Coumadin combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Haemarthrosis Hospitalization 11/1/2005 59 Female 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Interacting
Hyperkalaemia Required Intervention 1/10/2006 84 Male 144 lb 1/18/2006 Pharmacist United States
Primary
Concomitant
Cardiac Failure Other Serious 1/1/2004 Male 1/19/2006 United States
Primary
Concomitant
Rash Hospitalization 9/12/2005 73 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 7/25/2005 58 Male 2/13/2006 Consumer United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/17/2005 Female 160 lb 10/14/2005 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 2/21/2006 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 7/8/2005 81 Male 216 lb 2/23/2006 Physician United States
Primary
Concomitant
Unresponsive To Pain Stimuli Hospitalization 1/11/2006 Female 2/23/2006 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 2/14/2006 47 Male 150 lb 2/22/2006 United States
Primary
Concomitant
Vein Disorder Other Serious 9/7/2005 20 Female 121 lb 2/27/2006 Physician United States
Primary
Concomitant
Hypokinesia Death 74 Male 173 lb 3/7/2006 Physician Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 10/2/2005 84 Male 2/2/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 3/16/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 6/1/2005 58 Male 3/16/2006 Consumer United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/12/2005 46 Female 99 lb 1/17/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 3/24/2006 Physician United States
Primary
Concomitant
Scrotal Swelling Hospitalization 2/1/2006 76 Male 3/23/2006 Pharmacist United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2005 Female 3/27/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/22/2005 41 Male 170 lb 3/20/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 2/26/2001 54 Female 146 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Throat Irritation 56 Female 147 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 4/10/2006 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 4/6/2006 76 Male 283 lb 4/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 12/4/2002 75 Male 4/19/2006 Physician United States
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 12/4/2002 75 Male 4/20/2006 Physician United States
Primary
Concomitant
Atrial Tachycardia Hospitalization 10/13/2005 Female 182 lb 4/24/2006 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/2/2006 67 Male 248 lb 2/15/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1/1/2001 59 Male 285 lb 2/21/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/8/2002 56 Female 154 lb 5/3/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2001 52 Male 209 lb 5/8/2006 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization Female 197 lb 5/8/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 11/20/2005 58 Female 113 lb 11/22/2005 Pharmacist United States
Primary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/21/2005 41 Male 170 lb 5/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Mouth Haemorrhage Hospitalization 3/5/2006 84 Male 210 lb 5/16/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased 5/11/2005 90 Male 205 lb 5/30/2006 Consumer United States
Primary
Concomitant
Skin Ulcer Hospitalization Female 197 lb 6/2/2006 Physician United States
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 6/7/2006 66 Female 150 lb 6/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nausea 1/1/2006 68 Male 4/24/2006 United States
Primary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 United States
Primary
Concomitant
Skin Ulcer Life Threatening Female 197 lb 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Meningitis Death 8/1/2005 Male 250 lb 7/10/2006 Physician United States
Primary
Concomitant
Leukaemia Hospitalization 6/4/2006 61 Male 198 lb 7/5/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 3/21/2006 47 Female 155 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 3/2/2006 41 Male 214 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 4/8/2006 87 Male 5/8/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 7/5/2006 Pharmacist United States
Primary
Concomitant
Pregnancy Other Serious 10/1/2005 23 Female 7/20/2006 Physician United States
Primary
Concomitant
Skin Ulcer Life Threatening Female 197 lb 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Hospitalization 3/2/2006 41 Male 214 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Arthralgia 5/1/2005 68 Female 187 lb 8/1/2006 Consumer United States
Primary
Concomitant
Alopecia Female 8/1/2006 Consumer United States
Primary
Concomitant
Weight Decreased 87 Female 90 lb 8/1/2006 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 4/9/2006 78 Female 8/3/2006 France
Primary
Secondary
Concomitant
Flatulence 1/1/2006 Female 130 lb 8/4/2006 Physician United States
Primary
Concomitant
Diarrhoea 74 Male 156 lb 5/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 1/1/2006 68 Male 7/12/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 8/17/2005 72 Male 8/8/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 3/1/2005 63 Female 8/17/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 8/25/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 8/18/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2006 Female 88 lb 9/1/2006 Physician United States
Primary
Concomitant
Nausea 59 Female 155 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Somnolence 47 Male 253 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Stomatitis 4/1/2006 49 Male 173 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Female 7/19/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2005 Female 130 lb 9/28/2006 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 2/8/2005 43 Female 146 lb 9/27/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 10/4/2006 47 Male 130 lb 10/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/7/2006 Female 197 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Dysphonia 1/1/2005 72 Female 10/30/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 10/10/2002 63 Male 11/13/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious Female 11/13/2006 Consumer United States
Primary
Concomitant
Fatigue Female 11/13/2006 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 9/19/2006 70 Female 11/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 3/4/2005 48 Male 174 lb 11/15/2006 Pharmacist United States
Primary
Concomitant
Pancreatic Insufficiency Other Serious 9/1/2005 48 Male 134 lb 11/28/2006 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 9/19/2006 70 Female 12/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 11/22/2005 41 Male 170 lb 12/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death 12/7/2006 70 Female 12/15/2006 Consumer Canada
Primary
Concomitant
Death Death 12/6/2006 70 Female 12/19/2006 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 10/15/2006 42 Female 165 lb 1/9/2007 Consumer United States
Primary
Concomitant
Retroperitoneal Haematoma Hospitalization 9/14/2006 62 Male 217 lb 9/27/2006 United States
Primary
Concomitant
Hypertension Other Serious 6/1/2006 60 Male 274 lb 11/16/2006 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 11/22/2005 41 Male 170 lb 1/17/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Adverse Event Disability 8/28/2006 Male 138 lb 12/13/2006 Physician United States
Primary
Concomitant
Pleural Disorder Hospitalization 12/1/2006 72 Female 1/19/2007 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Disability 9/3/2006 Female 1/25/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/1/2006 Female 97 lb 4/11/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 2/26/2006 Male 245 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/6/2006 Male 145 lb 2/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo 9/3/2006 66 Female 176 lb 10/16/2006 Consumer United States
Primary
Concomitant
Localised Infection Other Serious 4/1/2006 57 Male 255 lb 1/30/2007 United States
Primary
Concomitant
Pain In Extremity 7/1/2006 59 Female 205 lb 10/16/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/2/2006 60 Male 2/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 7/12/2006 75 Female 160 lb 8/17/2006 United States
Primary
Concomitant
Vomiting Other Serious 12/1/2006 Male 169 lb 2/14/2007 Other Health Professional United States
Primary
Concomitant
Frequent Bowel Movements Other Serious 73 Female 137 lb 8/19/2005 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/1/2007 45 Female 134 lb 2/23/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/2/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/2/2006 60 Male 3/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2007 45 Female 134 lb 3/12/2007 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious Female 3/20/2007 Consumer Germany
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/6/2007 45 Female 134 lb 3/28/2007 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 8/18/2005 67 Male 238 lb 3/29/2007 Physician United States
Primary
Concomitant
Peripheral Coldness 10/11/2006 88 Female 11/7/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/1/2006 Male 169 lb 3/30/2007 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 1/20/2007 63 Male 337 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Fatigue Other Serious 1/1/2005 75 Female 4/21/2007 United States
Primary
Concomitant
Myocardial Infarction Other Serious 2/1/2007 70 Male 4/23/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 79 Female 139 lb 4/16/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 2/1/2007 70 Male 4/25/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 10/29/2006 66 Male 217 lb 1/30/2007 United States
Primary
Concomitant
Fatigue Other Serious 1/1/2005 75 Female 5/8/2007 United States
Primary
Concomitant
Skin Ulcer Hospitalization 8/2/2006 29 Female 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious Female 5/8/2007 Consumer Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2006 Male 169 lb 5/18/2007 Other Health Professional United States
Primary
Concomitant
Thermal Burn Other Serious 1/1/2006 Male 219 lb 5/22/2007 Consumer United States
Primary
Concomitant
Nausea Other Serious 79 Female 139 lb 5/24/2007 Consumer United States
Primary
Concomitant
Eye Irritation Hospitalization Male 6/4/2007 Consumer United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 1/1/2007 44 Female 109 lb 6/6/2007 Consumer United States
Primary
Concomitant
Nephrolithiasis Other Serious 4/21/2007 56 Male 6/19/2007 Physician United States
Primary
Concomitant
Nephrolithiasis Other Serious 4/21/2007 56 Male 6/19/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 10/12/2006 Male 6/26/2007 Consumer United States
Primary
Concomitant
Angioedema Other Serious 7/1/2007 Female 7/17/2007 Physician Canada
Primary
Concomitant
Catheter Related Infection Hospitalization 4/3/2007 57 Female 178 lb 7/10/2007 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/16/2007 47 Female 168 lb 7/10/2007 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 7/1/2007 73 Male 8/2/2007 United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/16/2007 Female 181 lb 7/10/2007 Other Health Professional United States
Primary
Concomitant
Medication Error 6/13/2007 57 Male 8/8/2007 United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 12/17/2006 Female 8/8/2007 Physician United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 12/17/2006 Female 8/15/2007 Physician United States
Primary
Concomitant
Angioedema Other Serious 7/1/2007 Female 8/20/2007 Physician Canada
Primary
Concomitant
Pain In Extremity Other Serious 7/26/2007 Female 112 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Sinusitis 3/1/2007 60 Female 7/11/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 11/1/2006 56 Female 9/13/2007 Consumer United States
Primary
Secondary
Concomitant
Overdose Hospitalization 6/1/2007 63 Male 9/28/2007 Consumer United States
Primary
Secondary
Concomitant
Nausea 4/9/2007 73 Male 238 lb 9/20/2007 Consumer United States
Primary
Concomitant
Osteoarthritis Hospitalization 4/1/2006 Male 10/2/2007 Consumer United States
Primary
Concomitant
Weight Decreased Death 1/1/2007 Female 160 lb 10/4/2007 Physician United States
Primary
Concomitant
Somnolence Hospitalization 5/17/2007 52 Female 9/12/2007 Consumer United States
Primary
Secondary
Concomitant

Drug Data