Cordarone combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Loss Of Consciousness Other Serious 1/2/2006 75 Male 190 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Bradycardia Hospitalization Female 168 lb 1/27/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 4/1/2002 65 Male 190 lb 2/17/2006 Physician United States
Primary
Concomitant
Optic Neuritis Other Serious 1/1/2004 72 Male 160 lb 1/17/2006 Physician United States
Primary
Concomitant
Hyperthyroidism Other Serious 8/1/2005 60 Male 140 lb 1/17/2006 Physician United States
Primary
Concomitant
Blindness Other Serious 1/1/2000 62 Male 190 lb 1/17/2006 United States
Primary
Concomitant
Vestibular Disorder Other Serious 1/1/2004 85 Male 1/17/2006 Physician United States
Primary
Concomitant
Vision Blurred Disability 2/1/2004 85 Male 192 lb 1/17/2006 Physician United States
Primary
Concomitant
Hepatic Failure Other Serious 6/20/2005 87 Male 180 lb 1/17/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 1/22/2006 58 Female 3/1/2006 Other Health Professional France
Primary
Concomitant
Interacting
Wallenberg Syndrome Hospitalization 1/1/2002 65 Female 146 lb 3/7/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Required Intervention 9/18/2003 65 Female 155 lb 3/3/2006 Physician United States
Primary
Concomitant
Swelling Other Serious 1/1/2004 62 Female 143 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Polymyalgia Rheumatica Other Serious 3/1/2006 91 Male 126 lb 3/28/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/1/2006 93 Female 3/29/2006 Physician United States
Primary
Concomitant
Epistaxis Hospitalization 2/6/2006 73 Male 4/13/2006 Other Health Professional France
Primary
Concomitant
Interacting
Intracranial Pressure Increased Hospitalization 2/1/2006 79 Female 4/14/2006 Other Health Professional France
Primary
Concomitant
Ventricular Tachycardia Hospitalization 4/1/2002 65 Male 190 lb 4/20/2006 Physician United States
Primary
Concomitant
Prothrombin Time Ratio Decreased Hospitalization 2/12/2006 95 Male 4/21/2006 Other Health Professional France
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/27/2002 65 Male 198 lb 4/26/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/6/2006 73 Male 4/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/17/2006 12 Female 53 lb 5/9/2006 Consumer France
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Life Threatening 5/7/2006 58 Male 134 lb 5/9/2006 Pharmacist United States
Primary
Secondary
Concomitant
Prothrombin Time Shortened Other Serious 3/12/2006 12 Female 53 lb 5/12/2006 Other Health Professional France
Primary
Concomitant
Interacting
Prothrombin Level Decreased Hospitalization 3/17/2006 12 Female 53 lb 5/2/2006 Physician France
Primary
Secondary
Concomitant
Periorbital Disorder Hospitalization 4/4/2006 84 Female 5/23/2006 France
Primary
Secondary
Concomitant
Renal Failure 3/8/2005 64 Male 4/4/2006 Physician United States
Primary
Concomitant
Middle Insomnia Other Serious 1/1/2006 Female 6/14/2006 United States
Primary
Secondary
Concomitant
Fall Hospitalization 4/4/2006 84 Female 6/29/2006 France
Primary
Secondary
Concomitant
Fatigue Hospitalization 5/31/2006 67 Male 169 lb 7/6/2006 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 79 Female 7/14/2006 Physician France
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2006 47 Male 141 lb 7/31/2006 Physician France
Primary
Interacting
Speech Disorder Hospitalization 4/4/2006 84 Female 7/24/2006 France
Primary
Secondary
Concomitant
Erythema 1/1/2005 73 Female 154 lb 8/1/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Male 163 lb 8/4/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 6/1/2000 51 Female 8/10/2006 Lawyer United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 6/1/2006 64 Male 8/4/2006 Physician United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 6/28/2006 64 Male 8/14/2006 Physician United States
Primary
Concomitant
Metabolic Acidosis Death 2/9/2006 58 Female 8/11/2006 France
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 7/3/2006 76 Male 10/3/2006 France
Primary
Concomitant
Neutropenia Life Threatening 3/18/2006 77 Female 10/27/2006 Italy
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/17/2006 83 Female 11/6/2006 Other Health Professional Italy
Primary
Concomitant
Hyperpyrexia Other Serious 7/24/2006 49 Male 146 lb 11/6/2006 Physician Italy
Primary
Concomitant
Pneumonia Hospitalization 11/7/2006 Female 163 lb 11/21/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 5/31/2003 79 Female 11/10/2006 France
Primary
Secondary
Concomitant
Syncope Hospitalization 10/4/2005 79 Female 11/16/2006 Italy
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 8/26/2006 76 Female 11/16/2006 France
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/7/2006 Female 163 lb 11/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Blood Pressure Fluctuation Other Serious 8/15/2006 72 Male 12/1/2006 Consumer Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 5/31/2003 79 Female 12/5/2006 Other Health Professional United States
Primary
Concomitant
Interacting
Oedema Peripheral Other Serious 7/24/2006 49 Male 146 lb 12/7/2006 Physician Italy
Primary
Concomitant
Sepsis Hospitalization 11/7/2006 Female 163 lb 12/19/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Extrasystoles Life Threatening 5/31/2003 79 Female 12/5/2006 France
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/2/2006 75 Male 9/12/2006 United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/7/2006 78 Male 1/10/2007 Physician France
Primary
Secondary
Concomitant
Skin Lesion Other Serious 11/7/2006 78 Male 1/11/2007 France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/7/2006 78 Male 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 9/28/2006 70 Male 1/25/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rash Other Serious 12/12/2006 62 Male 1/24/2007 Italy
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/1/2004 84 Female 2/5/2007 Other Health Professional France
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 10/5/2006 78 Male 2/15/2007 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/1/2004 84 Female 2/21/2007 Other Health Professional France
Primary
Concomitant
Interacting
Blood Pressure Decreased Other Serious 8/15/2006 72 Male 2/28/2007 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Male 2/26/2007 Consumer Canada
Primary
Concomitant
Pulmonary Toxicity Hospitalization 9/1/2006 81 Male 1/11/2007 United States
Primary
Concomitant
Dyspnoea Exertional Other Serious 1/1/2005 75 Female 187 lb 1/11/2007 Pharmacist United States
Primary
Concomitant
Renal Disorder Other Serious 1/1/2006 81 Female 122 lb 4/23/2007 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 4/1/2007 83 Female 7/2/2007 Other Health Professional France
Primary
Concomitant
Interacting
Tachycardia Hospitalization 5/1/2007 Male 178 lb 7/2/2007 Consumer United States
Primary
Concomitant
Pneumonia Primary Atypical Hospitalization 6/1/2007 81 Male 172 lb 7/17/2007 Other Health Professional United States
Primary
Concomitant
Medication Error 6/13/2007 57 Male 8/8/2007 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 Female 150 lb 9/10/2007 Physician United States
Primary
Concomitant
Ocular Hyperaemia Disability 11/1/2005 85 Male 142 lb 8/31/2007 Other Health Professional United States
Primary
Concomitant
Ocular Hyperaemia Disability 11/1/2005 85 Male 153 lb 9/27/2007 Other Health Professional United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 2/23/2007 86 Female 10/18/2007 Other Health Professional France
Primary
Secondary
Pharmaceutical Product Complaint 11/1/2006 71 Male 10/25/2007 Consumer United States
Primary
Concomitant
Uterine Neoplasm Hospitalization 3/6/2007 Female 10/26/2007 Other Health Professional France
Primary
Secondary
Neoplasm Progression Hospitalization 3/6/2007 86 Female 10/26/2007
Primary
Secondary
Osteoporosis Other Serious 1/1/2002 Female 10/29/2007 Consumer United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 9/27/2007 85 Male 11/27/2007 Other Health Professional France
Primary
Concomitant
Weight Decreased Hospitalization 10/22/1999 51 Female 11/14/2007 United States
Primary
Secondary
Concomitant
Faeces Discoloured 1/1/2007 63 Male 172 lb 12/17/2007 United States
Primary
Concomitant
Hepatic Cirrhosis Life Threatening 6/1/2007 88 Female 12/20/2007 Other Health Professional France
Primary
Concomitant
Tremor Hospitalization 10/14/2007 Female 12/21/2007 Physician France
Primary
Concomitant
Parkinsonism Hospitalization 10/14/2007 97 Female 12/21/2007 France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2004 Female 150 lb 1/2/2008 Physician United States
Primary
Concomitant
Tremor Hospitalization 10/14/2007 Female 1/3/2008 Physician France
Primary
Concomitant
Parkinsonism Hospitalization 10/14/2007 97 Female 12/28/2007 France
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 7/10/2007 82 Female 1/18/2008 Consumer France
Primary
Concomitant
Renal Failure Hospitalization 1/3/2008 78 Female 1/28/2008 Pharmacist Italy
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/3/2008 Female 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/4/2007 83 Female 2/4/2008 Consumer France
Primary
Secondary
Concomitant
Optic Ischaemic Neuropathy Other Serious 12/1/2003 60 1/24/2008 United States
Primary
Concomitant
Blindness Other Serious 1/1/2006 65 Male 1/24/2008 United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2004 64 Female 138 lb 1/24/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 1/3/2008 Female 2/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 3/4/2008 Male 3/24/2008 Other Health Professional France
Primary
Concomitant
Thrombosis Death 2/22/2008 85 Female 3/27/2008 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/12/2007 79 Male 4/3/2008 Other Health Professional France
Primary
Concomitant
Gait Disturbance Other Serious 3/4/2008 Male 4/28/2008 Other Health Professional France
Primary
Concomitant
Weight Decreased 82 Female 4/23/2008 Consumer United States
Primary
Concomitant
Autoimmune Thrombocytopenia Hospitalization 2/25/2008 Female 164 lb 5/1/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 84 Female 5/30/2008 Pharmacist Canada
Primary
Concomitant
Tremor 9/1/2007 82 Female 160 lb 4/10/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2008 94 Female 7/10/2008 Physician France
Primary
Secondary
Haematoma Hospitalization 6/1/2008 94 Female 7/11/2008 Consumer France
Primary
Secondary
Subcutaneous Haematoma Hospitalization 6/15/2008 Female 7/15/2008 Other Health Professional France
Primary
Concomitant
Interacting
Visual Acuity Reduced Other Serious 8/17/2003 Male 8/5/2008 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Haematoma Hospitalization 6/1/2008 94 Female 9/12/2008 Consumer France
Primary
Secondary
Urinary Tract Infection Hospitalization 6/15/2008 94 Female 9/12/2008 Physician France
Primary
Secondary
Subcutaneous Haematoma Hospitalization 6/15/2008 Female 9/18/2008 Other Health Professional France
Primary
Concomitant
Interacting
Paraesthesia 81 Female 125 lb 10/7/2008 United States
Primary
Concomitant
Pain Other Serious 9/1/2008 85 Female 10/22/2008 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Required Intervention 75 Male 10/29/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 76 Female 11/4/2008 United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 1/28/2008 Female 12/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 1/28/2008 Female 12/11/2008 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 50 Male 12/29/2008 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 50 Male 12/29/2008 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 6/15/2008 Female 1/15/2009 Other Health Professional France
Primary
Concomitant
Interacting
Rectal Haemorrhage Other Serious 10/16/2008 70 Male 1/26/2009 Physician France
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/13/2008 87 Female 1/27/2009 Physician France
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/27/2008 84 Female 2/4/2009 Physician France
Primary
Concomitant
Interacting
Thrombocytopenia Hospitalization 1/12/2009 84 Female 2/5/2009 Physician France
Primary
Concomitant
Joint Injury Hospitalization 11/12/2007 86 Male 2/6/2009 Physician Italy
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 10/27/2008 84 Female 2/6/2009 Consumer France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 10/27/2008 Female 2/6/2009 Other Health Professional France
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 10/27/2008 Female 2/6/2009 Physician France
Primary
Concomitant
Interacting
Hyperthyroidism Hospitalization 6/15/2008 Female 2/6/2009 Other Health Professional France
Primary
Concomitant
Interacting
Joint Injury Hospitalization 11/12/2007 86 Male 2/26/2009 Physician Italy
Primary
Secondary
Concomitant
Pyrexia Death 71 Male 2/16/2009 France
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 11/1/2008 Male 196 lb 3/25/2009 Consumer United States
Primary
Concomitant
Pallor Hospitalization 12/18/2007 Female 4/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 8/10/2000 57 Male 344 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Pallor Hospitalization 12/18/2007 88 Female 4/6/2009 Physician France
Primary
Secondary
Concomitant
Hyperthyroidism Other Serious 6/15/2008 Female 4/7/2009 Other Health Professional France
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 1/14/2009 Female 4/8/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/23/2009 73 Male 243 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/10/2002 51 Male 290 lb 4/21/2009 United States
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 1/1/2009 Female 4/29/2009 Other Health Professional France
Primary
Concomitant
Transaminases Increased Hospitalization 3/30/2009 Male 5/5/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hernia Hospitalization 69 Male 146 lb 5/7/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Death 85 Female 5/18/2009 Lawyer United States
Primary
Concomitant
Haemoptysis Hospitalization 5/19/2009 75 Male 6/16/2009 Physician France
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 5/25/2009 71 Male 6/18/2009 Physician Italy
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 4/12/2009 74 Female 6/18/2009 Physician France
Primary
Concomitant
Haemoptysis Other Serious 5/19/2009 74 6/19/2009 Other Health Professional France
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 5/19/2009 Male 6/19/2009 Other Health Professional France
Primary
Concomitant
Interacting
Renal Failure Acute Hospitalization 5/25/2009 71 Male 6/23/2009 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/25/2009 Male 6/25/2009 Physician Italy
Primary
Secondary
Concomitant

Drug Data