Coumadin combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myalgia Hospitalization 12/1/2001 Male 174 lb 1/6/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 4/1/2005 80 Male 175 lb 2/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/19/2006 77 Male 215 lb 4/12/2006 Physician United States
Primary
Concomitant
Ill-defined Disorder Hospitalization 2/6/2006 82 207 lb 3/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 4/11/2006 86 Male 4/20/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/1/2006 76 Male 194 lb 5/4/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/1/2005 67 Male 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 8/12/2005 67 Male 2/17/2006 Other Health Professional United States
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Repair Other Serious 1/1/2004 76 Female 147 lb 5/5/2006 United States
Primary
Secondary
Concomitant
Tremor Other Serious 59 Female 107 lb 3/15/2006 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 9/1/2005 75 Male 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Death 4/1/2006 80 Male 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Hospitalization 11/13/2006 Male 137 lb 11/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/1/2006 68 Female 11/21/2006 Physician United States
Primary
Concomitant
Mouth Haemorrhage Death 8/4/2005 47 Male 11/22/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Death 5/4/2005 Female 155 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 11/1/2006 79 Male 198 lb 12/11/2006 Physician United States
Primary
Concomitant
Torsade De Pointes Life Threatening 9/9/2006 60 Male 275 lb 11/6/2006 Pharmacist United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2006 Male 180 lb 12/19/2006 United States
Primary
Concomitant
Muscle Spasms Hospitalization 8/3/2006 Male 137 lb 12/28/2006 Physician United States
Primary
Concomitant
Melaena Hospitalization 8/30/2006 56 Male 192 lb 11/4/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 1/18/2006 74 Male 1/2/2007 Pharmacist United States
Primary
Concomitant
Hypertension Hospitalization 1/1/2002 73 Female 140 lb 9/29/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 80 Male 203 lb 1/8/2007 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 9/15/2006 78 Female 186 lb 9/20/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 80 Male 203 lb 1/13/2007 United States
Primary
Concomitant
Lactic Acidosis Hospitalization 12/1/2006 58 Female 139 lb 1/17/2007 Consumer United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 1/18/2007 United States
Primary
Secondary
Concomitant
Retinal Artery Occlusion Hospitalization 11/1/2004 30 Male 1/19/2007 Consumer United States
Primary
Concomitant
Nightmare Other Serious 1/4/2007 Male 215 lb 1/19/2007 Consumer United States
Primary
Concomitant
Erectile Dysfunction 69 Male 11/1/2006 United States
Primary
Concomitant
Weight Decreased 1/1/2006 72 Male 265 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pleural Effusion Other Serious 12/27/2005 75 Female 142 lb 2/15/2007 Physician Canada
Primary
Concomitant
Pleural Effusion Other Serious 11/20/2006 76 Female 142 lb 2/15/2007 Physician Canada
Primary
Concomitant
Anaphylactic Reaction Other Serious 2/8/2007 52 Male 256 lb 2/16/2007 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/1/2007 55 Male 176 lb 2/23/2007 Consumer United States
Primary
Concomitant
Pleural Effusion Other Serious 12/27/2005 75 Female 151 lb 2/27/2007 Physician Canada
Primary
Concomitant
Pleural Effusion Other Serious 11/20/2006 76 Female 151 lb 2/27/2007 Physician Canada
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/28/2007 55 Male 176 lb 3/2/2007 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 12/13/2006 89 Male 126 lb 3/1/2007 Pharmacist United States
Primary
Concomitant
Weight Fluctuation Death 2/10/2007 63 Male 140 lb 3/5/2007 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 3/10/2007 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/6/2006 55 Male 176 lb 3/12/2007 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious Female 3/20/2007 Consumer Germany
Primary
Concomitant
Papillary Thyroid Cancer Hospitalization 8/10/2006 Male 205 lb 3/27/2007 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2005 62 Male 3/27/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 2/11/2007 61 Male 3/28/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/16/2006 55 Male 176 lb 3/28/2007 Consumer United States
Primary
Concomitant
Stomach Discomfort Other Serious 8/1/2006 72 Male 260 lb 11/28/2006 United States
Primary
Concomitant
Haemoptysis Hospitalization 8/1/2006 74 Male 190 lb 3/29/2007 Consumer United States
Primary
Concomitant
Rash Papular Hospitalization 12/16/2006 Male 198 lb 3/30/2007 Consumer
Primary
Concomitant
Urticaria Other Serious 1/20/2007 63 Male 337 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 3/29/2007 Physician Canada
Primary
Concomitant
Eye Disorder Other Serious 3/16/2007 Female 4/11/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/16/2006 55 Male 176 lb 4/17/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/24/2006 82 Female 128 lb 3/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 4/5/2007 66 Male 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/1/2007 56 Male 148 lb 4/17/2007 Physician Canada
Primary
Concomitant
Chills Other Serious 4/24/2007 29 Male 280 lb 4/26/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 3/18/2006 Male 146 lb 4/26/2007
Primary
Concomitant
Infusion Site Extravasation Other Serious 3/15/2007 70 Female 5/1/2007 Pharmacist Canada
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 5/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Disorder Hospitalization 4/14/2007 73 Male 5/3/2007 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious Female 5/8/2007 Consumer Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/2/2006 42 Male 254 lb 5/9/2007 Consumer United States
Primary
Concomitant
Cerebral Atrophy Other Serious 9/1/2006 Female 119 lb 5/10/2007 Consumer United States
Primary
Concomitant
Paralysis Other Serious 5/3/2007 45 Female 380 lb 5/14/2007 United States
Primary
Concomitant
Pulmonary Oedema Other Serious 3/1/2007 73 Female 5/14/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 4/5/2007 66 Male 5/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Heart Rate Irregular Other Serious 11/1/2006 85 Female 5/23/2007 United States
Primary
Concomitant
Ear Haemorrhage Hospitalization 8/5/2005 80 Female 180 lb 12/13/2006 United States
Primary
Secondary
Concomitant
Chills Other Serious 4/24/2007 29 Male 280 lb 5/25/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/2/2007 88 Female 4/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/1/2006 85 Female 6/1/2007 United States
Primary
Concomitant
Haemoptysis Hospitalization 8/1/2006 74 Male 190 lb 6/1/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 3/1/2007 78 Female 6/7/2007 Consumer United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/1/2003 56 Male 6/7/2007 Physician United States
Primary
Concomitant
Blood Glucose Increased 3/30/2007 81 Female 5/17/2007 United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 6/2/2007 69 Female 120 lb 6/10/2007 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Other Serious 6/7/2007 Male 328 lb 6/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2007 73 Male 6/14/2007 Consumer United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 4/1/2006 64 Male 209 lb 6/15/2007 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 5/30/2007 Female 161 lb 6/21/2007 United States
Primary
Concomitant
Psychomotor Hyperactivity 87 Female 118 lb 6/22/2007 United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 3/1/2007 48 Female 118 lb 6/26/2007 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Required Intervention 3/15/2007 63 Female 211 lb 6/13/2007 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 6/28/2007 Physician Canada
Primary
Concomitant
Pancreatic Insufficiency Other Serious 5/3/2007 45 Female 380 lb 7/6/2007 Physician United States
Primary
Concomitant
Thrombosis Hospitalization 6/20/2007 82 Female 148 lb 7/17/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Other Serious 4/5/2007 66 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 7/18/2007 Physician Canada
Primary
Concomitant
Treatment Noncompliance Hospitalization 2/1/2007 36 Male 7/25/2007 Consumer United States
Primary
Concomitant
Chest Pain 5/1/2007 Female 7/26/2007 Consumer United States
Primary
Concomitant
Haemoptysis Hospitalization 8/1/2006 74 Male 190 lb 7/27/2007 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/9/2007 Female 123 lb 7/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/18/2007 Male 167 lb 7/31/2007 Physician United States
Primary
Concomitant
Skin Cancer Other Serious 7/1/2007 73 Male 8/2/2007 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 8/6/2007 Physician United States
Primary
Concomitant
Syncope Hospitalization 6/18/2006 74 Male 8/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Streptococcal Bacteraemia Hospitalization 7/18/2007 Male 167 lb 8/9/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 6/25/2006 Female 8/15/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/18/2007 Male 167 lb 8/16/2007 Physician United States
Primary
Concomitant
Haemoptysis Hospitalization 8/1/2006 74 Male 190 lb 8/21/2007 Consumer United States
Primary
Concomitant
Angioedema Other Serious 7/1/2007 Female 8/20/2007 Physician Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2006 Male 167 lb 8/22/2007 Pharmacist United States
Primary
Concomitant
Epistaxis 1/1/2005 67 Male 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/1/2007 78 Female 116 lb 9/4/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 8/1/2006 74 Male 190 lb 9/6/2007 Consumer United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 8/1/2006 74 Male 190 lb 9/7/2007 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 8/19/2007 Female 189 lb 9/10/2007 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/1/2007 78 Female 116 lb 9/11/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 8/19/2007 Female 189 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/1/2006 85 Female 9/13/2007 United States
Primary
Concomitant
Back Pain 8/24/2006 Female 161 lb 9/20/2007 Consumer United States
Primary
Concomitant
Back Pain 9/19/2006 40 Male 430 lb 9/20/2007 Consumer United States
Primary
Concomitant
Urinary Incontinence 10/4/2006 68 Female 203 lb 9/20/2007 Consumer United States
Primary
Concomitant
Headache 12/8/2006 81 Male 134 lb 9/20/2007 Consumer United States
Primary
Concomitant
Back Pain 67 Male 163 lb 9/20/2007 Consumer United States
Primary
Concomitant
Vomiting 4/24/2007 Male 227 lb 9/20/2007 Consumer United States
Primary
Concomitant
Back Pain 5/31/2007 56 Male 201 lb 9/20/2007 Consumer United States
Primary
Concomitant
Rash 6/6/2007 Male 9/20/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 189 lb 12/19/2007 Physician United States
Primary
Concomitant
Erectile Dysfunction 1/1/2006 78 Male 12/20/2007 Pharmacist United States
Primary
Concomitant
Throat Irritation 7/18/2007 85 Male 12/20/2007 Consumer United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 12/10/2007 Female 131 lb 1/22/2008 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased 69 Female 175 lb 4/18/2008 Other Health Professional United States
Primary
Concomitant
Urosepsis 2/18/2005 56 Male 4/20/2005 Physician United States
Primary
Concomitant
Nausea 2/28/2008 58 Female 245 lb 4/17/2008 Physician United States
Primary
Concomitant
Life Support Death 5/10/2008 Male 191 lb 6/2/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 11/24/2007 76 Female 137 lb 6/17/2008 United States
Primary
Concomitant
Pericarditis Hospitalization 10/16/2007 65 Female 250 lb 6/9/2008 United States
Primary
Concomitant
Pruritus Generalised 75 Male 7/1/2008 Consumer United States
Primary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 Female 148 lb 7/3/2008 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 12/1/2007 64 Male 231 lb 7/29/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/19/2008 56 Female 8/7/2008 Pharmacist Colombia
Primary
Concomitant
Obstructive Airways Disorder Other Serious 66 Male 8/8/2007 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 8/12/2008 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 Female 148 lb 8/13/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/1/2008 70 Male 131 lb 8/26/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 85 Female 105 lb 9/2/2008 United States
Primary
Secondary
Concomitant
Heart Rate Increased Life Threatening 88 Female 95 lb 9/18/2008 Physician United States
Primary
Concomitant
Haemoglobin Decreased 9/1/2008 Female 250 lb 12/12/2008 United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/4/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 7/14/1988 Female 182 lb 2/5/2009 United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 4/1/2008 84 Female 2/1/2009 United States
Primary
Concomitant
Impacted Fracture Hospitalization 6/27/2008 52 Male 2/12/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 1/1/2008 Male 2/12/2009 Physician United States
Primary
Concomitant
Peritonitis Hospitalization 11/4/2008 47 Male 154 lb 1/16/2009 United States
Primary
Secondary
Concomitant

Drug Data