Crestor combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Death 1/1/2004 77 Male 192 lb 2/7/2006 Physician Canada
Primary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Myocardial Infarction Other Serious 2/1/2004 61 Male 198 lb 2/17/2006 Lawyer United States
Primary
Concomitant
Injury Hospitalization 9/11/2003 66 Male 218 lb 3/9/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/11/2003 66 Male 218 lb 3/17/2006 Physician United States
Primary
Concomitant
Skin Reaction 1/1/2005 Male 1/20/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Vomiting Other Serious 2/21/2005 73 Male 5/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 64 Female 1/16/2007 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 6/1/2006 62 Male 170 lb 5/14/2007 Consumer Netherlands
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/29/2006 54 Female 277 lb 4/26/2007 United States
Primary
Concomitant
Rash Other Serious 1/1/2007 Female 137 lb 11/20/2007 Other Health Professional Canada
Primary
Concomitant
Myalgia Other Serious 10/9/2007 59 Female 11/28/2007 Japan
Primary
Secondary
Concomitant
Protein Urine Present Other Serious 6/1/2006 56 Male 3/17/2008
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/1/2006 56 Male 3/20/2008 Physician Canada
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 6/1/2006 56 Male 4/14/2008 Physician United States
Primary
Secondary
Concomitant
Nephritis Allergic Other Serious 6/1/2006 56 Male 7/15/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/8/2007 Female 123 lb 7/16/2008 Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/8/2007 Female 123 lb 7/28/2008 Japan
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/13/2008 Female 7/29/2008 Other Health Professional Ireland
Primary
Concomitant
Myocardial Infarction Other Serious 7/13/2008 Female 8/1/2008 Other Health Professional Ireland
Primary
Concomitant
Myocardial Infarction Death 56 Female 8/26/2008 Consumer Ireland
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 5/23/2008 Female 115 lb 10/20/2008 Physician United States
Primary
Concomitant
Influenza Like Illness Hospitalization 1/1/2008 Male 10/20/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2008 65 Female 182 lb 10/24/2008 United States
Primary
Concomitant
Renal Failure Other Serious 3/10/2008 4/8/2009 Other Health Professional Netherlands
Primary
Concomitant
Renal Failure Other Serious 3/10/2008 Female 287 lb 4/20/2009 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Other Serious 4/24/2002 42 Female 258 lb 5/20/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2004 48 Male 220 lb 6/2/2009 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 4/17/2009 64 Female 119 lb 6/3/2009 Physician Canada
Primary
Concomitant
Myocardial Ischaemia Other Serious 2/17/2009 Male 273 lb 6/4/2009 United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/21/2003 36 Female 188 lb 6/5/2009 United States
Primary
Concomitant
Musculoskeletal Chest Pain 10/16/2008 Female 6/11/2009 United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration 5/2/2009 Male 265 lb 6/12/2009 United States
Primary
Concomitant
Paralysis Hospitalization 5/1/2006 41 Male 365 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 53 Female 279 lb 6/15/2009 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 3/1/2009 Male 197 lb 6/15/2009 Consumer United States
Primary
Concomitant
Weight Decreased 6/15/2009 Physician United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 5/29/2009 Male 240 lb 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/26/2009 Australia
Primary
Concomitant
Visual Impairment Other Serious 12/23/2008 60 7/13/2009 Australia
Primary
Concomitant
Wheezing Other Serious 11/1/2008 49 Female 150 lb 7/28/2009 Physician United States
Primary
Concomitant
Wound Other Serious 7/28/2009 69 Male 161 lb 8/6/2009 Consumer Brazil
Primary
Concomitant
Erectile Dysfunction 1/1/2008 49 8/11/2009 Physician Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2008 Female 207 lb 9/29/2009 Consumer Brazil
Primary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 4/27/2009 83 Male 353 lb 9/30/2009 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Hiccups 8/24/2009 73 Male 216 lb 10/1/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Male 206 lb 10/1/2009 Consumer United States
Primary
Secondary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Diverticulitis Hospitalization 4/1/2009 55 Male 220 lb 10/9/2009 Other Health Professional United States
Primary
Concomitant
Headache 7/6/2009 66 Female 215 lb 10/12/2009 Consumer United States
Primary
Concomitant
Vascular Rupture Other Serious 85 Female 10/12/2009
Primary
Concomitant
Stress Other Serious 4/1/2008 Female 141 lb 10/12/2009 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious 5/4/2009 Female 167 lb 10/13/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 206 lb 10/14/2009 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 9/1/2009 Female 10/7/2009 Consumer United States
Primary
Concomitant
Pain Hospitalization 1/1/2007 Male 365 lb 10/6/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/9/2006 54 Male 263 lb 10/15/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Life Threatening Male 204 lb 10/15/2009 Physician Canada
Primary
Concomitant
Foot Deformity Other Serious Female 190 lb 10/16/2009 Other Health Professional Canada
Primary
Concomitant
Tachyarrhythmia Hospitalization 6/27/2009 Female 151 lb 10/19/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 206 lb 11/30/2009 Consumer United States
Primary
Concomitant
Road Traffic Accident Hospitalization Male 240 lb 1/7/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 3/17/2009 68 Male 1/4/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 50 Male 1/4/2010 Consumer United States
Primary
Concomitant
Gastrointestinal Carcinoma Death 10/1/2009 65 Female 198 lb 1/11/2010 Physician Netherlands
Primary
Concomitant
Diarrhoea Other Serious Male 1/12/2010 Consumer Brazil
Primary
Concomitant
Arthropathy Hospitalization 10/26/2009 Male 1/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/1/2009 67 Male 170 lb 1/15/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 1/22/2010 Female 200 lb 3/3/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 Male 94 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 Male 94 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Bypass Hospitalization Female 127 lb 3/3/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 70 Male 95 lb 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious 1/19/2010 Male 183 lb 3/10/2010 Consumer Japan
Primary
Concomitant
Skin Hypertrophy Other Serious 5/1/2009 44 Female 245 lb 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 12/1/2007 Male 200 lb 3/17/2010 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 3/18/2009 76 Male 196 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 9/30/2009 Female 3/18/2010 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 12/7/2009 70 Male 95 lb 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Mass Other Serious 1/1/2007 Female 211 lb 3/18/2010 Physician United States
Primary
Concomitant
Pruritus Other Serious 3/12/2010 Male 3/26/2010 United States
Primary
Concomitant
Thyroid Disorder Other Serious Male 4/21/2010 Other Health Professional United States
Primary
Secondary
Thyroid Disorder Other Serious Male 4/22/2010 Other Health Professional United States
Primary
Secondary
Thyroid Disorder Other Serious Male 5/10/2010 Other Health Professional United States
Primary
Secondary
Thyroid Disorder Other Serious Male 5/10/2010 Other Health Professional United States
Primary
Secondary
Skin Lesion Hospitalization 10/15/2009 65 Male 5/12/2010 Physician France
Primary
Secondary
Product Substitution Issue Other Serious 1/1/2010 Female 5/10/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2009 60 Female 139 lb 5/17/2010 Consumer Brazil
Primary
Concomitant
Ulcerative Keratitis Other Serious 4/12/2010 54 Female 184 lb 5/21/2010 Other Health Professional Canada
Primary
Concomitant
Fatigue Other Serious 8/1/2009 89 Male 5/21/2010 Physician Canada
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Other Serious 3/11/2010 50 Male 5/27/2010 Physician Canada
Primary
Concomitant
Liver Injury Hospitalization 1/13/2010 54 Male 183 lb 5/27/2010 Physician Germany
Primary
Secondary
Concomitant
Liver Injury Other Serious 1/13/2010 54 Male 183 lb 5/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/2/2010 69 Female 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/8/2010 62 Female 223 lb 5/28/2010 Physician United States
Primary
Concomitant
Pancreatic Disorder Other Serious 1/1/2010 50 Male 6/8/2010 Physician United States
Primary
Concomitant
Sopor Other Serious 3/4/2010 77 Female 6/29/2010 Physician Italy
Primary
Secondary
Concomitant
Erectile Dysfunction 1/1/2008 57 Male 155 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Urticaria 1/1/2009 Female 225 lb 7/27/2010 Consumer United States
Primary
Concomitant
Rash 8/22/2008 64 Female 301 lb 7/29/2010 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 5/20/2006 67 Female 146 lb 7/30/2010 Consumer Brazil
Primary
Concomitant
Osteoarthritis Other Serious 5/20/2006 67 Female 146 lb 9/1/2010 Consumer Brazil
Primary
Concomitant
Weight Decreased Hospitalization Male 250 lb 9/10/2010 Physician United States
Primary
Concomitant
Weight Decreased 1/1/2009 69 Male 9/10/2010 Consumer
Primary
Concomitant
Thrombocytopenia Hospitalization 7/24/2010 70 Female 216 lb 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms 1/1/2008 Male 210 lb 10/26/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/1/2010 70 Female 216 lb 10/27/2010 Physician United States
Primary
Secondary
Concomitant
Retinal Vascular Disorder Other Serious 1/1/2009 69 Male 185 lb 11/2/2010 Consumer Brazil
Primary
Concomitant
Interacting
Pain In Extremity Other Serious 5/20/2006 67 Female 146 lb 12/1/2010 Consumer Brazil
Primary
Concomitant
Swelling Face Other Serious 11/1/2010 Female 12/6/2010 Physician Brazil
Primary
Concomitant
Osteoarthritis Hospitalization 69 Male 185 lb 12/8/2010 Physician Brazil
Primary
Concomitant
Skin Cancer Disability 1/1/2009 72 Female 209 lb 12/13/2010 Consumer Brazil
Primary
Secondary
Concomitant
Nausea 12/16/2009 54 Female 197 lb 12/14/2010 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 11/29/2010 70 Male 141 lb 12/14/2010 Pharmacist Switzerland
Primary
Secondary
Concomitant
Osteoporosis Other Serious 5/20/2006 67 Female 146 lb 12/16/2010 Consumer Brazil
Primary
Concomitant
H1n1 Influenza Other Serious 1/1/2007 61 Female 219 lb 1/3/2011 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 11/29/2010 70 Male 141 lb 1/6/2011 Pharmacist Switzerland
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/1/2009 50 Male 179 lb 1/10/2011 Consumer Brazil
Primary
Concomitant
Diabetes Mellitus Disability 1/1/2009 72 Female 209 lb 1/31/2011 Physician Brazil
Primary
Secondary
Concomitant
Headache Hospitalization 12/1/2010 67 Male 2/11/2011 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 8/25/2010 83 Female 2/14/2011 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2007 66 Female 136 lb 2/24/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Genital Tract Inflammation Other Serious 4/24/2002 42 Female 258 lb 3/2/2011 Other Health Professional United States
Primary
Concomitant
Back Pain Other Serious 9/22/2010 50 Female 3/21/2011 Physician Canada
Primary
Concomitant
Rash Macular Hospitalization 9/1/2010 61 Female 3/25/2011 Consumer Canada
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2010 61 Female 4/1/2011 Consumer Canada
Primary
Concomitant
Blood Cholesterol Increased Hospitalization 8/26/2010 44 Male 185 lb 5/2/2011 United States
Primary
Secondary
Concomitant
Interacting
Flatulence Other Serious 62 Male 209 lb 6/9/2011 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/20/2007 71 Female 150 lb 6/4/2011 Consumer Canada
Primary
Concomitant
Arterial Bypass Operation Hospitalization 3/1/2011 63 Female 6/24/2011 Consumer Brazil
Primary
Secondary
Concomitant
Osteoporosis Other Serious 5/20/2006 67 Female 143 lb 6/28/2011 Consumer Brazil
Primary
Concomitant
Atrophy Other Serious 7/18/2010 64 Female 7/5/2011 Physician Canada
Primary
Concomitant
Blood Urine Present Hospitalization 6/1/2006 67 Female 7/6/2011 Japan
Primary
Concomitant
Urine Cytology Abnormal Hospitalization 6/9/2006 62 Female 7/18/2011 Other Health Professional Japan
Primary
Concomitant
Blood Glucose Increased Life Threatening 5/1/2010 57 Female 174 lb 8/10/2011 Consumer United States
Primary
Secondary
Concomitant
Oedema Life Threatening 4/22/2009 64 Male 8/11/2011 Japan
Primary
Concomitant
Weight Increased Disability 11/15/2010 54 Male 8/12/2011 Physician Denmark
Primary
Secondary
Goitre Hospitalization 1/1/2008 61 Female 168 lb 8/22/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant
Laboratory Test Abnormal Other Serious Male 8/24/2011 Consumer Brazil
Primary
Concomitant
Pain Hospitalization 8/1/2011 63 Male 325 lb 8/24/2011 Consumer United States
Primary
Concomitant
Prostate Cancer Other Serious Male 183 lb 8/29/2011 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/1/2010 57 Female 278 lb 8/29/2011 Physician United States
Primary
Concomitant
Cheyne-stokes Respiration Death 9/15/2010 75 Female 8/29/2011 Canada
Primary
Secondary
Concomitant
Carotid Artery Thrombosis Other Serious 53 184 lb 8/29/2011 United States
Primary
Concomitant
Impaired Work Ability Disability 11/15/2010 54 Male 8/26/2011 Physician Denmark
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/9/2006 62 Female 8/31/2011 Other Health Professional Japan
Primary
Concomitant

Drug Data