Coumadin combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperkalaemia Hospitalization 10/7/2005 70 Male 191 lb 10/12/2005 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2004 84 Male 130 lb 4/11/2005 Consumer United States
Primary
Secondary
Concomitant
Cough Other Serious 2/21/2006 54 Male 181 lb 2/24/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/1999 77 Male 231 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Rash Pruritic Other Serious 3/1/2005 75 Male 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 7/19/2006 62 Female 214 lb 8/23/2006 Consumer United States
Primary
Concomitant
Infusion Site Pain Other Serious 1/1/2005 64 Male 142 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 6/16/2004 82 Male 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/1/2006 87 Male 120 lb 6/5/2007 Consumer United States
Primary
Concomitant
Walking Aid User Other Serious 12/12/2006 51 Female 140 lb 6/13/2007 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 8/1/2000 Male 225 lb 6/28/2007
Primary
Concomitant
Weight Decreased 6/1/2006 Male 145 lb 7/26/2007 Consumer United States
Primary
Concomitant
Muscular Weakness 86 Female 8/3/2007 Consumer United States
Primary
Concomitant
Muscle Haemorrhage Hospitalization 12/30/2006 Male 214 lb 5/1/2007 Pharmacist United States
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/4/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 8/28/2007 Male 9/4/2007 Consumer United States
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/18/2007 Consumer United States
Primary
Concomitant
Yellow Skin Other Serious 4/5/2006 87 Male 1/31/2007 Physician United States
Primary
Concomitant
Back Pain 8/24/2006 Female 161 lb 9/20/2007 Consumer United States
Primary
Concomitant
Stomatitis 7/4/2007 86 Female 10/26/2007 Consumer United States
Primary
Concomitant
Visual Disturbance 80 Female 10/26/2007 Consumer United States
Primary
Concomitant
Pleural Effusion 10/9/2007 United States
Primary
Concomitant
Prostatic Specific Antigen Increased Male 11/13/2007 Consumer United States
Primary
Concomitant
Viral Infection 9/14/2006 66 Male 11/13/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/13/2007 Male 160 lb 11/20/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea 67 Female 11/29/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/1/2000 81 Male 185 lb 12/6/2007 Consumer United States
Primary
Concomitant
Pollakiuria Male 12/20/2007 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Hospitalization 8/10/2007 71 Female 1/3/2008 Pharmacist United States
Primary
Concomitant
Ascites Other Serious 63 Female 180 lb 2/22/2008 United States
Primary
Concomitant
Scratch Hospitalization 3/6/2007 Male 220 lb 6/27/2007 Pharmacist United States
Primary
Concomitant
Dyspnoea 67 Female 3/6/2008 Consumer United States
Primary
Concomitant
Headache Death 5/17/2007 77 Male 3/5/2008 Consumer United States
Primary
Secondary
Concomitant
Ascites Other Serious 9/1/2007 63 Female 233 lb 3/20/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 4/28/2008 United States
Primary
Concomitant
Visual Disturbance 3/31/2008 Female 5/1/2008 Consumer United States
Primary
Concomitant
Insomnia Death 5/17/2007 77 Male 4/29/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 5/8/2008 United States
Primary
Concomitant
Joint Effusion Death 6/30/2007 84 Male 185 lb 5/23/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/20/2008 67 Male 165 lb 5/29/2008 United States
Primary
Concomitant
Visual Disturbance 3/31/2008 Female 128 lb 6/11/2008 Physician United States
Primary
Concomitant
Incontinence Hospitalization 5/1/2008 82 Female 176 lb 6/9/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 11/24/2007 76 Female 137 lb 6/17/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2008 Male 6/30/2008 Consumer United States
Primary
Concomitant
Visual Impairment 3/31/2008 Female 128 lb 7/14/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 11/13/2002 Male 7/21/2008 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/14/2007 59 Male 179 lb 7/29/2008 Consumer United States
Primary
Concomitant
Blue Toe Syndrome 2/2/2008 75 Male 7/29/2008 Consumer United States
Primary
Concomitant
Visual Impairment 3/31/2008 Female 128 lb 8/1/2008 Physician United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization Female 179 lb 1/9/2009 Consumer United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 1/16/2009 Lawyer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2005 Male 280 lb 1/16/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 114 lb 1/19/2009 Other Health Professional United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 1/20/2009 Consumer
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Hospitalization 12/24/2008 Female 179 lb 1/21/2009 Physician United States
Primary
Concomitant
Medication Error Other Serious Female 114 lb 2/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 2/19/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/1/2008 Female 158 lb 2/23/2009 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/19/2009 67 Male 4/1/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Death 81 Female 7/14/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 10/25/2007 73 Female 229 lb 7/17/2009 United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 7/29/2009 Physician
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 168 lb 7/22/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 80 Female 8/13/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/13/2009 Lawyer United States
Primary
Concomitant
Speech Disorder Hospitalization 50 Male 8/14/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 8/22/2009 United States
Primary
Concomitant
Convulsion Other Serious 3/19/2009 67 Male 8/24/2009 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 70 Male 8/20/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 3/17/2009 67 Male 9/15/2009 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/6/2000 51 Male 175 lb 10/5/2009 United States
Primary
Concomitant
Overdose Death 10/20/2009 83 Male 10/27/2009 Physician Italy
Primary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 11/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Death 10/20/2009 83 Male 11/26/2009 Physician Italy
Primary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/29/2009 67 Male 174 lb 1/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Abnormal Hospitalization 10/29/2009 67 Male 174 lb 3/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tenodesis Hospitalization 64 Female 3/5/2010 Lawyer United States
Primary
Concomitant
Respiratory Failure Required Intervention 2/25/2010 79 Male 222 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomyopathy Death 11/1/2009 78 Male 258 lb 4/9/2010 United States
Primary
Concomitant
Headache 2/13/2010 67 Female 4/12/2010 Other Health Professional United States
Primary
Concomitant
Venous Haemorrhage Female 4/12/2010 Consumer United States
Primary
Concomitant
Malaise 80 Male 180 lb 4/21/2010 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/3/2010 55 Female 4/23/2010 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/12/2010 92 Female 123 lb 3/16/2010 Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 3/17/2009 67 Male 7/2/2010 Consumer United States
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 93 Female 9/9/2010 United States
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Other Serious 6/15/2010 72 Female 190 lb 10/27/2010 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased 76 Male 10/13/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 48 Male 10/13/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 74 Female 200 lb 10/25/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2010 Female 11/15/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Myalgia 10/1/2009 79 Male 172 lb 12/14/2010 Consumer United States
Primary
Concomitant
Myalgia 82 Male 12/14/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Viral Other Serious 8/1/2008 76 Male 189 lb 12/20/2010 Physician United States
Primary
Concomitant
Psoriasis Other Serious 10/1/2009 58 Female 12/22/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 10/1/2009 58 Female 12/27/2010 Consumer United States
Primary
Secondary
Concomitant
Psoriasis Other Serious 10/1/2009 58 Female 1/25/2011 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 1/1/2004 61 Female 251 lb 1/28/2011 Physician United States
Primary
Concomitant
Psoriasis Hospitalization 10/1/2009 58 Female 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 1/14/2011 70 Female 2/1/2011 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 2/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Life Threatening 1/1/2008 79 Male 2/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 12/6/2010 70 Female 160 lb 12/18/2010 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/15/2009 68 Male 168 lb 2/25/2011 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Pain 12/3/2010 67 Female 3/8/2011 Consumer United States
Primary
Concomitant
Injury Death 5/11/2008 58 Female 193 lb 3/8/2011 Lawyer United States
Primary
Concomitant
Emotional Distress Other Serious 5/11/2008 58 Female 193 lb 3/8/2011 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization 11/30/2010 74 Male 127 lb 3/17/2011 Consumer United States
Primary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Erythema Disability 5/11/2006 69 Male 202 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Deformity Other Serious 7/1/2005 74 Male 148 lb 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 6/28/2005 69 Female 198 lb 4/18/2011 Other Health Professional United States
Primary
Concomitant
Diarrhoea Hospitalization 11/30/2010 74 Male 127 lb 4/19/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Death Female 141 lb 4/19/2011 Physician United States
Primary
Concomitant
Cardiac Disorder Hospitalization 4/1/2006 48 Male 239 lb 4/21/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2010 67 Female 5/9/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Other Serious 1/10/2006 78 Male 182 lb 5/9/2011 Lawyer United States
Primary
Concomitant
Pruritus Other Serious 7/1/2005 74 Male 148 lb 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Other Serious 3/17/2011 91 Male 5/18/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 5/5/2011 60 Male 190 lb 5/19/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 64 Male 216 lb 5/24/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 3/30/2011 78 Female 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Abdominal Mass Hospitalization 1/2/2011 78 Female 6/2/2011 Pharmacist Canada
Primary
Concomitant
Dilatation Ventricular Other Serious 5/20/2003 56 Male 6/17/2011 Consumer Venezuela
Primary
Concomitant
Aortic Dilatation Hospitalization 88 Female 6/20/2011 United States
Primary
Concomitant
Skin Discolouration Hospitalization 1/1/2005 57 Male 7/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 12/1/2006 79 Male 187 lb 7/14/2011 Lawyer United States
Primary
Concomitant
Death Other Serious 9/8/2006 63 Female 166 lb 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Rash Papular Other Serious 1/1/2005 72 Female 172 lb 7/16/2011 Other Health Professional United States
Primary
Concomitant
Burning Sensation Other Serious 1/1/2004 62 Female 251 lb 7/22/2011 Consumer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain 94 Male 7/25/2011 Consumer United States
Primary
Concomitant
Chest Discomfort 80 Male 7/25/2011 Consumer United States
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 3/30/2011 78 Female 7/25/2011 Consumer United States
Primary
Secondary
Concomitant
Dysstasia Death 10/1/2002 76 Female 188 lb 8/1/2011 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2007 69 Female 147 lb 8/2/2011 Lawyer United States
Primary
Concomitant
Paraesthesia 12/1/2007 80 Male 211 lb 8/5/2011 Consumer United States
Primary
Concomitant
Nervousness Other Serious Female 208 lb 8/10/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious Female 208 lb 8/15/2011 Other Health Professional United States
Primary
Concomitant

Drug Data