Coumadin combined with Provigil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Staphylococcal Infection Other Serious 12/11/2003 54 Male 190 lb 1/3/2006 Physician United States
Primary
Concomitant
Coagulopathy Hospitalization 12/14/2005 Male 228 lb 1/27/2006 Pharmacist United States
Primary
Concomitant
Skin Lesion 1/1/2004 43 Female 135 lb 2/28/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 12/11/2003 54 Male 190 lb 3/2/2006 Physician United States
Primary
Concomitant
Weight Increased Life Threatening Female 331 lb 6/23/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Fluctuation 47 Female 143 lb 8/1/2006 Consumer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 8/19/2006 55 Female 194 lb 8/31/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/11/2006 54 Male 157 lb 10/27/2006 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 10/11/2006 54 Male 157 lb 11/20/2006 Physician United States
Primary
Concomitant
No Adverse Effect 7/18/2006 82 Male 7/30/2006 Pharmacist United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 10/11/2006 54 Male 157 lb 2/12/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 10/1/2006 68 Female 3/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2007 57 Female 5/11/2007 Other Health Professional United States
Primary
Concomitant
Wheezing 9/1/2006 77 Male 160 lb 6/22/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haemorrhage Hospitalization 2/1/2007 Male 195 lb 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/6/2006 48 Female 420 lb 10/19/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/6/2006 48 Female 420 lb 10/19/2007 Consumer United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 9/12/2007 88 Female 133 lb 11/1/2007 Pharmacist United States
Primary
Concomitant
Visual Disturbance Other Serious 9/6/2006 48 Female 420 lb 11/20/2007 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/6/2006 48 Female 420 lb 11/20/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 9/1/2006 Female 420 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2001 53 Female 140 lb 12/18/2007 Physician United States
Primary
Concomitant
Thrombosis Other Serious 11/1/2007 59 Female 2/7/2008 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 3/1/2006 72 Male 1/16/2008 Physician United States
Primary
Concomitant
Thrombosis Other Serious 11/1/2007 59 Female 3/4/2008 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 1/24/2008 67 Female 195 lb 3/31/2008 Consumer United States
Primary
Concomitant
Small Cell Carcinoma Hospitalization 11/14/2007 56 Male 188 lb 4/22/2008 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2008 58 Male 5/13/2008 Other Health Professional United States
Primary
Concomitant
No Therapeutic Response Death 5/1/2008 57 Male 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pathological Gambling 1/1/2002 Male 209 lb 6/10/2008 Consumer United States
Primary
Concomitant
Pyrexia 5/2/2008 Female 7/3/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 10/3/2007 93 Female 115 lb 7/15/2008 United States
Primary
Concomitant
Urosepsis Hospitalization 3/12/2008 49 Female 7/18/2008 United States
Primary
Concomitant
International Normalised Ratio Increased 6/12/2007 85 Male 165 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Epistaxis Male 7/29/2008 Consumer United States
Primary
Interacting
Haemorrhage 1/1/2000 7/29/2008 Lawyer United States
Primary
Interacting
Condition Aggravated Other Serious 38 Female 215 lb 8/22/2008 United States
Primary
Concomitant
Memory Impairment Other Serious 38 Female 215 lb 9/2/2008 Other Health Professional United States
Primary
Concomitant
Insomnia 4/30/2008 72 Female 9/23/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 Male 237 lb 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Urine Odour Abnormal 12/27/2007 Female 12/1/2008 Physician United States
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 11/5/2007 56 Male 187 lb 12/15/2008 Other Health Professional United States
Primary
Concomitant
Tinnitus Other Serious 1/1/1999 51 Male 251 lb 1/26/2009 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 3/1/2006 72 Male 1/20/2009 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/1999 51 Male 251 lb 2/19/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 2/1/2009 51 Female 147 lb 5/5/2009 United States
Primary
Concomitant
Nasopharyngitis Hospitalization 1/1/2003 42 Female 101 lb 5/28/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 6/2/2009 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 10/11/2006 54 Male 157 lb 6/8/2009 United States
Primary
Concomitant
Pain In Extremity Female 6/11/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 6/30/2009 United States
Primary
Secondary
Concomitant
Prothrombin Level Decreased 7/22/2009 Physician United States
Primary
Interacting
Weight Decreased 5/1/2009 67 Male 216 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 12/8/2004 86 Female 100 lb 7/29/2009 United States
Primary
Concomitant
Wound Secretion Hospitalization 1/1/2003 67 Female 194 lb 7/29/2009 Physician United States
Primary
Concomitant
Prothrombin Level Decreased 7/22/2009 Physician United States
Primary
Interacting
Weight Decreased 5/1/2009 67 Male 216 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 5/17/2009 Male 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 8/3/2009 United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 5/17/2009 Male 8/13/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 Female 8/13/2009 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 66 Female 231 lb 8/13/2009 Pharmacist United States
Primary
Concomitant
Nausea 3/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Wound Secretion Hospitalization 1/1/2003 67 Female 194 lb 9/10/2009 Physician United States
Primary
Concomitant
Nausea Other Serious 7/3/2009 Female 226 lb 9/23/2009 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 5/17/2009 Male 9/28/2009 Physician United States
Primary
Secondary
Concomitant
Scleroderma Hospitalization 10/1/2006 68 Female 9/28/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 11/2/2009 United States
Primary
Secondary
Concomitant
Renal Cyst Other Serious 1/1/2009 67 Male 11/18/2009 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 6/24/2009 47 Female 8/29/2009 United States
Primary
Concomitant
Rash Erythematous Hospitalization 1/1/2004 Male 198 lb 12/7/2009 Consumer United States
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 11/5/2007 56 Male 187 lb 12/7/2009 Physician United States
Primary
Concomitant
Calcinosis Hospitalization 1/1/2004 Male 198 lb 12/15/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 12/23/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 1/26/2010 United States
Primary
Secondary
Concomitant
Sensory Loss Required Intervention 1/18/2010 70 Male 170 lb 1/25/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 59 Female 191 lb 1/20/2010 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 59 Female 191 lb 2/5/2010 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 10/10/2008 Female 180 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased 4/1/2007 Female 140 lb 3/8/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/11/2010 51 Female 345 lb 3/3/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 2/7/2009 Female 180 lb 3/9/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 55 Female 170 lb 3/24/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2006 Female 3/24/2010 Consumer United States
Primary
Concomitant
Paranoia 9/23/2009 Female 3/16/2010 Pharmacist United States
Primary
Concomitant
Vein Disorder Other Serious 8/1/2003 Female 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 1/1/2008 Female 269 lb 3/31/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/7/2009 58 Female 180 lb 4/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/1999 60 Female 4/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 64 Male 150 lb 5/14/2010 United States
Primary
Secondary
Concomitant
Rash Hospitalization 69 Female 242 lb 5/13/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/10/2010 69 Female 242 lb 5/24/2010 Pharmacist United States
Primary
Concomitant
Incoherent Hospitalization 4/1/2010 72 Female 6/1/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 64 Male 150 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Klebsiella Infection Hospitalization 6/9/2010 53 Female 146 lb 6/30/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 7/12/2010 United States
Primary
Secondary
Concomitant
Fatigue 4/18/2007 54 Male 205 lb 7/12/2010 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/23/2010 67 Female 7/22/2010 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization Female 7/23/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Stress Hospitalization 7/19/2010 53 Female 8/5/2010 United States
Primary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 8/25/2010 United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Diarrhoea 3/14/2010 59 Male 346 lb 8/28/2010 United States
Primary
Concomitant
Flushing 10/1/2009 66 Female 180 lb 8/29/2010 United States
Primary
Concomitant
Product Substitution Issue Other Serious 7/23/2010 53 Female 180 lb 8/30/2010 Physician United States
Primary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 9/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2009 48 Male 258 lb 10/4/2010 Consumer United States
Primary
Concomitant
Vein Disorder Other Serious 8/1/2003 66 Female 10/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 10/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/1999 60 Female 10/12/2010 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 48 Female 10/14/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 8/1/2010 63 Female 10/18/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 10/22/2010 United States
Primary
Secondary
Concomitant
Tremor Other Serious 9/6/2006 48 Female 421 lb 10/28/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2009 48 Male 258 lb 11/11/2010 Physician United States
Primary
Concomitant
Tremor Hospitalization 7/19/2010 53 Female 139 lb 11/15/2010 Other Health Professional United States
Primary
Concomitant
Renal Cyst Other Serious 10/1/2009 67 Male 11/24/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 9/6/2006 48 Female 420 lb 11/29/2010 Consumer United States
Primary
Secondary
Concomitant
Haemoglobin Increased Other Serious Male 269 lb 12/7/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 1/1/2010 52 Female 139 lb 12/8/2010 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 1/1/2010 66 Female 180 lb 11/30/2010 United States
Primary
Concomitant
Tremor Other Serious 1/1/2010 52 Female 139 lb 12/17/2010 Other Health Professional United States
Primary
Concomitant
Device Related Sepsis Hospitalization 11/30/2010 54 Female 12/21/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 9/6/2006 48 Female 420 lb 12/29/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2010 52 Female 139 lb 12/31/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 64 Male 150 lb 12/31/2010 United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/1/2000 51 Male 237 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 1/1/2000 51 Male 237 lb 1/21/2011 United States
Primary
Secondary
Concomitant
Tremor Other Serious 8/1/2006 48 Female 420 lb 1/24/2011 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal Other Serious 12/1/2010 52 Female 2/9/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pain Other Serious 6/5/2008 18 Female 130 lb 2/21/2011 Consumer United States
Primary
Secondary
Concomitant
Headache Hospitalization 1/7/2008 64 Male 2/28/2011 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Abnormal Other Serious 12/1/2010 52 Female 3/1/2011 Pharmacist United States
Primary
Secondary
Concomitant
Bone Lesion Hospitalization 9/23/2003 66 Female 3/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Subcutaneous Hospitalization 1/7/2008 64 Male 3/18/2011 Other Health Professional United States
Primary
Concomitant
Fluid Overload Hospitalization 12/27/2010 90 Male 3/30/2011 Physician United States
Primary
Concomitant
Nausea Other Serious 1/1/2011 76 Male 3/28/2011 Consumer United States
Primary
Concomitant
Flushing Hospitalization 1/7/2008 64 Male 4/11/2011 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/1/2010 50 Male 270 lb 4/12/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/11/2011 56 Female 141 lb 6/1/2011 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2011 34 Female 240 lb 5/19/2011 Pharmacist United States
Primary
Concomitant
Hemiparesis Hospitalization 1/7/2008 64 Male 6/8/2011 Other Health Professional United States
Primary
Concomitant
Skin Induration Hospitalization 1/1/2005 57 Male 6/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 2/25/2002 63 Female 6/23/2011 Physician United States
Primary
Secondary
Concomitant
Facial Pain Other Serious 1/1/2000 51 Male 237 lb 6/27/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data