Coumadin combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 59 Male 1/26/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 1/22/2006 Female 280 lb 1/26/2006 United States
Primary
Secondary
Concomitant
Death Death 59 Male 345 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Central Line Infection Hospitalization 8/19/2004 61 Male 154 lb 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/26/2004 65 Female 370 lb 5/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 59 Male 346 lb 5/20/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 74 Male 6/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 2/9/2006 Male 4/17/2006 Consumer United States
Primary
Concomitant
Malaise Hospitalization 5/10/2006 79 Female 7/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 9/14/2006 52 Female 161 lb 10/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/1/2005 Male 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/1/2005 Male 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 11/8/2006 73 Male 183 lb 12/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/10/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/1/2005 Female 12/13/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/8/2006 74 Male 183 lb 12/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Death 5/4/2005 Female 155 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/8/2006 74 Male 12/11/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/7/2006 Female 12/27/2006 Physician United States
Primary
Secondary
Concomitant
X-ray Gastrointestinal Tract Abnormal Hospitalization 11/8/2006 74 Male 12/19/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/8/2006 74 Male 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/24/2005 70 Male 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 1/15/2007 Other Health Professional
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 1/22/2007 Other Health Professional
Primary
Secondary
Concomitant
Syncope Hospitalization 1/2/2007 Female 126 lb 2/5/2007 Other Health Professional
Primary
Secondary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 2/10/2007 Lawyer United States
Primary
Concomitant
Oral Intake Reduced Hospitalization 1/2/2007 Female 126 lb 2/14/2007 Other Health Professional
Primary
Secondary
Concomitant
Syncope Hospitalization 1/18/2007 Female 126 lb 2/14/2007 Other Health Professional
Primary
Secondary
Concomitant
Syncope Other Serious 1/18/2007 Female 126 lb 2/19/2007 Other Health Professional
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 2/22/2007 Other Health Professional
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 2/26/2007 Physician United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 2/23/2007 Other Health Professional
Primary
Secondary
Concomitant
Dermatitis Acneiform 70 Male 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 2/17/2007 Male 3/5/2007 Physician Canada
Primary
Secondary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 3/12/2007 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization Unknown 3/8/2007 Other Health Professional United States
Primary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 3/28/2007 Lawyer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/14/2005 Male 210 lb 3/28/2007 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/8/2006 Male 183 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/15/2005 82 Female 113 lb 4/6/2007 Physician United States
Primary
Concomitant
Palpitations Other Serious 7/12/2006 Male 4/17/2007 Physician
Primary
Concomitant
Sepsis Life Threatening 1/24/2007 Female 112 lb 4/27/2007 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2007 52 Male 4/27/2007 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Other Serious 2/17/2007 Male 5/14/2007 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/2/2007 Male 149 lb 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/29/2006 54 Female 2/28/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 1/24/2007 Female 112 lb 6/28/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 7/6/2007 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 4/11/2007 Female 145 lb 7/9/2007 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 7/12/2007 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 6/19/2007 53 Female 139 lb 7/19/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/19/2007 53 Female 139 lb 7/20/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Death 7/23/2007 Male 159 lb 8/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 8/20/2007 Physician United States
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Death 7/23/2007 Male 159 lb 8/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/3/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/3/2007 Physician United States
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Death 7/23/2007 Male 159 lb 9/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 7/23/2007 Male 159 lb 9/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2007 Male 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/30/2007 66 Male 194 lb 11/19/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 11/5/2007 Female 190 lb 11/6/2007 United States
Primary
Secondary
Concomitant
Localised Infection Hospitalization 8/27/2006 Female 12/6/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 12/7/2006 Female 115 lb 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Other Serious 7/9/2007 Male 159 lb 12/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 1/7/2008 Lawyer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/13/2007 Male 2/6/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 2/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 1/15/2008 Female 150 lb 2/6/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/6/2008 Female 2/25/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/6/2008 Female 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 2/27/2008 Male 205 lb 3/5/2008 United States
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Hospitalization 2/18/2008 41 Male 243 lb 3/24/2008 Consumer United States
Primary
Secondary
Concomitant
Gallbladder Perforation Hospitalization 4/11/2007 Female 145 lb 4/4/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 144 lb 4/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/29/2006 54 Female 2/28/2008 Physician United States
Primary
Concomitant
Cholecystitis Hospitalization 4/11/2007 Female 145 lb 5/20/2008 Physician United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 5/24/2008 Male 185 lb 6/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 5/24/2008 Male 185 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/7/2006 Female 115 lb 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Life Threatening 5/24/2008 Male 185 lb 6/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 10/29/2007 Male 4/28/2008 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 7/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 6/2/2008 74 Female 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/14/2008 Male 8/4/2008 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 7/4/2008 Female 178 lb 8/22/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 7/14/2008 Male 9/4/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 10/24/2007 85 Male 157 lb 9/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/9/2007 Male 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Sinusitis Life Threatening 7/23/2007 Male 10/8/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/31/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 11/5/2007 Female 190 lb 11/10/2008 United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 12/15/2008 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 11/18/2008 53 Male 12/17/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 2/26/2005 Male 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 12/24/2008 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 12/31/2008 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 11/17/2008 Male 1/6/2009 Physician United States
Primary
Concomitant
Arrhythmia Death 1/1/2009 Female 190 lb 2/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/23/2001 Female 178 lb 2/13/2009 Lawyer United States
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 11/17/2008 Male 2/24/2009 Physician United States
Primary
Concomitant
Peritonitis Life Threatening 1/18/2007 Female 126 lb 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Anal Ulcer Hospitalization 3/30/2009 Female 139 lb 6/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 7/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 66 Female 7/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 66 Female 7/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 3/8/2007 Female 8/3/2009 Physician United States
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 3/11/2009 Female 136 lb 8/11/2009 Other Health Professional Canada
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 3/8/2007 Female 8/14/2009 Physician United States
Primary
Secondary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/17/2009 Other Health Professional Canada
Primary
Concomitant
Lymphoma Other Serious 7/1/2009 66 Male 210 lb 8/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 8/31/2005 Male 175 lb 9/4/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 12/3/2009 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 7/22/2009 Male 224 lb 2/5/2010 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 2/17/2010 Male 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Arrhythmia Death 1/1/2009 81 Female 190 lb 4/22/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 11/20/2003 61 Female 140 lb 5/18/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization Female 275 lb 6/8/2010 Consumer United States
Primary
Concomitant
Eyelid Ptosis Hospitalization 1/15/2011 79 Female 159 lb 1/21/2011 Physician United States
Primary
Secondary
Concomitant
Ligament Injury Hospitalization 11/29/2006 47 Female 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Bone Lesion Other Serious 11/29/2006 47 Female 7/29/2011 Physician United States
Primary
Secondary
Concomitant
Night Sweats Other Serious 11/29/2006 47 Female 160 lb 8/8/2011 Physician United States
Primary
Secondary
Concomitant
Fluid Retention Other Serious 4/1/2010 61 Female 180 lb 8/9/2011 Consumer United States
Primary
Concomitant
Angiopathy Other Serious 2/1/2011 62 Female 180 lb 8/11/2011 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 2/1/2011 62 Female 180 lb 8/25/2011 Consumer United States
Primary
Concomitant
Left Atrial Dilatation Other Serious 11/23/2001 52 Female 178 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Leukocytosis Other Serious 1/1/2005 64 Male 179 lb 11/2/2011 Physician United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 11/29/2006 47 Female 160 lb 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Plasma Protein Metabolism Disorder Other Serious Male 11/24/2011 Physician United States
Primary
Secondary
Concomitant
Angiopathy Other Serious 11/23/2001 52 Female 178 lb 12/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 11/29/2006 47 Female 160 lb 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 11/29/2006 47 Female 160 lb 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Melaena Other Serious 12/1/2011 64 Female 1/31/2012 Consumer Italy
Primary
Concomitant
Anaemia Other Serious 12/1/2011 64 Female 2/7/2012 Physician Italy
Primary
Concomitant
Anaemia Other Serious 12/1/2011 64 Female 2/13/2012 Physician Italy
Primary
Concomitant
Dysphonia Other Serious 1/1/2011 62 Female 180 lb 2/28/2012 Physician United States
Primary
Concomitant
Hypocoagulable State Other Serious 12/27/2009 78 Female 4/6/2012 Pharmacist Italy
Primary
Secondary
Concomitant
Hypocoagulable State Hospitalization 1/26/2012 79 Female 4/10/2012 Consumer Italy
Primary
Concomitant
Anaemia Hospitalization 1/26/2012 79 Female 4/18/2012 Physician Italy
Primary
Concomitant
Balance Disorder Other Serious Female 148 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Cardiac Tamponade Hospitalization 4/11/2012 72 Female 161 lb 5/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/1/2009 65 Female 5/15/2012 Consumer Italy
Primary
Concomitant
Sepsis Other Serious 12/27/2009 78 Female 5/22/2012 Consumer Italy
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 12/27/2009 78 Female 5/30/2012 Consumer Italy
Primary
Secondary
Concomitant

Drug Data