Coumadin combined with Toprol-XL

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebral Haemorrhage Hospitalization 5/16/2004 85 Male 176 lb 1/6/2006 Physician United States
Primary
Concomitant
Splenorenal Shunt Other Serious 1/1/2005 58 Male 230 lb 1/3/2006 Physician United States
Primary
Concomitant
Prostatic Disorder Hospitalization 2/1/2001 55 Male 251 lb 1/13/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 87 Female 150 lb 1/18/2006 Physician United States
Primary
Concomitant
Vertigo Other Serious 1/1/1999 59 Female 161 lb 1/19/2006 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/3/2006 78 Female 247 lb 1/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/12/2002 55 Male 251 lb 1/23/2006 Physician United States
Primary
Concomitant
Embolism Hospitalization 1/1/2001 81 Female 1/23/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 1/12/2006 Female 195 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/1/2001 78 Male 150 lb 1/24/2006 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 11/22/2005 65 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Hypoglycaemic Coma Hospitalization 5/1/1995 82 Male 176 lb 2/1/2006 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 3/16/2004 74 Unknown 165 lb 1/24/2006 Lawyer United States
Primary
Concomitant
Spinal Cord Compression Hospitalization 8/1/2003 76 Male 1/18/2006 Physician United States
Primary
Concomitant
Impaired Healing 5/25/2005 77 Male 12/7/2005 Other Health Professional United States
Primary
Concomitant
Rash 88 Male 138 lb 12/7/2005 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 2/1/2005 Female 1/31/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/23/2005 57 Female 286 lb 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2003 70 Male 2/8/2006 United States
Primary
Concomitant
Pain In Extremity Other Serious 1/3/2006 78 Female 247 lb 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Face Hospitalization 2/1/2006 67 Female 174 lb 2/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Red Cell Distribution Width Increased Other Serious 12/22/2005 47 Male 198 lb 2/7/2006 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/17/2005 Female 160 lb 10/14/2005 Pharmacist United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 4/30/2005 Male 350 lb 12/8/2005 Pharmacist United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 5/16/2004 85 Male 176 lb 2/17/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 2/21/2006 Physician United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 6/1/1999 75 Male 2/21/2006 Physician United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 1/1/2001 88 Female 154 lb 2/21/2006 Physician United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 7/1/2002 65 Male 220 lb 2/23/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/25/2001 65 Female 161 lb 2/24/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 11/14/2005 97 Female 1/12/2006 Other Health Professional United States
Primary
Concomitant
Vestibular Disorder Other Serious 1/1/2004 85 Male 1/17/2006 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2002 78 Male 225 lb 2/27/2006 Lawyer United States
Primary
Concomitant
Spinal Compression Fracture Hospitalization 8/1/2003 76 Male 2/14/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 12/27/2003 67 Male 196 lb 3/3/2006 Physician United States
Primary
Concomitant
Ureteral Disorder Other Serious 7/1/2000 63 Male 187 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 8/1/2001 70 Male 159 lb 3/8/2006 Lawyer United States
Primary
Concomitant
Chest Pain Hospitalization 2/26/2006 64 Female 195 lb 3/8/2006 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 2/1/2001 63 Male 209 lb 3/15/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 3/16/2006 Physician United States
Primary
Concomitant
Renal Cyst Other Serious 11/1/2005 80 Female 176 lb 3/16/2006 Consumer United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 6/1/1999 75 Male 3/17/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 3/6/2003 80 Male 147 lb 3/13/2006 United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 6/1/1999 76 Male 220 lb 3/20/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 10/31/2002 63 Male 161 lb 3/20/2006 Lawyer United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/4/2006 82 Female 178 lb 3/18/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/11/2005 85 Female 100 lb 3/1/2006 United States
Primary
Concomitant
Urinary Retention Hospitalization 8/29/2005 59 Male 3/9/2006 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2002 72 Female 251 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Urinary Retention Hospitalization 8/29/2005 59 Male 3/16/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/22/2004 Male 180 lb 3/2/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 3/24/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/1/2005 80 Female 135 lb 3/24/2006 United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2005 75 Male 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Regimen Changed Hospitalization 11/21/2003 88 Male 150 lb 3/27/2006 Lawyer United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 1/1/2001 74 Male 185 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 3/27/2006 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2005 75 Male 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 5/1/2005 88 Male 3/14/2006 Physician United States
Primary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 Consumer United States
Primary
Concomitant
Malignant Melanoma Other Serious Female 138 lb 3/31/2006 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2005 53 Female 3/23/2006 Physician United States
Primary
Concomitant
Throat Irritation Death 2/20/2006 72 Male 228 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/12/2002 55 Male 251 lb 4/3/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 4/4/2006 Physician United States
Primary
Concomitant
Venous Insufficiency Hospitalization 1/1/2004 43 Female 115 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 50 Female 196 lb 4/4/2006 Physician United States
Primary
Concomitant
Fatigue Other Serious 3/1/2006 64 Female 161 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Hypotension 5/3/2005 60 Male 164 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased 10/10/2005 63 Male 302 lb 1/20/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 75 Male 3/30/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 2/4/2006 82 Female 178 lb 4/7/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 4/10/2006 Physician United States
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 3/22/2006 50 Male 143 lb 3/30/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 7/27/2005 65 Female 2/8/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 4/11/2006 88 Female 77 lb 4/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 5/16/2004 85 Male 176 lb 4/14/2006 Physician United States
Primary
Concomitant
Renal Papillary Necrosis Other Serious 3/1/2006 Female 4/14/2006 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2005 51 Male 248 lb 4/14/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Death 11/15/2005 73 Male 230 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 12/1/1999 Male 280 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 12/1/2005 80 Male 162 lb 4/7/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/4/2006 46 Male 232 lb 4/7/2006 Other Health Professional United States
Primary
Concomitant
Libido Decreased 8/1/2005 Male 1/27/2006 Consumer United States
Primary
Concomitant
Swollen Tongue Hospitalization 2/23/2006 72 Female 4/13/2006 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 3/1/2006 64 Female 161 lb 4/11/2006 United States
Primary
Secondary
Concomitant
Heart Rate Decreased Required Intervention 1/1/2000 83 Male 4/11/2006 United States
Primary
Secondary
Concomitant
Incision Site Complication Other Serious 1/1/2006 Female 135 lb 4/19/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/26/2006 64 Female 195 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/12/2006 77 Male 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 5/3/2002 75 Female 106 lb 4/25/2006 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2006 77 Male 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Polytraumatism Other Serious 8/21/2003 83 Male 236 lb 4/26/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Hospitalization 5/16/2004 85 Male 176 lb 4/28/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 11/25/2003 43 Female 115 lb 5/1/2006 Physician United States
Primary
Concomitant
Rash Other Serious 1/1/2002 75 Female 106 lb 5/1/2006 Physician United States
Primary
Concomitant
White Blood Cell Morphology Abnormal Other Serious 12/5/2005 Female 190 lb 5/2/2006 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 12/1/2005 80 Male 162 lb 4/24/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3/1/2004 77 Male 4/26/2006 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 8/1/2005 77 Male 145 lb 5/4/2006 Consumer United States
Primary
Concomitant
Petechiae Required Intervention 4/18/2006 80 Female 176 lb 5/1/2006 Physician United States
Primary
Concomitant
Dyspnoea 9/1/2005 81 Female 2/21/2006 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 2/1/2001 63 Male 209 lb 5/8/2006 Physician United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 1/1/2003 58 Male 198 lb 5/8/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 3/1/2006 64 Female 161 lb 5/2/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/26/2001 Female 125 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 5/8/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 4/14/2001 64 Male 240 lb 5/9/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 12/27/2003 67 Male 196 lb 5/11/2006 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 5/7/2006 58 Male 134 lb 5/9/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/23/2006 70 Female 150 lb 5/5/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 47 Female 241 lb 5/11/2006 Consumer United States
Primary
Secondary
Concomitant
Ureteral Disorder Other Serious 7/1/2000 63 Male 187 lb 5/11/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 9/1/2005 Female 112 lb 5/15/2006 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged 4/23/2006 88 Male 166 lb 4/27/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Death 2/20/2006 72 Male 228 lb 5/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious Female 132 lb 5/17/2006 Other Health Professional United States
Primary
Concomitant
Heart Rate Decreased Hospitalization 5/8/2006 65 Female 232 lb 5/12/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 3/28/2001 59 Male 170 lb 5/17/2006 Physician United States
Primary
Concomitant
Retinopathy Other Serious 3/1/2005 75 Male 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence 11/1/2005 75 Male 3/12/2006 United States
Primary
Concomitant
Rash Other Serious 8/1/2004 73 Female 143 lb 5/12/2006 United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 9/1/2005 Male 132 lb Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 3/31/2006 Female 5/4/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 3/6/2003 75 Male 147 lb 5/17/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 3/28/2006 70 Male 5/5/2006 Physician United States
Primary
Concomitant
Pain In Extremity 11/16/2005 70 Male 3/23/2006 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious 2/1/2005 Female 134 lb 5/23/2006 United States
Primary
Secondary
Concomitant
Rhinorrhoea Life Threatening 3/29/2006 Female 5/31/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 75 Male 5/24/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 6/26/2001 73 Female 126 lb 6/2/2006 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious 9/21/2005 61 Female 148 lb 6/2/2006 Consumer United States
Primary
Concomitant
Dizziness Other Serious 1/17/2006 76 Female 166 lb 4/20/2006 United States
Primary
Concomitant
Lethargy Required Intervention 1/24/2006 80 Female 157 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Hypercholesterolaemia Death 68 Female 6/13/2006 Physician United States
Primary
Concomitant
Neuropathy Other Serious 1/1/2006 70 Male 197 lb 4/20/2006 United States
Primary
Secondary
Concomitant
Pain Of Skin 2/8/2006 62 Male 4/24/2006 United States
Primary
Concomitant
Tachycardia Required Intervention 4/21/2006 59 Male 159 lb 6/1/2006 Pharmacist United States
Primary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2006 75 Male 6/9/2006 Physician United States
Primary
Concomitant
Weight Increased Life Threatening Female 331 lb 6/23/2006 Physician United States
Primary
Concomitant
Somnolence Other Serious 3/1/2006 88 Female 136 lb 6/30/2006 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 6/1/2005 69 Male 6/28/2006 Consumer United States
Primary
Concomitant
Meningitis Death 8/1/2005 Male 250 lb 7/10/2006 Physician United States
Primary
Concomitant
Vein Disorder Other Serious 5/1/2006 58 Female 178 lb 6/27/2006 United States
Primary
Secondary
Concomitant
Insomnia 3/20/2006 70 Male 197 lb 5/24/2006 Consumer United States
Primary
Concomitant
Pruritus Disability 6/24/2006 90 Female 125 lb 7/13/2006 Pharmacist United States
Primary
Concomitant
Heart Rate Abnormal Disability 11/3/2003 65 Male 10/4/2005 Consumer United States
Primary
Concomitant

Drug Data