Cyanocobalamin combined with Pemetrexed

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypertrophy Hospitalization 2/21/2005 71 Male 198 lb 4/17/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 2/11/2007 71 Female 123 lb 5/14/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/26/2007 67 Male 150 lb 5/19/2007 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/26/2007 67 Male 150 lb 6/12/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/9/2007 75 Male 146 lb 7/1/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 7/5/2007 61 Male 121 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 7/5/2007 61 Male 121 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/2/2007 68 Male 161 lb 8/21/2007 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 8/1/2007 Male 154 lb 10/2/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2007 Male 84 lb 10/1/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/9/2007 Male 103 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 3/21/2007 Male 153 lb 11/16/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/8/2007 Male 114 lb 11/27/2007 Physician Japan
Primary
Concomitant
Hyponatraemia Other Serious 4/16/2007 Male 102 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/12/2007 Male 142 lb 11/30/2007 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 5/16/2007 Male 146 lb 12/4/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/7/2007 Male 114 lb 12/7/2007 Physician Japan
Primary
Concomitant
Ileus Hospitalization 5/19/2007 Male 174 lb 12/9/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 125 lb 12/13/2007 Physician Japan
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 8/24/2007 Male 104 lb 12/17/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/9/2007 Male 103 lb 12/29/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Life Threatening 9/28/2007 Male 127 lb 1/7/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2007 Male 103 lb 1/21/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 5/19/2007 Male 174 lb 1/30/2008 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/19/2007 Male 152 lb 2/3/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/28/2007 Male 127 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/16/2007 Male 125 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/12/2007 Male 142 lb 2/4/2008 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 10/15/2007 Male 105 lb 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/19/2007 Male 109 lb 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 8/16/2007 Male 154 lb 3/3/2008 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 12/25/2007 Male 143 lb 3/25/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 3/26/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/19/2007 Male 109 lb 4/3/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/1/2007 Male 103 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Other Serious 7/1/2007 70 Male 140 lb 4/4/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 Male 143 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Restlessness Other Serious 6/17/2007 Female 88 lb 4/18/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2007 70 Male 140 lb 5/2/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 154 lb 5/21/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/31/2008 Male 114 lb 5/21/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 7/24/2007 Male 103 lb 5/27/2008 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/17/2007 Male 152 lb 5/27/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 1/1/2008 Male 132 lb 6/16/2008 Physician Japan
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 10/10/2007 Male 105 lb 6/25/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/7/2007 Male 143 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2007 70 Male 140 lb 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Blood Uric Acid Increased Other Serious 1/11/2008 Male 141 lb 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Disability 6/15/2007 Male 108 lb 7/7/2008 Physician Japan
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 5/16/2007 Male 146 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/23/2008 Male 114 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 4/28/2008 Male 132 lb 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 5/25/2008 Male 110 lb 7/11/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/15/2008 Male 116 lb 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 2/23/2006 Female 135 lb 7/17/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2007 70 Male 140 lb 8/12/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 Male 110 lb 8/18/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/25/2008 Female 137 lb 8/18/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 12/25/2007 Male 134 lb 8/22/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/28/2008 Male 132 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/17/2007 Male 152 lb 8/29/2008 Physician Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli 8/18/2008 Male 159 lb 8/28/2008 United States
Primary
Secondary
Pneumonia Hospitalization 3/31/2008 Male 164 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 11/19/2007 Male 128 lb 9/9/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/25/2008 Female 134 lb 9/9/2008 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/19/2007 Male 121 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/16/2008 Female 115 lb 9/17/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/10/2007 Male 105 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 154 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/5/2007 Male 143 lb 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/7/2008 Male 143 lb 9/22/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 154 lb 9/24/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/23/2008 Male 114 lb 9/25/2008 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/29/2008 Male 121 lb 10/9/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/23/2008 Male 104 lb 10/16/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 6/21/2007 Male 108 lb 10/21/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/25/2007 Male 130 lb 10/29/2008 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 11/26/2007 Male 11/6/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/29/2008 Male 121 lb 11/10/2008 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 4/8/2008 Male 146 lb 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2008 Female 122 lb 12/1/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2008 Male 162 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 1/1/2008 Male 139 lb 12/29/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/25/2007 Male 154 lb 1/27/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2008 Female 122 lb 2/18/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 9/25/2008 Male 91 lb 2/27/2009 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 11/26/2007 Male 2/27/2009 Physician Japan
Primary
Concomitant
Subileus Other Serious 11/19/2007 Male 128 lb 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Hiccups Hospitalization 8/5/2008 Male 132 lb 3/6/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2008 Male 107 lb 3/5/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/13/2008 Male 137 lb 3/9/2009 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/1/2008 Male 139 lb 3/17/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 9/25/2008 Male 91 lb 3/19/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/19/2007 Male 128 lb 3/27/2009 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 4/8/2008 Male 146 lb 3/31/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/27/2008 Male 138 lb 3/31/2009 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 8/5/2008 Male 132 lb 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2008 Male 107 lb 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
No Adverse Event Male 138 lb 4/30/2009 Physician Japan
Primary
Secondary
Concomitant
Aneurysm Hospitalization 4/22/2009 Male 198 lb 5/15/2009 Physician United States
Primary
Concomitant
Aneurysm Hospitalization 4/22/2009 Male 198 lb 6/3/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 Male 110 lb 6/22/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/24/2008 Female 134 lb 6/29/2009 Physician Japan
Primary
Concomitant
Aneurysm Hospitalization 4/22/2009 Male 198 lb 7/2/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 Male 110 lb 7/5/2009 Physician Japan
Primary
Concomitant
Haemoptysis Other Serious 8/19/2009 72 Female 9/6/2009 Physician Honduras
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2007 Male 84 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/16/2007 Male 154 lb 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/25/2008 Male 110 lb 12/1/2009 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 58 Male 2/8/2010 Spain
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 1/1/2009 58 Male 2/19/2010 Other Health Professional Spain
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 58 Male 2/22/2010 Spain
Primary
Secondary
Concomitant
Splenic Rupture Other Serious 18 Male 186 lb 4/16/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Splenic Rupture Other Serious 18 Male 186 lb 4/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/21/2010 62 Male 164 lb 5/12/2010 Physician Japan
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 4/17/2010 63 Male 5/14/2010 Physician Japan
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 11/9/2009 49 Male 151 lb 5/21/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/15/2010 68 Female 117 lb 5/21/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 4/12/2010 73 Female 5/20/2010 Physician Japan
Primary
Concomitant
Aortic Dissection Life Threatening 4/21/2010 62 Male 171 lb 5/21/2010 Physician Japan
Primary
Concomitant
Iliac Artery Occlusion Hospitalization 4/17/2010 63 Male 142 lb 6/2/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 4/12/2010 73 Female 6/2/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/15/2010 68 Female 117 lb 6/3/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 3/15/2010 68 Female 117 lb 6/10/2010 Physician Japan
Primary
Concomitant
Aortic Dissection Life Threatening 4/21/2010 62 Male 171 lb 6/21/2010 Physician Japan
Primary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 6/11/2010 61 Male 151 lb 6/25/2010 Consumer Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/11/2010 61 Male 151 lb 7/4/2010 Consumer Germany
Primary
Secondary
Concomitant
Splenic Infarction Hospitalization 6/11/2010 61 Male 151 lb 7/30/2010 Consumer Germany
Primary
Secondary
Concomitant
Splenic Infarction Hospitalization 6/11/2010 61 Male 151 lb 8/4/2010 Consumer Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 8/14/2010 54 Male 159 lb 9/4/2010 Physician Germany
Primary
Secondary
Concomitant
Vertigo Hospitalization 8/14/2010 54 Male 159 lb 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/18/2010 74 Male 179 lb 9/23/2010 Physician United States
Primary
Secondary
Concomitant
Arterial Occlusive Disease Hospitalization 4/17/2010 63 Male 142 lb 10/26/2010 Physician Japan
Primary
Concomitant
Splenic Infarction Hospitalization 6/11/2010 61 Male 151 lb 10/26/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/18/2010 74 Male 179 lb 11/6/2010 Physician United States
Primary
Secondary
Concomitant
Peripheral Embolism Disability 1/7/2010 71 Male 152 lb 11/12/2010 Physician Japan
Primary
Concomitant
Quality Of Life Decreased Hospitalization 6/22/2010 72 Male 191 lb 11/15/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/7/2010 73 Male 117 lb 12/3/2010 Physician Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 8/18/2010 74 Male 179 lb 12/6/2010 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 7/1/2010 55 Female 12/8/2010 Physician Italy
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 7/1/2010 55 Female 12/8/2010 Physician Italy
Primary
Secondary
Concomitant
Constipation Hospitalization 11/24/2009 65 Male 12/10/2010 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/10/2010 59 Male 2/25/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Death 6/11/2010 61 Male 151 lb 2/28/2011 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Life Threatening 12/10/2010 59 Male 3/14/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/10/2010 59 Male 3/16/2011 Physician United States
Primary
Concomitant

Drug Data