Cyclobenzaprine combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Response Decreased Other Serious 7/19/2005 Male 3/27/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 62 Female 10/30/2006 Consumer United States
Primary
Concomitant
Muscle Spasms Hospitalization 10/1/2007 27 Female 204 lb 12/14/2007 Physician United States
Primary
Concomitant
Mania Hospitalization 6/1/2007 59 Male 228 lb 2/26/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 9/20/2008 54 Male 9/22/2008 United States
Primary
Secondary
Concomitant
Pruritus Male 2/24/2009 United States
Primary
Concomitant
Somnolence Life Threatening 11/10/2008 52 Male 234 lb 3/16/2009 Other Health Professional United States
Primary
Concomitant
Incorrect Route Of Drug Administration 3/1/2009 Female 233 lb 4/10/2009 Consumer United States
Primary
Concomitant
Weight Increased Required Intervention 3/19/2009 Female 4/13/2009 Pharmacist United States
Primary
Concomitant
Vocal Cord Disorder Other Serious 11/1/2007 56 Male 380 lb 4/17/2009 Lawyer United States
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 3/25/2009 57 Female 3/27/2009 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/17/2008 82 Female 203 lb 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Required Intervention 3/19/2009 Female 5/20/2009 Pharmacist United States
Primary
Concomitant
Respiratory Tract Infection Fungal Other Serious 1/17/2008 82 Female 203 lb 6/23/2009 Physician United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Required Intervention 3/25/2009 57 Female 170 lb 5/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 7/1/2009 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 5/1/2009 72 Male 7/2/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/17/2008 82 Female 202 lb 6/30/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 7/13/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/17/2008 82 Female 202 lb 7/17/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Respiratory Distress Other Serious 1/17/2008 82 Female 202 lb 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Feeling Hot 6/1/2009 Female 8/22/2009 United States
Primary
Concomitant
Nocardiosis Hospitalization Female 9/10/2009 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 Male 9/16/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection 7/31/2009 Female 180 lb 9/19/2009 Physician
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control 1/1/2005 26 Female 170 lb 9/23/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus 9/1/2006 28 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 56 Female 260 lb 11/20/2009 United States
Primary
Concomitant
Thinking Abnormal Life Threatening 10/29/2009 49 Male 180 lb 12/1/2009 Consumer United States
Primary
Concomitant
Serotonin Syndrome Other Serious 7/23/2007 Female 183 lb 11/30/2009 Consumer United States
Primary
Concomitant
Urticaria Other Serious 4/5/2009 Female 132 lb 12/4/2009 Pharmacist United States
Primary
Concomitant
Poor Quality Sleep Hospitalization 1/1/2009 54 Female 12/10/2009 Physician United States
Primary
Concomitant
Wrong Drug Administered Hospitalization 10/6/2009 84 Female 195 lb 10/15/2009 Pharmacist United States
Primary
Concomitant
Death Death 11/3/2009 66 Male 399 lb 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 12/22/2009 United States
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 12/22/2009 United States
Primary
Concomitant
Death Death 11/4/2009 66 Male 399 lb 12/22/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 56 Female 1/21/2010 United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 Male 2/12/2010 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/7/2009 78 Female 2/16/2010 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 78 Female 2/17/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2007 Male 3/16/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/12/2009 59 Female 77 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Mitral Valve Calcification Hospitalization 1/13/2007 77 Female 165 lb 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin T Increased Other Serious 3/27/2010 61 Male 201 lb 5/7/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/1/2009 63 Male 171 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Reaction To Drug Excipients Other Serious 11/1/2009 65 Female 168 lb 5/19/2010 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious Female 6/7/2010 United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 58 Female 215 lb 6/11/2010 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 10/9/2008 55 Female 237 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Corneal Abrasion Other Serious 6/2/2010 67 Female 6/23/2010 Consumer United States
Primary
Concomitant
Spinal Disorder Other Serious 4/22/2010 66 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Interacting
International Normalised Ratio Increased 47 Female 227 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Memory Impairment Hospitalization 6/10/2010 46 Male 194 lb 7/1/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/23/2009 63 Male 171 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 64 Female 241 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 58 Female 215 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Hypersomnia 4/2/2010 57 Female 220 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 4/4/2010 57 Female 6/21/2010 Consumer United States
Primary
Concomitant
Memory Impairment Hospitalization 6/10/2010 46 Male 194 lb 7/15/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 9/25/2008 81 Male 7/21/2010 Lawyer United States
Primary
Concomitant
Troponin T Increased Other Serious 3/27/2010 61 Male 90 lb 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 78 Female 155 lb 8/18/2010 Physician United States
Primary
Concomitant
Self Injurious Behaviour Other Serious 6/1/2009 46 Female 294 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Glossodynia 10/1/2009 76 Female 180 lb 8/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 64 Female 241 lb 9/21/2010 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/2009 52 Female 250 lb 9/22/2010 Physician United States
Primary
Secondary
Concomitant
Drug Intolerance Other Serious 64 Female 9/27/2010
Primary
Secondary
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/20/2009 48 Male 201 lb 11/3/2010 United States
Primary
Concomitant
Pain In Jaw Other Serious 11/22/2010 12/15/2010 Physician United States
Primary
Concomitant
Hypertension Other Serious 10/21/2009 12/16/2010 Consumer Brazil
Primary
Concomitant
Tooth Disorder Other Serious 11/1/2010 12/22/2010 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 12/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 8/12/2008 36 Female 161 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 62 Male 427 lb 2/1/2011 Other Health Professional United States
Primary
Concomitant
Vitreous Floaters Other Serious 1/1/2010 65 Female 250 lb 1/20/2011 Consumer United States
Primary
Concomitant
Asthma Other Serious 3/29/2000 73 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Memory Impairment Other Serious 2/1/2011 82 Female 2/24/2011 Consumer United States
Primary
Concomitant
Spinal Disorder Hospitalization 8/2/2010 58 Female 2/28/2011 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/26/2011 43 Male 175 lb 3/7/2011 United States
Primary
Concomitant
Oedema Peripheral Other Serious 9/1/2010 59 Female 3/4/2011 Consumer Brazil
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 3/10/2011 45 Female 200 lb 3/16/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Other Serious 12/30/2010 89 Female 105 lb 3/25/2011 Consumer United States
Primary
Concomitant
Hyperhidrosis Other Serious 6/27/2010 71 Female 3/18/2011 Consumer United States
Primary
Concomitant
Insomnia 1/9/2011 Female 3/30/2011 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 2/1/2010 89 Female 3/29/2011 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/26/2011 43 Male 175 lb 4/1/2011 United States
Primary
Concomitant
Arrhythmia Other Serious Female 3/25/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Lower Other Serious 6/27/2010 71 Female 4/14/2011 Consumer United States
Primary
Concomitant
Dry Mouth 4/6/2011 78 Female 4/22/2011 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 3/16/2000 28 Female 193 lb 4/24/2011 Physician Canada
Primary
Concomitant
Thrombocytopenia Other Serious 3/13/2011 60 Female 238 lb 4/19/2011 Pharmacist United States
Primary
Concomitant
Skin Ulcer Hospitalization 6/1/2010 62 Male 4/20/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2009 53 Female 160 lb 5/9/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 2/1/2011 68 Male 5/12/2011 Consumer United States
Primary
Concomitant
Intervertebral Disc Disorder Other Serious 6/1/2008 47 Female 211 lb 5/17/2011 Consumer United States
Primary
Secondary
Concomitant
Fall Other Serious Female 5/18/2011 Consumer United States
Primary
Concomitant
Headache Other Serious Female 82 lb 5/23/2011 Consumer United States
Primary
Concomitant
Tongue Disorder 5/13/2011 64 Female 6/2/2011 Consumer United States
Primary
Concomitant
Balance Disorder Hospitalization 8/12/2008 36 Female 161 lb 6/10/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 3/29/2000 73 Female 6/16/2011 Physician United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 5/1/2011 68 Female 140 lb 6/17/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 2/1/2010 89 Female 6/16/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Perforation Life Threatening Female 143 lb 6/21/2011 Physician United States
Primary
Concomitant
Neuralgia Hospitalization 1/1/2009 64 Female 161 lb 6/16/2011 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 5/15/2011 73 Female 200 lb 5/25/2011 Pharmacist United States
Primary
Concomitant
Cerumen Impaction Other Serious 2/1/2010 89 Female 7/6/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 3/15/2011 48 Female 169 lb 7/7/2011 United States
Primary
Concomitant
Ankylosing Spondylitis Other Serious 8/2/2010 58 Female 7/8/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 4/1/2009 25 Female 7/7/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Life Threatening 10/29/2009 49 Male 175 lb 7/19/2011 Consumer United States
Primary
Interacting
Fear Of Falling Other Serious 2/1/2011 68 Female 82 lb 7/22/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 3/15/2011 48 Female 169 lb 7/27/2011 United States
Primary
Concomitant
Platelet Count Increased Other Serious 11/1/2005 41 Female 7/28/2011 Consumer United States
Primary
Secondary
Concomitant
Gastric Polyps Other Serious 3/15/2011 68 Female 137 lb 7/22/2011 Physician United States
Primary
Secondary
Concomitant
Skin Induration Disability 10/1/2005 45 Female 161 lb 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 10/19/2010 67 Male 225 lb 8/5/2011 Consumer United States
Primary
Concomitant
Flushing 11/1/2010 47 Male 8/5/2011 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 1/26/2011 43 Male 175 lb 8/8/2011 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 7/14/2011 42 Female 196 lb 8/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 48 Female 8/12/2011 Consumer United States
Primary
Secondary
Concomitant
Asthenia Other Serious 2/1/2010 89 Female 8/23/2011 Consumer United States
Primary
Concomitant
Disturbance In Attention Other Serious 1/26/2011 43 Male 175 lb 9/5/2011 Physician United States
Primary
Concomitant
Disease Progression Hospitalization 7/10/2011 84 Female 175 lb 9/5/2011 Physician United States
Primary
Secondary
Concomitant
Alopecia 4/1/2011 68 Female 123 lb 9/6/2011 Consumer United States
Primary
Concomitant
Amnesia Hospitalization 12/9/2005 47 Female 125 lb 9/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious 12/9/2005 47 Female 125 lb 9/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Catecholamines Urine Increased Death 61 Female 146 lb 9/16/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Dehydration Hospitalization 61 Female 146 lb 9/23/2011 Other Health Professional
Primary
Secondary
Concomitant
Aspiration Other Serious 61 Female 146 lb 9/30/2011 Other Health Professional
Primary
Secondary
Concomitant
Alopecia Female 10/10/2011 United States
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/13/2011 58 Female 255 lb 10/18/2011 Consumer United States
Primary
Concomitant
Metanephrine Urine Increased Hospitalization 61 Female 146 lb 10/12/2011 Canada
Primary
Concomitant
Cholecystitis Chronic Hospitalization 9/1/2009 33 Female 10/25/2011 Consumer United States
Primary
Concomitant
Abdominal Distension Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Haemodynamic Instability Death 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Respiratory Failure Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Drug Level Increased Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Asthenia Other Serious 12/1/2008 65 Female 280 lb 10/27/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 8/28/2006 21 Female 362 lb 11/7/2011 Lawyer United States
Primary
Concomitant
Concomitant Disease Progression Hospitalization 7/10/2011 84 Female 175 lb 11/8/2011 Physician United States
Primary
Secondary
Concomitant
Back Pain Other Serious 8/1/2009 40 Female 135 lb 11/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/29/2011 72 Female 175 lb 11/15/2011 Physician United States
Primary
Concomitant
Renal Failure Death 61 Female 146 lb 11/18/2011 Other Health Professional Canada
Primary
Secondary
Concomitant

Drug Data