Coumadin combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Hospitalization 3/1/2004 63 Female 4/5/2005 Pharmacist United States
Primary
Concomitant
Hallucination, Visual Hospitalization 11/14/2005 40 Female 3/7/2006 Consumer United States
Primary
Concomitant
Hallucination, Visual Hospitalization 11/14/2005 40 Female 3/7/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 70 Female 2/13/2006 Physician United States
Primary
Concomitant
Spinal Disorder Other Serious 1/1/2001 62 Female 170 lb 3/30/2006 Lawyer United States
Primary
Concomitant
Spinal Disorder Other Serious 1/1/2001 62 Female 170 lb 4/18/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 4/1/2006 68 Female 4/24/2006 Consumer United States
Primary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
Purpura Other Serious 46 Female 211 lb 4/14/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/13/2006 67 Female 162 lb 5/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/13/2006 67 Female 162 lb 5/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity 11/16/2005 70 Male 3/23/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/13/2006 67 Female 162 lb 6/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/17/2006 69 Female 247 lb 5/31/2006 Physician United States
Primary
Concomitant
Somnolence 1/1/2005 42 Female 257 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 4/1/2006 68 Female 7/12/2006 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 6/1/2006 20 Female 176 lb 7/10/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 4/1/2006 68 Female 7/17/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 7/1/2005 84 Female 183 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 69 Male 146 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 7/1/2006 Male 295 lb 9/27/2006 Consumer United States
Primary
Concomitant
Tremor 9/14/2006 48 Male 293 lb 10/3/2006 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/6/2006 59 Female 140 lb 11/2/2006 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/6/2006 59 Female 140 lb 11/2/2006 Consumer United States
Primary
Concomitant
Iridocyclitis Other Serious 5/2/2005 43 Female 8/18/2006 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/6/2006 59 Female 140 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 10/6/2006 59 Female 141 lb 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 2/18/2007 48 Female 321 lb 4/2/2007 Physician United States
Primary
Concomitant
Ecchymosis Other Serious 42 Female 11/28/2006 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Female 5/17/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1999 Female 5/25/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 2/18/2007 48 Female 321 lb 6/22/2007 Physician United States
Primary
Concomitant
Convulsive Threshold Lowered Hospitalization 1/1/2007 Female 6/28/2007 Consumer Australia
Primary
Concomitant
Swelling Face Other Serious 6/1/2007 78 Female 7/2/2007 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage Other Serious 1/1/2007 Male 7/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2007 78 Female 7/27/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2007 78 Female 7/30/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/1/2007 Female 180 lb 8/13/2007 Consumer United States
Primary
Concomitant
Weight Decreased 3/1/2007 42 Male 267 lb 7/11/2007 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage Hospitalization 2/1/2007 Male 195 lb 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/18/2007 57 Female 119 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Vomiting 65 Male 10/8/2007 Other Health Professional United States
Primary
Concomitant
Insomnia Death 54 Female 100 lb 1/14/2008 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/2002 27 Female 299 lb 3/24/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 9/30/2007 47 Female 3/17/2008 Physician United States
Primary
Concomitant
Oedema Peripheral 1/17/2007 28 Female 240 lb 2/28/2007 Consumer United States
Primary
Concomitant
Self-injurious Ideation Other Serious Male 193 lb 4/10/2008 United States
Primary
Concomitant
Vomiting Other Serious 9/30/2007 47 Female 4/18/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 5/6/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 5/9/2008 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 5/1/2007 77 Female 5/14/2008 Consumer United States
Primary
Concomitant
Sarcoma Other Serious 1/1/2007 Female 95 lb 5/22/2008 Physician United States
Primary
Concomitant
Sarcoma Other Serious 1/1/2007 Female 95 lb 5/19/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2007 Male 145 lb 5/28/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/28/2007 Female 280 lb 6/6/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/2006 53 Female 220 lb 6/13/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2007 Male 145 lb 6/25/2008 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 7/1/2008 Physician United States
Primary
Concomitant
Self-injurious Ideation Other Serious 12/1/2007 Male 193 lb 7/1/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 6/30/2008 Female 119 lb 7/9/2008 United States
Primary
Concomitant
Weight Increased Other Serious 5/12/2007 78 Female 7/15/2008 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/30/2008 55 Female 119 lb 7/16/2008 Physician United States
Primary
Concomitant
Abdominal Pain 8/8/2007 43 Female 194 lb 7/29/2008 Consumer United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 5/1/2007 77 Female 8/4/2008 Consumer United States
Primary
Concomitant
Rectal Prolapse Hospitalization 5/1/2008 39 Female 7/31/2008 Physician United States
Primary
Concomitant
Self-injurious Ideation Other Serious 12/1/2007 Male 193 lb 8/6/2008 United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 6/1/2008 55 Male 8/26/2008 Other Health Professional United States
Primary
Interacting
Weight Decreased Hospitalization 6/1/2008 Female 161 lb 8/28/2008 Consumer United States
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 7/17/2008 Male 8/28/2008 Other Health Professional Italy
Primary
Concomitant
Condition Aggravated Other Serious 38 Female 215 lb 8/22/2008 United States
Primary
Concomitant
Memory Impairment Other Serious 38 Female 215 lb 9/2/2008 Other Health Professional United States
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 7/17/2008 Female 9/23/2008 Other Health Professional Italy
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 6/1/2008 55 Male 380 lb 9/26/2008 Other Health Professional United States
Primary
Interacting
Rash 7/1/2008 35 Female 115 lb 9/16/2008 United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 10/9/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 43 Male 270 lb 10/17/2008 Consumer United States
Primary
Concomitant
Blindness Transient Other Serious 38 Male 11/11/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 12/3/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/1/2007 30 Female 190 lb 12/9/2008 United States
Primary
Concomitant
Off Label Use Other Serious 6/1/2008 26 Male 1/16/2009 Physician United States
Primary
Concomitant
Headache 10/7/2008 72 Female 2/24/2009 Consumer United States
Primary
Concomitant
Venous Thrombosis Other Serious 9/21/1999 26 Female 210 lb 4/13/2009 United States
Primary
Concomitant
Subdural Haematoma Hospitalization 9/7/2007 Female 152 lb 4/16/2009 Physician United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease 40 Female 350 lb 4/30/2009 Consumer United States
Primary
Concomitant
Interacting
Sneezing 6/5/2007 5/4/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Required Intervention 8/11/2008 Male 172 lb 4/2/2009 Consumer United States
Primary
Concomitant
Sneezing 6/5/2007 Female 137 lb 5/22/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 6/2/2009 United States
Primary
Secondary
Concomitant
Vomiting Disability 5/1/2009 45 Female 243 lb 6/9/2009 Consumer United States
Primary
Concomitant
Pain In Extremity Female 6/11/2009 United States
Primary
Concomitant
Nausea 1/1/2009 45 Female 6/5/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 6/30/2009 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 5/26/2009 40 Female 161 lb 7/8/2009 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2007 Female 100 lb 7/8/2009 United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2007 Female 100 lb 7/10/2009 United States
Primary
Concomitant
Urticaria Other Serious 5/26/2009 40 Female 161 lb 7/13/2009 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 5/17/2009 Female 7/15/2009 Consumer United States
Primary
Secondary
Interacting
Nausea Hospitalization 2/1/2009 38 Female 256 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Gingival Disorder Male 7/24/2009 Physician United States
Primary
Concomitant
Muscle Strain 6/1/2009 Female 7/27/2009 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 7/1/2008 59 Male 7/23/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2003 30 Female 236 lb 7/28/2009 United States
Primary
Concomitant
Nausea Hospitalization 2/1/2009 38 Female 256 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 8/3/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 30 Female 265 lb 8/7/2009 United States
Primary
Concomitant
Paraesthesia 7/1/2009 Male 198 lb 8/14/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/21/2003 44 Female 333 lb 8/26/2009 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 5/4/2009 Female 200 lb 9/9/2009 Consumer United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 1/1/2005 50 Female 210 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/21/2004 46 Male 350 lb 9/23/2009 United States
Primary
Concomitant
Product Substitution Issue Required Intervention 58 Male 9/26/2009 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious Female 340 lb 10/14/2009 United States
Primary
Concomitant
Vomiting Disability 5/1/2009 45 Female 243 lb 10/21/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 11/2/2009 United States
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse Hospitalization 6/24/2009 47 Female 8/29/2009 United States
Primary
Concomitant
Sarcoma Other Serious 1/1/2007 Female 95 lb 11/30/2009 Physician United States
Primary
Concomitant
Blindness Transient Other Serious 38 Male 12/1/2009 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 12/1/2008 52 Female 12/23/2009 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 43 Female 1/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 1/26/2010 United States
Primary
Secondary
Concomitant
Weight Decreased 10/1/2009 Female 96 lb 1/30/2010 Other Health Professional United States
Primary
Concomitant
Palpitations 60 Female 2/4/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 3/24/2010 United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 43 Female 3/31/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased 2/1/2010 50 Female 4/12/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 9/1/2003 68 Female 194 lb 4/16/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/3/2010 55 Female 4/23/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 4/7/2010 62 Male 271 lb 5/5/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Personality Change Other Serious 2/7/2010 74 Female 162 lb 5/21/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Skin Induration Other Serious 1/1/2004 38 Female 128 lb 5/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious Female 340 lb 5/27/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 1/1/2004 38 Female 128 lb 6/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 1/1/2004 38 Female 128 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 5/28/2010 70 Female 207 lb 6/15/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2004 38 Female 128 lb 6/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Haematoma Hospitalization 4/9/2010 59 Female 218 lb 4/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2004 38 Female 128 lb 6/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 64 Female 155 lb 6/28/2010 Consumer United States
Primary
Concomitant
Fatigue 4/18/2007 54 Male 205 lb 7/12/2010 Consumer United States
Primary
Concomitant
Tinnitus 4/1/2009 63 Female 235 lb 7/13/2010 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Dry Mouth Female 175 lb 7/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Product Substitution Issue 7/9/2010 Other Health Professional United States
Primary
Concomitant
Palpitations Other Serious 3/1/2010 60 Female 245 lb 6/21/2010 United States
Primary
Concomitant

Drug Data