Coumadin combined with Tykerb

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Swelling Face Hospitalization 5/12/2007 78 Male 5/17/2007 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious Female 5/21/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 5/1/2007 46 Female 5/23/2007 Consumer United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 4/21/2007 59 Female 5/24/2007 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 4/1/2007 54 Female 5/25/2007 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 5/12/2007 78 Male 6/5/2007 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 4/1/2007 52 Female 6/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 4/21/2007 59 Female 6/20/2007 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 6/1/2007 78 Female 7/2/2007 Consumer United States
Primary
Concomitant
Fatigue 4/1/2007 58 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 4/1/2007 52 Female 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 4/15/2007 64 Female 7/6/2007 Consumer United States
Primary
Concomitant
Paraesthesia 4/1/2007 59 Female 7/6/2007 Consumer United States
Primary
Concomitant
Oral Pain 5/4/2007 46 Female 7/6/2007 Consumer United States
Primary
Concomitant
Rash 4/1/2007 43 Female 150 lb 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 5/16/2007 89 Female 134 lb 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 63 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 5/16/2007 47 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 5/16/2007 53 Female 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 5/11/2007 50 Female 203 lb 7/6/2007 Consumer United States
Primary
Concomitant
Vomiting 5/1/2007 81 Female 7/6/2007 Consumer United States
Primary
Concomitant
Stomach Discomfort 5/24/2007 60 Female 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Fatigue 5/1/2007 53 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 49 Female 138 lb 7/6/2007 Other Health Professional United States
Primary
Concomitant
Diarrhoea 5/1/2007 59 Female 7/6/2007 Consumer United States
Primary
Concomitant
Skin Chapped 5/1/2007 49 Female 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Dry Skin 5/1/2007 42 Female 7/6/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 7/1/2007 64 Female 7/10/2007 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 5/12/2007 78 Male 7/27/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2007 78 Female 7/27/2007 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 5/12/2007 78 Male 7/30/2007 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 4/1/2007 54 Female 7/30/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2007 78 Female 7/30/2007 Consumer United States
Primary
Concomitant
Blister Other Serious 7/28/2007 45 Female 8/7/2007 Consumer United States
Primary
Concomitant
Dementia Other Serious 5/1/2007 83 Female 8/8/2007 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/16/2007 53 Female 8/21/2007 Consumer United States
Primary
Secondary
Concomitant
Skin Chapped Other Serious 8/1/2007 54 Female 8/22/2007 Consumer United States
Primary
Concomitant
Gastroenteritis Viral Other Serious 9/9/2007 52 Female 10/9/2007 Consumer United States
Primary
Concomitant
Gastroenteritis Viral Other Serious 9/9/2007 52 Female 10/9/2007 Consumer United States
Primary
Concomitant
Skin Chapped 5/1/2007 49 Female 297 lb 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 5/1/2007 60 Female 10/11/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Female 10/11/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia 6/24/2007 56 Female 10/11/2007 Consumer United States
Primary
Concomitant
Weight Decreased 6/22/2007 39 Female 10/11/2007 Consumer United States
Primary
Concomitant
Nausea 7/1/2007 55 Female 10/11/2007 Consumer United States
Primary
Concomitant
Skin Ulcer 6/1/2007 52 Female 120 lb 10/11/2007 Consumer United States
Primary
Concomitant
Rash 6/1/2007 60 Female 10/11/2007 Consumer United States
Primary
Concomitant
Nausea 69 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 6/7/2007 52 Female 145 lb 12/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Chapped Other Serious 8/1/2007 54 Female 213 lb 12/19/2007 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 32 Female 2/12/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/9/2008 32 Female 2/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 155 lb 3/28/2008 Consumer United States
Primary
Concomitant
Nausea 1/20/2008 82 Female 4/10/2008 Consumer United States
Primary
Concomitant
Nausea Other Serious 6/6/2007 52 Female 145 lb 6/29/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia 5/2/2008 Female 7/3/2008 Consumer United States
Primary
Concomitant
Swelling Face Hospitalization 5/12/2007 78 Male 7/15/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 5/12/2007 78 Female 7/15/2008 Consumer United States
Primary
Concomitant
Pain In Extremity 1/14/2008 57 Female 227 lb 10/10/2008 Consumer United States
Primary
Concomitant
Diarrhoea 9/9/2008 76 Female 10/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2007 52 Female 120 lb 11/12/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2007 52 Female 120 lb 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity 2/14/2009 60 Female 4/2/2009 Consumer United States
Primary
Concomitant
Pruritus 2/24/2009 60 Female 4/2/2009 Consumer United States
Primary
Concomitant
Pain In Extremity 2/26/2009 59 Female 4/2/2009 Consumer United States
Primary
Concomitant
Vomiting 63 Female 4/2/2009 Consumer United States
Primary
Secondary
Concomitant
Somnolence 2/27/2009 56 Female 4/2/2009 Consumer United States
Primary
Concomitant
Pruritus 2/24/2009 60 Female 7/10/2009 Consumer United States
Primary
Concomitant
Rash 4/9/2009 66 Male 7/10/2009 Consumer United States
Primary
Concomitant
Onychomycosis 3/1/2009 54 Female 7/10/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/3/2009 47 Female 9/10/2009 Consumer United States
Primary
Concomitant
Rash 46 Female 9/24/2009 Consumer United States
Primary
Concomitant
Vomiting 5/25/2009 69 Female 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Nausea 8/4/2009 83 Female 9/24/2009 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 8/10/2009 47 Female 314 lb 9/24/2009 Consumer United States
Primary
Concomitant
Death Death 10/4/2009 52 Female 10/15/2009 Consumer United States
Primary
Concomitant
Wound Hospitalization 9/1/2009 55 Male 10/30/2009 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 11/9/2009 51 Female 12/3/2009 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 12/1/2009 Female 1/4/2010 Consumer United States
Primary
Concomitant
Nausea 8/4/2009 83 Female 150 lb 1/8/2010 Consumer United States
Primary
Concomitant
Weight Decreased 9/21/2009 63 Female 1/8/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting 11/5/2009 56 Female 1/8/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 3/1/2009 Female 2/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/1/2002 Female 146 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/29/2007 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Skin Laceration 52 Female 4/9/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 11/29/2007 55 Female 4/11/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 4/14/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 4/22/2010 United States
Primary
Concomitant
Tumour Marker Increased Other Serious Female 5/14/2010 Consumer Canada
Primary
Concomitant
Ventricular Fibrillation Hospitalization Female 5/19/2010 Consumer Canada
Primary
Concomitant
Vomiting Other Serious 66 Female 6/4/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 6/7/2010 United States
Primary
Concomitant
Fatigue Other Serious 87 Female 7/14/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 7/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 145 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 56 Female 8/25/2010 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 87 Female 8/26/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 8/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 145 lb 9/1/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 9/8/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 145 lb 9/16/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 145 lb 9/28/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1995 47 Male 10/5/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 10/15/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 10/29/2010 United States
Primary
Concomitant
Disease Progression Death 52 Female 11/2/2010 Consumer United States
Primary
Concomitant
Death Life Threatening 54 Female 11/8/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 11/11/2010 United States
Primary
Concomitant
Weight Decreased Death 39 Female 12/20/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 2/18/2009 52 Female 145 lb 12/22/2010 United States
Primary
Secondary
Concomitant
Abdominal Discomfort Death 39 Female 1/13/2011 Consumer United States
Primary
Concomitant
Adverse Event Life Threatening 54 Female 1/28/2011 Consumer United States
Primary
Concomitant
Nausea Death 39 Female 2/2/2011 Consumer United States
Primary
Concomitant
Drug Ineffective Death 39 Female 2/18/2011 Other Health Professional United States
Primary
Concomitant
Head Injury Death 11/29/2004 53 Female 3/18/2011 Physician United States
Primary
Concomitant
Blood Pressure Increased Other Serious 11/16/2007 55 Female 276 lb 3/29/2011 United States
Primary
Concomitant
Hypotension Other Serious 11/16/2007 55 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Aspiration Hospitalization 11/29/2004 53 Female 4/27/2011 Physician United States
Primary
Concomitant
Breast Cancer Metastatic Death 57 Female 4/27/2011 Consumer United States
Primary
Secondary
Concomitant
Asthenia 1/20/2008 82 Female 5/2/2011 Consumer United States
Primary
Concomitant
Glossodynia 3/9/2010 49 Female 5/2/2011 Consumer United States
Primary
Concomitant
Aspiration Death 11/29/2004 53 Female 5/19/2011 Physician United States
Primary
Concomitant
Abdominal Distension Hospitalization 2/18/2009 52 Female 145 lb 5/23/2011 Physician United States
Primary
Secondary
Concomitant
Fatigue Other Serious 11/16/2007 55 Female 276 lb 6/13/2011 Lawyer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 11/16/2007 55 Female 276 lb 7/4/2011 Physician United States
Primary
Concomitant
Breast Cancer Metastatic Death 57 Female 7/22/2011 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 11/16/2007 55 Female 101 lb 8/2/2011 Physician United States
Primary
Concomitant
Electrolyte Imbalance Hospitalization 1/1/2009 68 Female 8/25/2011 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2007 59 Male 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Electrolyte Imbalance Hospitalization 1/1/2009 68 Female 10/4/2011 Consumer United States
Primary
Secondary
Concomitant
Depression Other Serious 10/27/2010 59 Female 230 lb 10/4/2011 Consumer United States
Primary
Concomitant
Overdose Other Serious Male 11/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hot Flush Other Serious 5/31/2006 54 Female 148 lb 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Hypertension Other Serious 5/31/2006 54 Female 148 lb 11/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/4/2011 53 Male 12/5/2011 Consumer United States
Primary
Concomitant
Confusional State Other Serious 5/31/2006 54 Female 148 lb 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Hypoxia Hospitalization 2/1/2012 81 Female 3/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Deformity Other Serious Male 3/30/2012 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 5/31/2006 54 Female 148 lb 4/6/2012 Lawyer United States
Primary
Secondary
Concomitant
Coagulopathy Other Serious 2/1/2012 81 Female 144 lb 4/11/2012 Consumer United States
Primary
Secondary
Concomitant
Constipation 1/1/2000 48 Female 4/23/2012 Consumer United States
Primary
Secondary
Concomitant
Oral Herpes 4/1/2007 43 Female 150 lb 5/11/2012 Consumer United States
Primary
Concomitant
Dyspepsia 2/27/2009 56 Female 5/11/2012 Consumer United States
Primary
Concomitant
Lip Discolouration 2/1/2010 52 Female 5/11/2012 Consumer United States
Primary
Concomitant
Diarrhoea 5/1/2011 53 Female 211 lb 5/11/2012 Consumer United States
Primary
Concomitant
Hypoaesthesia Oral 6/6/2011 44 Female 5/11/2012 Consumer United States
Primary
Concomitant
Condition Aggravated 8/2/2011 64 Female 5/11/2012 Consumer United States
Primary
Concomitant
Death Death 3/12/2012 51 Female 6/19/2012 Other Health Professional United States
Primary
Concomitant
Death Death 45 Female 7/11/2012 Consumer United States
Primary
Concomitant

Drug Data