Corticosteroids combined with Danazol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Acute Myeloid Leukaemia Death 11/6/2008 Female 2/26/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 1/29/2009 Female 4/2/2009 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 4/16/2009 Male 5/1/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 5/15/2009 Physician United States
Primary
Concomitant
Haematological Malignancy Death 4/16/2009 Male 5/19/2009 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Death 4/16/2009 Male 5/20/2009 Physician United States
Primary
Concomitant
Pneumonia Death 4/7/2009 56 Male 6/2/2009 Physician United States
Primary
Concomitant
Disease Progression Death 4/16/2009 Male 182 lb 6/19/2009 Physician United States
Primary
Concomitant
Death Death 10/11/2008 Female 9/10/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 165 lb 10/7/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 165 lb 11/24/2009 Physician United States
Primary
Concomitant
Renal Haematoma Hospitalization 12/30/2009 43 Female 1/25/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 1/27/2010 Physician United States
Primary
Concomitant
Liver Disorder Other Serious Female 2/4/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 2/27/2009 Male 162 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2009 Male 2/12/2010 Physician United States
Primary
Concomitant
Liver Disorder Female 2/15/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Death Female 2/16/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Death Female 3/2/2010 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 12/30/2009 43 Female 3/9/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Death 10/14/2009 82 Female 3/10/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2009 Female 133 lb 3/17/2010 Physician United States
Primary
Concomitant
Death Death Male 3/19/2010 Physician United States
Primary
Concomitant
Weight Decreased Death 82 Female 4/1/2010 Other Health Professional United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 2/16/2009 67 Male 196 lb 4/1/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 4/1/2010 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 2/16/2009 67 Male 196 lb 4/15/2010 Physician United States
Primary
Concomitant
Death Death Male 4/21/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 9/10/2009 67 Female 4/22/2010 Physician United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious Female 4/23/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/22/2009 87 Female 4/29/2010 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 12/27/2009 43 Female 5/4/2010 Other Health Professional United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 2/12/2010 48 Female 164 lb 5/5/2010 Physician United States
Primary
Concomitant
Procedural Pain Other Serious 9/5/2009 67 Female 5/5/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/22/2009 87 Female 5/6/2010 Physician United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 2/12/2010 48 Female 164 lb 5/7/2010 Physician United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 2/12/2010 48 Female 164 lb 5/13/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/17/2009 87 Female 163 lb 5/19/2010 Physician United States
Primary
Concomitant
Hypertension Other Serious 3/1/2009 83 Male 205 lb 5/21/2010 Physician United States
Primary
Concomitant
Death Death Female 5/21/2010 Physician United States
Primary
Concomitant
Economic Problem Other Serious Male 5/25/2010 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Male 5/27/2010 Physician United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 66 Male 6/1/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2009 87 Female 163 lb 6/8/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Death 1/1/2010 58 Male 190 lb 6/30/2010 Physician United States
Primary
Concomitant
Death Death Male 7/9/2010 Physician United States
Primary
Concomitant
Death Death Female 7/12/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 12/1/2008 67 Male 7/13/2010 Physician United States
Primary
Concomitant
Death Death Male 7/14/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 7/20/2010 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death Male 172 lb 7/21/2010 Physician United States
Primary
Concomitant
Death Death Female 7/27/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Death 1/23/2010 72 Female 143 lb 8/4/2010 Consumer Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious Female 8/4/2010 Physician United States
Primary
Concomitant
Cardiac Arrest Death Male 8/11/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 6/29/2010 69 Female 8/17/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2009 87 Female 163 lb 8/18/2010 Physician United States
Primary
Concomitant
Hepatic Failure Death 89 Female 8/23/2010 Physician United States
Primary
Concomitant
Economic Problem Other Serious 1/1/2009 77 Male 8/26/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2009 64 Male 8/26/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 8/27/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 12/1/2008 60 Male 156 lb 8/30/2010 Physician United States
Primary
Concomitant
Splenectomy Other Serious 1/1/2009 35 Male 8/31/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 89 Female 9/1/2010 Physician United States
Primary
Concomitant
Surgery Hospitalization 6/29/2010 69 Female 9/7/2010 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 1/5/2009 79 Male 9/14/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Death 1/1/2010 58 Male 190 lb 9/17/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 63 Male 9/21/2010 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 10/6/2009 58 Female 9/30/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 63 Male 9/30/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 10/4/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 10/8/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 63 Male 10/8/2010 Physician United States
Primary
Concomitant
Splenectomy Other Serious 1/1/2010 14 Female 10/13/2010 Physician United States
Primary
Concomitant
Surgery Hospitalization 6/29/2010 69 Female 10/14/2010 Physician United States
Primary
Concomitant
Thrombotic Stroke Hospitalization 8/24/2010 59 Female 10/19/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/25/2010 Other Health Professional United States
Primary
Concomitant
Cerebral Haemorrhage Death 11/2/2010 Physician United States
Primary
Concomitant
Liver Disorder Other Serious Male 11/5/2010 Other Health Professional Puerto Rico
Primary
Concomitant
Colon Cancer Other Serious 11/5/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 5/3/2010 11/12/2010 Other Health Professional United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/3/2010 11/12/2010 Other Health Professional United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/3/2010 11/15/2010 Other Health Professional United States
Primary
Concomitant
Surgery Hospitalization 6/29/2010 69 Female 11/19/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/6/2010 11/22/2010 Other Health Professional United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/3/2010 11/23/2010 Other Health Professional United States
Primary
Concomitant
Splenomegaly Other Serious 5/18/2010 63 Male 12/10/2010 Other Health Professional Puerto Rico
Primary
Concomitant
Death Death 10/24/2010 12/16/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2010 12/21/2010 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/1/2010 12/22/2010 Physician United States
Primary
Concomitant
Death Death 1/1/2010 12/23/2010 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/1/2010 12/25/2010 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 12/30/2010 Physician United States
Primary
Concomitant
Evans Syndrome Other Serious 1/1/2010 12/30/2010 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 1/7/2011 Physician United States
Primary
Concomitant
Angioedema Other Serious 1/1/2010 1/10/2011 Physician United States
Primary
Concomitant
Localised Oedema Other Serious 1/1/2010 1/11/2011 Other Health Professional United States
Primary
Concomitant
Evans Syndrome Other Serious 1/1/2010 1/13/2011 Physician United States
Primary
Concomitant
Angioedema Other Serious 1/1/2010 1/17/2011 Physician United States
Primary
Concomitant
Bone Marrow Disorder Disability 10/29/2009 81 Male 1/25/2011 Physician United States
Primary
Concomitant
Bone Marrow Disorder Disability 10/29/2009 81 Male 1/27/2011 Physician United States
Primary
Concomitant
Hyperhidrosis Other Serious 10/29/2009 81 Male 1/31/2011 Other Health Professional United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 67 Female 2/11/2011 Physician United States
Primary
Concomitant
Chronic Myelomonocytic Leukaemia Other Serious 5/18/2010 63 Male 2/14/2011 Consumer Puerto Rico
Primary
Concomitant
Hospitalisation Other Serious 12/17/2010 52 Female 2/15/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 67 Female 2/15/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 67 Female 2/17/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 67 Female 2/23/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 67 Female 2/23/2011 Physician United States
Primary
Concomitant
Hospitalisation Hospitalization 12/17/2010 52 Female 3/4/2011 Physician United States
Primary
Concomitant
Death Death 4/21/2010 67 Female 3/4/2011 Physician United States
Primary
Concomitant
Splenomegaly Other Serious Female 3/8/2011 Physician United States
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 1/1/2010 67 Female 3/9/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 67 Female 3/11/2011 Physician United States
Primary
Concomitant
Colon Cancer Hospitalization Male 3/11/2011 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious Female 3/16/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization Male 3/21/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization Male 3/21/2011 Physician United States
Primary
Concomitant
Hospitalisation Other Serious 12/17/2010 52 Female 3/22/2011 Other Health Professional United States
Primary
Concomitant
Hepatic Lesion Hospitalization Male 3/23/2011 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 12/17/2010 52 Female 3/23/2011 Other Health Professional United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/12/2011 67 Female 3/24/2011 Physician United States
Primary
Concomitant
Splenomegaly Other Serious Female 3/24/2011 Physician United States
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 1/12/2011 67 Female 3/28/2011 Physician United States
Primary
Concomitant
Aneurysm Other Serious 1/1/2011 61 Male 3/29/2011 Physician United States
Primary
Concomitant
Aneurysm Other Serious 1/1/2011 61 Male 3/30/2011 Physician United States
Primary
Concomitant
Death Death 4/22/2010 67 Female 3/31/2011 Physician United States
Primary
Concomitant
Aneurysm Other Serious 1/1/2011 61 Male 4/4/2011 Physician United States
Primary
Concomitant
Hyperhidrosis Other Serious 10/29/2009 81 Male 4/6/2011 Physician United States
Primary
Concomitant
Panniculitis Hospitalization 2/17/2011 68 Male 4/8/2011 Physician United States
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 12/16/2010 52 Female 4/11/2011 Other Health Professional United States
Primary
Concomitant
Aneurysm Other Serious 1/1/2011 61 Male 4/11/2011 Physician United States
Primary
Concomitant
Splenomegaly Other Serious Female 4/18/2011 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 2/17/2011 68 Male 4/19/2011 Physician United States
Primary
Concomitant
Chest Pain Disability 10/29/2009 81 Male 4/26/2011 Physician United States
Primary
Concomitant
Pyrexia Disability 10/29/2009 81 Male 5/2/2011 Other Health Professional United States
Primary
Concomitant
Splenomegaly Other Serious 1/24/2011 42 Female 5/13/2011 Physician United States
Primary
Concomitant
Musculoskeletal Pain Other Serious 1/24/2011 42 Female 5/25/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 5/25/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 5/25/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 5/25/2011 Physician United States
Primary
Concomitant
Piriformis Syndrome Other Serious 1/24/2011 42 Female 6/1/2011 Physician United States
Primary
Concomitant
Bone Marrow Disorder Hospitalization 10/29/2009 81 Male 6/3/2011 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 50 Male 7/20/2011 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 11/1/2010 57 Female 7/25/2011 Physician United States
Primary
Concomitant
Death Death 7/19/2011 61 Male 8/3/2011 Pharmacist United States
Primary
Concomitant
Haematological Malignancy Death 1/1/2010 82 Female 8/3/2011 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis Death 10/29/2009 81 Male 8/3/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 50 Male 8/10/2011 Physician United States
Primary
Concomitant
Haemorrhagic Stroke Life Threatening 3/5/2011 51 Female 8/12/2011 Consumer United States
Primary
Concomitant

Drug Data