Comtan combined with Pramipexole Dihydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cholelithiasis Other Serious 1/1/2005 85 Female 1/10/2006 Pharmacist Canada
Primary
Concomitant
Cholelithiasis Other Serious 1/1/2005 85 Female 1/5/2006 Canada
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2005 85 Female 140 lb 2/10/2006 Pharmacist Canada
Primary
Concomitant
Tremor Other Serious 68 Male 9/22/2006 Physician Spain
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 68 Male 9/12/2006 Spain
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/1998 58 Male 2/19/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 5/23/2007 70 6/5/2007 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 5/23/2007 70 6/15/2007 Japan
Primary
Concomitant
Shock Death 9/2/1997 62 Female 9/8/2007 Physician Japan
Primary
Secondary
Shock Death 9/2/1997 62 Female 123 lb 9/15/2007 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/21/2006 71 Female 9/18/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 8/21/2006 71 Female 9/18/2007 Physician United States
Primary
Concomitant
Shock Death 9/2/1997 62 Female 123 lb 10/12/2007 Physician Japan
Primary
Secondary
Restlessness Other Serious 8/7/2007 74 Male 10/12/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Sudden Death Death 9/2/2007 62 Female 10/17/2007 Japan
Primary
Secondary
Hepatitis Other Serious 9/20/2007 66 Male 11/6/2007 Physician Japan
Primary
Concomitant
Renal Cyst Other Serious 9/20/2007 66 Male 165 lb 11/15/2007 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 8/12/2007 65 Male 11/5/2007 Japan
Primary
Concomitant
Hepatitis Other Serious 9/20/2007 66 Male 11/13/2007 Japan
Primary
Concomitant
Renal Cyst Other Serious 9/20/2007 66 Male 165 lb 11/30/2007 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 8/12/2007 65 Male 11/15/2007 Japan
Primary
Concomitant
Renal Cyst 9/20/2007 66 Male 165 lb 12/15/2007 Physician Japan
Primary
Secondary
Concomitant
Death Death 50 Male 12/18/2007 Physician China
Primary
Concomitant
Nail Discolouration Hospitalization 9/22/2007 80 Female 12/31/2007 Physician Japan
Primary
Concomitant
Death Death 12/1/2007 50 Male 12/21/2007 China
Primary
Concomitant
Somnolence Hospitalization 11/19/2007 73 Female 12/21/2007 Japan
Primary
Secondary
Concomitant
Hyperkinesia Other Serious 9/15/2007 72 Female 12/12/2007 Japan
Primary
Concomitant
Nail Discolouration Hospitalization 10/11/2007 80 Female 1/10/2008 Japan
Primary
Concomitant
Nail Discolouration Hospitalization 9/22/2007 80 Female 1/28/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 1/16/2008 62 Female 2/5/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 1/16/2008 62 Female 2/5/2008 Physician Japan
Primary
Concomitant
Shock Death 1/16/2008 62 Female 2/19/2008 Physician Japan
Primary
Concomitant
Nail Discolouration Hospitalization 9/22/2007 80 Female 2/4/2008 Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 5/23/2007 70 2/23/2008 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2007 76 Female 2/14/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 1/16/2008 62 Female 2/7/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 1/16/2008 62 Female 3/12/2008 Physician Japan
Primary
Concomitant
Treatment Noncompliance Death 1/16/2008 62 Female 2/22/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 80 3/13/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 80 3/13/2008 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 5/23/2007 70 2/27/2008 Japan
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2007 76 Female 3/10/2008 Japan
Primary
Concomitant
Shock Other Serious 1/16/2008 62 Female 3/17/2008 Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2008 80 Female 3/17/2008 Physician Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 1/24/2008 73 Male 4/6/2008 Physician
Primary
Concomitant
Shock Other Serious 1/16/2008 62 Female 4/11/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 1/16/2008 62 Female 4/14/2008 Physician Japan
Primary
Concomitant
Vomiting 12/1/2007 70 Male 231 lb 4/4/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2007 76 Female 106 lb 4/21/2008 Japan
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 73 Male 4/9/2008 Japan
Primary
Concomitant
Weight Decreased Other Serious 7/1/2007 76 Female 106 lb 4/25/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2008 80 Female 5/1/2008 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 7/1/2007 76 Female 4/30/2008 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 1/4/2008 80 Female 5/16/2008 Japan
Primary
Concomitant
Viral Infection Other Serious 3/19/2008 65 Female 6/19/2008 Pharmacist Japan
Primary
Concomitant
Sudden Onset Of Sleep Disability 3/17/2008 Male 139 lb 6/20/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/26/2008 49 Male 6/11/2008 Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious Female 7/3/2008 Japan
Primary
Concomitant
Viral Infection Other Serious 3/19/2008 65 Female 6/25/2008 Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 10/16/2007 69 Female 7/10/2008 Japan
Primary
Concomitant
Parkinson's Disease Hospitalization 7/8/2008 Female 7/31/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/30/2008 Male 8/8/2008 Physician Japan
Primary
Concomitant
Pain In Extremity Hospitalization 6/4/2008 76 Female 99 lb 8/8/2008 Physician Japan
Primary
Concomitant
Parkinson's Disease Hospitalization 7/8/2008 Female 8/6/2008 Japan
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 8/14/2008 55 Male 8/26/2008 Physician Japan
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 8/14/2008 Male 9/10/2008 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 60 Male 9/22/2008 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 Male 9/26/2008 Physician Japan
Primary
Concomitant
Temperature Regulation Disorder Hospitalization 8/14/2008 58 Male 9/22/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 68 Male 10/9/2008 Japan
Primary
Concomitant
Mental Disorder Hospitalization Female 10/17/2008 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 6/4/2008 Female 99 lb 10/21/2008 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 9/16/2008 60 Male 10/29/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Echolalia Hospitalization Female 10/24/2008 Japan
Primary
Concomitant
Urinary Incontinence Hospitalization 5/26/2008 49 Male 10/27/2008 Japan
Primary
Concomitant
Humerus Fracture Other Serious 6/4/2008 76 Female 10/30/2008 Japan
Primary
Concomitant
Pyrexia Hospitalization 9/16/2008 60 Male 11/4/2008 Japan
Primary
Secondary
Concomitant
Therapeutic Response Increased Other Serious 7/7/2008 Female 11/12/2008 Physician Japan
Primary
Concomitant
Interacting
Hepatic Function Abnormal Other Serious Female 11/18/2008 Physician Japan
Primary
Concomitant
Palpitations Other Serious 7/7/2008 70 Female 11/24/2008 Japan
Primary
Secondary
Concomitant
Nausea Other Serious 7/5/2007 63 Male 11/27/2008 Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 10/16/2007 69 Female 12/1/2008 Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 76 Female 12/8/2008 Other Health Professional Japan
Primary
Concomitant
Nausea Other Serious 7/5/2007 63 Male 12/5/2008 Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 76 Female 12/17/2008 Japan
Primary
Concomitant
Humerus Fracture Other Serious 11/10/2008 Female 12/26/2008 Other Health Professional Japan
Primary
Concomitant
Dyskinesia Other Serious 3/1/2008 Female 99 lb 2/3/2009 Other Health Professional Japan
Primary
Concomitant
Renal Failure Other Serious 78 Female 2/5/2009 Pharmacist Japan
Primary
Concomitant
Renal Failure Other Serious 1/26/2009 78 Female 2/11/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/26/2009 78 Female 2/16/2009 Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 10/1/2008 59 Female 2/17/2009 Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 11/10/2008 76 Female 2/23/2009 Japan
Primary
Concomitant
X-ray Gastrointestinal Tract Abnormal Other Serious 12/26/2007 Female 2/26/2009 Physician Japan
Primary
Concomitant
X-ray Gastrointestinal Tract Abnormal Other Serious 12/26/2007 Female 3/2/2009 Physician Japan
Primary
Concomitant
X-ray Gastrointestinal Tract Abnormal Other Serious 12/26/2007 Female 3/3/2009 Physician Japan
Primary
Concomitant
Surgery Hospitalization 1/21/2008 Female 3/5/2009 Other Health Professional Japan
Primary
Concomitant
Fall Other Serious 8/1/2008 69 Male 3/25/2009 Pharmacist Japan
Primary
Concomitant
Shock Other Serious 1/26/2009 78 Female 3/27/2009 Pharmacist Japan
Primary
Concomitant
X-ray Gastrointestinal Tract Abnormal Other Serious 12/26/2007 Female 77 lb 3/31/2009 Physician Japan
Primary
Concomitant
Shock Other Serious 1/26/2009 78 Female 4/3/2009 Pharmacist Japan
Primary
Concomitant
Surgery Hospitalization 1/21/2008 Female 4/6/2009 Other Health Professional Japan
Primary
Concomitant
Dyskinesia Other Serious 8/1/2008 69 Male 4/30/2009 Pharmacist Japan
Primary
Concomitant
X-ray Gastrointestinal Tract Abnormal Death 12/26/2007 Female 77 lb 5/4/2009 Physician Japan
Primary
Concomitant
Surgery Hospitalization 1/21/2008 Female 5/5/2009 Other Health Professional Japan
Primary
Concomitant
X-ray Gastrointestinal Tract Abnormal Death 12/26/2007 Female 77 lb 5/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 9/11/2008 76 Female 5/15/2009 Japan
Primary
Secondary
Concomitant
X-ray Gastrointestinal Tract Abnormal Death 12/26/2007 75 Female 5/13/2009 Japan
Primary
Concomitant
Psychiatric Symptom Other Serious 8/1/2008 Male 6/23/2009 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 Male 115 lb 7/6/2009 Physician Japan
Primary
Concomitant
Eosinophilia Other Serious 6/25/2009 Male 146 lb 7/10/2009 Pharmacist Japan
Primary
Concomitant
Rash Pruritic Other Serious 70 Male 7/17/2009 Consumer Brazil
Primary
Secondary
Dysphagia Other Serious 1/1/2007 58 Male 8/7/2009 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/25/2009 Male 146 lb 8/12/2009 Pharmacist Japan
Primary
Concomitant
Salivary Hypersecretion Other Serious 1/1/2007 58 Male 8/17/2009 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 4/18/2008 59 Female 8/14/2009 Japan
Primary
Concomitant
Rash Pruritic Other Serious 70 Male 8/20/2009 Physician Brazil
Primary
Secondary
Dysphagia Other Serious 1/1/2007 58 Male 8/18/2009 Japan
Primary
Concomitant
Posture Abnormal Other Serious 1/1/2007 58 Male 8/28/2009 Physician Japan
Primary
Concomitant
Eosinophilic Cellulitis Other Serious 70 Male 8/31/2009 Physician Brazil
Primary
Secondary
Weight Decreased Hospitalization 7/1/2007 76 Female 8/31/2009 Other Health Professional Japan
Primary
Concomitant
Pain In Extremity Other Serious 6/4/2008 Female 99 lb 9/11/2009 Physician Japan
Primary
Concomitant
Salivary Hypersecretion Other Serious 1/1/2007 58 Male 9/17/2009 Other Health Professional Japan
Primary
Concomitant
Humerus Fracture Other Serious 6/4/2008 76 Female 9/21/2009 Japan
Primary
Concomitant
Pyrexia Hospitalization 4/18/2008 59 Female 9/21/2009 Japan
Primary
Concomitant
Renal Impairment Other Serious 12/18/2008 85 Female 9/25/2009 Japan
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 6/25/2009 83 Male 9/24/2009 Japan
Primary
Concomitant
Posture Abnormal Other Serious 1/1/2007 5 9/28/2009 Japan
Primary
Concomitant
Hallucination Other Serious 4/10/2009 79 Female 11/16/2009 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/18/2008 Male 75 lb 12/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 7/2/2007 Male 139 lb 3/2/2010 Other Health Professional Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 1/1/2008 60 Male 3/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 7/2/2007 62 Male 139 lb 6/14/2010 Other Health Professional Japan
Primary
Concomitant
Parkinson's Disease Hospitalization 59 Female 7/22/2010 Other Health Professional Japan
Primary
Concomitant
Dyshidrosis Death 7/18/2010 65 Male 8/2/2010 Physician Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 7/1/2010 62 Female 7/29/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2009 73 Female 101 lb 8/4/2010 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/1/2009 73 Female 101 lb 8/6/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Heat Illness Death 7/18/2010 65 Male 8/11/2010 Physician Japan
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 7/18/2010 62 Female 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Obsessive-compulsive Disorder Hospitalization 5/1/2010 61 Female 9/14/2010 Other Health Professional
Primary
Secondary
Obsessive-compulsive Disorder Other Serious 5/1/2010 61 Female 9/17/2010 Other Health Professional France
Primary
Secondary
Obsessive-compulsive Disorder Hospitalization 5/1/2010 61 Female 9/17/2010 Other Health Professional Denmark
Primary
Secondary
Sudden Onset Of Sleep Other Serious 7/16/2010 62 Female 128 lb 10/15/2010 Physician Japan
Primary
Concomitant
Interacting
Sudden Onset Of Sleep Other Serious 77 Female 12/16/2010 Other Health Professional Japan
Primary
Concomitant
Sudden Onset Of Sleep Other Serious 77 Female 12/30/2010 Other Health Professional Japan
Primary
Concomitant
Parkinson's Disease Hospitalization 3/1/2011 60 Male 3/17/2011 Physician Japan
Primary
Concomitant
Hallucination, Visual Other Serious 77 Female 3/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 3/5/2011 68 Female 3/24/2011 Other Health Professional Greece
Primary
Concomitant
Drug Administration Error Hospitalization 3/5/2011 68 Female 4/4/2011 Greece
Primary
Concomitant
Alcoholism Hospitalization 2/1/2007 54 Female 7/5/2011 Physician France
Primary
Concomitant

Drug Data