Clozaril combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Intentional Overdose Death 9/23/2005 33 Female 2/14/2006 Other Health Professional Australia
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 8/16/2006 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 10/24/2006 Pharmacist United Kingdom
Primary
Secondary
Fall Other Serious 9/1/2006 84 Male 11/9/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 11/10/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 10/14/2006 36 Female 12/1/2006 Physician Ireland
Primary
Concomitant
Weight Increased Hospitalization 6/1/2004 40 Male 12/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 6/1/2004 40 Male 4/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 8/1/2006 50 Male 4/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 5/31/2007 Pharmacist United Kingdom
Primary
Concomitant
Sedation Other Serious Female 6/24/2007 Physician New Zealand
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 36 Female 251 lb 7/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 1/4/2006 36 Female 7/5/2007
Primary
Concomitant
Sudden Death Death 1/4/2006 36 Female 7/11/2007 Other Health Professional United States
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/10/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 7/23/2007 Pharmacist United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/30/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 36 Female 7/12/2007 United Kingdom
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 7/9/2007 50 Male 320 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 8/29/2007 Physician United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 9/13/2007 Physician United Kingdom
Primary
Concomitant
Strabismus Other Serious 39 Male 1/21/2008 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/22/2008 Male 9/18/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/22/2008 Male 10/3/2008 Physician United Kingdom
Primary
Concomitant
Mastectomy Other Serious 8/15/2008 Female 10/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Intentional Self-injury Hospitalization Male 12/2/2008 Physician United Kingdom
Primary
Concomitant
Intentional Self-injury Hospitalization 8/1/2007 Male 12/29/2008 Physician United Kingdom
Primary
Concomitant
Intentional Self-injury Hospitalization 8/1/2007 Male 1/6/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 2/6/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 2/14/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 2/26/2009 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 1/5/2009 Female 3/3/2009 Physician Ireland
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 3/9/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 3/17/2009 Physician United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 2/8/2009 Female 96 lb 3/19/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 11/1/2008 Female 260 lb 4/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/25/2009 Male 4/9/2009 Physician New Zealand
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 2/1/2009 Female 4/10/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/23/2009 Male 4/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious Male 5/4/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 9/1/2002 Male 5/6/2009 Physician United Kingdom
Primary
Concomitant
Somnolence Hospitalization 1/6/2009 Female 5/13/2009 Pharmacist Canada
Primary
Concomitant
Salivary Hypersecretion Other Serious Male 5/26/2009 Pharmacist United Kingdom
Primary
Concomitant
Sedation Other Serious 1/1/2004 Male 5/26/2009 Other Health Professional Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 Female 205 lb 5/29/2009 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/1/2009 Pharmacist United Kingdom
Primary
Concomitant
Sedation Other Serious 1/1/2004 Male 6/4/2009 Other Health Professional Canada
Primary
Concomitant
Somnolence Other Serious 4/30/2009 Female 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 Female 6/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/1/2006 36 Female 6/24/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/22/2009 United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 Female 205 lb 6/29/2009 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/29/2009 Pharmacist United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 3/20/2009 Male 172 lb 7/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Stress Other Serious 6/3/2009 Female 7/23/2009 Physician New Zealand
Primary
Concomitant
Sexual Dysfunction Death 6/23/2008 Male 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious Male 8/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 8/21/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2009 Female 9/2/2009 Pharmacist Canada
Primary
Concomitant
Orthostatic Hypotension Other Serious 3/5/2009 Female 9/16/2009 Consumer United Kingdom
Primary
Concomitant
Viral Myocarditis Other Serious 41 Male 9/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Viral Myocarditis Death 41 Male 9/18/2009 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 1/21/2009 Male 9/24/2009 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 3/5/2009 Female 9/25/2009 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Death 41 Male 9/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization Male 9/29/2009 Physician United Kingdom
Primary
Secondary
Tachycardia Hospitalization Female 10/7/2009 Consumer United Kingdom
Primary
Concomitant
Sexual Dysfunction Other Serious 6/23/2008 Male 10/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/21/2009 Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 8/10/2009 Female 10/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 10/19/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/22/2009 Male 10/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization Female 10/22/2009 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Death 10/16/2009 Male 11/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 35 Female 11/4/2009 United Kingdom
Primary
Secondary
Platelet Count Increased Other Serious 12/16/2008 Female 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization Female 11/12/2009 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 Female 11/17/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Head Injury Other Serious 9/25/2009 Male 11/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 10/15/2009 Male 172 lb 11/20/2009 Physician Ireland
Primary
Concomitant
Urinary Tract Infection Required Intervention 5/12/2006 36 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/12/2006 36 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 10/15/2009 Male 172 lb 11/25/2009 Physician Ireland
Primary
Concomitant
Somnolence Other Serious 10/15/2009 Male 172 lb 11/27/2009 Physician Ireland
Primary
Concomitant
Tuberculosis Hospitalization Male 12/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 1/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/21/2004 Male 165 lb 1/29/2010 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 2/1/2009 Female 2/5/2010 Pharmacist Ireland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/16/2009 Male 2/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Other Serious 12/1/2007 Female 3/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/1/2009 Male 3/2/2010 Other Health Professional New Zealand
Primary
Concomitant
Ventricular Extrasystoles Other Serious 10/22/2009 Male 3/8/2010 Other Health Professional New Zealand
Primary
Concomitant
Suicidal Ideation Other Serious 11/30/2005 Male 238 lb 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Depression Other Serious Male 4/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Drug Administration Error Other Serious 3/20/2010 27 Male 254 lb 6/1/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2010 30 Male 172 lb 6/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization Female 8/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 6/25/2010 67 Male 8/20/2010 Physician United Kingdom
Primary
Concomitant
Gait Disturbance Hospitalization Female 8/30/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 7/5/2010 27 Male 9/2/2010 Physician United Kingdom
Primary
Concomitant
Poikilocytosis Hospitalization 8/11/2010 37 Male 9/13/2010 Consumer United Kingdom
Primary
Concomitant
Tooth Abscess Hospitalization 7/24/2010 36 Female 198 lb 9/15/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Respiratory Depression Death Male 9/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/11/2010 37 Male 9/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Thrombosis Other Serious Male 9/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious Female 10/1/2010 Other Health Professional New Zealand
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 6/25/2010 67 Male 10/8/2010 Physician United Kingdom
Primary
Concomitant
Oesophagitis Hospitalization 7/20/2010 66 Female 10/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alcohol Abuse Other Serious Male 10/14/2010 United Kingdom
Primary
Concomitant
Oesophagitis Hospitalization 7/20/2010 66 Female 10/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 5/27/2010 30 Male 10/28/2010 Physician United Kingdom
Primary
Concomitant
Oesophagitis Hospitalization 7/20/2010 66 Female 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 7/20/2010 66 Female 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 7/20/2010 66 Female 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 7/20/2010 66 Female 10/22/2010 Physician Denmark
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 7/20/2010 66 Female 10/28/2010 Other Health Professional
Primary
Secondary
Concomitant
Somnolence Other Serious 9/29/2010 48 Male 11/15/2010 Physician United Kingdom
Primary
Concomitant
Overdose Other Serious 7/22/2010 37 Male 11/30/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/30/2010 46 Male 12/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/20/2010 66 Female 12/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/20/2010 66 Female 12/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/20/2010 66 Female 1/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 7/20/2010 66 Female 1/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 7/20/2010 66 Female 1/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 10/30/2010 46 Male 1/5/2011 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/20/2010 66 Female 1/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Dizziness Hospitalization 7/20/2010 66 Female 12/30/2010 Physician Denmark
Primary
Concomitant
Dizziness Hospitalization 7/20/2010 66 Female 1/4/2011 Other Health Professional
Primary
Secondary
Concomitant
Oesophageal Ulcer Other Serious 7/20/2010 66 Female 1/18/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 7/20/2010 66 Female 1/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Hospitalization 7/20/2010 66 Female 1/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Hospitalization 7/20/2010 66 Female 1/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 7/20/2010 66 Female 1/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Eosinophil Count Increased Hospitalization 9/27/2010 54 Male 1/25/2011 Physician United Kingdom
Primary
Concomitant
Eosinophil Count Increased Death 9/27/2010 54 Male 1/28/2011 Physician United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 7/20/2010 66 Female 1/14/2011 Physician Denmark
Primary
Secondary
Concomitant
Gastrointestinal Ulcer Hospitalization 7/20/2010 66 Female 1/17/2011 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/20/2010 66 Female 1/20/2011 Other Health Professional
Primary
Secondary
Concomitant
Pyrexia Other Serious Male 2/22/2011 Physician New Zealand
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 10/30/2010 46 Male 2/24/2011 Pharmacist United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 3/28/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 4/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 3/14/2011 21 Male 170 lb 4/7/2011 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization 3/26/2011 51 Male 4/18/2011 Physician United Kingdom
Primary
Secondary
Overdose Other Serious 4/13/2011 33 Male 4/28/2011 Consumer United Kingdom
Primary
Secondary

Drug Data