Clozaril combined with Risperidone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Splenomegaly Other Serious 5/13/2005 62 Male 250 lb 2/10/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 2/6/2006 37 Male 2/17/2006 Physician Australia
Primary
Concomitant
Ventricular Hypokinesia Other Serious 2/6/2006 37 Male 2/22/2006 Physician Australia
Primary
Concomitant
Ventricular Hypokinesia Other Serious 2/7/2006 37 Male 3/7/2006 Physician Australia
Primary
Concomitant
Ventricular Hypokinesia Other Serious 2/7/2006 37 Male 4/5/2006 Physician Australia
Primary
Concomitant
Road Traffic Accident Death 10/30/2005 42 Male 4/5/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 12/18/1998 26 Male 243 lb 4/1/2006 Lawyer United States
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 12/23/1999 42 Female 4/25/2006 Physician Australia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/29/2006 64 Male 8/9/2006 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 7/29/2006 64 Male 8/25/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/1/2004 20 Male 10/11/2006 United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/1/2004 20 Male 11/23/2006 United Kingdom
Primary
Concomitant
Somnolence Other Serious 53 Female 11/28/2006 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Aspiration Other Serious 11/18/2006 32 Female 12/16/2006 Pharmacist United Kingdom
Primary
Concomitant
Tremor Other Serious 1/1/1998 64 Female 179 lb 12/22/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 11/16/2006 53 Female 12/27/2006 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/4/2005 Female 1/26/2007 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 65 Male 3/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 53 Male 5/10/2007 Physician Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/16/2002 40 Female 5/26/2007 Physician Canada
Primary
Secondary
Concomitant
Metabolic Disorder Other Serious 1/1/1997 42 Male 195 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Metabolic Disorder Hospitalization 1/1/2006 39 Female 225 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 11/1/2004 20 Male 7/7/2007 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 7/1/2007 32 Male 8/8/2007 Pharmacist United Kingdom
Primary
Concomitant
Tachycardia Other Serious 7/18/2006 30 Male 10/10/2007 Other Health Professional United Kingdom
Primary
Interacting
Vomiting Other Serious 11/1/2004 23 Male 11/15/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/1/2004 23 Male 11/15/2007 United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/4/2007 34 Male 11/20/2007 Physician Australia
Primary
Concomitant
Metabolic Disorder Other Serious 5/1/2003 39 Female 192 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 12/9/2007 28 Male 12/24/2007 Physician United Kingdom
Primary
Secondary
Interacting
White Blood Cell Count Increased Hospitalization 10/6/2007 36 Male 12/28/2007 Physician Australia
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 12/9/2007 28 Male 12/28/2007 Physician United Kingdom
Primary
Secondary
Interacting
Pulmonary Embolism Hospitalization 11/1/2007 33 Male 12/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Obstruction Other Serious 8/1/2007 Male 1/30/2008 Other Health Professional New Zealand
Primary
Concomitant
Urinary Tract Obstruction Other Serious 8/1/2007 Male 2/19/2008 Other Health Professional New Zealand
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 2/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Vomiting Other Serious 3/3/2008 20 Female 205 lb 3/18/2008 Physician New Zealand
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 4/29/2005 24 Female 5/1/2008 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/29/2005 24 Female 5/10/2008 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/11/2007 Male 176 lb 5/27/2008 Consumer Ireland
Primary
Concomitant
Troponin T Increased Other Serious 5/12/2005 Male 7/4/2008 Other Health Professional Australia
Primary
Concomitant
Somnolence Other Serious 11/30/2007 Male 172 lb 7/7/2008 Other Health Professional Ireland
Primary
Concomitant
Thrombocytopenia Other Serious 44 Male 196 lb 7/11/2008 Physician Canada
Primary
Secondary
Concomitant
Surgery Life Threatening 1/16/2003 Male 7/16/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 3/3/2008 Female 205 lb 7/23/2008 Pharmacist New Zealand
Primary
Concomitant
Vomiting Other Serious 5/12/2005 Male 7/28/2008 Pharmacist Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/11/2008 Male 8/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Postural Orthostatic Tachycardia Syndrome Other Serious 9/18/2008 Male 10/16/2008 Physician Canada
Primary
Concomitant
Mastectomy Other Serious 8/15/2008 Female 10/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 10/6/2008 Female 11/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Postural Orthostatic Tachycardia Syndrome Other Serious 9/18/2008 Male 11/14/2008 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 Male 11/25/2008 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 11/5/2008 Male 12/1/2008 Other Health Professional Ireland
Primary
Concomitant
Pulmonary Congestion Other Serious Male 12/1/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/11/2007 Male 176 lb 12/3/2008 Consumer Ireland
Primary
Concomitant
Fall Hospitalization 10/3/2008 Male 12/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Excision Other Serious 8/23/2007 Male 12/11/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 7/7/2008 Male 2/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Disorder Other Serious 28 Male 2/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/19/2008 Male 2/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Death 10/4/2008 44 Female 225 lb 2/9/2009 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious 1/23/2009 Male 3/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Congestion Other Serious Male 3/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Completed Suicide Death 3/14/2009 Male 3/26/2009 Other Health Professional Canada
Primary
Concomitant
Syncope Other Serious 4/28/2000 Male 3/27/2009 Physician Australia
Primary
Concomitant
Troponin Increased Hospitalization 2/21/2009 Male 3/31/2009 Pharmacist Australia
Primary
Concomitant
Somnolence Hospitalization 1/1/2008 Female 4/4/2009 Pharmacist United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 1/23/2009 Male 4/8/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 4/28/2000 Male 4/8/2009 Physician Australia
Primary
Concomitant
Syncope Other Serious 4/28/2000 Male 4/8/2009 Physician Australia
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 40 Male 305 lb 4/17/2009 United States
Primary
Concomitant
Viral Infection Other Serious 12/27/2007 Male 4/23/2009 Other Health Professional Ireland
Primary
Secondary
Viral Infection Other Serious 12/27/2007 Male 4/27/2009 Other Health Professional France
Primary
Secondary
Viral Infection Other Serious 12/27/2007 41 Male 4/27/2009 Physician Ireland
Primary
Secondary
Psychotic Disorder Other Serious Male 5/4/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 9/1/2002 Male 5/6/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 7/1/2008 Female 5/11/2009 Physician United Kingdom
Primary
Concomitant
Salivary Hypersecretion Other Serious Male 5/26/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/13/2009 Male 6/3/2009 Physician Australia
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/13/2009 Male 6/11/2009 Physician Australia
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 3/23/2009 Male 6/18/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/13/2009 Male 7/2/2009 Other Health Professional Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/20/2009 Female 7/2/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/8/2009 Female 7/6/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/20/2009 Female 7/7/2009 Physician United Kingdom
Primary
Concomitant
Sudden Cardiac Death Death Female 7/13/2009 Other Health Professional Ireland
Primary
Concomitant
Troponin T Increased Other Serious 4/20/2009 Male 7/16/2009 Other Health Professional Australia
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2006 42 Female 190 lb 7/17/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/23/2009 Male 7/24/2009 Pharmacist Australia
Primary
Concomitant
Weight Increased 4/28/1999 Female 250 lb 7/24/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization Male 7/27/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/1/2009 Male 8/10/2009 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Bundle Branch Block Right Other Serious 10/27/2008 Male 8/10/2009 Physician Australia
Primary
Concomitant
Extrapyramidal Disorder Hospitalization Male 8/11/2009 Consumer United Kingdom
Primary
Secondary
Bundle Branch Block Right Other Serious 10/27/2008 Male 8/13/2009 Physician Australia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2009 Male 8/25/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious Male 251 lb 8/25/2009 Physician Australia
Primary
Concomitant
Somnolence Hospitalization Male 9/1/2009 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/6/2005 46 Female 238 lb 9/2/2009 United States
Primary
Concomitant
Weight Increased Other Serious Male 251 lb 9/3/2009 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 3/1/2009 Female 9/4/2009 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/16/2002 62 Male 9/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Diabetic Ketoacidosis Other Serious Female 194 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/13/2009 Male 9/30/2009 Other Health Professional Australia
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Mental Impairment Other Serious 9/14/2009 Female 10/20/2009 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Hospitalization 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/20/2008 35 Male 10/26/2009 Physician United Kingdom
Primary
Concomitant
Mental Impairment Other Serious 9/14/2009 Female 10/27/2009 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious Female 10/22/2009 United Kingdom
Primary
Concomitant
Weight Increased Other Serious 4/18/2002 50 Male 243 lb 10/28/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/1/2007 60 Male 11/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Salivary Hypersecretion Other Serious Male 11/3/2009 New Zealand
Primary
Concomitant
Platelet Count Increased Other Serious 5/1/2007 60 Male 11/2/2009 United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 5/1/2007 60 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Salivary Hypersecretion Other Serious Male 11/18/2009 New Zealand
Primary
Concomitant
Pneumonia Other Serious 9/1/2009 Male 11/23/2009 Other Health Professional Canada
Primary
Concomitant
Platelet Count Increased Other Serious 60 Male 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Arrest Hospitalization 9/24/2009 Male 11/24/2009 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/29/2005 Female 12/3/2009 Physician Australia
Primary
Concomitant
Salivary Hypersecretion Other Serious Male 12/18/2009 New Zealand
Primary
Concomitant
Tachycardia Other Serious 4/23/2008 42 Male 12/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 11/29/2009 Male 12/23/2009 Physician Ireland
Primary
Concomitant
Tachycardia Other Serious 4/23/2008 42 Male 12/17/2009 United Kingdom
Primary
Concomitant
Tachycardia Life Threatening 10/6/2009 Female 12/29/2009 Consumer Australia
Primary
Concomitant
Schizophrenia Hospitalization Male 12/30/2009 Pharmacist Australia
Primary
Concomitant
Hyperthyroidism Other Serious Male 12/30/2009 Physician Ireland
Primary
Concomitant
Haemolytic Anaemia Other Serious Female 12/31/2009 Physician Canada
Primary
Concomitant
Tachycardia Other Serious 42 Male 12/24/2009 United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 11/9/2000 Male 1/7/2010 Physician Australia
Primary
Concomitant
Hyperthyroidism Hospitalization Male 1/12/2010 Physician Ireland
Primary
Concomitant
Death Other Serious Male 1/15/2010 Other Health Professional Canada
Primary
Concomitant
Wheezing Other Serious 11/9/2000 Male 1/15/2010 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 4/18/2002 50 Male 243 lb 1/21/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/20/2009 Female 1/25/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/21/2004 Male 165 lb 1/29/2010 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/1/2009 Female 2/3/2010 Physician United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 11/5/2009 Female 3/5/2010 Physician Ireland
Primary
Concomitant
Somnolence Other Serious 2/1/2010 Male 3/9/2010 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 11/5/2009 Male 191 lb 3/12/2010 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/15/2008 Female 3/23/2010 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 4/18/2002 50 Male 243 lb 4/8/2010 United States
Primary
Concomitant
Tachycardia Other Serious 11/5/2009 31 Male 191 lb 4/21/2010 Other Health Professional Ireland
Primary
Concomitant
Weight Decreased Other Serious 8/1/2009 29 Male 4/23/2010 Physician Ireland
Primary
Concomitant
Weight Decreased Other Serious 8/1/2009 29 Male 4/28/2010 Physician Ireland
Primary
Concomitant

Drug Data