Cyclobenzaprine combined with Hydrochlorothiazide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Required Intervention 5/5/2006 23 Female 7/12/2006 Pharmacist United States
Primary
Concomitant
Nausea 1/1/2007 60 Male 306 lb 7/11/2007 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 9/6/2007 69 Female 200 lb 12/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased 1/1/2007 65 Male 280 lb 4/10/2008 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 53 Male 2/24/2009 United States
Primary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Pruritus Male 2/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 2/27/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 3/5/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 44 Male 230 lb 3/25/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 1/21/2004 55 Male 198 lb 3/23/2009 United States
Primary
Concomitant
Vaginitis Bacterial Other Serious 9/1/2000 47 Female 4/15/2009 United States
Primary
Concomitant
Eyelid Ptosis Other Serious 8/4/2008 Female 134 lb 5/5/2009 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 12/7/2008 Female 5/18/2009 United States
Primary
Secondary
Concomitant
Flushing Female 5/27/2009 United States
Primary
Concomitant
Drug Screen Positive 4/28/2009 59 Male 161 lb 6/3/2009 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 59 Female 185 lb 6/4/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 45 Male 224 lb 6/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 6/22/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 10/1/2002 36 Female 276 lb 6/26/2009 United States
Primary
Concomitant
Vomiting Life Threatening 4/29/2009 Female 200 lb 6/26/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 7/1/2009 United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/5/2002 27 Female 187 lb 7/2/2009 United States
Primary
Concomitant
Vomiting Life Threatening 4/29/2009 Female 200 lb 7/8/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1993 54 Female 7/10/2009 United States
Primary
Concomitant
Transaminases Increased Hospitalization 7/17/2006 Female 7/13/2009 Other Health Professional United States
Primary
Concomitant
Insulin-requiring Type 2 Diabetes Mellitus Other Serious 3/7/2005 42 Male 221 lb 7/14/2009 United States
Primary
Concomitant
Drug Screen Positive 4/28/2009 59 Male 161 lb 7/15/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/21/2005 32 Female 204 lb 7/17/2009 United States
Primary
Concomitant
Vomiting Life Threatening 4/29/2009 Female 226 lb 7/20/2009 Consumer United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2001 41 Female 230 lb 7/21/2009 United States
Primary
Concomitant
Vomiting Life Threatening 4/29/2009 Female 226 lb 8/14/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Flushing 9/5/2008 Female 8/22/2009 United States
Primary
Concomitant
Visual Field Defect Hospitalization 61 Female 237 lb 8/21/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/3/2004 55 Female 220 lb 8/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2004 52 Female 179 lb 8/31/2009 United States
Primary
Concomitant
Injection Site Extravasation 10/4/2007 Female 251 lb 9/12/2009 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 12/1/2003 65 Female 190 lb 9/14/2009 United States
Primary
Concomitant
Injury Death 64 Female 9/10/2009 Lawyer United States
Primary
Concomitant
Vulvovaginal Candidiasis Other Serious 3/31/2002 41 Female 302 lb 9/23/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus 2/1/2001 53 Female 150 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/2002 49 Female 182 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 12/11/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/2/2001 51 Male 202 lb 1/6/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/14/2010 Physician United States
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 12/18/2009 Female 198 lb 1/19/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 1/20/2010 Other Health Professional United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Chromaturia 11/1/2009 Female 1/24/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 12/4/2009 Female 1/24/2010 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 59 Female 1/15/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 64 Female 1/21/2010 Lawyer United States
Primary
Concomitant
Injection Site Swelling 10/24/2009 Female 224 lb 1/30/2010 United States
Primary
Concomitant
Rash Macular 10/29/2009 Female 210 lb 1/30/2010 Consumer United States
Primary
Concomitant
Pain Other Serious 6/1/2009 Female 146 lb 2/8/2010 Consumer United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Flushing 12/10/2009 208 lb 2/16/2010 United States
Primary
Concomitant
Injection Site Haematoma 12/15/2008 74 Female 134 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 2/19/2010 Other Health Professional United States
Primary
Concomitant
Rash Pruritic Hospitalization 12/18/2009 Female 198 lb 3/3/2010 Consumer United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/15/2010 Physician United States
Primary
Secondary
Concomitant
Tenodesis Hospitalization 64 Female 3/5/2010 Lawyer United States
Primary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 10/16/2003 Female 276 lb 3/24/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 Female 276 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 3/23/2010 United States
Primary
Concomitant
Poor Quality Sleep Other Serious 1/1/2010 63 Female 168 lb 3/31/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/14/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/16/2003 57 Female 276 lb 4/19/2010 Other Health Professional United States
Primary
Concomitant
Stupor 3/8/2010 48 Female Physician United States
Primary
Concomitant
Pneumonia Hospitalization 4/5/2010 62 Female 4/20/2010 United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2005 34 Female 169 lb 5/28/2010 United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 58 Female 215 lb 6/11/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 63 Male 215 lb 6/18/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Pulmonary Oedema Other Serious 12/1/2008 49 Female 127 lb 7/2/2010 Consumer United States
Primary
Concomitant
Procedural Site Reaction Other Serious Female 143 lb 7/8/2010 Consumer Brazil
Primary
Concomitant
Vaginitis Bacterial Other Serious 9/1/2000 47 Female 181 lb 7/9/2010 United States
Primary
Concomitant
Productive Cough 2/1/2007 44 Female 177 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2010 58 Female 215 lb 7/12/2010 Consumer United States
Primary
Secondary
Concomitant
Rash Pruritic 5/1/2007 49 Female 168 lb 7/13/2010 Consumer United States
Primary
Concomitant
Lobar Pneumonia Hospitalization 4/5/2010 62 Female 7/8/2010 United States
Primary
Concomitant
Tobacco User 8/1/2007 47 Female 218 lb 7/15/2010 Other Health Professional United States
Primary
Concomitant
Vomiting 5/5/2007 60 Female 189 lb 7/16/2010 Other Health Professional United States
Primary
Concomitant
Skin Injury Other Serious 2/28/2007 44 Male 7/23/2010 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 51 Male 210 lb 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Fluid Retention Death Female 350 lb 7/28/2010 Consumer United States
Primary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 7/28/2010 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 5/1/2010 50 Female 110 lb 7/29/2010 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 1/11/2005 64 Female 240 lb 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Nausea Disability 11/12/2006 62 Female 220 lb 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 74 Female 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death Female 350 lb 8/5/2010 Physician United States
Primary
Concomitant
Osteoporosis Other Serious 1/1/2008 45 Female 124 lb 8/5/2010 Physician United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 2/27/2010 56 Female 252 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 74 Female 8/13/2010 United States
Primary
Secondary
Concomitant
Pleurisy Other Serious Female 8/13/2010 Consumer United States
Primary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 8/17/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2009 51 Female 138 lb 8/19/2010 Consumer United States
Primary
Secondary
Concomitant
Vertigo Other Serious 62 Female 182 lb 8/16/2010 Lawyer United States
Primary
Concomitant
Swollen Tongue 1/2/2010 57 Male 190 lb 8/28/2010 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 63 Male 250 lb 8/31/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/3/2006 68 Female 300 lb 9/1/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2005 54 Female 9/3/2010 United States
Primary
Concomitant
Vaginitis Bacterial Other Serious 9/1/2000 47 Female 181 lb 9/3/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 52 Female 138 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/1/2007 54 Female 9/9/2010 Lawyer United States
Primary
Concomitant
Muscle Rigidity Other Serious 1/1/2006 50 Male 217 lb 9/20/2010 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 5/1/2010 50 Female 110 lb 10/1/2010 Consumer United States
Primary
Concomitant
Knee Arthroplasty Other Serious 8/26/2010 78 Female 10/13/2010 Consumer United States
Primary
Concomitant
Pleurisy Other Serious Female 10/14/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 12/1/2008 49 Female 127 lb 10/19/2010 Physician United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Carcinoid Tumour Pulmonary Other Serious Female 10/27/2010 Physician United States
Primary
Concomitant
Tooth Fracture 59 Female 10/13/2010 Consumer United States
Primary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 11/17/2010 United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 6/1/2006 48 Female 152 lb 11/19/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Pain Other Serious Female 11/19/2010 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 6/1/2006 48 Female 152 lb 11/22/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 51 Female 127 lb 11/23/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Convulsion Other Serious Male 245 lb 12/7/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thinking Abnormal Other Serious 1/1/2010 52 Male 12/16/2010 Other Health Professional United States
Primary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 12/23/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Inflammation Other Serious 1/1/2011 Male 1/25/2011 Consumer United States
Primary
Secondary
Concomitant
Local Swelling 11/2/2010 57 Female 155 lb 1/30/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 62 Male 427 lb 2/1/2011 Other Health Professional United States
Primary
Concomitant
Asthma Other Serious 3/29/2000 73 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mesangioproliferative Glomerulonephritis Hospitalization 1/1/2009 48 Female 254 lb 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Alcohol Abuse Other Serious 7/1/2004 43 Male 282 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Hypertension Other Serious Female 203 lb 3/31/2011 Consumer United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious Female 3/25/2011 Consumer United States
Primary
Concomitant
Biliary Fibrosis Hospitalization 5/25/2005 27 Female 280 lb 4/6/2011 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious Female 3/29/2011 Other Health Professional United States
Primary
Secondary
Dental Caries Female 162 lb 2/7/2011 Other Health Professional United States
Primary
Concomitant

Drug Data