Cyanocobalamin combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rheumatoid Arthritis Other Serious 12/25/2003 56 Female 101 lb 1/2/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/4/2005 47 Male 205 lb 1/31/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 10/4/2005 75 Male 130 lb 2/14/2006 Physician Japan
Primary
Concomitant
Sepsis Other Serious 10/4/2005 75 Male 130 lb 3/10/2006 Physician Japan
Primary
Concomitant
Pleurisy Other Serious 10/6/2005 66 Male 108 lb 3/24/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 5/22/2006 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 2/27/2006 Female 5/23/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 6/9/2006 Physician Japan
Primary
Concomitant
Polymyositis Other Serious 2/27/2006 54 Female 6/9/2006 Physician Japan
Primary
Concomitant
Polymyositis Other Serious 2/27/2006 54 Female 7/7/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 7/12/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/23/2006 73 Female 128 lb 7/13/2006 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 6/1/2006 Male 170 lb 7/21/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/10/2005 61 Female 96 lb 7/27/2006 Physician Japan
Primary
Concomitant
Restlessness Other Serious 6/1/2006 66 Male 170 lb 7/31/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/12/2006 78 Female 157 lb 8/8/2006 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/12/2006 78 Female 157 lb 8/23/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/10/2005 61 Female 96 lb 9/15/2006 Physician Japan
Primary
Concomitant
Restlessness Other Serious 6/1/2006 66 Male 170 lb 10/12/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/6/2006 35 Male 10/23/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/6/2006 35 Male 10/30/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 3/1/2006 75 Male 10/31/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Papular Other Serious 3/1/2006 Male 141 lb 11/8/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Papular Hospitalization 3/1/2006 Male 141 lb 11/16/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 3/1/2006 Male 141 lb 11/28/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 3/1/2006 Male 141 lb 12/6/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Other Serious 3/1/2006 Male 141 lb 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 6/2/2006 Male 128 lb 12/18/2006 Physician Japan
Primary
Concomitant
Lymphangiosis Carcinomatosa Life Threatening 9/21/2006 68 Male 132 lb 12/19/2006 Physician Japan
Primary
Concomitant
Urinary Incontinence Other Serious 1/9/2007 72 Female 1/22/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 12/22/2006 77 Male 126 lb 1/23/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 10/11/2006 33 Female 1/24/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/2/2007 66 Male 1/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/22/2006 77 Male 126 lb 1/30/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 2/9/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/22/2006 77 Male 126 lb 2/13/2007 Physician Japan
Primary
Concomitant
Multiple Sclerosis Other Serious 11/6/2002 18 Male 134 lb 2/13/2007 Japan
Primary
Concomitant
Encephalopathy Hospitalization 2/8/2007 65 Female 99 lb 2/15/2007 Physician Japan
Primary
Concomitant
Fatigue Hospitalization 2/8/2007 65 Female 99 lb 2/22/2007 Physician Japan
Primary
Concomitant
Fatigue Hospitalization 2/8/2007 65 Female 99 lb 3/5/2007 Physician Japan
Primary
Concomitant
Multiple Sclerosis Other Serious 11/6/2002 18 Male 134 lb 3/6/2007 Japan
Primary
Concomitant
Malaise Hospitalization 2/8/2007 65 Female 99 lb 3/16/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/5/2006 32 Female 3/21/2007 Physician Japan
Primary
Concomitant
Sepsis Other Serious 10/8/2006 Male 148 lb 3/27/2007 Physician Japan
Primary
Concomitant
Shock Other Serious 3/11/2007 68 Male 112 lb 4/4/2007 Physician Japan
Primary
Concomitant
Sepsis Other Serious 10/8/2006 Male 148 lb 4/4/2007 Physician Japan
Primary
Concomitant
Malaise Hospitalization 2/8/2007 65 Female 99 lb 4/11/2007 Physician Japan
Primary
Concomitant
Snoring Life Threatening 3/25/2007 70 Female 4/23/2007 Physician Japan
Primary
Concomitant
Pleurisy Hospitalization 9/13/2006 Male 4/26/2007 Physician Japan
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 3/27/2007 74 Female 117 lb 4/27/2007 Physician Japan
Primary
Concomitant
Toxic Induced Encephalopathy Hospitalization 3/23/2007 84 Female 5/3/2007 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 3/25/2007 85 Female 5/23/2007 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 3/25/2007 85 Female 6/4/2007 Physician Japan
Primary
Concomitant
Nervous System Disorder Hospitalization 3/27/2007 74 Female 117 lb 6/11/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 2/9/2004 Female 108 lb 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 3/25/2007 70 Female 6/21/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 2/9/2004 Female 108 lb 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 3/23/2007 84 Female 7/5/2007 Physician Japan
Primary
Concomitant
Speech Disorder Other Serious 4/12/2007 86 Female 7/5/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 7/5/2007 61 Male 121 lb 7/18/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 7/5/2007 61 Male 121 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2007 Male 84 lb 10/1/2007 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 3/21/2007 Male 153 lb 11/16/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Function Test Abnormal Life Threatening 9/11/2007 72 Male 11/27/2007 Pharmacist Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 8/1/2007 75 Male 12/3/2007 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 4/11/2007 71 Male 119 lb 12/4/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 11/27/2007 Physician Japan
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 11/7/2007 Female 110 lb 12/4/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 9/28/2007 Male 127 lb 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/7/2007 Male 114 lb 12/7/2007 Physician Japan
Primary
Concomitant
Urinary Retention Other Serious 10/28/2007 71 Male 12/11/2007 Physician Japan
Primary
Concomitant
Erythema Multiforme Other Serious 11/7/2007 Female 110 lb 12/13/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 10/19/2007 94 Female 95 lb 12/18/2007 Physician Japan
Primary
Concomitant
Oliguria Other Serious 10/31/2007 Female 12/18/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 76 Female 12/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 12/24/2007 66 Female 1/2/2008 Consumer Japan
Primary
Concomitant
Erythema Multiforme Other Serious 11/7/2007 Female 110 lb 1/2/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2007 88 Female 115 lb 1/4/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Life Threatening 9/28/2007 Male 127 lb 1/7/2008 Physician Japan
Primary
Secondary
Concomitant
Dementia Other Serious 80 1/15/2008 Pharmacist Japan
Primary
Concomitant
Renal Impairment Life Threatening 2/11/2007 72 Male 1/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/24/2007 66 Female 86 lb 1/16/2008 Consumer Japan
Primary
Concomitant
Renal Impairment Life Threatening 2/11/2007 72 Male 1/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2007 88 Female 115 lb 1/22/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 77 Female 1/22/2008 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/11/2007 72 Male 1/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/16/2008 77 Female 1/28/2008 Pharmacist Japan
Primary
Concomitant
Renal Impairment Other Serious 2/7/2007 72 Male 126 lb 1/28/2008 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 1/16/2008 77 Female 117 lb 1/30/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 2/7/2007 72 Male 126 lb 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 77 Female 2/1/2008 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 2/7/2007 72 Male 126 lb 2/1/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 12/5/2005 33 Female 1/10/2008 Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 11/23/2007 75 Female 139 lb 2/6/2008 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 1/30/2008 66 Female 2/7/2008 Physician Japan
Primary
Concomitant
Palpitations Hospitalization 10/19/2007 Male 152 lb 2/3/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/28/2007 Male 127 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/24/2007 66 Female 86 lb 2/11/2008 Consumer Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 12/5/2005 33 Female 2/12/2008 Japan
Primary
Concomitant
Urine Output Decreased Hospitalization 1/16/2008 77 Female 117 lb 2/20/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 77 Female 2/26/2008 Other Health Professional Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 2/1/2008 Female 84 lb 2/29/2008 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 1/23/2008 Female 84 lb 3/17/2008 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 1/23/2008 Female 84 lb 3/20/2008 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/27/2007 56 Female 3/19/2008 Physician Japan
Primary
Concomitant
Wound Complication Hospitalization 3/1/2008 51 Male 141 lb 3/28/2008 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 2/7/2007 72 Male 126 lb 4/1/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/7/2007 Male 125 lb 3/26/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 46 Male 143 lb 4/16/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/17/2007 Male 143 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/24/2007 66 Female 99 lb 5/5/2008 Consumer Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 5/16/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/31/2008 Male 114 lb 5/21/2008 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/17/2007 Male 152 lb 5/27/2008 Physician Japan
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2006 Male 112 lb 5/30/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Ovarian Cancer Hospitalization Female 134 lb 6/2/2008 Physician Japan
Primary
Secondary
Concomitant
Generalised Erythema Hospitalization 2/9/2008 Female 117 lb 6/3/2008 Physician Japan
Primary
Secondary
Neurilemmoma Hospitalization 4/30/2008 Male 130 lb 6/12/2008 Physician Japan
Primary
Concomitant
Neurilemmoma Hospitalization 4/30/2008 Male 130 lb 6/17/2008 Physician Japan
Primary
Concomitant
Speech Disorder Hospitalization 12/27/2007 72 Female 6/17/2008 Physician Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 6/18/2008 Physician Japan
Primary
Concomitant
Speech Disorder Hospitalization 12/27/2007 72 Female 6/23/2008 Physician Japan
Primary
Concomitant
Neurilemmoma Hospitalization 9/25/2006 Male 130 lb 6/25/2008 Physician Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 3/25/2008 75 Female 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5/28/2008 69 Male 134 lb 6/30/2008 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/7/2007 Male 143 lb 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/17/2007 46 Male 143 lb 7/7/2008 Consumer United States
Primary
Secondary
Concomitant
Malaise Hospitalization 6/6/2008 37 Female 7/9/2008 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/25/2008 59 Male 7/9/2008 Physician Japan
Primary
Concomitant
Vertebral Artery Occlusion Hospitalization 5/28/2008 Female 86 lb 7/14/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/23/2008 Male 114 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 1/16/2008 77 Female 117 lb 7/16/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/25/2008 59 Male 7/17/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Life Threatening 11/15/2007 78 Female 108 lb 7/25/2008 Physician Japan
Primary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2006 Male 112 lb 7/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/18/2008 77 Female 7/29/2008 Pharmacist Japan
Primary
Concomitant
Renal Disorder Other Serious 6/25/2008 59 Male 7/31/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 6/5/2008 37 Female 8/7/2008 Physician Japan
Primary
Concomitant
Vitamin D Deficiency Other Serious 4/1/2006 Male 112 lb 8/7/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 7/25/2008 52 Female 106 lb 8/22/2008 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/5/2007 46 Male 143 lb 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/17/2008 63 Male 179 lb 8/29/2008 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 8/22/2008 57 Female 8/29/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 10/17/2007 Male 152 lb 8/29/2008 Physician Japan
Primary
Secondary
Concomitant
Face Oedema Other Serious 7/28/2008 25 Female 9/4/2008 Pharmacist Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 8/6/2008 71 Female 9/4/2008 Physician Japan
Primary
Secondary
Concomitant
Ovarian Cancer Recurrent Hospitalization 2/1/2007 Female 134 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/31/2008 Male 164 lb 9/5/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/24/2008 Male 9/11/2008 Physician Japan
Primary
Concomitant

Drug Data