Crestor combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Ineffective 2/7/2006 69 Female 181 lb 9/6/2006 Consumer United States
Primary
Concomitant
Protein Urine Required Intervention 70 Male 2/23/2006 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 5/18/2007 Consumer Canada
Primary
Concomitant
Insomnia 2/1/2007 72 Male 225 lb 4/12/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 6/22/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/1/2006 Female 125 lb 7/26/2007 Physician Canada
Primary
Concomitant
Rash Pustular Other Serious 7/20/2007 Male 215 lb 8/7/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/26/2007 Male 200 lb 8/9/2007 Consumer United States
Primary
Concomitant
Gastritis Hospitalization 4/24/2007 68 Female 135 lb 9/5/2007 Consumer United States
Primary
Concomitant
Lipase Increased Hospitalization 6/1/2007 Male 10/29/2007 Physician United States
Primary
Concomitant
Drug Ineffective 6/1/2007 84 Male 11/14/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/21/2007 54 Male 188 lb 12/5/2007 Physician United States
Primary
Concomitant
Rash Pustular Other Serious 7/20/2007 Male 215 lb 12/7/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 3/1/2007 75 Female 12/17/2007 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 12/17/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 199 lb 1/21/2008 Consumer United States
Primary
Concomitant
Scleritis Other Serious 11/15/2006 Female 2/4/2008 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 12/1/2006 Female 1/29/2008 Consumer United States
Primary
Concomitant
Scleritis Other Serious 11/15/2006 Female 2/29/2008 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 3/3/2008 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 6/29/2007 Male 3/13/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/16/2008 Female 132 lb 3/31/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 185 lb 5/13/2008 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 1/13/2008 55 Male 174 lb 5/21/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 185 lb 6/2/2008 Physician United States
Primary
Concomitant
Drug Ineffective 5/17/2007 75 Male 6/11/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 75 Male 205 lb 6/12/2008 United States
Primary
Concomitant
Myocardial Infarction Other Serious 65 Male 185 lb 7/18/2008 Consumer United States
Primary
Concomitant
Skin Tightness Male 162 lb 7/25/2008 Consumer United States
Primary
Concomitant
Gait Disturbance Disability 74 Female 8/18/2008 Consumer Canada
Primary
Concomitant
Ulcerative Keratitis Hospitalization 10/3/2008 75 Male 10/28/2008 Japan
Primary
Concomitant
Weight Decreased Other Serious 7/17/2008 58 Male 210 lb 11/7/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 10/3/2008 75 Male 11/12/2008 Japan
Primary
Concomitant
Visual Acuity Reduced Hospitalization 10/3/2008 75 Male 11/18/2008 Japan
Primary
Concomitant
Rash 11/7/2007 74 Male 11/28/2008 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/3/2008 Male 12/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 11/1/2007 68 Male 178 lb 12/10/2008 Consumer United States
Primary
Concomitant
Helicobacter Gastritis 63 Female 135 lb 12/17/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization Male 12/24/2008 Physician Bulgaria
Primary
Concomitant
Lung Disorder Death 9/29/2008 50 Male 1/6/2009 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 1/1/1997 Female 200 lb 1/15/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 9/16/2008 63 Female 185 lb 1/26/2009 Other Health Professional United States
Primary
Concomitant
Heart Rate Irregular 75 Male 180 lb 4/21/2009 Consumer United States
Primary
Concomitant
Interacting
Blood Lactic Acid Increased Death 3/2/2009 55 Male 5/11/2009 Physician Switzerland
Primary
Secondary
Concomitant
Oedema Hospitalization 63 Female 7/21/2009 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Urticaria 5/27/2009 Male 180 lb 8/22/2009 United States
Primary
Concomitant
Pruritus 6/2/2009 240 lb 8/22/2009 United States
Primary
Concomitant
Flushing 10/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2009 65 Male 8/26/2009 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/7/2009 49 Female 9/18/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/7/2009 49 Female 10/6/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Nausea Death 3/2/2009 55 Male 11/6/2009 Physician Switzerland
Primary
Secondary
Concomitant
Depression 1/1/2009 Female 3/16/2010 Pharmacist United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 1/1/2010 Female 172 lb 3/31/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 64 Female 4/15/2010 Consumer United States
Primary
Concomitant
Death Death Female 4/16/2010 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 2/26/2010 58 Male 207 lb 5/21/2010 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/1/2010 70 Male 7/2/2010 Pharmacist Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/1/2010 69 Male 8/13/2010 Pharmacist Japan
Primary
Concomitant
Pneumonia Hospitalization 7/21/2005 84 Male 9/24/2010 Physician Korea, Republic Of
Primary
Concomitant
Oedema Peripheral Hospitalization 7/30/2005 79 Male 9/24/2010 Physician Korea, Republic Of
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/5/2009 68 Male 9/24/2010 Pharmacist Japan
Primary
Concomitant
Gastritis Haemorrhagic Hospitalization 7/23/2005 70 Female 10/20/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 6/28/2010 72 Male 200 lb 10/15/2010 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/5/2009 68 Male 10/27/2010 Pharmacist Japan
Primary
Concomitant
Oedema Peripheral Other Serious Male 10/29/2010 Consumer United States
Primary
Concomitant
Hypoaesthesia Oral Hospitalization Female 11/3/2010 Physician Korea, Republic Of
Primary
Concomitant
Chest Pain Hospitalization 8/22/2005 67 Female 11/3/2010 Physician Korea, Republic Of
Primary
Concomitant
Chest Pain Hospitalization 5/26/2005 77 Male 11/3/2010 Physician Korea, Republic Of
Primary
Concomitant
Myalgia 10/1/2009 79 Male 172 lb 12/14/2010 Consumer United States
Primary
Concomitant
Anxiety 78 Male 190 lb 12/14/2010 Consumer United States
Primary
Concomitant
Increased Tendency To Bruise 77 Female 169 lb 12/14/2010 United States
Primary
Concomitant
Pain In Extremity 65 Female 195 lb 12/14/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 68 Female 180 lb 12/14/2010 Consumer United States
Primary
Concomitant
Myalgia 82 Male 12/14/2010 Consumer United States
Primary
Concomitant
Septic Arthritis Staphylococcal Hospitalization 9/2/2010 63 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Fall 10/12/2010 86 Female 12/22/2010 Consumer United States
Primary
Concomitant
Lip Swelling 12/1/2010 81 Male 1/10/2011 Consumer
Primary
Concomitant
Pneumonia Hospitalization 10/12/2010 60 Female 212 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/14/2011 77 Male 1/21/2011 Consumer United States
Primary
Concomitant
Crohn's Disease Hospitalization 7/1/2009 51 Male 140 lb 1/28/2011 Consumer United States
Primary
Concomitant
Rash Papular 6/1/2010 64 Female 1/29/2011 Consumer United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 9/1/2010 65 Male 2/25/2011 Pharmacist United States
Primary
Concomitant
Haemorrhage Hospitalization 1/19/2011 58 Female 235 lb 1/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease 1/26/2011 64 Female 3/10/2011 Consumer United States
Primary
Concomitant
Gallbladder Disorder Other Serious 12/1/2010 58 Male 258 lb 3/11/2011 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 2/20/2011 75 Male 3/25/2011 Consumer United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/12/2011 86 Female 150 lb 3/2/2011 Pharmacist United States
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 1/1/2009 58 Male 218 lb 4/1/2011 Consumer United States
Primary
Concomitant
Dizziness 11/1/2010 87 Female 4/8/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 1/1/2009 59 Male 218 lb 4/8/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Tinnitus 4/1/2011 Male 4/22/2011 Consumer United States
Primary
Concomitant
Anxiety Hospitalization 7/20/2002 64 Male 172 lb 4/28/2011 Lawyer United States
Primary
Concomitant
Fall 3/1/2011 77 Female 5/9/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased Male 5/10/2011 Consumer United States
Primary
Concomitant
Acute Respiratory Failure Other Serious 3/17/2011 91 Male 5/18/2011 Physician United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 2/1/2006 59 Female 206 lb 5/26/2011 Pharmacist United States
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 12/5/2010 75 Male 6/8/2011 Physician Japan
Primary
Concomitant
Cataract Hospitalization 1/5/2009 68 Male 6/13/2011 Pharmacist Japan
Primary
Concomitant
Blood Creatinine Increased Disability 3/12/2011 68 Male 6/17/2011 Physician Japan
Primary
Concomitant
Dysphagia Other Serious 5/16/2011 78 Female 7/6/2011 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 60 Female 7/12/2011 Physician Mexico
Primary
Concomitant
Pain Other Serious 7/7/2006 73 Male 200 lb 7/13/2011 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious Female 201 lb 7/15/2011 Consumer United States
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 10/5/2010 32 Male 194 lb 7/18/2011 Physician Japan
Primary
Concomitant
Death Death 6/9/2007 61 Male 263 lb 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 6/17/2011 81 Female 7/27/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Throat Irritation Disability 5/16/2011 78 Female 7/28/2011 Physician Japan
Primary
Concomitant
Epistaxis Death 7/1/2011 78 Female 8/1/2011 Other Health Professional Ireland
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2007 69 Female 147 lb 8/2/2011 Lawyer United States
Primary
Concomitant
Rash Female 275 lb 8/5/2011 Consumer United States
Primary
Concomitant
Pruritus Male 250 lb 8/5/2011 Consumer United States
Primary
Concomitant
Feeling Jittery Female 8/5/2011 Consumer United States
Primary
Concomitant
Decreased Appetite 6/1/2010 55 Female 8/5/2011 Consumer United States
Primary
Concomitant
Cough Male 222 lb 8/5/2011 Consumer United States
Primary
Concomitant
Feeling Hot 11/1/2010 64 Female 138 lb 8/5/2011 Consumer United States
Primary
Concomitant
Insomnia 8/4/2010 63 Female 182 lb 8/5/2011 Consumer United States
Primary
Concomitant
Flushing 6/10/2010 Male 210 lb 8/5/2011 Consumer United States
Primary
Concomitant
Diarrhoea Male 106 lb 8/6/2011 Consumer United States
Primary
Concomitant
Flushing Female 205 lb 8/6/2011 Consumer United States
Primary
Concomitant
Pruritus 1/1/2009 66 Male 197 lb 8/6/2011 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness 6/1/2011 46 Male 195 lb 8/6/2011 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 7/6/2011 43 Female 8/9/2011 Physician France
Primary
Concomitant
Pyrexia Hospitalization 7/21/2011 51 Female 150 lb 8/9/2011 Pharmacist Japan
Primary
Secondary
Epistaxis 7/1/2011 78 Female 8/10/2011 Physician Ireland
Primary
Concomitant
Renal Failure Hospitalization 7/21/2011 51 Female 150 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Haemorrhagic Disorder Other Serious 6/6/2011 77 Female 125 lb 8/15/2011 Physician France
Primary
Secondary
Concomitant
Pain In Jaw 10/1/2010 79 Female 8/16/2011 Consumer United States
Primary
Concomitant
Prothrombin Level Decreased Other Serious 9/12/2009 48 Male 8/11/2011 France
Primary
Concomitant
Renal Impairment Other Serious 7/18/2011 51 Female 150 lb 8/19/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 7/18/2011 51 Female 150 lb 8/19/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 3/10/2007 65 Male 164 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Life Threatening 7/1/2011 76 Female 8/24/2011 Physician Japan
Primary
Concomitant
Oesophageal Discomfort Other Serious 5/16/2011 78 Female 117 lb 8/25/2011 Physician Japan
Primary
Concomitant
Drug Interaction Hospitalization 6/17/2011 81 Female 8/25/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Oedema Peripheral 8/15/2011 69 Male 147 lb 8/29/2011 Other Health Professional United States
Primary
Concomitant
Arthralgia Hospitalization 7/18/2011 51 Female 150 lb 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Headache Hospitalization 7/18/2011 51 Female 150 lb 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Other Serious 9/5/2010 77 Female 181 lb 9/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Headache Hospitalization 7/18/2011 51 Female 150 lb 9/9/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/18/2011 51 Female 150 lb 9/9/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 6/5/2011 76 Female 9/12/2011 Physician Japan
Primary
Concomitant
Cerebral Infarction Hospitalization 7/25/2011 76 Female 128 lb 9/9/2011 Physician Japan
Primary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 6/5/2011 76 Female 9/19/2011 Physician Japan
Primary
Concomitant

Drug Data