36 Female 276 lb 4/21/2011 United States
Primary
Concomitant
Skin Ulcer Hospitalization 6/1/2010 62 Male 4/20/2011 Consumer United States
Primary
Concomitant
Anhedonia Hospitalization 7/13/2007 67 Female 120 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Cellulitis Staphylococcal Hospitalization 6/1/2006 47 Female 153 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 69 Male 142 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Other Serious 6/27/2001 4/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/1/2009 61 Female 7/26/2011 Lawyer United States
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/11/2011 71 Male 197 lb 8/22/2011 Physician United States
Primary
Concomitant
Arterial Occlusive Disease Other Serious 2/1/2010 58 Male 200 lb 8/22/2011 Consumer United States
Primary
Concomitant
Asthenia Other Serious 2/1/2010 89 Female 8/23/2011 Consumer United States
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/11/2011 71 Male 197 lb 8/25/2011 Physician United States
Primary
Concomitant
Amnesia Hospitalization 10/14/2003 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/14/2003 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Depression Hospitalization 6/1/2008 51 Male 10/11/2011 Lawyer United States
Primary
Concomitant
Seasonal Affective Disorder Other Serious 1/1/2010 66 Female 225 lb 11/4/2011 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 7/6/2009 44 Female 170 lb 12/19/2011 Lawyer United States
Primary
Concomitant
Mental Status Changes Death 6/21/2011 82 Male 12/27/2011 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious Male 1/1/2012 Physician United States
Primary
Concomitant
Chest Pain Other Serious Male 1/2/2012 Lawyer United States
Primary
Concomitant
Confusional State Hospitalization 6/1/2010 44 Female 260 lb 1/18/2012 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered By Device Death 8/20/2011 74 Female 194 lb 1/26/2012 Physician United States
Primary
Concomitant
Constipation 1/1/2008 54 Male 2/2/2012 Consumer United States
Primary
Concomitant
Arteriovenous Malformation Hospitalization 3/23/2009 58 Female 163 lb 2/8/2012 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2011 58 Female 260 lb 4/3/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Decreased 3/13/2012 50 Female 168 lb 4/13/2012 Consumer United States
Primary
Concomitant
Joint Injury Other Serious 10/1/2011 58 Female 260 lb 4/19/2012 Consumer United States
Primary
Secondary
Concomitant
Sinus Disorder Other Serious 1/1/2011 51 Female 162 lb 5/18/2012 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 11/2/2007 78 Female 182 lb 6/7/2012 Consumer United States
Primary
Concomitant
Osteoporosis Hospitalization 1/1/2007 49 Female 6/11/2012 Consumer United States
Primary
Concomitant
Bone Marrow Failure Hospitalization 1/19/2011 67 Male 207 lb 6/1/2012 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2011 51 Female 161 lb 6/28/2012 Consumer United States
Primary
Concomitant
Sinus Disorder Other Serious 1/1/2011 52 Female 161 lb 8/3/2012 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2010 46 Female 173 lb 8/21/2012 Consumer United States
Primary
Concomitant
Weight Decreased Death 2004 Male 142 lb 11/6/2012 Consumer Us
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious Male 211 lb 10/12/2012 Lawyer Us
Primary
Concomitant
Weight Increased Other Serious 12/2010 46 Female 173 lb 9/19/2012 Physician Us
Primary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 1/19/2011 67 Male 207 lb 10/25/2012 Physician Us
Primary
Concomitant
Toxicity To Various Agents Death 3/5/2008 57 Female 150 lb 10/12/2012 Physician Us
Primary
Secondary
Concomitant
Tremor Other Serious 9/2008 Female 100 lb 9/17/2012 Lawyer Us
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 143 lb 9/25/2012 Lawyer Us
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/2004 32 Female 201 lb 9/13/2012 Consumer Us
Primary
Concomitant
Pulmonary Granuloma Other Serious 1/2012 Male 157 lb 9/12/2012 Physician Us
Primary
Concomitant
Pruritus Hospitalization 11/27/2011 52 Female 9/13/2012 Us
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/12/2009 43 Female 275 lb 11/12/2012 Consumer Us
Primary
Secondary
Concomitant
Nightmare 2009 45 Male 280 lb 12/9/2012 Consumer Us
Primary
Concomitant
Somnolence 2008 44 Male 280 lb 12/9/2012 Consumer Us
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 46 Male 280 lb 11/28/2012 Consumer Us
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 11/2012 Female 336 lb 2/21/2013 Consumer Us
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/20/2012 Physician Us
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/21/2012 Physician Us
Primary
Concomitant
Tachycardia Hospitalization 12/5/2012 76 Female 12/28/2012 Other Health Professional Us
Primary
Concomitant
Toxicity To Various Agents Death Female 1/8/2013 Physician Us
Primary
Secondary
Death Death 61 Female 1/15/2013 Physician Us
Primary
Secondary
Tardive Dyskinesia Disability Female 1/17/2013 Physician Us
Primary
Concomitant
Toxicity To Various Agents Hospitalization 61 Female 1/18/2013 Physician Us
Primary
Secondary
Completed Suicide Death Female 1/18/2013 Physician Country Not Specified
Primary
Secondary
Completed Suicide Death 2011 Female 1/18/2013 Physician Us
Primary
Secondary
Completed Suicide Death Female 1/20/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 30 Female 1/18/2013 Physician Us
Primary
Secondary
Nausea 1/2011 57 Female 190 lb 10/28/2012 Other Health Professional Us
Primary
Concomitant

Drug Data