Clozaril combined with Ranitidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Hospitalization 1/1/2003 69 Female 159 lb 1/19/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/1999 23 Male 331 lb 8/1/2006 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 3/25/2006 43 Male 10/10/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/25/2006 43 Male 10/12/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 11/3/2006 48 Male 11/9/2006 Canada
Primary
Secondary
Concomitant
Sudden Death Death 7/20/2000 38 Female 12/4/2006 Consumer Australia
Primary
Secondary
Urinary Incontinence Other Serious 49 Male 298 lb 12/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Gastrointestinal Obstruction Hospitalization 10/13/1980 52 Male 12/22/2006 Canada
Primary
Concomitant
Somnolence Other Serious 11/16/2006 53 Female 12/27/2006 Pharmacist United Kingdom
Primary
Concomitant
Intestinal Functional Disorder Other Serious 10/13/1980 52 Male 2/13/2007 Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 31 Male 5/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 31 Male 5/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 31 Male 5/9/2007 United Kingdom
Primary
Concomitant
Pneumonia Other Serious 31 Male 5/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Death 8/1/2007 26 Male 1/9/2008 Physician Australia
Primary
Secondary
Thrombocytopenia Hospitalization 6/1/2007 27 Male 1/11/2008 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 6/1/2007 27 Male 1/16/2008 Physician
Primary
Secondary
Thrombocytopenia Hospitalization 6/4/2007 27 Male 1/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 6/4/2007 27 Male 1/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 6/4/2007 27 Male 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Death Male 11/10/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 1/27/2009 Female 3/2/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/27/2009 Female 3/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 2/17/2009 Male 4/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/17/2009 Male 5/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Death 4/5/2009 Male 5/11/2009 Physician New Zealand
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/17/2009 Male 6/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 4/7/2006 51 Female 156 lb 6/3/2009 United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 1/23/2003 42 Female 224 lb 6/29/2009 United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2000 21 Female 172 lb 7/9/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 10/20/2000 53 Female 207 lb 7/9/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 47 Male 283 lb 7/21/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/18/2003 52 Male 201 lb 8/28/2009 United States
Primary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious 8/17/2009 Male 9/11/2009 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 10/1/2003 26 Male 385 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 51 Female 166 lb 9/23/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 39 Male 198 lb 10/6/2009 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization Male 12/18/2009 Physician United Kingdom
Primary
Concomitant
Metastatic Neoplasm Other Serious Male 1/7/2010 Physician United Kingdom
Primary
Concomitant
Post Procedural Infection Hospitalization Male 1/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Neoplasm Other Serious Male 2/16/2010 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 Male 3/12/2010 Pharmacist United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/20/2010 77 Male 151 lb 4/1/2010 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 4/6/2010 Physician Australia
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 56 Male 4/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 56 Male 4/21/2010 Pharmacist United Kingdom
Primary
Concomitant
Breast Cancer Metastatic Life Threatening 1/1/2010 67 Female 4/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 4/26/2010 Other Health Professional Australia
Primary
Concomitant
Syncope Other Serious 12/29/2009 58 Male 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Infection Hospitalization Male 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Metastatic Life Threatening 1/1/2010 67 Female 4/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Infection Hospitalization Male 5/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 4/12/2010 72 Male 5/21/2010 United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 5/26/2010 Other Health Professional Australia
Primary
Concomitant
Wound Other Serious Male 6/2/2010 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2009 72 Female 230 lb 6/2/2010 Other Health Professional Australia
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/18/2003 52 Male 198 lb 6/10/2010 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 4/12/2010 72 Male 6/14/2010 United Kingdom
Primary
Concomitant
Wound Other Serious Male 6/14/2010 Physician United Kingdom
Primary
Concomitant
Sinus Arrhythmia Other Serious 11/1/2009 65 Female 6/18/2010 Pharmacist Australia
Primary
Concomitant
Water Intoxication Hospitalization 4/30/2010 55 Male 7/27/2010 Pharmacist United Kingdom
Primary
Concomitant
Schizophrenia Other Serious 5/5/2010 70 Female 7/29/2010 Physician Canada
Primary
Concomitant
Wheezing Other Serious 1/9/2004 41 Female 285 lb 8/11/2010 United States
Primary
Concomitant
Water Intoxication Hospitalization 4/30/2010 55 Male 8/25/2010 Pharmacist United Kingdom
Primary
Concomitant
Wheezing Other Serious 3/1/2004 42 Female 285 lb 9/3/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 25 Female 261 lb 9/3/2010 United States
Primary
Concomitant
Platelet Count Increased Other Serious 6/1/2010 48 Female 9/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/20/2010 United States
Primary
Concomitant
Tachycardia Other Serious 8/3/2010 41 Male 9/23/2010 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 56 Male 9/23/2010 Pharmacist United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 4/12/2010 72 Male 9/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 6/1/2010 48 Female 9/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious Female 10/13/2010 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 8/31/2010 44 Male 10/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 10/21/2010 56 Female 12/15/2010 Physician Canada
Primary
Concomitant
Ankle Fracture Hospitalization 11/20/2010 63 Female 1/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Eosinophil Count Increased Other Serious 8/17/2010 30 Male 1/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 8/18/2003 52 Male 198 lb 1/19/2011 United States
Primary
Concomitant
Eosinophil Count Increased Other Serious 8/17/2010 30 Male 1/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Arrest Death 1/14/2011 58 Male 1/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyperhidrosis Other Serious 11/15/2004 42 Female 285 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Malaise Other Serious 1/20/2011 62 Male 3/7/2011 Consumer Australia
Primary
Concomitant
Hyperlipidaemia Other Serious 11/15/2004 42 Female 285 lb 3/10/2011 Consumer United States
Primary
Concomitant
Blood Cholesterol Increased Other Serious 11/15/2004 42 Female 285 lb 3/28/2011 Consumer United States
Primary
Concomitant
Diabetic Complication Other Serious 11/15/2004 42 Female 285 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/8/2011 41 Male 4/6/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Other Serious 1/1/2009 70 Female 4/11/2011 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/8/2011 41 Male 4/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 4/1/2011 59 Male 157 lb 4/29/2011 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 2/18/2003 50 Male 6/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Death 2/5/2005 86 Female 6/4/2011 Physician Canada
Primary
Concomitant
Neoplasm Malignant Death 3/23/2005 59 Male 6/4/2011 Other Health Professional Canada
Primary
Concomitant
Intestinal Obstruction Death 4/26/2003 54 Female 6/11/2011 Pharmacist Australia
Primary
Concomitant
Sedation Death Male 6/15/2011 Consumer United Kingdom
Primary
Concomitant
Bradycardia Hospitalization 3/1/2011 58 Male 10/14/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/6/2011 72 Female 154 lb 10/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophilia Other Serious 7/1/2011 49 Female 10/27/2011 Physician Ireland
Primary
Concomitant
General Physical Health Deterioration Hospitalization 1/1/2009 70 Female 10/31/2011 Physician United Kingdom
Primary
Concomitant
Osteoarthritis Other Serious Female 154 lb 10/31/2011 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/8/2011 41 Male 10/31/2011 Physician United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 7/11/2011 85 Female 11/2/2011 Physician United Kingdom
Primary
Concomitant
Neutrophilia Other Serious 1/1/2010 47 Female 11/30/2011 Other Health Professional Ireland
Primary
Concomitant
Postictal State Other Serious 7/1/2011 45 Female 1/3/2012 Other Health Professional Australia
Primary
Concomitant
Malaise Hospitalization 2/3/2012 41 Male 3/14/2012 Pharmacist Australia
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/31/2009 31 Male 4/2/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Sedation Disability 1/1/2011 72 Female 176 lb 4/13/2012 Physician United Kingdom
Primary
Concomitant
Oesophageal Rupture Other Serious 11/21/2011 46 Male 4/14/2012 Physician United Kingdom
Primary
Concomitant
Troponin Increased Other Serious 2/13/2012 65 Female 4/14/2012 Physician United Kingdom
Primary
Concomitant
Lower Limb Fracture Other Serious 11/20/2010 63 Female 4/14/2012 Other Health Professional United Kingdom
Primary
Concomitant
Sedation Other Serious 1/1/2011 72 Female 176 lb 5/4/2012 Other Health Professional United Kingdom
Primary
Concomitant
Lower Limb Fracture Hospitalization 11/20/2010 63 Female 5/23/2012 Pharmacist United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/31/2012 64 Female 196 lb 5/23/2012 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 2/2/2012 78 Female 220 lb 5/24/2012 Pharmacist Australia
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/2/2012 78 Female 220 lb 5/24/2012 Pharmacist Australia
Primary
Secondary
Concomitant
Ankle Fracture Other Serious 11/20/2010 63 Female 6/12/2012 Pharmacist United Kingdom
Primary
Concomitant
Muscle Spasms Other Serious 12/2/2003 37 Male 267 lb 6/18/2012 Physician New Zealand
Primary
Concomitant
Ear Infection Other Serious 2/2/2012 78 Female 220 lb 6/22/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 2/2/2012 78 Female 220 lb 6/22/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Anaemia Of Chronic Disease Other Serious 7/11/2011 85 Female 7/6/2012 Physician United Kingdom
Primary
Concomitant
Bone Pain Other Serious 10/31/2009 31 Male 7/6/2012 Physician United Kingdom
Primary
Concomitant
Testicular Mass Other Serious 8/17/2010 30 Male 7/6/2012 Other Health Professional United Kingdom
Primary
Concomitant
Squamous Cell Carcinoma Other Serious Male 7/11/2012 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Increased Other Serious 10/31/2009 31 Male 7/12/2012 Physician United Kingdom
Primary
Concomitant
Splenomegaly Other Serious 10/31/2009 31 Male 7/12/2012 Physician United Kingdom
Primary
Concomitant
Ulcer Other Serious 4/24/2012 75 Female 7/24/2012 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 41 Female 230 lb 7/26/2012 Consumer United States
Primary
Concomitant
Neutrophil Count Increased Other Serious 8/17/2010 30 Male 8/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/31/2009 31 Male 8/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/2009 Male 3/22/2013 Pharmacist Gb
Primary
Concomitant
Tibia Fracture Hospitalization 11/20/2010 63 Female 3/28/2013 Pharmacist Gb
Primary
Concomitant
Testicular Mass Other Serious 9/10/2012 32 Male 9/27/2012 Other Health Professional Gb
Primary
Concomitant
Neoplasm Malignant Hospitalization 4/18/2012 32 Male 9/16/2012 Other Health Professional Ie
Primary
Concomitant
Somnolence Hospitalization Male 11/22/2012 Other Health Professional Gb
Primary
Concomitant
Skin Infection Hospitalization 11/17/2011 28 Male 10/29/2012 Pharmacist Au
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 10/25/2012 56 Male 10/28/2013 Other Health Professional Gb
Primary
Concomitant
Pyrexia Other Serious 11/5/2012 54 Male 12/6/2012 Other Health Professional Au
Primary
Concomitant
Weight Decreased Disability 5/27/2011 31 Male 187 lb 3/7/2013 Other Health Professional Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/11/2012 43 Male 1/29/2013 Physician Gb
Primary
Concomitant
Prothrombin Time Shortened Other Serious 2006 73 Male 154 lb 8/5/2013 Physician Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/15/2013 56 Female 3/29/2013 Physician Gb
Primary
Concomitant
Vomiting Hospitalization 1/7/2013 51 Female 9/25/2013 Physician Ie
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/5/2013 66 Female 10/11/2013 Physician Gb
Primary
Concomitant
Systemic Inflammatory Response Syndrome Other Serious 3/2013 48 Male 7/12/2013 Physician Gb
Primary
Concomitant
Death Death 7/15/2013 49 Male 8/29/2013 Other Health Professional Ca
Primary
Concomitant
Death Death 7/14/2013 75 Female 10/16/2013 Other Health Professional Ca
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2012 58 Male 10/7/2013 Physician Us
Primary
Concomitant
Thinking Abnormal Hospitalization 3/9/2012 46 Female 10/28/2013 Other Health Professional Au
Primary
Concomitant
Urinary Tract Infection Other Serious 3/25/2013 53 Female 152 lb 11/19/2013 Physician Gb
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/2/2012 78 Female 220 lb 9/6/2012 Physician Au
Primary
Secondary
Concomitant

Drug Data