Cyclobenzaprine combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Erectile Dysfunction Other Serious 1/1/2006 56 Male 209 lb 3/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Lumbar Radiculopathy Hospitalization 11/12/2008 Male 198 lb 1/23/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 10/1/2008 Female 194 lb 2/24/2009 Other Health Professional Canada
Primary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 3/5/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 235 lb 3/6/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 3/25/2009 United States
Primary
Concomitant
Chest Pain Hospitalization 12/7/2008 Female 5/18/2009 United States
Primary
Secondary
Concomitant
Drug Screen Positive 6/1/2009 Physician
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 45 Male 224 lb 6/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 6/22/2009 Physician United States
Primary
Concomitant
Phaeochromocytoma Other Serious 4/21/2008 Female 136 lb 7/1/2009 Other Health Professional United States
Primary
Concomitant
Flushing 9/5/2008 Female 8/22/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 202 lb 10/26/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 202 lb 12/16/2009 United States
Primary
Concomitant
Death Death 11/4/2009 66 Male 399 lb 12/22/2009 Other Health Professional United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2009 Female 1/22/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 51 Female 202 lb 1/25/2010 United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 62 Male 229 lb 1/22/2010 United States
Primary
Concomitant
Dyspepsia 6/1/2009 71 Female 203 lb 2/22/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Female 165 lb 2/23/2010 Consumer United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 165 lb 4/8/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/7/2010 United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 1/1/2008 48 Female 238 lb 4/21/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/5/2010 62 Female 4/20/2010 United States
Primary
Concomitant
Wound Dehiscence Hospitalization 9/11/2009 65 Male 309 lb 5/6/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 6/11/2010 United States
Primary
Concomitant
Costochondritis 56 Female 228 lb 6/16/2010 United States
Primary
Secondary
Concomitant
Skin Infection Other Serious 7/1/2009 49 185 lb 6/18/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 56 Female 149 lb 6/29/2010 Consumer United States
Primary
Concomitant
Drug Ineffective Female 276 lb 7/31/2010 Physician United States
Primary
Concomitant
Sciatic Nerve Neuropathy 5/1/2009 70 Male 222 lb 8/4/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 51 Male 8/4/2010 United States
Primary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 8/17/2010 United States
Primary
Secondary
Concomitant
Haematoma Hospitalization 5/19/2010 62 Female 183 lb 8/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 7/1/2010 47 Female 260 lb 9/3/2010 Consumer United States
Primary
Concomitant
Malaise Hospitalization 8/29/2010 62 Female 176 lb 9/9/2010 Other Health Professional Canada
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 56 Female 149 lb 9/16/2010 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/18/2003 45 Male 286 lb 9/20/2010 United States
Primary
Concomitant
Malaise Hospitalization 8/29/2010 62 Female 176 lb 9/20/2010 Other Health Professional Canada
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 1/1/2009 62 Female 9/16/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 64 Male 144 lb 9/21/2010 United States
Primary
Concomitant
Malaise Hospitalization 8/29/2010 62 Female 176 lb 9/24/2010 Other Health Professional Canada
Primary
Concomitant
Arthritis Bacterial Hospitalization 7/19/2010 66 Male 309 lb 9/24/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/8/2010 United States
Primary
Concomitant
Pain Hospitalization Female 10/22/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/26/2010 United States
Primary
Concomitant
Toe Operation Hospitalization 9/15/2009 54 Female 190 lb 10/29/2010 Other Health Professional Canada
Primary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 11/17/2010 United States
Primary
Secondary
Concomitant
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2010 65 Female 210 lb 12/13/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 56 Female 149 lb 6/29/2010 Consumer United States
Primary
Concomitant
Pneumonia 12/18/2009 12/16/2010 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 5/1/2010 73 Female 1/13/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/11/2010 43 Female 1/21/2011 Other Health Professional United States
Primary
Secondary
Dizziness Hospitalization 8/12/2008 36 Female 161 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/1/2010 19 Female 255 lb 1/28/2011 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization Male 240 lb 1/28/2011 Consumer United States
Primary
Concomitant
Injection Site Pain 10/24/2010 57 Male 294 lb 1/30/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2010 63 Female 176 lb 2/9/2011 Consumer United Kingdom
Primary
Concomitant
Bundle Branch Block Left Other Serious 62 Female 331 lb 1/26/2011 United States
Primary
Concomitant
Palpitations 62 Female 2/24/2011 Pharmacist United States
Primary
Concomitant
Heart Rate Increased 62 Female 2/24/2011 Pharmacist United States
Primary
Concomitant
Constipation Other Serious 7/6/1998 47 Male 258 lb 3/2/2011 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 1/12/2011 66 Female 3/7/2011 Consumer Switzerland
Primary
Concomitant
Sepsis Death 2/24/2011 81 Female 171 lb 3/12/2011 Consumer United States
Primary
Concomitant
Cholelithiasis Other Serious Female 280 lb 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 2/24/2011 81 Female 171 lb 3/22/2011 Consumer United States
Primary
Concomitant
Hypertension Other Serious Female 203 lb 3/31/2011 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haematoma Other Serious 1/1/2009 62 Female 4/6/2011 Consumer United States
Primary
Concomitant
Abdominal Pain 1/11/2011 61 Male 4/15/2011 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 8/14/2010 68 Male 4/15/2011 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 8/14/2010 68 Male 4/28/2011 Pharmacist United States
Primary
Concomitant
Injury Other Serious 1/1/2010 27 Female 323 lb 5/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2009 53 Female 160 lb 5/9/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/5/2010 62 Female 8/19/2011 Physician United States
Primary
Concomitant
Osteomyelitis Hospitalization 2/22/2011 55 Female 190 lb 8/19/2011 Other Health Professional Canada
Primary
Concomitant
Mood Swings Other Serious Female 203 lb 9/6/2011 Physician United States
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 5/1/2010 53 Female 207 lb 12/26/2011 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 11/1/2011 59 Male 2/2/2012 Physician United States
Primary
Concomitant
Drug Ineffective 9/20/2011 68 Female 185 lb 3/15/2012 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2011 66 Female 158 lb 4/4/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Decreased 3/13/2012 50 Female 168 lb 4/13/2012 Consumer United States
Primary
Concomitant
Eye Haemorrhage Other Serious 1/1/2011 66 Female 158 lb 4/27/2012 Consumer United States
Primary
Secondary
Concomitant
Dry Mouth Other Serious 1/1/2011 66 Female 158 lb 6/11/2012 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Male 177 lb 7/18/2012 Consumer United States
Primary
Concomitant
Drug Ineffective 8/6/2012 65 Male 256 lb 8/15/2012 Consumer United States
Primary
Concomitant
Neoplasm Malignant Other Serious 4/1/2010 63 Male 155 lb 8/22/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/2010 19 Female 255 lb 2/25/2013 Consumer Us
Primary
Secondary
Concomitant
Tremor Other Serious Female 145 lb 10/12/2012 Lawyer Us
Primary
Concomitant
Ulcer Other Serious 2008 41 Female 311 lb 8/20/2012 Lawyer Us
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2010 63 Male 155 lb 9/26/2012 Consumer Us
Primary
Secondary
Concomitant
Injection Site Pain Other Serious Female 1/25/2013 Consumer Br
Primary
Concomitant
Pulmonary Embolism Hospitalization 45 Female 8/28/2012 Consumer Us
Primary
Secondary
Concomitant
Herpes Virus Infection Hospitalization 10/2011 Female 278 lb 10/4/2012 Physician Us
Primary
Concomitant
Pain 12/2012 48 Male 320 lb 3/28/2013 Consumer Us
Primary
Concomitant
Death Death 8/19/2012 57 Male 8/29/2012 Other Health Professional Us
Primary
Concomitant
Pruritus Hospitalization 12/2011 Male 187 lb 9/14/2012 Consumer Us
Primary
Concomitant
Feeling Abnormal 42 Female 9/20/2012 Physician Us
Primary
Concomitant
Palpitations 53 Female 9/24/2012 Other Health Professional Us
Primary
Concomitant
Staphylococcal Infection Hospitalization 2007 33 Female 12/12/2012 Consumer Us
Primary
Concomitant
Skin Necrosis Hospitalization 5/15/2012 49 Female 252 lb 9/24/2012 Pharmacist Us
Primary
Concomitant
Respiratory Failure Other Serious 5/2012 Female 121 lb 10/15/2012 Pharmacist Us
Primary
Concomitant
Hypothermia Hospitalization 1/19/2012 50 Male 154 lb 10/23/2012 Pharmacist Br
Primary
Concomitant
Injection Site Swelling Female 214 lb 10/24/2012 Physician Us
Primary
Concomitant
Feeling Abnormal 10/22/2012 48 Female 1/31/2013 Physician Us
Primary
Concomitant
Skin Irritation 7/4/2011 51 Female 10/24/2012 Other Health Professional Us
Primary
Concomitant
Swelling 4/14/2010 46 Female 12/24/2012 Physician Us
Primary
Secondary
Concomitant
Off Label Use Hospitalization 6/27/2012 36 Female 168 lb 11/12/2012 Consumer Us
Primary
Concomitant
Swelling 5/30/2010 46 Female 12/24/2012 Physician Us
Primary
Concomitant
Diarrhoea Hospitalization 11/20/2012 51 Male 181 lb 11/21/2012 Us
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 11/20/2012 51 Male 181 lb 3/12/2013 Physician Us
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 11/28/2012 75 Male 160 lb 12/5/2012 Pharmacist Us
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/5/2012 76 Female 12/28/2012 Other Health Professional Us
Primary
Concomitant
Polycystic Ovaries Other Serious 27 12/27/2012 Other Health Professional Us
Primary
Concomitant
Skin Cancer Other Serious 3/2012 61 Female 107 lb 4/30/2013 Pharmacist Us
Primary
Concomitant
Toxicity To Various Agents Death Female 1/8/2013 Physician Us
Primary
Secondary
Tardive Dyskinesia Disability Female 1/17/2013 Physician Us
Primary
Concomitant
Completed Suicide Death Female 1/18/2013 Physician Country Not Specified
Primary
Secondary
Completed Suicide Death Female 1/20/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 30 Female 1/18/2013 Physician Us
Primary
Secondary
Diarrhoea Hospitalization 11/20/2012 51 Male 181 lb 12/20/2012 Us
Primary
Secondary
Concomitant
Completed Suicide Death Female 1/28/2013 Other Health Professional Us
Primary
Secondary
Headache Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Obstruction Hospitalization 12/25/2012 Female 234 lb 2/12/2013 Other Health Professional Ca
Primary
Concomitant
Unevaluable Event 11/25/2012 43 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Drug Ineffective 9/2011 Male 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pain 6/21/2012 45 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Renal Failure Hospitalization 12/25/2012 66 Female 237 lb 1/31/2013 Pharmacist Us
Primary
Concomitant
Ocular Hyperaemia 8/2012 51 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Blood Glucose Increased 5/14/2012 62 Female 215 lb 2/18/2013 Consumer Country Not Specified
Primary
Concomitant
Productive Cough 12/6/2012 53 Female 330 lb 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Urinary Tract Infection 8/2012 Female 230 lb 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Haematochezia Hospitalization 12/21/2011 49 Female 251 lb 4/20/2013 Consumer Us
Primary
Concomitant
Respiratory Arrest Death NotSpecified 2/18/2013 Physician Us
Primary
Secondary
Drug Ineffective 2/12/2013 65 Male 202 lb 2/19/2013 Consumer Us
Primary
Concomitant
Vomiting 11/2012 62 Female 2/19/2013 Other Health Professional Us
Primary
Concomitant
Respiratory Arrest Death 2011 Female 2/1/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 Female 1/31/2013 Physician Us
Primary
Secondary
Completed Suicide Death 2011 Female 2/4/2013 Other Health Professional Us
Primary
Secondary
Type 2 Diabetes Mellitus 2008 64 Female 209 lb 3/7/2013 Consumer Us
Primary
Concomitant
Surgery Other Serious Female 198 lb 3/8/2013 Other Health Professional Ca
Primary
Concomitant
Dizziness Other Serious 2011 57 Male 270 lb 3/20/2013 Consumer Us
Primary
Concomitant
Dizziness 2010 56 Male 270 lb 3/21/2013 Consumer Us
Primary
Concomitant
Weight Decreased Other Serious 2008 60 Female 10/29/2012 Physician Us
Primary
Concomitant
Withdrawal Syndrome 2012 Female 217 lb 3/22/2013 Consumer Us
Primary
Concomitant
Neuropathy Peripheral Disability 70 Male 9/19/2012 Pharmacist Us
Primary
Concomitant

Drug Data