Co-Trimoxazole combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 1/1/2006 Female 168 lb 4/7/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 4/18/2006 Physician Germany
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 4/19/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/8/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/8/2006 Physician Germany
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 6/7/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 6/7/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 8/5/2006 59 Female 143 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 59 Female 143 lb 9/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 59 Female 143 lb 9/25/2006 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 43 Male 1/30/2007 United Kingdom
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 43 Male 3/9/2007 United Kingdom
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Required Intervention 1/4/2006 5 Female 35 lb 3/1/2007 Physician United States
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 11/1/1998 43 Male 3/21/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 3/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 3/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 4/2/2007 Other Health Professional Italy
Primary
Secondary
Thoracic Vertebral Fracture Other Serious 43 Male 3/27/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 4/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 4/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 4/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Hospitalization 11/1/1998 43 Male 4/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 78 Female 9/12/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 78 Female 9/17/2007 United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 5/2/2007 60 Male 175 lb 9/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 7/2/2007 53 Male 218 lb 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis B Life Threatening 2/14/2007 Male 218 lb 9/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Zygomycosis Other Serious 4/1/2003 40 Female 9/26/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Sepsis Other Serious 78 Female 10/1/2007 Consumer United States
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/1/1998 43 Male 10/26/2007 United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 5/2/2007 60 Male 175 lb 11/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 10/18/2007 Female 134 lb 1/10/2008 Physician Netherlands
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/24/2007 46 Female 146 lb 1/24/2008 United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Death Male 1/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/15/2008 Consumer United Kingdom
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 10/18/2007 Female 134 lb 2/20/2008 Physician Netherlands
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Hospitalization 1/1/2008 61 Female 169 lb 2/25/2008 France
Primary
Secondary
Concomitant
Toxic Skin Eruption 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Osteoporosis Other Serious 11/1/1998 43 Male 3/5/2008 United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Nocardiosis Other Serious 17 Male 3/12/2008 Other Health Professional Japan
Primary
Secondary
Hepatitis B Hospitalization 77 Female 3/12/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Nocardiosis Other Serious 17 Male 3/27/2008 Other Health Professional Japan
Primary
Secondary
Muscle Spasms Hospitalization 4/18/2008 Male 158 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 7/1/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 1/30/2008 75 Male 7/14/2008 Physician Greece
Primary
Concomitant
Respiratory Failure Other Serious 8/1/2003 76 Female 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Other Serious 11/1/1998 43 Male 8/6/2008 United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 1/1/1998 43 Male 8/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/1998 43 Male 8/12/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 1/1/1998 43 Male 8/20/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteoporosis Other Serious 11/1/1998 43 Male 8/20/2008 United Kingdom
Primary
Secondary
Concomitant
Skin Lesion Other Serious 8/1/2006 32 Female 8/19/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 11/1/1998 43 Male 8/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Fungal Death 76 Female 8/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/29/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Infection Death 51 6/14/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Mucosal Inflammation Death 6 40 lb 6/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2008 74 Female 10/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/28/2008 74 Female 10/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/4/2008 64 Male 220 lb 11/7/2008 Physician Australia
Primary
Concomitant
Pancytopenia Other Serious 74 Female 11/7/2008 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/28/2008 74 Female 11/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 74 Female 11/18/2008 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 10/31/2003 Female 2/11/2009 Other Health Professional Spain
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 26 Female 3/5/2009 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2009 11 Male 82 lb 3/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2009 11 Male 82 lb 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 82 lb 4/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2008 74 Female 4/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 84 lb 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 82 lb 5/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 8 Male 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypothyroidism Other Serious 15 5/12/2009 United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 134 lb 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 16 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 5/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 62 Male 5/29/2009
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 18 6/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Drug Ineffective Other Serious 3 6/1/2009 Physician United Kingdom
Primary
Secondary
Muscular Weakness Other Serious 1/1/2008 16 6/5/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Bile Duct Stenosis Other Serious 4 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Anti-thyroid Antibody Positive Other Serious 3 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Acute Graft Versus Host Disease In Skin Other Serious 1 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Cytomegalovirus Infection Other Serious 8 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Acute Graft Versus Host Disease Other Serious 2 6/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyperthyroidism Other Serious 14 6/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyperthyroidism Other Serious 14 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Hypothyroidism Other Serious 16 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 16 6/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 2 6/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Embolism Hospitalization 31 Male 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Soft Tissue Infection Other Serious 20 Female 7/2/2009 Other Health Professional Israel
Primary
Concomitant
Solitary Kidney Other Serious Female 11/9/2009 United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious Female 2 lb 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Solitary Kidney Other Serious Female 2 lb 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 11/30/2006 59 Female 137 lb 11/23/2009 United States
Primary
Concomitant
Solitary Kidney Other Serious Female 3 lb 11/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Application Site Cellulitis Hospitalization 11/8/2009 Male 171 lb 11/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/7/2009 Female 101 lb 11/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Solitary Kidney Other Serious Female 3 lb 12/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Premature Labour Other Serious 25 Female 12/3/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Solitary Kidney Other Serious Female 2 lb 12/3/2009 Other Health Professional Italy
Primary
Secondary
Solitary Kidney Other Serious Female 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Solitary Kidney Other Serious Female 3 lb 12/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Premature Labour Other Serious 25 Female 12/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/22/2009 Male 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 84 lb 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Injury Other Serious 49 Male 146 lb 1/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 7/30/2009 Male 154 lb 2/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 2/1/2010 Male 218 lb 3/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1/11/2010 Female 3/16/2010 Physician Italy
Primary
Secondary
Concomitant
Infection Hospitalization 12/16/2009 3/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Hospitalization 11/14/2010 82 Female 11/30/2010 Physician United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 7/15/2011 3 Female 29 lb 12/12/2012 Physician Gb
Primary
Secondary
Concomitant
Viral Infection Death 11 Male 8/31/2012 Other Health Professional Hk
Primary
Secondary
Concomitant
Viral Infection Other Serious 1 Female 8/31/2012 Other Health Professional Hk
Primary
Secondary
Concomitant
Viral Infection Other Serious 1 Male 9/5/2012 Other Health Professional Hk
Primary
Secondary
Concomitant
Fungal Sepsis Death 9/6/2012 Other Health Professional Ie
Primary
Concomitant
Venoocclusive Disease Death 9/7/2012 Other Health Professional Ie
Primary
Secondary
Concomitant
Neoplasm Recurrence Other Serious 9/18/2012 Other Health Professional Ie
Primary
Secondary
Concomitant
Juvenile Chronic Myelomonocytic Leukaemia Death 9/7/2012 Other Health Professional Ie
Primary
Concomitant
Bacterial Sepsis Death 9/13/2012 Other Health Professional Ie
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/28/2012 52 Female 151 lb 12/4/2012 Physician Gb
Primary
Secondary
Concomitant
Viral Infection Death 7/22/2010 11 Male 96 lb 12/11/2012 Other Health Professional Hk
Primary
Secondary
Concomitant

Drug Data