Coumadin combined with Letairis

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Other Serious 7/21/2007 62 Male 8/2/2007 Consumer
Primary
Concomitant
Pain In Extremity Other Serious 7/26/2007 Female 112 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Pruritus Disability 7/1/2007 Female 163 lb 9/12/2007 Consumer United States
Primary
Concomitant
Drug Hypersensitivity Other Serious 8/12/2007 Female 9/28/2007 Physician United States
Primary
Concomitant
Oedema Hospitalization 9/1/2007 Male 255 lb 9/28/2007 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization Male 220 lb 10/4/2007 Pharmacist United States
Primary
Concomitant
Throat Tightness Other Serious 8/10/2007 Male 220 lb 10/11/2007 Pharmacist United States
Primary
Concomitant
Ocular Icterus Other Serious 8/26/2007 Male 10/16/2007 Pharmacist United States
Primary
Concomitant
Drug Hypersensitivity Other Serious 8/12/2007 Female 10/22/2007 Physician United States
Primary
Concomitant
Oedema Hospitalization 80 Male 10/22/2007 United States
Primary
Concomitant
Vomiting Other Serious 8/12/2007 Female 11/19/2007 Physician United States
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 9/5/2007 Female 197 lb 12/7/2007 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 12/1/2007 Female 170 lb 12/17/2007 Other Health Professional United States
Primary
Concomitant
Throat Tightness Other Serious Female 128 lb 12/19/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 11/26/2007 Female 12/21/2007 Consumer United States
Primary
Concomitant
Nasal Congestion Other Serious 8/16/2007 Female 126 lb 12/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 12/1/2007 Female 170 lb 1/3/2008 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious Female 250 lb 1/8/2008 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 8/1/2007 Male 1/11/2008 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization Female 190 lb 1/14/2008 Pharmacist United States
Primary
Concomitant
Haemorrhage Hospitalization 12/25/2007 Female 190 lb 1/14/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/17/2007 Female 170 lb 1/15/2008 Other Health Professional United States
Primary
Concomitant
Renal Impairment Life Threatening 12/10/2007 Female 168 lb 1/17/2008 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 8/1/2007 Male 1/17/2008 Physician United States
Primary
Concomitant
Sinusitis Other Serious Female 189 lb 1/17/2008 Physician United States
Primary
Concomitant
Thrombosis Life Threatening 10/22/2007 Female 159 lb 1/18/2008 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/1/2007 Male 204 lb 1/24/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 12/27/2007 Male 216 lb 1/24/2008 Consumer United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 1/17/2007 Female 170 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 180 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Telangiectasia Life Threatening 12/21/2007 Female 190 lb 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/28/2007 Male 204 lb 1/30/2008 Physician United States
Primary
Concomitant
Death Death 1/4/2008 Female 147 lb 1/30/2008 Other Health Professional United States
Primary
Concomitant
Blood Potassium Increased Other Serious 1/3/2008 Female 148 lb 1/30/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/17/2007 Female 170 lb 1/31/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 1/31/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/1/2007 Female 180 lb 1/31/2008 Other Health Professional United States
Primary
Concomitant
Death Death 1/16/2008 Male 2/1/2008 Physician United States
Primary
Concomitant
Presyncope Other Serious Male 290 lb 2/4/2008 Pharmacist United States
Primary
Concomitant
Cardiac Arrest Death 12/29/2007 Female 147 lb 2/5/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 12/17/2007 Female 170 lb 2/5/2008 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/28/2007 Male 204 lb 2/7/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 2/8/2008 Consumer United States
Primary
Concomitant
Oedema Hospitalization Female 170 lb 2/11/2008 Other Health Professional United States
Primary
Concomitant
Death Other Serious 1/3/2008 Female 148 lb 2/12/2008 Other Health Professional United States
Primary
Concomitant
Death Other Serious 1/3/2008 Female 148 lb 2/15/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 1/16/2008 Male 2/15/2008 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/5/2008 Male 234 lb 2/15/2008 Physician United States
Primary
Concomitant
Death Death 1/1/2008 Female 2/18/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 2/14/2008 Male 2/25/2008 Consumer United States
Primary
Concomitant
Prothrombin Time Abnormal Other Serious 9/5/2007 Female 197 lb 2/25/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Hospitalization 2/14/2008 Male 2/29/2008 Consumer United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/12/2008 Pharmacist United States
Primary
Concomitant
Rash Other Serious Male 212 lb 3/12/2008 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious Female 143 lb 3/13/2008 Pharmacist United States
Primary
Concomitant
Blindness Unilateral Other Serious 2/23/2008 Female 106 lb 3/17/2008 Physician United States
Primary
Concomitant
Nasopharyngitis Male 3/17/2008 Consumer United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/18/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 12/1/2007 Male 3/24/2008 Consumer United States
Primary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/25/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Death Female 132 lb 3/25/2008 Pharmacist United States
Primary
Concomitant
Oedema Peripheral 11/13/2007 Male 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Hypocoagulable State Hospitalization Female 192 lb 3/28/2008 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/5/2008 Male 234 lb 4/4/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 2/14/2008 Male 4/10/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization Male 4/15/2008 Pharmacist United States
Primary
Concomitant
Palpitations Other Serious 1/15/2008 Female 4/17/2008 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Hospitalization Female 170 lb 4/18/2008 Physician United States
Primary
Concomitant
Haemorrhage Other Serious Male 262 lb 4/22/2008 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/28/2007 Male 204 lb 4/28/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 10/10/2007 Female 250 lb 4/30/2008 Physician United States
Primary
Concomitant
Anaemia Hospitalization Female 208 lb 5/1/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious Male 262 lb 5/1/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious Female 5/1/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 4/5/2008 Female 240 lb 5/1/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 4/20/2008 Female 106 lb 5/1/2008 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 3/28/2008 Female 261 lb 5/2/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 11/1/2007 68 Female 232 lb 5/9/2008 Consumer United States
Primary
Concomitant
Death Death Male 5/20/2008 Pharmacist United States
Primary
Concomitant
Melaena Other Serious 3/28/2008 Male 262 lb 5/23/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 4/26/2008 Female 5/29/2008 Consumer United States
Primary
Concomitant
Nausea Other Serious Male 148 lb 5/29/2008 Consumer United States
Primary
Concomitant
Central Line Infection Hospitalization 1/16/2008 64 Male 5/30/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Death 3/1/2008 Male 6/2/2008 Physician United States
Primary
Concomitant
Palpitations Disability Female 180 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Infection Hospitalization Female 58 lb 6/18/2008 Consumer United States
Primary
Concomitant
Arrhythmia Other Serious Female 6/20/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 5/18/2008 6/23/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 4/26/2008 Female 6/26/2008 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 6/4/2008 Female 175 lb 6/27/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious Female 6/27/2008 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 9/1/2007 Male 255 lb 7/1/2008 Consumer United States
Primary
Concomitant
Anaemia Other Serious Male 7/2/2008 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 9/17/2007 Female 7/2/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious Female 7/8/2008 Pharmacist United States
Primary
Concomitant
Palpitations Disability Female 180 lb 7/8/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 6/4/2008 Female 175 lb 7/9/2008 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Death 6/30/2008 Female 7/10/2008 Pharmacist United States
Primary
Concomitant
Blood Count Abnormal Hospitalization Male 7/11/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/11/2008 Female 7/11/2008 Physician United States
Primary
Concomitant
Palpitations Hospitalization Female 7/22/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 6/21/2008 Female 301 lb 7/22/2008 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 4/7/2008 Female 165 lb 7/25/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2007 Male 255 lb 7/28/2008 Consumer United States
Primary
Concomitant
Splenic Rupture Life Threatening 6/18/2008 Male 160 lb 7/30/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/14/2008 Female 95 lb 7/30/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 6/21/2008 Female 301 lb 7/30/2008 Physician United States
Primary
Concomitant
Nausea Other Serious Female 148 lb 7/30/2008 Consumer United States
Primary
Concomitant
Anaemia Other Serious Male 7/31/2008 Physician United States
Primary
Concomitant
Clostridium Difficile Colitis Other Serious 6/27/2008 Female 175 lb 8/4/2008 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Death 6/30/2008 Female 8/7/2008 Physician United States
Primary
Concomitant
Blood Count Abnormal Hospitalization Male 8/11/2008 Physician United States
Primary
Concomitant
Arthralgia Other Serious 7/1/2008 Female 8/12/2008 Consumer United States
Primary
Concomitant
Death Death Female 166 lb 8/18/2008 Physician United States
Primary
Concomitant
Dry Mouth Disability 8/5/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Fluid Retention Other Serious 12/19/2007 Female 9/3/2008 Physician United States
Primary
Concomitant
Splenic Rupture Life Threatening 6/18/2008 Male 160 lb 9/3/2008 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 8/5/2008 Female 120 lb 9/12/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 9/5/2008 Male 260 lb 9/23/2008 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 8/27/2008 Female 9/23/2008 Consumer United States
Primary
Concomitant
Subdural Haematoma Hospitalization Male 9/25/2008 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization Female 179 lb 9/25/2008 Physician United States
Primary
Concomitant
Death Death Male 148 lb 9/25/2008 Consumer United States
Primary
Concomitant
Cough Hospitalization 9/18/2008 Female 290 lb 9/26/2008 Consumer United States
Primary
Concomitant
Pulmonary Congestion Hospitalization 7/14/2008 Female 95 lb 10/2/2008 Consumer United States
Primary
Concomitant
Death Death Female 107 lb 10/6/2008 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/22/2008 Male 236 lb 10/7/2008 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Bacterial Other Serious 9/30/2008 Female 10/10/2008 Consumer United States
Primary
Concomitant
Blood Potassium Decreased Hospitalization Female 83 lb 10/10/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/4/2008 Female 117 lb 10/10/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization Female 107 lb 10/10/2008 Consumer United States
Primary
Concomitant
Central Line Infection Hospitalization Female 113 lb 10/10/2008 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious Female 150 lb 10/14/2008 Physician United States
Primary
Concomitant
Splenic Rupture Other Serious 6/18/2008 Male 201 lb 10/15/2008 Physician United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/22/2008 Male 236 lb 10/16/2008 Physician United States
Primary
Concomitant
Swelling Face Other Serious 8/27/2008 Female 10/16/2008 Physician United States
Primary
Concomitant
Photopsia Other Serious Male 160 lb 10/16/2008 Consumer United States
Primary
Concomitant
Traumatic Haemorrhage Hospitalization 9/15/2008 Female 10/17/2008 Consumer United States
Primary
Secondary
Chest Pain Hospitalization Female 194 lb 10/21/2008 Consumer United States
Primary
Concomitant
Pregnancy Other Serious Female 10/22/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/13/2008 72 Male 10/22/2008 Lawyer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 8/5/2008 Female 120 lb 10/22/2008 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 8/5/2008 Female 120 lb 10/27/2008 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious Female 10/27/2008 Physician United States
Primary
Concomitant
Photopsia Other Serious Male 160 lb 10/28/2008 Consumer United States
Primary
Concomitant
Swelling Other Serious Female 10/31/2008 Physician United States
Primary
Concomitant
Pregnancy Other Serious Female 11/4/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death 10/31/2008 Female 79 lb 11/4/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 124 lb 11/4/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 10/5/2008 Female 11/4/2008 Consumer United States
Primary
Secondary
Concomitant

Drug Data