Crestor combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stevens-johnson Syndrome Hospitalization 12/1/2005 70 Female 126 lb 1/19/2006 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/1/2005 70 Female 126 lb 1/30/2006 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/1/2005 70 Female 126 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 36 Male 6/5/2006 Physician Japan
Primary
Secondary
Acute Myocardial Infarction Death 5/26/2006 36 Male 7/7/2006 Physician Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 7/5/2005 69 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 51 Female 198 lb 9/12/2006 United States
Primary
Concomitant
Visual Disturbance Hospitalization Female 1/4/2007 Consumer United States
Primary
Concomitant
Low Density Lipoprotein Decreased Other Serious 62 Male 11/28/2006 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 84 Female 181 lb 5/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 5/18/2007 Consumer Canada
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/22/2006 50 Male 6/25/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 80 Female 7/26/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 7/26/2007 Physician Canada
Primary
Concomitant
Swelling Face Other Serious 6/1/2007 57 Male 7/30/2007 Pharmacist Canada
Primary
Concomitant
Swelling Face Other Serious 6/1/2007 57 Male 8/3/2007 Pharmacist Canada
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/13/2007 80 Female 8/14/2007 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 11/1/2007 Female 295 lb 1/29/2008 Physician United States
Primary
Concomitant
Interacting
Renal Mass Hospitalization 2/15/2008 Male 228 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/7/2007 74 Male 196 lb 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Skin Chapped 1/1/2008 79 Male 7/25/2008 Consumer United States
Primary
Concomitant
No Adverse Event 2/15/2008 Male 228 lb 8/11/2008 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2006 79 Male 8/12/2008 United States
Primary
Concomitant
Product Quality Issue Other Serious 7/1/2007 56 Male 190 lb 11/25/2008 Consumer United States
Primary
Concomitant
Flatulence 4/1/2008 78 Female 155 lb 12/17/2008 Consumer United States
Primary
Concomitant
Renal Function Test Abnormal Other Serious 10/5/2008 55 Male 12/19/2008 Consumer United States
Primary
Concomitant
Tremor Hospitalization 10/28/2008 75 Female 156 lb 12/22/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2007 57 Male 248 lb 12/22/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 11/12/2008 81 Female 175 lb 12/30/2008 Consumer United States
Primary
Concomitant
Dyspepsia 2/1/2008 69 Female 265 lb 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 12/1/2008 75 Male 165 lb 1/9/2009 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/1998 78 Male 137 lb 1/14/2009 Consumer United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 1/1/2000 Male 2/4/2009 Other Health Professional United States
Primary
Concomitant
Sensation Of Pressure Hospitalization 6/1/2008 64 Female 153 lb 3/13/2009 Consumer United States
Primary
Concomitant
Syncope Hospitalization 3/3/2008 58 Male 3/30/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 7/1/2008 59 Male 7/23/2009 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious 10/1/2008 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 3/10/1998 54 Male 209 lb 9/23/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 10/18/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 10/26/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 11/16/2009 United States
Primary
Concomitant
Amnesia Other Serious Female 12/22/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 1/21/2010 United States
Primary
Concomitant
Haemorrhoids Other Serious 12/22/2009 73 Female 165 lb 4/7/2010 Consumer United States
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 12/22/2009 73 Female 165 lb 4/9/2010 Consumer United States
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 12/22/2009 73 Female 165 lb 4/13/2010 Consumer United States
Primary
Secondary
Concomitant
Sensitivity Of Teeth 9/1/2006 50 Female 260 lb 7/8/2010 Consumer United States
Primary
Concomitant
Nightmare 1/1/2007 80 Female 120 lb 7/15/2010 Consumer United States
Primary
Concomitant
Malaise Other Serious 9/1/2007 67 Male 7/15/2010 Other Health Professional United States
Primary
Concomitant
Muscle Spasms 10/6/2009 64 Female 182 lb 8/27/2010 United States
Primary
Concomitant
Flushing 1/1/2007 55 Male 218 lb 8/29/2010 United States
Primary
Concomitant
Off Label Use 1/1/2010 80 Female 9/10/2010 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/8/2010 82 Female 9/29/2010 Physician Italy
Primary
Concomitant
Drug Interaction Other Serious 6/30/2010 56 Male 184 lb 9/28/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Infection Other Serious 10/1/2010 65 Male 220 lb 11/29/2010 Consumer United States
Primary
Concomitant
Renal Failure Female 194 lb 11/22/2010 United States
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 9/1/2010 77 Female 1/14/2011 Physician United States
Primary
Concomitant
Cyanosis Death 2/1/2008 67 Male 192 lb 3/4/2011 Other Health Professional United States
Primary
Concomitant
Cardiac Disorder Hospitalization 64 Female 193 lb 3/11/2011 Physician United States
Primary
Concomitant
Suffocation Feeling Required Intervention 10/1/2010 75 Male 3/3/2011 Pharmacist Italy
Primary
Concomitant
Haemorrhage Hospitalization 87 Male 4/7/2011 United States
Primary
Concomitant
Vomiting Hospitalization 2/12/2007 68 Male 175 lb 4/29/2011 Lawyer United States
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 3/25/2011 59 Female 160 lb 6/10/2011 Physician United States
Primary
Secondary
Concomitant
Groin Infection Disability 3/7/2011 58 Female 160 lb 6/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Peritoneal Haemorrhage Hospitalization 3/25/2011 59 Female 160 lb 6/22/2011 Physician United States
Primary
Secondary
Concomitant
Dizziness Other Serious 5/1/2011 88 Female 6/24/2011 Physician Japan
Primary
Concomitant
Oedema Peripheral 6/25/2011 84 Female 7/14/2011 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization 4/1/2007 64 Female 193 lb 7/19/2011 Lawyer United States
Primary
Concomitant
Tinnitus 2/1/2011 Male 7/19/2011 Consumer United States
Primary
Concomitant
Burning Sensation 7/19/2011 Female 7/25/2011 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 5/1/2011 88 Female 7/27/2011 Physician Japan
Primary
Concomitant
Flushing Male 160 lb 8/5/2011 Consumer United States
Primary
Concomitant
Urticaria Male 140 lb 8/5/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral 6/25/2011 84 Female 8/18/2011 Consumer United States
Primary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 12/5/2010 75 Male 9/6/2011 Physician Japan
Primary
Concomitant
Pain 6/25/2011 84 Female 183 lb 9/13/2011 Other Health Professional United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 4/1/2007 64 Female 193 lb 9/20/2011 Other Health Professional United States
Primary
Concomitant
Infection Other Serious 6/28/2011 78 Female 99 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 9/14/2010 75 Female 10/10/2011 Physician Japan
Primary
Concomitant
Groin Infection Other Serious 3/7/2011 58 Female 160 lb 9/29/2011 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 45 Female 181 lb 10/10/2011 Brazil
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/19/2011 43 Female 139 lb 10/10/2011 United States
Primary
Concomitant
Renal Impairment Disability 3/12/2011 69 Male 170 lb 10/10/2011 Physician Japan
Primary
Concomitant
Infectious Peritonitis Hospitalization 5/18/2009 Female 10/13/2011 Physician Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/22/2011 73 Female 10/19/2011 Physician United States
Primary
Concomitant
Hypertriglyceridaemia Other Serious 45 Female 181 lb 10/24/2011 Physician Brazil
Primary
Concomitant
Hallucination Hospitalization 10/2/2011 69 Male 165 lb 10/25/2011 Pharmacist Brazil
Primary
Concomitant
Hepatomegaly Hospitalization 12/1/2008 63 Female 181 lb 10/26/2011 Physician Brazil
Primary
Secondary
Concomitant
Tachycardia Other Serious 45 Female 181 lb 11/1/2011 Physician Brazil
Primary
Concomitant
Transient Ischaemic Attack Other Serious 45 Female 181 lb 11/3/2011 Brazil
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 45 Female 181 lb 11/3/2011 Brazil
Primary
Secondary
Concomitant
Dizziness 7/19/2011 Female 11/14/2011 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 62 Male 11/17/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization Male 192 lb 11/25/2011 Consumer United States
Primary
Concomitant
Myalgia 78 Female 108 lb 12/19/2011 United States
Primary
Concomitant
Cardiac Disorder 2/5/2010 81 Male 239 lb 12/19/2011 Other Health Professional United States
Primary
Concomitant
Clumsiness Other Serious 4/9/2011 66 Male 1/3/2012 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 10/1/2011 68 Female 1/5/2012 Pharmacist
Primary
Concomitant
Neuralgia Hospitalization 7/24/2007 73 Female 133 lb 1/17/2012 United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 61 Male 1/17/2012 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 5/1/2009 Female 119 lb 1/24/2012 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/9/2011 74 Male 152 lb 1/30/2012 Physician Japan
Primary
Concomitant
Drug Dose Omission 10/1/2010 59 Male 254 lb 1/27/2012 Consumer United States
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 9/14/2010 75 Female 1/31/2012 Physician Japan
Primary
Concomitant
Middle Insomnia Other Serious 1/1/2010 53 Female 152 lb 1/31/2012 Consumer United States
Primary
Concomitant
Migraine Other Serious 4/19/2011 43 Female 139 lb 1/31/2012 Other Health Professional United States
Primary
Concomitant
Diarrhoea Other Serious 10/1/2011 68 Female 1/25/2012 Pharmacist United States
Primary
Concomitant
Nasopharyngitis 1/9/2012 55 Male 185 lb 2/2/2012 Physician United States
Primary
Concomitant
Herpes Zoster Other Serious 1/1/2008 81 Female 137 lb 2/8/2012 Consumer Brazil
Primary
Secondary
Concomitant
Nervousness Other Serious 11/1/2010 81 Male 181 lb 2/15/2012 Consumer Brazil
Primary
Concomitant
Bile Duct Cancer Hospitalization 1/29/2012 74 Male 174 lb 2/16/2012 Physician Japan
Primary
Concomitant
Dizziness Hospitalization 1/1/2012 78 Female 2/17/2012 Consumer United States
Primary
Concomitant
Bile Duct Cancer Hospitalization 1/29/2012 74 Male 174 lb 2/24/2012 Physician Japan
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death Female 3/1/2012 Physician United States
Primary
Concomitant
Diffuse Alveolar Damage Death 8/27/2010 62 Male 132 lb 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Erythema Hospitalization Male 3/14/2012 Consumer United States
Primary
Concomitant
Epistaxis 2/1/2012 78 Male 3/22/2012 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 1/1/2008 57 Male 192 lb 3/26/2012 Consumer Brazil
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/21/2011 60 Male 95 lb 4/2/2012 Other Health Professional Japan
Primary
Concomitant
Blood Pressure Increased 78 Female 200 lb 4/17/2012 United States
Primary
Secondary
Concomitant
Chromaturia Other Serious 1/1/2012 72 Male 5/29/2012 Other Health Professional United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 5/16/2012 85 Male 199 lb 6/4/2012 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/30/2012 79 Female 6/4/2012 Physician Japan
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 5/16/2012 85 Male 199 lb 6/13/2012 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/1/2012 73 Male 192 lb 6/15/2012 Consumer Brazil
Primary
Concomitant
Vascular Graft Occlusion Other Serious 5/1/2011 67 Male 154 lb 6/29/2012 Consumer Brazil
Primary
Secondary
Concomitant
Chromaturia Other Serious 5/1/2012 72 Male 290 lb 7/5/2012 Other Health Professional United States
Primary
Concomitant
Back Pain Other Serious 5/1/2012 72 Male 290 lb 7/7/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 5/30/2012 79 Female 128 lb 7/10/2012 Physician Japan
Primary
Secondary
Concomitant
Myoclonus Hospitalization 6/20/2012 61 Male 107 lb 7/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/30/2012 79 Female 128 lb 7/27/2012 Physician Japan
Primary
Secondary
Concomitant
Haemorrhagic Disorder 8/1/2008 56 Male 8/3/2012 Consumer United States
Primary
Concomitant
Skin Plaque Other Serious 3/2006 66 Female 220 lb 12/13/2012 Other Health Professional Us
Primary
Concomitant
Renal Artery Stenosis Other Serious 7/24/2007 73 Female 133 lb 10/12/2012 Us
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 2/5/2010 82 Male 239 lb 11/2/2012 Us
Primary
Secondary
Concomitant
Vascular Graft Occlusion Hospitalization 61 Male 280 lb 9/3/2012 Consumer Us
Primary
Secondary
Concomitant
Vitamin D Deficiency Hospitalization 5/13/2012 55 Female 9/10/2012 Consumer Us
Primary
Secondary
Concomitant
Vitamin D Deficiency 67 Female 249 lb 9/12/2012 Consumer Us
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/27/2012 75 Female 119 lb 11/21/2012 Physician Jp
Primary
Concomitant
Renal Failure Other Serious Female 10/22/2012 Physician Us
Primary
Concomitant
Rhabdomyolysis Hospitalization 64 Male 11/5/2012 Us
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/16/2012 72 Male 288 lb 11/26/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Urinary Tract Infection Death 9/27/2012 75 Female 119 lb 12/7/2012 Jp
Primary
Concomitant
Pneumonia Other Serious 12/2012 83 Female 135 lb 2/11/2013 Consumer Us
Primary
Concomitant
Thyroid Disorder Other Serious 2004 52 Male 256 lb 2/11/2013 Consumer Us
Primary
Secondary
Concomitant
Thyroid Disorder Death 2004 52 Male 256 lb 2/11/2013 Consumer Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/2013 83 Female 134 lb 2/8/2013 Consumer Us
Primary
Concomitant
Vision Blurred Other Serious 1/28/2013 79 Female 103 lb 3/26/2013 Other Health Professional Us
Primary
Concomitant
Breast Pain Male 3/4/2013 Consumer Country Not Specified
Primary
Concomitant

Drug Data