Coumadin combined with Isosorbide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Deep Vein Thrombosis Death 2/1/2004 54 Male 236 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 79 Female 115 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Vertigo Other Serious 1/1/2000 78 Male 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Drug Ineffective 80 Female 134 lb 2/24/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 80 Female 134 lb 3/7/2006 Consumer United States
Primary
Concomitant
Urinary Tract Disorder Hospitalization 1/1/2003 74 Male 231 lb 3/7/2006 Physician United States
Primary
Concomitant
Drug Ineffective 80 Female 134 lb 3/9/2006 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Death 2/1/2004 54 Male 236 lb 3/30/2006 Lawyer United States
Primary
Concomitant
Swelling Other Serious 1/1/2004 62 Female 143 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Tooth Disorder Other Serious 3/1/2006 Female 180 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 4/11/2006 88 Female 77 lb 4/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 42 Female 201 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Syncope Hospitalization 12/1/1999 Male 280 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Heart Rate Decreased Required Intervention 1/1/2000 83 Male 4/11/2006 United States
Primary
Secondary
Concomitant
Rash 11/3/2005 92 Male 1/25/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 79 Female 115 lb 5/1/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 7/1/2005 80 Female 160 lb 3/2/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 5/10/2005 73 Female 162 lb 5/25/2006 Physician United States
Primary
Concomitant
Pain Of Skin 2/8/2006 62 Male 4/24/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 5/10/2005 73 Female 162 lb 6/21/2006 Physician United States
Primary
Concomitant
Bladder Spasm 1/1/2006 82 Female 200 lb 7/6/2006 Consumer United States
Primary
Concomitant
High Density Lipoprotein Decreased Other Serious 3/1/2006 Female 180 lb 7/10/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 5/10/2005 73 Female 162 lb 7/14/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/19/2006 62 Female 7/21/2006 Consumer United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 73 Female 8/24/2006 Other Health Professional United States
Primary
Concomitant
Throat Irritation Other Serious 10/1/2005 73 Female 185 lb 8/30/2006 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Hospitalization 7/26/2006 79 Male Pharmacist United States
Primary
Concomitant
Somnolence 3/1/2006 96 Female 7/31/2006 Consumer United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 5/18/2006 81 Male 237 lb 10/30/2006 Physician United States
Primary
Concomitant
Somnolence 54 Male 11/13/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 72 Male 265 lb 10/16/2006 Consumer United States
Primary
Concomitant
Walking Aid User Other Serious 12/12/2006 51 Female 140 lb 5/11/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 8/1/2006 87 Male 120 lb 5/21/2007 Consumer United States
Primary
Concomitant
Malaise Death 6/30/2007 84 Male 188 lb 8/1/2008 United States
Primary
Concomitant
Hyperhidrosis Hospitalization 4/27/2008 49 Male 280 lb 8/7/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 8/18/2008 Consumer United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2008 93 Male 8/20/2008 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 4/1/2006 53 Male 239 lb 8/29/2008 Lawyer United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 1/1/2008 78 Female 10/31/2008 Consumer United States
Primary
Concomitant
Joint Injury Hospitalization 11/12/2007 86 Male 2/26/2009 Physician Italy
Primary
Secondary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 3/6/2009 Consumer
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/9/2009 Physician United States
Primary
Concomitant
Epistaxis Hospitalization 4/1/2008 79 Male 3/18/2009 Other Health Professional United States
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/26/2009 Physician United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 3/30/2009 Physician
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 1/1/2005 72 Female 139 lb 3/31/2009 Physician United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 8/10/2000 57 Male 344 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/1/2006 57 Male 4/13/2009 Lawyer United States
Primary
Concomitant
Hernia Hospitalization 69 Male 146 lb 5/7/2009 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 5/30/2007 Male 5/15/2009 Physician United States
Primary
Secondary
Concomitant
Skin Induration Death 10/1/2002 77 Female 187 lb 5/26/2009 Physician United States
Primary
Concomitant
Skin Induration Death 10/1/2002 77 Female 187 lb 5/26/2009 Physician United States
Primary
Concomitant
Skin Induration Death 10/1/2002 77 Female 187 lb 5/29/2009 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 6/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Purple Glove Syndrome Hospitalization 11/3/2008 78 Female 161 lb 6/4/2009 Pharmacist United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 6/12/2009 Physician
Primary
Secondary
Concomitant
Photosensitivity Reaction 4/1/2009 Male 6/15/2009 Physician United States
Primary
Concomitant
Subcutaneous Nodule Death 10/1/2002 77 Female 187 lb 6/17/2009 Physician United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2007 Male 296 lb 7/6/2009 Physician United States
Primary
Concomitant
Unevaluable Event Death 65 Female 155 lb 7/10/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/9/2007 Male 174 lb 7/21/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 168 lb 7/22/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2009 56 Female 258 lb 7/17/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 296 lb 7/31/2009 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 Female 8/3/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 80 Female 8/3/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/5/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 65 Female 155 lb 8/24/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 50 Male 8/31/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/31/2009 United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 9/3/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/4/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 9/4/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 9/8/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 9/10/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/10/2009 United States
Primary
Concomitant
Hypotension Other Serious 1/1/2009 Male 9/23/2009 Consumer United States
Primary
Concomitant
Surgery Hospitalization 78 Female 9/17/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 64 Female 155 lb 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 81 Female 9/23/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 9/24/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 51 Female 9/25/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 9/28/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Neuropathy Peripheral 1/1/2007 Female 10/6/2009 Consumer
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/12/2009 United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 10/9/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 51 Female 10/9/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 10/17/2009 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Pain In Extremity Hospitalization 72 Male 10/20/2009 United States
Primary
Concomitant
Neuropathy Peripheral 1/1/2007 Female 10/29/2009 Consumer
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 10/26/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/4/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 72 Male 11/4/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 4/5/2008 60 Female 11/4/2009 United States
Primary
Concomitant
Paraesthesia Hospitalization 5/27/2005 58 Male 195 lb 11/4/2009 United States
Primary
Concomitant
Weight Decreased Other Serious Male 11/9/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 66 Male 11/10/2009 Consumer United States
Primary
Concomitant
Flushing Male 11/25/2009 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 11/16/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/16/2009 United States
Primary
Concomitant
Photodermatosis Hospitalization 72 Male 11/18/2009 United States
Primary
Concomitant
Ulcer Hospitalization 67 Male 11/20/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 11/18/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 73 Male 11/17/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 63 Female 11/18/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 81 Female 11/18/2009 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 64 Female 155 lb 11/20/2009 United States
Primary
Concomitant
Skin Laceration Hospitalization 11/9/2009 51 Female 12/3/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 296 lb 12/1/2009 Physician United States
Primary
Concomitant
Injection Site Haematoma Hospitalization 1/1/2005 Male 280 lb 12/1/2009 Consumer United States
Primary
Concomitant
Rash Erythematous Hospitalization 1/1/2004 Male 198 lb 12/7/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 61 Male 12/1/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Wound Secretion Hospitalization Male 12/1/2009 Lawyer United States
Primary
Concomitant
Photodermatosis Hospitalization 72 Male 12/1/2009 United States
Primary
Concomitant
Visual Impairment 3/31/2008 Female 128 lb 12/15/2009 Physician
Primary
Concomitant
Calcinosis Hospitalization 1/1/2004 Male 198 lb 12/15/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Photodermatosis Hospitalization 57 Male 12/10/2009 United States
Primary
Concomitant
Joint Swelling 91 Female 126 lb 12/22/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 12/23/2009 Lawyer United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/23/2009 Lawyer United States
Primary
Concomitant
Tremor Hospitalization 9/11/2009 66 Male 262 lb 12/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/1/2009 Male 1/4/2010 Physician United States
Primary
Concomitant
Tenderness Other Serious 12/2/2009 77 Female 156 lb 1/8/2010 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment 3/31/2008 Female 128 lb 1/14/2010 Physician
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 66 Male 1/7/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 61 Male 236 lb 1/11/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 1/11/2010 United States
Primary
Concomitant
Dyspnoea Death 84 Male 139 lb 1/26/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 8/1/2009 Male 1/28/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 64 Female 1/21/2010 Lawyer United States
Primary
Concomitant
Drug Dispensing Error 8/9/2009 Male 2/1/2010 Physician United States
Primary
Concomitant

Drug Data