Cyclobenzaprine combined with Hydroxyzine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Suicidal Ideation Other Serious 6/1/2008 51 Female 12/30/2008 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 39 Female 1/21/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2007 39 Female 1/22/2009 Physician United States
Primary
Secondary
Poisoning Deliberate Death 54 Female 2/11/2009 Physician United States
Primary
Secondary
Respiratory Arrest Death 39 Female 3/9/2009 Physician United States
Primary
Secondary
Eyelid Ptosis Other Serious 8/4/2008 Female 134 lb 5/5/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 40 Female 166 lb 5/14/2009 United States
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 7/1/2009 United States
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 7/13/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2001 41 Female 230 lb 7/21/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 2/28/2006 45 Male 228 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Vomiting 5/26/2009 Female 230 lb 9/18/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/1/2007 68 Male 9/21/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection 1/1/2002 42 Female 196 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 12/8/2002 33 Female 172 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/15/2009 Male 167 lb 12/2/2009 Consumer United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/19/2009 Male 167 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 52 Female 12/11/2009 Lawyer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 12/10/2009 United States
Primary
Concomitant
Vomiting Other Serious Female 12/14/2009 United States
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 12/22/2009 United States
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 Male 153 lb 12/22/2009 United States
Primary
Concomitant
Completed Suicide Death 49 Female 1/12/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 1/20/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 18 Female 1/21/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious Female 1/13/2010 United States
Primary
Concomitant
Unevaluable Event Hospitalization 51 Male 1/13/2010 United States
Primary
Concomitant
Drug Toxicity Death 49 Female 1/22/2010 Other Health Professional United States
Primary
Secondary
Swollen Tongue Other Serious 7/1/2006 36 Female 215 lb 1/29/2010 Other Health Professional Canada
Primary
Concomitant
Completed Suicide Death 49 Female 1/22/2010 Belgium
Primary
Secondary
Snoring Hospitalization 51 Male 1/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant
Incorrect Drug Administration Duration Other Serious 1/17/2010 62 Female 131 lb 2/9/2010 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 18 Female 2/2/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 49 Female 2/2/2010 Physician United States
Primary
Secondary
Injection Site Haematoma 12/15/2008 74 Female 134 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 2/19/2010 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 49 Female 2/23/2010 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 10/6/2006 Female 150 lb 2/27/2010 Physician United States
Primary
Secondary
Wound Drainage Other Serious 10/29/2001 Female 144 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/29/2001 Female 144 lb 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Wound Drainage Other Serious 10/29/2001 Female 144 lb 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 10/16/2003 Female 276 lb 3/24/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia 11/1/2009 Female 3/16/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 5/20/2009 Female 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/19/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 63 Male 171 lb 4/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/7/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Incorrect Drug Administration Duration Other Serious 1/14/2010 62 Female 131 lb 5/10/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/1/2009 63 Male 171 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/12/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 5/21/2010 United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 5/13/2010 11 Male 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 5/13/2010 11 Male 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/2/2010 United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 5/13/2010 11 Male 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2002 55 Female 118 lb 6/15/2010 United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 5/13/2010 11 Male 6/17/2010 Physician United States
Primary
Concomitant
Skin Infection Other Serious 7/1/2009 49 185 lb 6/18/2010 Physician United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 4/1/2010 22 Female 203 lb 6/16/2010 United States
Primary
Concomitant
Skin Infection Other Serious 7/1/2009 49 185 lb 6/28/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 48 Female 170 lb 7/2/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 7/7/2010 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/23/2009 63 Male 171 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Crying 3/5/2007 62 Female 185 lb 7/9/2010 Consumer United States
Primary
Concomitant
Urticaria Other Serious 4/1/2010 22 Female 203 lb 7/23/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 7/28/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 8/5/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/18/2002 65 Female 8/6/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 51 Male 8/4/2010 United States
Primary
Concomitant
Vertigo Other Serious 62 Female 182 lb 8/16/2010 Lawyer United States
Primary
Concomitant
Urticaria Hospitalization 11/27/2009 22 Female 203 lb 8/25/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2005 54 Female 9/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 11/27/2009 22 Female 203 lb 9/8/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2010 55 Female 124 lb 9/9/2010 Other Health Professional Canada
Primary
Concomitant
Suicide Attempt Other Serious 6/26/2007 37 Female 9/13/2010 Lawyer United States
Primary
Concomitant
Urticaria Hospitalization 11/27/2009 22 Female 203 lb 9/16/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 10/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 7/1/2010 45 Female 199 lb 10/20/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 10/21/2010 United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 49 Female 10/28/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 9/1/2001 63 Female 142 lb 10/29/2010 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 11/27/2009 22 Female 203 lb 11/15/2010 Consumer United States
Primary
Concomitant
Suspiciousness Other Serious 1/1/2010 52 Male 11/22/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 57 Female 11/11/2010 United States
Primary
Concomitant
Suicide Attempt Other Serious 8/1/2008 22 Female 12/1/2010 Lawyer United States
Primary
Concomitant
Thinking Abnormal Other Serious 1/1/2010 52 Male 12/16/2010 Other Health Professional United States
Primary
Concomitant
Aggression 5/1/2010 69 Female 140 lb 2/3/2011 Consumer United States
Primary
Concomitant
Injection Site Erythema Other Serious 11/27/2009 22 Female 203 lb 2/10/2011 Consumer United States
Primary
Concomitant
Deformity Other Serious 1/1/2002 48 Female 170 lb 3/3/2011 United States
Primary
Concomitant
Cholecystitis Other Serious 8/30/2009 33 Female 185 lb 3/19/2011 Other Health Professional United States
Primary
Concomitant
Vaginal Infection Other Serious 9/1/2001 63 Female 142 lb 3/29/2011 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/1/2001 63 Female 142 lb 5/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Presbyopia Other Serious 9/1/2001 63 Female 142 lb 5/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 10/16/2003 57 Female 276 lb 5/13/2011 Physician United States
Primary
Concomitant
Cholecystectomy Other Serious 8/30/2009 33 Female 185 lb 6/7/2011 Lawyer United States
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 49 Female 6/17/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 49 Female 6/27/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 49 Female 7/21/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2008 18 Female 7/21/2011 Physician United States
Primary
Secondary
Intentional Drug Misuse Death 1/1/2008 49 Female 7/21/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2008 18 Female 7/21/2011 Physician United States
Primary
Secondary
Gallbladder Injury Hospitalization 42 Female 189 lb 8/3/2011 Other Health Professional United States
Primary
Concomitant
Cholelithiasis Hospitalization 42 Female 189 lb 8/3/2011 Pharmacist United States
Primary
Concomitant
Depression Other Serious 7/1/2009 52 Female 174 lb 8/4/2011 Lawyer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 12/1/2003 65 Female 142 lb 9/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2011 43 Female 111 lb 9/7/2011 Consumer United States
Primary
Concomitant
Metanephrine Urine Increased Hospitalization 61 Female 146 lb 10/12/2011 Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/1/2009 40 Female 239 lb 10/19/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/1/2009 40 Female 239 lb 10/21/2011 Lawyer United States
Primary
Concomitant
Abdominal Distension Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Haemodynamic Instability Death 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Respiratory Failure Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Drug Level Increased Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Essential Hypertension Other Serious Female 11/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 12/1/2005 25 Female 180 lb 11/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Haemodynamic Instability Death 61 Female 11/8/2011 Canada
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 10/16/2003 57 Female 276 lb 11/16/2011 Consumer United States
Primary
Concomitant
Cerumen Impaction Hospitalization Female 11/16/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 10/16/2003 57 Female 276 lb 11/18/2011 Physician United States
Primary
Concomitant
Renal Failure Death 61 Female 146 lb 11/18/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious 10/16/2003 57 Female 276 lb 11/28/2011 Lawyer United States
Primary
Concomitant
Chest Discomfort Hospitalization Female 12/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Off Label Use Hospitalization 49 Female 12/9/2011 Consumer United States
Primary
Concomitant
Ventilation Perfusion Mismatch Hospitalization 1/1/2003 29 Female 275 lb 12/23/2011 Lawyer United States
Primary
Concomitant
Cardiac Arrest Death 1/1/2010 39 Female 12/23/2011 Physician United States
Primary
Secondary
Metastases To Spine Hospitalization 1/1/2002 73 Female 144 lb 1/1/2012 Consumer United States
Primary
Secondary
Concomitant
Diverticulum Intestinal Other Serious 1/1/2002 73 Female 144 lb 1/3/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Incorrect Dose Administered By Device Other Serious 8/20/2011 74 Female 12/28/2011 Consumer United States
Primary
Concomitant
Drug Abuse Death 1/1/2010 39 Female 1/5/2012 Physician United States
Primary
Secondary
Hypertension Life Threatening 8/25/2011 49 Female 195 lb 1/12/2012 Physician United States
Primary
Concomitant
Interacting
Neck Pain Hospitalization Female 1/13/2012 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 1/1/2002 73 Female 144 lb 1/17/2012 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 1/1/2010 39 Female 1/11/2012 Physician United States
Primary
Secondary
Economic Problem Disability Female 1/12/2012 Lawyer United States
Primary
Concomitant
Interacting
Chronic Obstructive Pulmonary Disease Hospitalization 1/1/2002 73 Female 144 lb 1/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Abuse Death 1/1/2010 39 Female 1/9/2012 Physician United States
Primary
Secondary

Drug Data