Coumadin combined with Vitamin B-12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Output Decreased Hospitalization 10/1/2005 Female 1/4/2006 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/12/2006 Female 195 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/1/2005 73 Male 1/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 8/24/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Drug Abuser Death 2/24/2006 53 Female 3/29/2006 Physician United States
Primary
Concomitant
Weight Decreased 9/1/2005 64 Male 217 lb 1/20/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 9/6/2005 86 Female 5/8/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/1/2005 Male 5/30/2006 Lawyer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 3/1/2006 Male 6/16/2006 Physician United States
Primary
Concomitant
Urticaria Generalised Other Serious 8/4/2005 58 Male 176 lb 4/17/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization Male 7/11/2006 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/7/2006 66 Female 161 lb 7/25/2006 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Rash Erythematous 1/1/2005 88 Female 110 lb 8/1/2006 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 1/1/2004 70 Female 115 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 8/2/2005 69 Male 240 lb 8/1/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/1/2002 75 Female 148 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 50 Male 190 lb 8/1/2006 Consumer United States
Primary
Concomitant
Oedema 80 Female 123 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Abnormal 82 Male 141 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Abnormal 1/10/2006 80 Male 8/1/2006 Consumer United States
Primary
Concomitant
Tachycardia 2/2/2006 Male 180 lb 8/4/2006 Physician United States
Primary
Concomitant
Psychomotor Hyperactivity 2/1/2005 Female 8/8/2006 Consumer United States
Primary
Concomitant
Self-medication Hospitalization 7/7/2006 66 Female 161 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Drug Abuser Death 2/24/2006 53 Female 9/6/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 7/3/2006 50 Female 150 lb 10/26/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 7/3/2006 50 Female 150 lb 10/26/2006 Physician United States
Primary
Concomitant
Self-medication Hospitalization 7/7/2006 66 Female 161 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Skin Discolouration 9/1/2005 80 Male 11/13/2006 Consumer United States
Primary
Concomitant
Dyspnoea 6/1/2006 90 Male 11/13/2006 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 84 Male 159 lb 12/8/2006 Physician Canada
Primary
Concomitant
International Normalised Ratio Increased 3/16/2006 Female 12/22/2006 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 9/1/2005 65 Female 206 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 9/6/2006 70 Male 1/24/2007 Other Health Professional France
Primary
Concomitant
Interacting
Therapeutic Response Decreased 2/27/2006 Male 127 lb 1/24/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 7/1/2005 Male 1/22/2007 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/1/2005 79 Male 2/7/2007 Consumer United States
Primary
Concomitant
Interacting
Transient Ischaemic Attack Other Serious 70 Female 145 lb 6/2/2006 United States
Primary
Concomitant
Weight Increased Other Serious 9/15/2006 56 Male 280 lb 2/8/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 9/15/2006 56 Male 280 lb 2/12/2007 Physician United States
Primary
Concomitant
Cardiomyopathy Other Serious 4/1/2006 50 Male 183 lb 2/21/2007 Other Health Professional United States
Primary
Concomitant
Gingival Pain Other Serious 10/19/2006 81 Female 146 lb 11/28/2006 United States
Primary
Concomitant
Fatigue Other Serious 1/1/2005 75 Female 4/21/2007 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 5/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2005 75 Female 5/8/2007 United States
Primary
Concomitant
Vomiting Hospitalization 5/2/2007 Female 114 lb 5/3/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/2/2007 68 Female 5/8/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 5/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphoma Other Serious 3/1/2007 Female 185 lb 5/18/2007 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 8/1/2002 57 Female 149 lb 6/11/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 4/5/2007 61 Female 97 lb 6/14/2007 Other Health Professional United States
Primary
Concomitant
Death Death Female 216 lb 6/19/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased 10/12/2006 Male 6/26/2007 Consumer United States
Primary
Concomitant
Breast Mass Other Serious 3/1/2007 Female 185 lb 7/10/2007 Physician United States
Primary
Concomitant
Salmonellosis Other Serious 7/1/2007 Male 155 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Other Serious 4/1/2006 Female 7/24/2007 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 1/1/2006 80 Female 7/25/2007 Physician United States
Primary
Secondary
Concomitant
Tongue Haematoma Hospitalization 6/7/2006 68 Female 8/1/2007 Pharmacist United States
Primary
Secondary
Concomitant
Angioedema Hospitalization 6/7/2006 68 Female 8/1/2007 Pharmacist United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 8/1/2002 57 Female 149 lb 8/16/2007 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 8/31/2004 71 Male 209 lb 2/28/2005 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 70 Female 130 lb 9/12/2007 Consumer United States
Primary
Concomitant
Gastric Haemorrhage Other Serious Female 9/25/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 8/1/2002 57 Female 149 lb 10/8/2007 Physician United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 9/7/2006 90 Male 11/12/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 4/5/2007 61 Female 97 lb 11/15/2007 Other Health Professional United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 11/8/2007 Male 273 lb 2/22/2008 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 9/8/2006 Male 3/18/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/30/2007 47 Female 3/17/2008 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 9/8/2006 Male 3/27/2008 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/7/2007 82 Female 173 lb 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 4/22/2008 Physician Canada
Primary
Concomitant
Hypoxia Hospitalization 4/9/2008 Male 239 lb 4/21/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 9/30/2007 47 Female 4/18/2008 Physician United States
Primary
Concomitant
Vision Blurred 75 Female 135 lb 4/29/2008 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 3/27/2008 76 Female 5/13/2008 Physician Canada
Primary
Concomitant
Death Death Male 5/20/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 84 Female 5/30/2008 Pharmacist Canada
Primary
Concomitant
Renal Failure Death 3/1/2008 Male 6/2/2008 Physician United States
Primary
Concomitant
Hypersomnia Death 12/1/2007 Male 146 lb 6/17/2008 Consumer United States
Primary
Concomitant
Vasculitis 4/3/2008 Male 6/25/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 10/16/2007 Female 120 lb 4/14/2008 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/9/2008 Male 239 lb 6/26/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/1/2008 71 Male 172 lb 7/1/2008 United States
Primary
Concomitant
Generalised Oedema Other Serious 10/29/2007 68 Male 163 lb 7/7/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vasculitis 4/3/2008 Male 7/8/2008 Consumer United States
Primary
Concomitant
Pyrexia 5/2/2008 Female 7/3/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/29/2008 75 Female 7/16/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 1/1/2008 Male 7/17/2008 Other Health Professional United States
Primary
Concomitant
Hypersomnia Death 12/1/2007 Male 146 lb 7/18/2008 Physician United States
Primary
Concomitant
Respiratory Rate Increased 9/16/2007 Female 7/25/2008 Consumer
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/1/2007 84 Female 170 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation Other Serious 9/27/2007 78 Male 150 lb 7/29/2008 Consumer Germany
Primary
Concomitant
International Normalised Ratio Increased 72 Male 181 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Oesophageal Pain 75 Female 229 lb 7/29/2008 Consumer United States
Primary
Concomitant
Contusion 84 Male 132 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 81 Female 172 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 11/8/2007 76 Female 170 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Fluctuation Other Serious Female 150 lb 7/29/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 6/29/2008 75 Female 227 lb 8/4/2008 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 8/1/2002 57 Female 150 lb 8/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 5/20/2008 Male 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/4/2008 Female 178 lb 8/22/2008 Physician United States
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 7/17/2008 Female 121 lb 9/3/2008 Physician United States
Primary
Concomitant
Treatment Failure Other Serious 5/20/2008 Male 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 10/28/2007 69 Male 9/23/2008 Consumer United States
Primary
Concomitant
Lethargy 9/14/2008 95 Male 121 lb 9/25/2008 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 9/6/2008 Male 10/10/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 10/11/2003 72 Female 180 lb 10/24/2008 United States
Primary
Concomitant
Skin Tightness Other Serious 11/1/2006 51 Female 141 lb 10/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 Male 237 lb 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 11/1/2006 51 Female 141 lb 10/30/2008 Lawyer United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Other Serious 1/1/2008 54 Male 221 lb 11/5/2008 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected 71 Female 11/13/2008 Consumer United States
Primary
Concomitant
Anaemia Other Serious 2/1/2008 Female 11/11/2008 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 11/1/2006 51 Female 141 lb 11/20/2008 Lawyer United States
Primary
Secondary
Concomitant
Pancreatic Neuroendocrine Tumour Other Serious 1/1/2008 54 Male 220 lb 11/21/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/4/2007 Female 11/24/2008 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2001 Male 150 lb 11/24/2008 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 9/6/2008 Male 11/25/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 5/4/2007 Female 12/1/2008 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 9/1/2008 Female 12/1/2008 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 9/6/2008 Male 12/10/2008 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 11/1/2007 Female 12/11/2008 Consumer United States
Primary
Concomitant
Staphylococcal Abscess Other Serious 10/8/2008 66 Female 151 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/1/2008 Male 130 lb 12/23/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 12/26/2008 Consumer United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 1/5/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2008 Female 105 lb 1/12/2009 Physician United States
Primary
Concomitant
Interacting
Vena Cava Thrombosis Other Serious 1/1/2006 31 Female 231 lb 1/15/2009 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 12/16/2008 Female 1/21/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 10/11/2008 Male 130 lb 1/20/2009 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 12/16/2008 Female 1/28/2009 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 12/12/2008 74 Female 2/4/2009 Consumer United States
Primary
Concomitant
Malaise Hospitalization 73 Male 280 lb 1/29/2009 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Death 1/1/2009 Female 2/9/2009 Consumer United States
Primary
Secondary
Concomitant
Night Sweats Other Serious 3/1/2008 Female 132 lb 2/13/2009 Canada
Primary
Concomitant
Pruritus 12/15/2008 Male 2/24/2009 United States
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 1/1/2007 Female 2/13/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral Death Female 220 lb 2/26/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 87 Female 105 lb 3/2/2009 Pharmacist United States
Primary
Concomitant
Death Death Female 3/10/2009 Consumer United States
Primary
Concomitant
Death Death 1/9/2009 Male 3/6/2009 Consumer United States
Primary
Concomitant
Thinking Abnormal Other Serious 1/1/2007 Female 3/24/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death Female 213 lb 3/27/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/28/2002 71 Female 167 lb 4/3/2009 United States
Primary
Concomitant
Weight Increased 5/1/2008 70 Female 3/23/2009 United States
Primary
Concomitant
Product Quality Issue 9/1/2008 55 Female 3/31/2009 Consumer United States
Primary
Concomitant
Renal Failure Death Female 4/7/2009 Physician United States
Primary
Concomitant

Drug Data