Coumadin combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 8/24/2002 73 Male 260 lb 1/23/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 8/24/2002 73 Male 260 lb 1/24/2006 Physician United States
Primary
Concomitant
Injury Death 8/26/2004 73 Female 99 lb 2/14/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2000 53 Male 300 lb 2/15/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/23/2004 75 Male 185 lb 2/17/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 79 Female 115 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Hypertension Hospitalization 7/1/2004 67 Male 2/21/2006 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 9/9/2005 62 Male 225 lb 11/28/2005 Pharmacist United States
Primary
Secondary
Concomitant
Blood Glucose Increased 1/1/2006 Male 2/27/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 8/24/2002 73 Male 260 lb 2/28/2006 Physician United States
Primary
Concomitant
Seasonal Allergy Hospitalization 7/1/2004 67 Male 196 lb 3/2/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 1/26/2006 56 Male 187 lb 3/6/2006 Physician United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 7/1/2000 63 Male 185 lb 3/8/2006 Physician United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2005 76 Female 170 lb 3/10/2006 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 8/24/2002 73 Male 260 lb 3/20/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Required Intervention 2/18/2006 75 Female 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/24/2002 73 Male 260 lb 3/23/2006 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 2/1/2006 62 Female 218 lb 3/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/1/2005 62 Male 326 lb 1/20/2006 United States
Primary
Concomitant
Tooth Disorder Other Serious 3/1/2006 Female 180 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 1/1/2005 Female 1/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/7/2006 Other Health Professional Canada
Primary
Concomitant
International Normalised Ratio Increased 12/15/2005 67 Male 1/20/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2006 62 Female 218 lb 3/30/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/24/2002 73 Male 260 lb 4/17/2006 Physician United States
Primary
Concomitant
Dry Mouth Male 2/7/2006 United States
Primary
Concomitant
Varicose Vein Other Serious 1/1/2005 Female 4/10/2006 United States
Primary
Concomitant
Diabetes Mellitus Other Serious Male 268 lb 4/11/2006 United States
Primary
Secondary
Concomitant
Diabetes Mellitus Other Serious 10/1/2004 62 Male 268 lb 4/11/2006 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/1/1999 41 Male 291 lb 4/25/2006 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 7/1/2000 60 Male 185 lb 4/26/2006 Physician United States
Primary
Concomitant
Macular Degeneration Other Serious Male 4/27/2006 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/27/2006 Other Health Professional Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 79 Female 115 lb 5/1/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/24/2002 73 Male 260 lb 5/1/2006 Physician United States
Primary
Concomitant
Wound Hospitalization 6/21/2000 67 Male 190 lb 5/3/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2005 Female 4/26/2006 Physician United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 8/1/2005 64 Male 2/17/2006 Physician United States
Primary
Concomitant
Fall Hospitalization 2/21/2006 74 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Macular Degeneration Other Serious Male 165 lb 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/23/2004 75 Male 185 lb 5/18/2006 Lawyer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious Male 165 lb 5/19/2006 Consumer United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 5/4/2006 50 Female 5/19/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 1/26/2006 56 Male 187 lb 6/6/2006 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 1/26/2006 56 Male 187 lb 5/30/2006 Physician United States
Primary
Secondary
Concomitant
Medical Device Complication Other Serious Male 165 lb 6/7/2006 Consumer United States
Primary
Secondary
Concomitant
Medication Error Life Threatening 6/1/2006 61 Male 6/5/2006 Other Health Professional United States
Primary
Concomitant
Prothrombin Level Decreased Other Serious 1/10/2000 75 Male 6/14/2006 Canada
Primary
Secondary
Concomitant
Nausea Hospitalization 10/7/2005 54 Female 6/19/2006 Physician United States
Primary
Concomitant
Prothrombin Level Decreased Other Serious 1/25/2000 74 Male 6/21/2006 Canada
Primary
Secondary
Concomitant
Nausea 2/6/2006 63 Female 343 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/6/2006 65 Male 230 lb 4/17/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Death 4/1/2006 80 Male 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Injection Site Bruising 11/29/2005 61 Male 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 74 Male 196 lb 4/17/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Abnormal 12/1/2005 54 Female 190 lb 4/17/2006 Consumer United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 3/1/2006 Female 180 lb 7/10/2006 Consumer United States
Primary
Secondary
Concomitant
Overdose Hospitalization 4/8/2006 87 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Rash 5/29/2005 67 Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 Male 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased 39 Female 7/21/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 8/1/2005 61 Male 192 lb 8/1/2006 Consumer United States
Primary
Concomitant
Muscle Tightness 1/1/2006 67 Female 174 lb 8/1/2006 Consumer United States
Primary
Concomitant
Wolff-parkinson-white Syndrome Other Serious 1/1/2006 58 Female 220 lb 7/27/2006 United States
Primary
Secondary
Concomitant
Blindness Other Serious 63 Male 190 lb 8/23/2006 Consumer United States
Primary
Concomitant
Localised Infection Required Intervention 6/1/2006 75 Male 8/17/2006 Canada
Primary
Concomitant
Tooth Abscess 4/11/2006 70 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Wolff-parkinson-white Syndrome Other Serious 1/1/2006 58 Female 220 lb 9/8/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Decreased Life Threatening 9/28/2006 72 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Renal Infarct Other Serious 7/6/2006 54 Female 175 lb 12/20/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 9/28/2006 72 Female 141 lb 1/16/2007 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Fluctuation Hospitalization 12/18/2006 70 Male 163 lb 1/22/2007 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Disability 9/3/2006 Female 1/25/2007 Consumer United States
Primary
Concomitant
Weight Decreased 7/12/2006 77 Male 160 lb 10/16/2006 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 10/1/2005 53 Male 243 lb 2/12/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 9/8/2006 70 Male 216 lb 10/16/2006 Consumer United States
Primary
Concomitant
Ileus Hospitalization 1/12/2007 55 Male 236 lb 3/6/2007 Physician United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 1/1/2007 47 Female 296 lb 5/29/2007 United States
Primary
Concomitant
Rash Generalised 3/28/2007 75 Male 5/17/2007 United States
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 1/1/2007 47 Female 296 lb 6/12/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/11/2007 60 Male 6/28/2007 Consumer United States
Primary
Concomitant
Unevaluable Event Disability Male 7/5/2007 Pharmacist United States
Primary
Concomitant
Death Disability 3/1/2007 80 Female 90 lb 7/9/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Sensation Of Heaviness Hospitalization 7/15/2007 54 Female 7/31/2007 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Hospitalization 7/15/2007 54 Female 291 lb 9/26/2007 Physician United States
Primary
Concomitant
Wheezing Other Serious 5/30/2007 Female 133 lb 9/28/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 6/25/2007 Female 249 lb 9/20/2007 Consumer United States
Primary
Concomitant
Renal Infarct Other Serious 7/6/2006 54 Female 175 lb 10/16/2007 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 10/2/2007 73 Male 211 lb 10/16/2007 Physician United States
Primary
Concomitant
Vertigo Hospitalization 1/1/2007 66 Male 10/22/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 78 Male 10/26/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 5/30/2007 Female 133 lb 11/2/2007 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/28/2007 64 Male 229 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 9/1/2007 65 Female 165 lb 1/28/2008 Physician United States
Primary
Concomitant
Blood Test Abnormal 11/6/2007 74 Male 2/15/2008 United States
Primary
Concomitant
Nasal Congestion 1/1/2008 64 Male 3/17/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Bruising Female 3/14/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 1/1/2006 66 Female 3/14/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2008 78 Female 6/2/2008 United States
Primary
Concomitant
Renal Disorder Other Serious 9/1/2007 Female 233 lb 6/13/2008 Physician United States
Primary
Concomitant
Vomiting 6/19/2007 56 Male 6/23/2008 Other Health Professional United States
Primary
Concomitant
Nasal Congestion 1/1/2008 64 Male 7/14/2008 Other Health Professional United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization 7/13/2008 Female 190 lb 7/23/2008 Consumer United States
Primary
Concomitant
Weight Increased 4/1/2007 70 Male 7/24/2008 Consumer United States
Primary
Concomitant
Hyperhidrosis Hospitalization 4/27/2008 49 Male 280 lb 8/7/2008 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 7/4/2008 Female 178 lb 8/22/2008 Physician United States
Primary
Concomitant
Death Death 50 Female 8/22/2008 Pharmacist Canada
Primary
Concomitant
Procedural Pain Hospitalization 7/1/2008 Female 8/20/2008 Consumer United States
Primary
Concomitant
Palpitations Other Serious 1/1/2008 63 Female 297 lb 8/22/2008 United States
Primary
Concomitant
Sepsis Hospitalization 3/1/2008 70 Male 131 lb 8/26/2008 Physician United States
Primary
Concomitant
Pancreatic Carcinoma Metastatic Death 1/1/2007 Male 9/4/2008 Physician United States
Primary
Concomitant
Pyrexia Other Serious 3/1/2008 51 Female 198 lb 10/1/2008 Physician United States
Primary
Secondary
Concomitant
Gallbladder Disorder Hospitalization 9/9/2008 61 Male 10/15/2008 Consumer United States
Primary
Concomitant
Photopsia Other Serious Male 160 lb 10/16/2008 Consumer United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 9/9/2008 61 Male 10/23/2008 Consumer United States
Primary
Concomitant
Renal Pain 11/28/2008 79 Female 11/28/2008 Pharmacist United States
Primary
Concomitant
Pleuritic Pain 12/1/2008 Female 1/15/2009 Consumer
Primary
Concomitant
Tremor 5/5/2008 68 Female 110 lb 1/13/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2005 Male 280 lb 1/16/2009 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 1/20/2009 Female 1/30/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 11/16/2008 Male 182 lb 2/2/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/6/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/12/2009 United States
Primary
Secondary
Concomitant
Oedema Hospitalization 12/10/2006 44 Male 239 lb 2/23/2009 Pharmacist United States
Primary
Concomitant
Respiratory Failure Death 2/6/2009 Male 270 lb 3/4/2009 Consumer United States
Primary
Concomitant
Night Sweats 9/22/2008 70 Male 174 lb 3/6/2009 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 2/21/2009 Male 153 lb 3/9/2009 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious Female 125 lb 3/16/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 3/12/2009 United States
Primary
Concomitant
Subdural Haematoma Other Serious 11/1/2008 Male 212 lb 3/24/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/22/2008 Male 194 lb 3/24/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization Female 132 lb 3/26/2009 Consumer United States
Primary
Concomitant
Somnolence Other Serious 1/30/2009 Male 3/27/2009 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious 9/21/1999 26 Female 210 lb 4/13/2009 United States
Primary
Concomitant
Unevaluable Event Death 71 Male 5/28/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 5/6/2009 65 Male 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 5/1/2009 60 Male 6/16/2009 United States
Primary
Secondary
Vomiting Hospitalization 7/2/2009 Male 195 lb 7/10/2009 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/25/2009 79 Male 7/17/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 3/18/2009 56 Female 258 lb 7/17/2009 United States
Primary
Concomitant
Oral Pain Hospitalization 6/1/2009 Female 160 lb 7/27/2009 Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2003 30 Female 236 lb 7/28/2009 United States
Primary
Concomitant
International Normalised Ratio Fluctuation 58 Male 284 lb 7/22/2009 Consumer United States
Primary
Concomitant
Polypectomy Other Serious 6/1/2009 57 Female 280 lb 7/30/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/2/2009 Male 195 lb 7/31/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Thyroidectomy Hospitalization 8/1/2008 Female 8/5/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Decreased Male 8/11/2009 Consumer
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant

Drug Data