Clozaril combined with Venlafaxine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 1/1/2008 Male 12/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious Male 1/6/2009 Physician Ireland
Primary
Concomitant
Stress Hospitalization 1/1/2009 Male 179 lb 1/28/2009 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 3/27/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/8/2009 Male 5/25/2009 Physician United Kingdom
Primary
Concomitant
Testis Cancer Other Serious Male 9/29/2009 Physician Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/10/2009 Female 10/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 8/10/2009 Female 10/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 10/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious Male 10/21/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/4/2007 44 Female 10/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/4/2007 44 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 5/7/2009 33 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/1/2009 Male 10/28/2009 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 44 Female 10/27/2009 Physician
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 11/4/2009 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 11/10/2009 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 11/11/2009 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2009 Female 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 11/16/2009 Pharmacist Ireland
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 7/1/2008 Female 11/17/2009 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 9/1/2009 Male 11/27/2009 Other Health Professional Ireland
Primary
Concomitant
Somnolence Other Serious 10/8/2009 Female 12/3/2009 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 12/4/2009 Pharmacist Ireland
Primary
Concomitant
Orthostatic Hypotension Hospitalization 10/1/2009 Female 12/14/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Schizophrenia, Catatonic Type Hospitalization 2/1/2008 57 Male 12/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 10/17/2008 Male 216 lb 12/17/2009 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 12/28/2009 Pharmacist Ireland
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 7/1/2008 Female 12/29/2009 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 9/8/2009 Male 12/29/2009 Pharmacist United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 10/1/2009 57 Female 12/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 10/12/2009 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 1/15/2010 Pharmacist Ireland
Primary
Concomitant
Respiratory Tract Infection Other Serious Male 1/22/2010 Physician Ireland
Primary
Concomitant
Somnolence Other Serious 10/8/2009 Female 1/25/2010 Other Health Professional Ireland
Primary
Concomitant
Atrial Flutter Other Serious Female 2/5/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/5/2009 Female 2/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Infection Other Serious Male 2/9/2010 Physician Ireland
Primary
Concomitant
Mental Impairment Other Serious Male 2/12/2010 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 12/5/2009 32 Male 2/12/2010 Other Health Professional France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 8/28/2009 Female 2/22/2010 Pharmacist Ireland
Primary
Concomitant
Sinus Tachycardia Other Serious 10/6/2009 Female 2/25/2010 Physician New Zealand
Primary
Concomitant
Hypotension Other Serious 12/1/2007 Female 3/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/1/2009 Male 3/8/2010 Other Health Professional Ireland
Primary
Concomitant
Somnolence Other Serious 2/1/2010 Male 3/9/2010 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 11/30/2005 Male 238 lb 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Life Threatening 1/29/2010 Male 3/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 4/6/2010 Physician Australia
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 4/26/2010 Other Health Professional Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/4/2002 38 Male 4/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Drug Toxicity Other Serious 5/7/2009 33 Female 5/7/2010 Physician United Kingdom
Primary
Concomitant
Interacting
Death Death 4/5/2010 40 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 2/1/2010 51 Male 5/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 2/1/2010 44 Male 187 lb 5/21/2010 Physician United Kingdom
Primary
Concomitant
Drug Toxicity Other Serious 5/7/2009 33 Female 5/24/2010 Physician United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 5/26/2010 Other Health Professional Australia
Primary
Concomitant
Drug Toxicity Other Serious 5/7/2009 33 Female 5/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 11/1/2005 50 Female 5/27/2010 Other Health Professional Canada
Primary
Concomitant
Hypertension Death Male 5/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 6/2/2010 Other Health Professional Australia
Primary
Concomitant
Tachycardia Other Serious 9/25/2009 25 Male 6/8/2010 Other Health Professional Ireland
Primary
Concomitant
Vomiting Other Serious 5/5/2010 43 Male 6/17/2010 United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 2/1/2010 44 Male 187 lb 6/24/2010 Physician United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 12/29/2009 34 Male 6/25/2010 Physician Australia
Primary
Concomitant
Drug Toxicity Other Serious 5/7/2009 33 Female 6/25/2010 Physician United Kingdom
Primary
Concomitant
Interacting
Syncope Other Serious 12/5/2009 32 Male 7/9/2010 Physician United Kingdom
Primary
Secondary
Syncope Other Serious 12/20/2009 55 Female 7/15/2010 Other Health Professional Ireland
Primary
Concomitant
Syncope Other Serious 12/5/2009 32 Male 7/20/2010 Physician United Kingdom
Primary
Secondary
Drug Toxicity Other Serious 5/7/2009 33 Female 7/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Toxicity Other Serious 5/7/2009 33 Female 7/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Toxicity Other Serious 5/7/2009 33 Female 7/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Toxicity Other Serious 5/7/2009 33 Female 7/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 44 Female 7/15/2010 Physician
Primary
Secondary
Concomitant
Bipolar Disorder Other Serious Male 8/2/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/1/2010 59 Male 8/2/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Hospitalization Male 8/5/2010 Pharmacist United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death 4/7/2010 40 Male 8/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 12/29/2009 34 Male 8/16/2010 Australia
Primary
Concomitant
Injury Other Serious 5/25/2010 41 Male 8/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 7/11/2010 55 Female 8/25/2010 Other Health Professional Ireland
Primary
Concomitant
Syncope Other Serious 5/7/2009 33 Female 8/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Depressed Mood Death 8/7/2010 36 Male 182 lb 8/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2010 59 Male 9/8/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/25/2010 47 Male 187 lb 9/13/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 7/11/2010 55 Female 9/13/2010 Other Health Professional Ireland
Primary
Concomitant
Anal Abscess Hospitalization 5/21/2010 35 Male 9/16/2010 Physician United Kingdom
Primary
Concomitant
Pancreatitis Other Serious 8/1/2006 56 Male 185 lb 9/17/2010 United States
Primary
Concomitant
Drug Toxicity Other Serious 5/7/2009 33 Female 9/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Orthostatic Hypotension Other Serious 2/1/2010 44 Male 187 lb 10/20/2010 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization Male 10/25/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/29/2010 37 Female 10/27/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Death Female 10/29/2010 Other Health Professional Canada
Primary
Concomitant
Neutrophil Count Increased Other Serious 7/26/2010 43 Male 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 45 Male 11/8/2010 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/17/2010 11/10/2010 Physician Ireland
Primary
Concomitant
Suicide Attempt Hospitalization Female 11/10/2010 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 10/12/2010 46 Male 11/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/17/2010 34 Female 287 lb 11/17/2010 Physician Ireland
Primary
Concomitant
Platelet Count Decreased Other Serious 8/31/2010 36 Female 11/24/2010 Physician Ireland
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 45 Male 11/29/2010 Pharmacist Ireland
Primary
Concomitant
Overdose Other Serious 7/22/2010 37 Male 11/30/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 10/12/2010 46 Male 12/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization Female 12/7/2010 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 10/12/2010 46 Male 12/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Life Threatening 10/1/1999 75 Female 12/21/2010 Australia
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization Male 309 lb 12/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization Male 1/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Toxicity To Various Agents Other Serious 5/7/2009 33 Female 1/5/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Cyanosis Death 5/7/2009 33 Female 172 lb 1/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious 8/17/2010 34 Female 287 lb 1/19/2011 Physician Ireland
Primary
Concomitant
Anticonvulsant Drug Level Increased Other Serious 5/7/2009 33 Female 1/19/2011 Physician United Kingdom
Primary
Concomitant
Interacting
Vomiting Death 5/7/2009 33 Female 1/19/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
General Physical Condition Abnormal Other Serious 7/26/2010 43 Male 1/20/2011 Physician United Kingdom
Primary
Concomitant
Constipation Death Male 1/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Increased Other Serious 10/1/2010 41 Male 2/1/2011 Physician United Kingdom
Primary
Concomitant
Dyspepsia Hospitalization 12/22/2010 58 Male 2/4/2011 Physician United Kingdom
Primary
Concomitant
Tongue Biting Other Serious 1/4/2011 36 Female 2/4/2011 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Increased Other Serious 1/6/2011 39 Male 198 lb 2/8/2011 Physician United Kingdom
Primary
Concomitant
Constipation Hospitalization Male 2/8/2011 Physician United Kingdom
Primary
Concomitant
Haematemesis Hospitalization 12/22/2010 58 Male 2/4/2011 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 5/7/2009 33 Female 172 lb 2/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Syncope Other Serious 5/7/2009 33 Female 172 lb 2/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Hidradenitis Other Serious 8/17/2010 34 Female 287 lb 2/15/2011 Physician Ireland
Primary
Concomitant
Neutrophil Count Increased Other Serious 1/6/2011 39 Male 198 lb 2/16/2011 Physician United Kingdom
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2003 22 Female 247 lb 2/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 8/31/2010 36 Female 2/28/2011 Physician Ireland
Primary
Concomitant
Obesity Hospitalization Male 3/1/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/30/2010 52 Female 3/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 1/1/2008 45 Male 3/17/2011 Other Health Professional Ireland
Primary
Concomitant
Lethargy Other Serious Female 3/29/2011 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 12/20/2009 55 Female 3/30/2011 Physician Ireland
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/30/2010 52 Female 4/28/2011 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 10/12/2010 46 Male 5/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Monocyte Count Increased Other Serious 2/15/2011 49 Female 5/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 10/12/2010 46 Male 5/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization Male 5/20/2011 Physician United Kingdom
Primary
Concomitant
Abdominal Distension Life Threatening Male 5/20/2011 Physician United Kingdom
Primary
Concomitant
Altered State Of Consciousness Other Serious 4/22/2011 32 Female 5/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 4/26/2011 38 Female 5/25/2011 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 10/12/2010 46 Male 5/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Mass Hospitalization 2/22/2011 72 Male 5/25/2011 Physician United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious Male 6/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious Male 6/7/2011 Consumer United Kingdom
Primary
Concomitant
Heat Illness Death 6/29/2005 54 Male 6/3/2011 Physician Canada
Primary
Concomitant
Hypotension Other Serious 6/24/2005 30 Male 6/3/2011 Physician United Kingdom
Primary
Concomitant
Pneumonia Death Female 6/9/2011 Physician United Kingdom
Primary
Concomitant
Completed Suicide Death 11/18/2002 65 Male 6/12/2011 Consumer United Kingdom
Primary
Concomitant
Death Death Male 10/17/2011 Other Health Professional Ireland
Primary
Secondary
Concomitant
Social Avoidant Behaviour Other Serious 9/1/2010 38 Female 123 lb 10/19/2011 Physician Ireland
Primary
Secondary
Concomitant

Drug Data