Coumadin combined with Enalapril Maleate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oral Intake Reduced Other Serious 1/1/2006 78 Male 168 lb 2/22/2006 United States
Primary
Concomitant
Drug Ineffective Other Serious 2/14/2006 47 Male 150 lb 2/22/2006 United States
Primary
Concomitant
Pulmonary Vascular Disorder Other Serious 5/6/2005 40 Male 140 lb 3/9/2006 United States
Primary
Concomitant
Renal Failure Other Serious 10/31/2002 63 Male 161 lb 3/20/2006 Lawyer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 3/27/2006 Physician United States
Primary
Concomitant
Sinus Arrhythmia Other Serious 5/14/2001 82 Male 172 lb 3/28/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/17/2003 71 Male 220 lb 3/28/2006 Physician United States
Primary
Concomitant
Sudden Death Death 5/1/2005 88 Male 3/14/2006 Physician United States
Primary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/31/2002 63 Male 161 lb 4/4/2006 Physician United States
Primary
Concomitant
Overdose Life Threatening 4/16/2005 81 Female 4/6/2006 Consumer United States
Primary
Concomitant
Sudden Death Other Serious 2/1/2006 67 Male 3/27/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Heart Rate Decreased Required Intervention 1/1/2000 83 Male 4/11/2006 United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/14/2001 82 Male 172 lb 4/24/2006 Physician United States
Primary
Concomitant
Post Procedural Complication Other Serious 9/1/2004 56 Male 245 lb 4/24/2006 United States
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 4/24/2006 Other Health Professional Italy
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2004 Female 5/9/2006 Other Health Professional Hungary
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 3/13/2006 83 Male 5/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/14/2001 82 Male 172 lb 5/18/2006 Physician United States
Primary
Concomitant
Rash Hospitalization 5/15/2006 64 Male 284 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Haematemesis Hospitalization 6/14/2006 72 Male 123 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Gingival Bleeding 81 Male 172 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 7/1/2005 84 Female 183 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 11/3/2005 82 Male 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 12 Male 8/1/2006 Consumer United States
Primary
Concomitant
Pain 3/1/2006 76 Male 212 lb 8/1/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 1/1/2005 Male 8/9/2006 Other Health Professional United States
Primary
Concomitant
Dizziness Male 408 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/1/2006 73 Female 9/18/2006 Consumer United States
Primary
Concomitant
Chromaturia 5/10/2006 85 Male 8/14/2006 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2002 73 Female 10/11/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/23/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Alopecia 6/1/2005 78 Female 11/13/2006 Consumer United States
Primary
Concomitant
Chills Other Serious 8/22/2006 61 Male 262 lb 11/30/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Erythema Hospitalization 7/1/2006 51 Female 11/21/2006 Consumer United States
Primary
Concomitant
Thrombosis Death 5/4/2005 Female 155 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 11/1/2006 Male 12/14/2006 Physician United States
Primary
Concomitant
Hypoxia Hospitalization 7/23/2006 81 9/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Required Intervention 10/30/2006 61 Male 162 lb 11/15/2006 Pharmacist United States
Primary
Concomitant
Blood Pressure Systolic Increased 5/16/2006 78 Male 12/28/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 12/6/2006 Male 30 lb 1/2/2007 Consumer United States
Primary
Concomitant
Heart Rate Increased Other Serious 12/29/2006 Male 170 lb 1/8/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 9/15/2006 78 Female 186 lb 9/20/2006 United States
Primary
Concomitant
Pleural Disorder Hospitalization 12/1/2006 72 Female 1/19/2007 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Death 10/1/2003 62 Male 200 lb 10/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/6/2006 Male 145 lb 2/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Other Serious Male 1/30/2007 Consumer United States
Primary
Concomitant
Rhinorrhoea Other Serious 79 Female 190 lb 8/19/2005 United States
Primary
Concomitant
Drug Ineffective Other Serious Male 170 lb 2/16/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/2/2006 60 Male 3/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Middle Insomnia 9/25/2006 20 Female 111 lb 11/6/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/1/2005 75 Male 227 lb 3/23/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 9/1/2005 75 Male 227 lb 5/29/2007 Physician United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 5/31/2006 67 Male 1/18/2007 Physician United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2005 82 Male 6/19/2007 Consumer United States
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2006 Female 163 lb 7/13/2007 Consumer United States
Primary
Concomitant
Tachycardia Life Threatening 6/24/2007 69 Female 163 lb 7/20/2007 Physician United States
Primary
Concomitant
Paranoia Hospitalization 5/9/2006 92 Male 7/24/2007 Pharmacist United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/17/2006 Female 8/8/2007 Physician United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 12/17/2006 Female 8/15/2007 Physician United States
Primary
Concomitant
Back Pain 67 Male 163 lb 9/20/2007 Consumer United States
Primary
Concomitant
Pancreatic Disorder Life Threatening 83 Male 216 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/6/2003 Female 167 lb 10/16/2007 Lawyer United States
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 1/1/2007 67 Male 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Psoriasis Other Serious 7/7/2007 81 Male 179 lb 10/31/2007 Physician United States
Primary
Concomitant
Drug Ineffective 57 Male 11/13/2007 Consumer United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 9/18/2007 57 Male 11/9/2007 United States
Primary
Concomitant
Vision Blurred 1/8/2007 60 Male 11/14/2007 Consumer United States
Primary
Concomitant
Alopecia 81 Female 11/14/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2005 72 Male 11/14/2007 Consumer United States
Primary
Concomitant
Fatigue 7/1/2007 61 Male 11/14/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/30/2007 66 Male 194 lb 11/19/2007 Consumer United States
Primary
Secondary
Concomitant
Disease Recurrence Other Serious 9/9/2007 77 Male 162 lb 11/6/2007 United States
Primary
Concomitant
Heart Rate Increased 12/19/2007 Male 1/29/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Required Intervention 10/1/2007 77 Female 12/18/2007 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/5/2007 Female 212 lb 6/27/2007 Pharmacist United States
Primary
Concomitant
Heart Rate Increased Other Serious 9/1/2007 Female 1/15/2008 Physician United States
Primary
Concomitant
Shock Hypoglycaemic Hospitalization 7/1/2006 76 Female 229 lb 3/18/2008 Other Health Professional United States
Primary
Concomitant
Platelet Count Increased Hospitalization 3/19/2008 Male 143 lb 3/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/13/2008 Female 224 lb 4/8/2008 Consumer United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 2/1/2004 70 Female 4/21/2008 Consumer Italy
Primary
Secondary
Concomitant
Syncope Other Serious 12/1/2007 79 Male 4/21/2008 Physician United States
Primary
Concomitant
Pruritus 10/29/2007 Male 190 lb 4/29/2008 United States
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Hospitalization 5/9/2008 83 Male 5/28/2008 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 2/1/2008 Male 6/10/2008 Other Health Professional United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2008 Female 197 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Infection Hospitalization Female 58 lb 6/18/2008 Consumer United States
Primary
Concomitant
Incontinence Hospitalization 5/1/2008 82 Female 176 lb 6/9/2008 United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2008 79 Female 196 lb 7/10/2008 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2008 79 Female 196 lb 7/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/7/2008 85 Male 7/31/2008 Physician Italy
Primary
Secondary
Concomitant
International Normalised Ratio Fluctuation Other Serious 62 Male 181 lb 7/29/2008 Consumer United States
Primary
Concomitant
Diarrhoea 5/1/2007 72 Female 159 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 6/1/2007 Male 130 lb 7/29/2008 Consumer United States
Primary
Concomitant
Burning Sensation 1/1/2008 58 Male 231 lb 7/29/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/17/2003 Male 8/5/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/7/2008 75 Male 8/6/2008 Physician Italy
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2008 79 Female 196 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/7/2008 85 Male 9/9/2008 Physician Italy
Primary
Secondary
Concomitant
Swelling Death 4/1/2006 Female 135 lb 9/15/2008 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 3/27/2008 79 Female 164 lb 9/22/2008 United States
Primary
Concomitant
Skin Ulcer Hospitalization 7/8/2008 73 Male 232 lb 10/8/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 9/19/2008 67 Female 10/27/2008 Physician Italy
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 9/1/2008 Female 10/28/2008 Consumer United States
Primary
Concomitant
Syncope Hospitalization 9/19/2008 67 Female 10/31/2008 Physician Italy
Primary
Secondary
Concomitant
Thrombosis Hospitalization 69 Female 11/21/2008 Consumer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 9/1/2008 Female 12/1/2008 Physician United States
Primary
Concomitant
Visual Impairment Other Serious Male 240 lb 6/18/2008 Consumer United States
Primary
Concomitant
Liver Tenderness 11/1/2007 86 Male 12/17/2008 Consumer United States
Primary
Concomitant
Wound Secretion Hospitalization 9/1/2008 Female 12/23/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 50 Male 12/29/2008 Lawyer United States
Primary
Concomitant
Vaginal Haemorrhage 10/27/2008 83 Female 12/15/2008 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 82 Female 172 lb 1/8/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 50 Male 12/29/2008 United States
Primary
Concomitant
Rash 1/1/2008 24 Female 104 lb 1/15/2009 Physician United States
Primary
Concomitant
Wheelchair User Hospitalization 7/8/2008 73 Male 232 lb 1/21/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/1/2007 58 Male 3/3/2009 Lawyer Puerto Rico
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/1/2007 58 Male 3/16/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Hospitalization Female 160 lb 4/23/2009 Consumer United States
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization Female 160 lb 5/1/2009 Physician United States
Primary
Concomitant
Parkinson's Disease Other Serious 1/1/1997 Male 5/5/2009 Consumer United States
Primary
Concomitant
Vertigo Other Serious 66 Female 5/13/2009 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 5/30/2009 Physician United States
Primary
Concomitant
Dyspnoea Life Threatening 10/23/2008 73 Female 6/25/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Vertigo Hospitalization 66 Female 7/1/2009 Lawyer United States
Primary
Concomitant
Skin Tightness Other Serious 10/1/2006 71 Female 128 lb 7/14/2009 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 62 Female 7/12/2009 United States
Primary
Concomitant
Skin Tightness Other Serious 10/1/2006 71 Female 128 lb 7/16/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization Female 130 lb 7/16/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/16/2009 Male 7/18/2009 Pharmacist
Primary
Concomitant
International Normalised Ratio Decreased 5/22/2009 81 Male 205 lb 7/22/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 62 Female 7/19/2009 Lawyer United States
Primary
Concomitant
Skin Tightness Other Serious 10/1/2006 71 Female 128 lb 7/29/2009 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 5/22/2009 81 Male 205 lb 7/22/2009 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization Female 130 lb 8/4/2009 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 Female 8/3/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 4/16/2009 Male 8/6/2009 Pharmacist
Primary
Concomitant
Weight Decreased Hospitalization 62 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Cardiac Arrest Hospitalization 7/21/2009 Male 178 lb 8/6/2009 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 80 Male 7/31/2009 United States
Primary
Concomitant
Vomiting Hospitalization 8/17/2001 76 Female 157 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 49 Male 8/5/2009 United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 49 Male 8/14/2009 United States
Primary
Concomitant
International Normalised Ratio Abnormal Other Serious 6/11/2009 Male 8/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 79 Male 8/18/2009 United States
Primary
Concomitant
Pruritus 6/27/2009 Female 8/22/2009 United States
Primary
Concomitant
Pruritus Male 8/23/2009 United States
Primary
Concomitant

Drug Data