Coumadin combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 2/12/2006 Female 205 lb 3/1/2006 Other Health Professional United States
Primary
Concomitant
Central Line Infection Hospitalization 8/19/2004 61 Male 154 lb 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 2/12/2006 Female 205 lb 3/20/2006 Other Health Professional United States
Primary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Tremor Hospitalization 1/1/2003 52 Female 295 lb 4/21/2006 Physician United States
Primary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 4/24/2006 Other Health Professional Italy
Primary
Concomitant
Rash Other Serious 1/4/2005 85 Male 180 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 5/15/2006 64 Male 284 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Death 2/12/2006 70 Female 205 lb 6/13/2006 Other Health Professional United States
Primary
Concomitant
Rash Hospitalization 5/29/2006 81 Male 243 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Rash Erythematous 1/1/2005 88 Female 110 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 1/1/2005 74 Male 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Epistaxis 3/1/2005 68 Male 190 lb 8/1/2006 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/22/2005 74 Male 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 1/1/2005 68 Female 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
Diarrhoea 1/1/2005 77 Female 220 lb 8/1/2006 Consumer United States
Primary
Concomitant
Diabetes Mellitus 3/1/2005 38 Female 265 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 11/22/2005 80 Male 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 69 Male 218 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 11/15/2005 74 Male 183 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 1/1/2005 Female 8/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 73 Female 139 lb 8/1/2006 Consumer United States
Primary
Concomitant
Thyroid Neoplasm 1/1/2006 75 Male 8/1/2006 Consumer United States
Primary
Concomitant
Interacting
Abdominal Discomfort 3/29/2006 Female 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 72 Female 185 lb 8/1/2006 Consumer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2003 52 Female 295 lb 8/7/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/1/2006 37 Female 227 lb 9/19/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/7/2006 77 Male 236 lb 10/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Muscular Weakness Disability 12/1/2006 70 Female 2/22/2007 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Disability 12/1/2006 70 Female 4/4/2007 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 7/13/2008 Female 220 lb 10/10/2008 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/1/2008 Male 10/18/2008 Physician Italy
Primary
Concomitant
Pancreatic Carcinoma Metastatic Death 1/1/2007 Male 10/24/2008 Physician United States
Primary
Concomitant
Night Sweats 9/22/2008 70 Male 174 lb 10/30/2008 Consumer United States
Primary
Concomitant
Herpes Virus Infection Other Serious 9/29/2008 Male 11/11/2008 Physician United States
Primary
Secondary
Concomitant
Transfusion Hospitalization 5/6/2009 Male 6/5/2009 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 5/1/2009 82 Male 6/4/2009 Physician United States
Primary
Secondary
Concomitant
Skin Laceration 4/2/2009 Female 202 lb 6/15/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 3/1/2009 Male 197 lb 6/15/2009 Consumer United States
Primary
Concomitant
Photosensitivity Reaction 4/1/2009 Male 6/15/2009 Physician United States
Primary
Concomitant
Volvulus Hospitalization 1/1/2008 Female 270 lb 7/14/2009 Other Health Professional United States
Primary
Concomitant
Tinnitus Hospitalization 51 Male 7/21/2009 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 68 Male 183 lb 9/21/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2008 71 Female 179 lb 9/29/2009 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 65 Male 9/22/2009 United States
Primary
Concomitant
Vomiting Hospitalization 62 Male 267 lb 9/25/2009 United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Sinus Rhythm Hospitalization 62 Female 9/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2009 Female 280 lb 10/12/2009 Consumer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 8/25/2009 Male 309 lb 10/16/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 6/1/2009 59 Male 10/19/2009 Other Health Professional United States
Primary
Concomitant
Medication Error Male 1/6/2010 United States
Primary
Concomitant
Eructation 75 Male 1/4/2010 Consumer United States
Primary
Concomitant
Vomiting 10/25/2009 72 Female 1/4/2010 Consumer United States
Primary
Concomitant
Urticaria 43 Male 270 lb 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Gastric Ulcer Hospitalization 8/10/2009 79 Male 120 lb 2/18/2010 Consumer Taiwan, Province Of China
Primary
Secondary
Concomitant
Ureteric Obstruction Hospitalization 3/14/2008 66 Male 2/5/2010 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Ureteric Obstruction Hospitalization 3/14/2008 66 Male 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Nausea Hospitalization 76 Female 2/26/2010 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2010 76 Female 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2010 76 Female 3/2/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Partial Seizures Hospitalization 2/10/2010 53 Male 253 lb 3/1/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/2/2010 59 Female 3/9/2010 Consumer Colombia
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/22/2009 Male 266 lb 3/16/2010 Other Health Professional United States
Primary
Concomitant
Yellow Skin Death 11/1/2009 Male 3/17/2010 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/3/2010 Female 3/17/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 10/1/2006 59 Male 297 lb 3/17/2010 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/29/2010 Female 210 lb 3/22/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/23/2010 62 Male 203 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Implantable Defibrillator Insertion Other Serious 1/1/2009 62 Male 5/13/2010 Consumer United States
Primary
Concomitant
Infection Other Serious 3/1/2010 67 Male 5/17/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious Male 5/17/2010 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Male 217 lb 5/17/2010 United States
Primary
Concomitant
Small Intestinal Perforation Hospitalization 60 Female 285 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Hospitalisation Hospitalization 5/10/2010 66 Male 5/20/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious Male 5/27/2010 Consumer United States
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 71 Male 6/23/2010 Consumer France
Primary
Secondary
Concomitant
Skin Burning Sensation Hospitalization Female 168 lb 9/10/2010 Consumer United States
Primary
Concomitant
Retinal Vascular Disorder Other Serious 1/1/2009 69 Male 185 lb 11/2/2010 Consumer Brazil
Primary
Concomitant
Interacting
Osteoarthritis Hospitalization 69 Male 185 lb 12/8/2010 Physician Brazil
Primary
Concomitant
Neuropathy Peripheral Other Serious 5/19/2009 76 Female 191 lb 2/14/2011 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2010 70 Male 2/17/2011 Consumer Brazil
Primary
Concomitant
Pituitary Tumour Benign Other Serious 1/16/2008 35 Female 163 lb 4/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 1/11/2011 63 Female 208 lb 5/3/2011 Physician United States
Primary
Secondary
Concomitant
Atrial Thrombosis Other Serious 57 6/9/2011 Other Health Professional Brazil
Primary
Concomitant
Pain Other Serious 9/13/1999 53 Male 161 lb 6/10/2011 Lawyer United States
Primary
Concomitant
Thyroid Cancer Other Serious Female 6/8/2011 Physician United States
Primary
Concomitant
Stress Other Serious 4/3/2008 83 Male 180 lb 8/22/2011 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 12/1/2010 74 Female 170 lb 8/22/2011 Physician United States
Primary
Concomitant
Left Ventricular Hypertrophy Other Serious 3/25/2009 72 Female 146 lb 9/11/2011 United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/11/2011 63 Female 208 lb 9/15/2011 Physician United States
Primary
Secondary
Concomitant
Overdose Hospitalization 4/28/2011 70 Male 149 lb 9/8/2011 Pharmacist United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 5/8/2011 83 Female 152 lb 9/12/2011 Pharmacist United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/10/2011 10/7/2011 Physician Israel
Primary
Concomitant
Myocardial Infarction Hospitalization 3/10/2010 63 Female 223 lb 10/7/2011 United States
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 1/1/2011 81 Male 10/5/2011 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Hospitalization 10/5/2011 65 Male 187 lb 10/17/2011 Consumer Brazil
Primary
Concomitant
Aortic Aneurysm Other Serious 9/15/2011 69 Male 169 lb 10/17/2011 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 6/4/2011 69 Male 10/18/2011 Physician United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 10/7/2011 83 Male 11/16/2011 Physician Italy
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 11/15/2011 83 Male 150 lb 11/24/2011 Pharmacist United States
Primary
Concomitant
Drug Ineffective 12/14/2011 70 Male 265 lb 1/24/2012 Physician United States
Primary
Concomitant
Pathological Fracture Other Serious Female 1/25/2012 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/1/2010 65 Male 207 lb 1/30/2012 Consumer Brazil
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2012 56 Female 224 lb 3/9/2012 Pharmacist United States
Primary
Concomitant
Iron Deficiency Anaemia Other Serious Male 221 lb 3/16/2012 Consumer United States
Primary
Concomitant
Implant Site Infection Hospitalization 1/1/2007 43 Female 3/19/2012 Consumer United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 8/10/2009 79 Male 120 lb 4/6/2012 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Back Pain Death 1/1/2011 75 Male 176 lb 6/8/2012 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/22/2012 83 Female 6/27/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/22/2012 83 Female 7/3/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Hair Texture Abnormal Other Serious 1/1/2012 66 Female 7/13/2012 Other Health Professional United States
Primary
Concomitant
Confusional State Other Serious 6/23/2012 78 Female 7/16/2012 Physician Italy
Primary
Concomitant
Dizziness 6/1/2011 82 Male 192 lb 7/18/2012 Consumer United States
Primary
Concomitant
Epistaxis Other Serious 6/19/2011 82 Male 123 lb 7/18/2012 Consumer United States
Primary
Concomitant
Eye Haemorrhage Other Serious 67 Male 7/18/2012 Consumer United States
Primary
Concomitant
Dysgeusia 81 Male 7/18/2012 Consumer United States
Primary
Concomitant
Pain In Extremity 66 Female 7/18/2012 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged 1/1/2011 72 Male 218 lb 7/18/2012 Consumer United States
Primary
Concomitant
Interacting
Rash 10/15/2011 68 Male 7/18/2012 Pharmacist United States
Primary
Concomitant
Dyspnoea 1/1/2011 67 Female 7/18/2012 Consumer France
Primary
Secondary
Concomitant
International Normalised Ratio Abnormal 11/13/2004 45 Female 170 lb 7/18/2012 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 3/1/2012 86 Female 7/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/1/2011 71 Male 220 lb 7/18/2012 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 5/10/2011 68 Female 7/18/2012 Physician United States
Primary
Concomitant
Skin Fissures 72 Male 207 lb 7/18/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral 61 Male 236 lb 7/18/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious Male 7/18/2012 Lawyer United States
Primary
Concomitant
Chest Pain Hospitalization 4/1/2010 7/18/2012 Physician United States
Primary
Secondary
Concomitant
Knee Operation Hospitalization 7/2/2012 53 Male 288 lb 7/19/2012 Other Health Professional United States
Primary
Concomitant
Walking Aid User Hospitalization 9/1/2003 70 Male 165 lb 7/6/2012 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization Male 7/26/2012 Physician United States
Primary
Concomitant
Haemothorax Hospitalization 6/18/2012 63 Male 225 lb 7/13/2012 United States
Primary
Concomitant
Hypoaesthesia Other Serious Male 7/27/2012 Physician United States
Primary
Concomitant
Pain Other Serious 11/5/2007 34 Female 230 lb 7/29/2012 Consumer United States
Primary
Secondary
Concomitant
Constipation Hospitalization 6/28/2012 75 Male 7/30/2012 Consumer France
Primary
Concomitant
Blood Pressure Systolic Increased Other Serious 6/23/2012 78 Female 7/30/2012 Other Health Professional Italy
Primary
Concomitant
Psychomotor Retardation Hospitalization 7/19/2012 65 Female 7/31/2012 Physician Italy
Primary
Secondary
Concomitant
Wound Other Serious Female 8/1/2012 Lawyer United States
Primary
Concomitant
Pruritus Hospitalization Male 8/1/2012 Consumer United States
Primary
Concomitant

Drug Data