Cyanocobalamin combined with Digoxin

Reports:

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Reaction	Outcome	Event Date	Age	Sex	Weight	Reported	Reporter	Country	Treatment
									Role	Name
Hepatic Function Abnormal	Hospitalization	12/19/2005	71	Male	141 lb	2/17/2006	Physician	Japan	Primary Secondary Concomitant
Hepatic Function Abnormal	Hospitalization	12/19/2005	71	Male	141 lb	2/24/2006	Physician	Japan	Primary Secondary Concomitant
Transient Ischaemic Attack	Hospitalization	1/1/2000	54	Male	229 lb	3/6/2006	Physician	United States	Primary Concomitant
Visual Acuity Reduced	Other Serious		79	Male	176 lb	3/7/2006		United States	Primary Secondary Concomitant
Sclerosing Encapsulating Peritonitis	Other Serious	4/2/2005	56	Male	125 lb	3/21/2006	Physician	Japan	Primary Secondary Concomitant
Treatment Noncompliance	Hospitalization	1/1/2000	54	Male	229 lb	3/31/2006	Physician	United States	Primary Concomitant
Therapy Non-responder	Other Serious		79	Male	176 lb	4/5/2006		United States	Primary Secondary Concomitant
Transient Ischaemic Attack	Hospitalization	1/1/2000	54	Male	229 lb	4/19/2006	Physician	United States	Primary Concomitant
Pulmonary Toxicity	Required Intervention	4/26/2005	72	Male	175 lb	4/20/2006	Pharmacist	United States	Primary Concomitant
Melaena	Hospitalization	1/25/2006	84	Male	174 lb	5/20/2006	Pharmacist	United States	Primary Secondary Concomitant
Mental Status Changes	Hospitalization	4/17/2006		Male		7/18/2006	Pharmacist	United States	Primary Concomitant
Weight Decreased	Hospitalization	1/1/2005	65	Female		8/14/2006		United States	Primary Secondary Concomitant
Therapy Non-responder	Other Serious		79	Male	176 lb	8/31/2006		United States	Primary Secondary Concomitant
Sclerosing Encapsulating Peritonitis	Other Serious	4/2/2005	56	Male	125 lb	11/21/2006	Physician	Japan	Primary Secondary Concomitant
Ventricular Tachycardia	Hospitalization	1/1/2005	65	Female		12/22/2006		United States	Primary Secondary Concomitant
Presyncope	Hospitalization	7/5/2006	68	Male	196 lb	10/21/2006	Pharmacist	United States	Primary Secondary Concomitant
Fatigue	Hospitalization	1/17/2007	70	Female	159 lb	3/19/2007	Consumer	United States	Primary Secondary Concomitant
Fatigue	Hospitalization	1/17/2007	70	Female	159 lb	4/5/2007	Consumer	United States	Primary Secondary Concomitant
Snoring	Life Threatening	3/25/2007	70	Female		4/23/2007	Physician	Japan	Primary Concomitant
Thrombocythaemia	Other Serious	10/30/2006	88	Female	110 lb	6/11/2007	Other Health Professional	Portugal	Primary Concomitant
White Blood Cell Count Increased	Life Threatening	3/25/2007	70	Female		6/21/2007	Physician	Japan	Primary Concomitant
Drug Interaction	Other Serious		73	Male		8/16/2007		Sweden	Primary Concomitant Interacting
International Normalised Ratio Increased	Other Serious	11/14/2007	88	Male	143 lb	11/27/2007	Consumer	United Kingdom	Primary Secondary Concomitant
Hepatitis	Other Serious	2/1/2007		Male		11/30/2007		Canada	Primary Concomitant
Retinal Exudates	Other Serious	9/1/2007	43	Female	97 lb	11/30/2007	Pharmacist	United States	Primary Concomitant
International Normalised Ratio Increased	Other Serious	11/14/2007				12/5/2007	Other Health Professional	United Kingdom	Primary Secondary Concomitant
International Normalised Ratio Increased	Life Threatening	11/14/2007	88	Male	143 lb	11/30/2007		United Kingdom	Primary Secondary Concomitant
Sclerosing Encapsulating Peritonitis	Death	2/1/2001	56	Male	123 lb	12/12/2007		Japan	Primary Secondary Concomitant
Nephrolithiasis	Hospitalization	8/6/2007		Male	145 lb	12/14/2007	Physician	United States	Primary Concomitant
International Normalised Ratio Increased	Other Serious	11/14/2007	88	Male	143 lb	12/20/2007			Primary Secondary Concomitant
Right Ventricular Failure	Other Serious	10/1/2007	70	Female	139 lb	2/1/2008	Physician	United States	Primary Secondary Concomitant
Vomiting	Hospitalization	8/12/2007		Female	91 lb	3/31/2008	Physician	Japan	Primary Secondary Concomitant
Renal Failure	Hospitalization	1/7/2008	83	Male		4/2/2008		Sweden	Primary Concomitant
Vomiting	Hospitalization	8/12/2007		Female	91 lb	4/16/2008	Physician	Japan	Primary Secondary Concomitant
Vomiting	Hospitalization	8/12/2007		Female	91 lb	4/28/2008	Physician	Japan	Primary Secondary Concomitant
Right Ventricular Failure	Other Serious	10/1/2007	70	Female	139 lb	5/23/2008	Physician	United States	Primary Secondary Concomitant
Psoriasis		1/1/2008		Female	232 lb	6/13/2008	Physician	United States	Primary Concomitant
Orthostatic Hypotension	Hospitalization	3/14/2008	73	Male		9/29/2008	Other Health Professional	France	Primary Concomitant
Somnolence	Other Serious	9/6/2008		Female		11/7/2008	Physician	Japan	Primary Concomitant Interacting
Somnolence	Other Serious	8/29/2008		Female		11/19/2008	Physician	Japan	Primary Concomitant Interacting
Lid Lag	Other Serious	8/31/2008	74	Male		11/20/2008	Pharmacist	Japan	Primary Concomitant
Hiccups	Hospitalization	10/25/2008	80	Male		12/19/2008	Other Health Professional	Sweden	Primary Secondary Concomitant
Hiccups	Hospitalization	10/25/2008	80	Male		12/31/2008	Other Health Professional	Sweden	Primary Secondary Concomitant
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	2/5/2009	Physician	Japan	Primary Concomitant
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	2/19/2009	Physician	Japan	Primary Secondary Concomitant
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	2/23/2009	Physician	Japan	Primary Secondary Concomitant
Myocardial Infarction	Other Serious	6/11/2006	65	Male	209 lb	2/23/2009	Physician	Germany	Primary Concomitant Interacting
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	3/5/2009	Physician	Japan	Primary Secondary Concomitant
Sepsis	Death		77	Male		4/15/2009	Consumer	United States	Primary Secondary
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	4/15/2009	Physician	Japan	Primary Secondary Concomitant
Sepsis	Death		75	Male		4/21/2009	Consumer	United States	Primary Concomitant
Sepsis	Other Serious			Male		4/21/2009	Consumer	United States	Primary Concomitant
Sepsis	Death			Male		4/23/2009	Physician	United States	Primary Secondary
Sepsis	Hospitalization			Male		4/23/2009	Physician	United States	Primary Secondary Concomitant
Sepsis	Death		75	Male		4/21/2009		United States	Primary Concomitant
Sepsis	Other Serious			Male		4/30/2009	Consumer	United States	Primary Concomitant
Sepsis	Death			Male	304 lb	5/5/2009	Consumer		Primary Secondary Concomitant
Weight Decreased	Required Intervention	8/11/2008		Male	172 lb	4/2/2009	Consumer	United States	Primary Concomitant
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	5/13/2009	Physician	Japan	Primary Secondary Concomitant
Upper Gastrointestinal Haemorrhage	Other Serious		86	Female		5/7/2009	Consumer	United States	Primary Concomitant
Sepsis	Death		75	Male		5/19/2009	Consumer	United States	Primary Concomitant
Sepsis	Death		77	Male		5/29/2009	Consumer	United States	Primary Secondary
Sepsis	Death	12/18/2006		Male		6/29/2009	Physician	United States	Primary Secondary
Sepsis	Death		75	Male		7/1/2009	Consumer	United States	Primary Secondary
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	7/2/2009	Physician	Japan	Primary Secondary Concomitant
Vomiting	Hospitalization		72	Female		7/1/2009	Lawyer	United States	Primary Concomitant
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	7/10/2009	Physician	Japan	Primary Secondary Concomitant
Weight Decreased	Hospitalization		74	Male		7/15/2009	Lawyer	United States	Primary Concomitant
Restrictive Cardiomyopathy	Other Serious	7/17/2008		Female	121 lb	7/22/2009	Physician	Japan	Primary Secondary Concomitant
Vomiting	Hospitalization		72	Female		7/19/2009		United States	Primary Concomitant
Vomiting	Hospitalization		72	Female		7/22/2009	Lawyer	United States	Primary Concomitant
Vomiting	Hospitalization	12/6/2007	72	Female		8/5/2009		United States	Primary Concomitant
Vomiting	Hospitalization	12/6/2007	72	Female		8/14/2009	Lawyer	United States	Primary Concomitant
Weight Decreased	Hospitalization	4/26/2008	85	Female		8/26/2009		United States	Primary Concomitant
Unevaluable Event	Hospitalization		90	Female		9/2/2009		United States	Primary Concomitant
Renal Failure	Hospitalization	8/23/2009	72	Female	137 lb	9/5/2009	Pharmacist	United States	Primary Secondary Concomitant
Surgery	Hospitalization		90	Female		9/4/2009	Lawyer	United States	Primary Concomitant
Urinary Tract Infection	Hospitalization		79	Female		9/8/2009		United States	Primary Concomitant
Urinary Tract Infection	Hospitalization		79	Female		9/14/2009		United States	Primary Concomitant
Vomiting	Hospitalization	5/2/2008	81	Female	144 lb	9/16/2009		United States	Primary Concomitant
Urinary Tract Infection	Hospitalization		79	Female		10/9/2009		United States	Primary Concomitant
Ventricular Tachycardia	Hospitalization	7/1/2009		Male	214 lb	10/28/2009	Physician	United States	Primary Concomitant
Subdural Haematoma	Hospitalization	9/29/2009	87	Male		10/28/2009	Other Health Professional	Germany	Primary Concomitant
Urinary Tract Infection	Hospitalization		90	Female		10/26/2009		United States	Primary Concomitant
Ventricular Tachycardia	Hospitalization		90	Female		11/18/2009		United States	Primary Concomitant
Unevaluable Event	Hospitalization		67	Female		11/24/2009		United States	Primary Concomitant
Weight Decreased	Hospitalization	4/26/2008	85	Female		12/1/2009		United States	Primary Concomitant
Thrombocytopenia	Hospitalization		67	Female		12/1/2009	Lawyer	United States	Primary Concomitant
Thrombocytopenia	Hospitalization		67	Female		12/11/2009		United States	Primary Concomitant
Vascular Rupture	Hospitalization		70	Female		1/7/2010		United States	Primary Concomitant
Thrombocytopenia	Hospitalization		67	Female		1/13/2010		United States	Primary Concomitant
Weight Increased	Hospitalization		65	Male		1/22/2010	Lawyer	United States	Primary Concomitant
Weight Decreased	Other Serious	10/1/2009	80	Male		3/6/2010	Other Health Professional	Japan	Primary Secondary Concomitant
Thrombosis	Other Serious	4/1/2010	76	Female		5/19/2010	Physician	United States	Primary Concomitant
Interstitial Lung Disease	Hospitalization	3/7/2010	69	Male		6/30/2010	Physician	Japan	Primary Concomitant
Macular Oedema	Disability	5/7/2010	85	Female		6/30/2010	Physician	Japan	Primary Secondary Concomitant
Vomiting	Other Serious		66	Female	242 lb	7/19/2010	Other Health Professional	Canada	Primary Secondary Concomitant
Ventricular Tachycardia	Hospitalization	4/7/2010	88	Female	130 lb	7/28/2010	Pharmacist	United States	Primary Secondary Concomitant
Loss Of Consciousness	Other Serious	1/1/2010	74	Male		8/11/2010	Consumer	United States	Primary Secondary Concomitant
Ventricular Tachycardia	Hospitalization	4/7/2010	88	Female	130 lb	8/18/2010	Pharmacist	United States	Primary Secondary Concomitant
Ventricular Tachycardia	Hospitalization	4/7/2010	88	Female	130 lb	9/8/2010	Pharmacist	United States	Primary Secondary Concomitant
Syncope	Hospitalization	9/10/2009	75	Female	131 lb	9/17/2010	Physician	United States	Primary Secondary Concomitant
Ventricular Tachycardia	Other Serious	4/7/2010		Female	130 lb	9/21/2010	Pharmacist	United States	Primary Secondary Concomitant
Weight Decreased	Other Serious	12/1/2003	79	Male	159 lb	9/29/2010		United States	Primary Secondary Concomitant
Throat Tightness			61	Female	158 lb	10/13/2010	Consumer	United States	Primary Concomitant
Ventricular Tachycardia	Other Serious	4/7/2010		Female	130 lb	10/14/2010	Pharmacist	United States	Primary Secondary Concomitant
Ventricular Tachycardia	Hospitalization	4/7/2010	88	Female	130 lb	10/29/2010	Pharmacist	United States	Primary Secondary Concomitant
Varicose Vein	Other Serious	1/1/2009				11/4/2010	Physician	Germany	Primary Secondary Concomitant
Superinfection	Hospitalization	5/11/2010	78	Male	123 lb	5/25/2010	Pharmacist	United States	Primary Secondary Concomitant
Stress Urinary Incontinence	Hospitalization	4/26/2008	85	Female	100 lb	1/13/2011	Lawyer	United States	Primary Concomitant
Cold Sweat	Hospitalization	7/31/2010	62	Male	141 lb	1/25/2011	Other Health Professional	Portugal	Primary Concomitant
Right Ventricular Failure	Other Serious	1/1/2009	71	Female	207 lb	2/8/2011	Consumer	Germany	Primary Secondary Concomitant
Scoliosis	Disability	12/1/2003	79	Male	159 lb	3/8/2011	Other Health Professional	United States	Primary Secondary Concomitant
Cardioactive Drug Level Increased	Other Serious	1/1/2009	71	Female	207 lb	3/21/2011	Consumer	Germany	Primary Secondary Concomitant
Asthenia	Hospitalization	2/28/2011	71	Male	194 lb	4/6/2011	Physician	United States	Primary Secondary Concomitant
Death	Death		79	Female		4/26/2011	Other Health Professional	United States	Primary Concomitant
International Normalised Ratio Increased	Other Serious		75	Male		5/3/2011	Other Health Professional	United Kingdom	Primary Concomitant Interacting
Renal Failure Chronic	Hospitalization			Female		5/16/2011	Physician	United States	Primary Concomitant
Clostridium Difficile Colitis	Hospitalization	4/7/2011	77	Female	130 lb	6/10/2011	Physician	United States	Primary Concomitant
Hyperkalaemia	Hospitalization	5/18/2011	82	Female		6/16/2011	Other Health Professional	Japan	Primary Concomitant Interacting
Hepatic Enzyme Increased	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Muscle Twitching	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Hepatic Enzyme Increased	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Neutralising Antibodies Positive	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Pain	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Gastritis Erosive	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Gastritis Erosive	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Aplasia Pure Red Cell	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Hepatic Enzyme Increased	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Fatigue	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Aplasia Pure Red Cell	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Cystitis	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Fatigue	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Neutralising Antibodies Positive	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Gastritis Erosive	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Haemorrhoids	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Fatigue	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Hepatic Enzyme Increased	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Gastritis Erosive	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Anal Fissure	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Hepatic Enzyme Increased	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Haemorrhoids	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Fatigue	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Cardioactive Drug Level Increased	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Haemorrhoids	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Pain	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Varicose Vein	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Gastritis Erosive	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary Concomitant
Varicose Vein	Hospitalization	1/1/2009	71	Female	207 lb	6/21/2011	Other Health Professional	Germany	Primary Secondary Concomitant
Pain	Other Serious	1/1/2009	71	Female	207 lb	6/21/2011	Physician	Germany	Primary Secondary