Clozaril combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Exercise Tolerance Decreased Hospitalization 28 Male 1/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 4/20/2006 52 Female 7/25/2006 Pharmacist United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 11/1/2006 37 Female 11/18/2006 Pharmacist Australia
Primary
Concomitant
Hysterectomy Other Serious 11/1/2006 43 Female 3/10/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/12/2006 46 Male 3/23/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Troponin I Increased Hospitalization 4/12/2007 Female 1/23/2009 Physician Australia
Primary
Concomitant
Resuscitation Other Serious 1/12/2009 Male 2/3/2009 Physician Canada
Primary
Concomitant
Overdose Hospitalization 2/17/2009 Male 3/4/2009 Pharmacist United Kingdom
Primary
Secondary
Urinary Incontinence Other Serious 12/15/2008 Female 3/6/2009 Canada
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/1/2001 Female 3/26/2009 Physician United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 5/5/2006 59 Male 257 lb 6/2/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 5/16/2009 Male 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Hospitalization 1/15/2009 Male 7/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization Male 205 lb 7/27/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/5/2009 Female 7/31/2009 Pharmacist United Kingdom
Primary
Concomitant
Insulin Resistance Other Serious 1/1/2005 31 Female 131 lb 8/12/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Tachycardia Hospitalization Female 10/7/2009 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2009 Female 10/22/2009 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 52 Female 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/13/2008 52 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Hospitalization 1/15/2009 61 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 11/2/2009 United States
Primary
Concomitant
Weight Decreased Other Serious Male 11/6/2009 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/6/2009 Other Health Professional
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 69 Female 12/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2009 Male 12/9/2009 Consumer United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 69 Female 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 10/6/2009 Female 12/29/2009 Consumer Australia
Primary
Concomitant
Urinary Tract Infection Other Serious 11/10/2009 Male 12/30/2009 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious Male 12/30/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 Male 1/6/2010 Pharmacist Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 Male 1/15/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 10/12/2009 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 Male 1/15/2010 Pharmacist Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Face Injury Hospitalization 12/18/2009 Male 1/18/2010 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 1/25/2010 United States
Primary
Concomitant
Platelet Count Increased Other Serious 3/1/2009 Male 185 lb 1/25/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Increased Other Serious 4/5/2008 18 Male 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 10/6/2009 Female 2/25/2010 Physician New Zealand
Primary
Concomitant
Vomiting Other Serious Female 3/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2001 Male 3/19/2010 Physician Australia
Primary
Concomitant
Tachycardia Other Serious 1/1/2008 55 Male 200 lb 4/6/2010 Pharmacist United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 7/15/2008 49 Male 4/6/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/1/2009 60 Male 171 lb 4/8/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/1/2009 60 Male 171 lb 4/21/2010 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/1/2009 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Tobacco User Other Serious 11/1/2009 60 Male 171 lb 5/26/2010 Other Health Professional
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/29/2010 80 Female 194 lb 6/4/2010 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 4/13/2010 69 Female 6/3/2010 Physician Denmark
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 4/9/2010 44 Male 249 lb 8/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis C Other Serious Male 8/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 7/16/2010 23 Female 8/17/2010 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Female 8/23/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2004 42 Female 285 lb 9/3/2010 United States
Primary
Concomitant
Poikilocytosis Hospitalization 8/11/2010 37 Male 9/13/2010 Consumer United Kingdom
Primary
Concomitant
Tooth Abscess Hospitalization 7/24/2010 36 Female 198 lb 9/15/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 5/10/2010 39 Male 187 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/16/2002 34 Male 243 lb 9/17/2010 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2000 41 Female 230 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 53 Male 266 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/1/2005 52 Male 255 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/6/2004 41 Male 181 lb 9/21/2010 United States
Primary
Concomitant
Obesity Other Serious 6/1/2010 45 Female 9/21/2010 Physician United Kingdom
Primary
Concomitant
Lung Cancer Metastatic Death Female 9/23/2010 Other Health Professional Canada
Primary
Concomitant
Tachycardia Other Serious 8/3/2010 41 Male 9/23/2010 Pharmacist United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 5/10/2010 39 Male 187 lb 9/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/11/2010 37 Male 9/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 7/20/2010 60 Female 9/27/2010 Pharmacist United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/25/2004 48 Male 311 lb 9/28/2010 United States
Primary
Concomitant
Acute Myocardial Infarction Other Serious 8/3/2010 56 Female 10/14/2010 Other Health Professional Canada
Primary
Concomitant
Schizoaffective Disorder Other Serious Female 10/19/2010 Consumer United States
Primary
Concomitant
Obesity Other Serious 6/1/2010 45 Female 10/21/2010 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2007 52 Male 10/21/2010 United Kingdom
Primary
Concomitant
Schizoaffective Disorder Other Serious Female 10/22/2010 Physician United States
Primary
Concomitant
Overdose Other Serious Female 10/28/2010 Physician Australia
Primary
Secondary
Concomitant
Tachycardia Other Serious Female 11/26/2010 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious Female 11/29/2010 Physician Australia
Primary
Secondary
Concomitant
Overdose Other Serious 8/22/2010 47 Female 11/29/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 11/30/2010 Other Health Professional Australia
Primary
Concomitant
Pelvic Fracture Hospitalization 10/1/2010 68 Female 12/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/6/2010 52 Female 12/2/2010 Other Health Professional Canada
Primary
Concomitant
Troponin Increased Other Serious 8/28/2009 55 Male 12/9/2010 Pharmacist Australia
Primary
Concomitant
Overdose Other Serious 8/22/2010 47 Female 12/13/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 10/1/2010 68 Female 12/14/2010 Consumer United Kingdom
Primary
Concomitant
Pelvic Fracture Hospitalization 10/1/2010 68 Female 12/22/2010 Consumer United Kingdom
Primary
Concomitant
Wound Infection Other Serious 10/25/2010 39 Female 12/22/2010 Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/21/2010 40 Male 12/21/2010 Pharmacist United Kingdom
Primary
Concomitant
Ankle Fracture Hospitalization 11/20/2010 63 Female 1/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Asthenia Other Serious Female 1/5/2011 Physician United Kingdom
Primary
Concomitant
Hepatitis C Virus Test Positive Hospitalization Male 1/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Other Serious Male 1/24/2011 Physician United Kingdom
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 1/1/2007 52 Male 163 lb 1/27/2011 Pharmacist United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization Male 1/27/2011 Physician United Kingdom
Primary
Concomitant
Hyperhidrosis Other Serious 11/15/2004 42 Female 285 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Intentional Self-injury Other Serious Female 2/24/2011 Physician United Kingdom
Primary
Concomitant
Schizophrenia Other Serious 8/22/2010 47 Female 2/7/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Constipation Other Serious 7/6/1998 47 Male 258 lb 3/2/2011 Other Health Professional United States
Primary
Concomitant
Hyperlipidaemia Other Serious 11/15/2004 42 Female 285 lb 3/10/2011 Consumer United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 11/9/2010 17 Female 199 lb 3/15/2011 Physician United Kingdom
Primary
Concomitant
Aortic Stenosis Death Female 3/22/2011 Physician Canada
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 3/28/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 4/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrioventricular Block Complete Other Serious 31 Female 4/5/2011 Physician United States
Primary
Concomitant
Diabetic Complication Other Serious 11/15/2004 42 Female 285 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Other Serious Male 4/7/2011 Pharmacist United Kingdom
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 31 Female 4/7/2011 Physician United States
Primary
Concomitant
Blood Magnesium Decreased Other Serious 4/15/2010 63 Female 218 lb 4/13/2011 Physician Australia
Primary
Concomitant
Cholecystitis Life Threatening 10/25/2010 39 Female 4/14/2011 Other Health Professional Canada
Primary
Concomitant
Loss Of Consciousness Other Serious 11/24/2010 41 Female 4/20/2011 Physician Australia
Primary
Secondary
Concomitant
Osteoporosis Other Serious 2/22/2011 62 Female 4/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 2/22/2011 62 Female 4/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Large Intestinal Obstruction Death Male 5/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Antipsychotic Drug Level Below Therapeutic Other Serious Male 12/27/2011 Physician United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 7/6/2010 49 Female 3/7/2012 Physician United Kingdom
Primary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 3/14/2012 Other Health Professional United Kingdom
Primary
Concomitant
Dementia Alzheimer's Type Other Serious Female 8/21/2012 Consumer Canada
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/22/2012 49 Male 8/22/2012 Physician Ireland
Primary
Concomitant
Antipsychotic Drug Level Increased Other Serious 2/20/2012 40 Female 8/22/2012 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2010 49 Female 8/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Death 4/19/2012 54 Male 8/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 3/1/2013 Physician Gb
Primary
Concomitant
Schizophrenia Hospitalization 9/14/2012 38 Female 10/9/2012 Other Health Professional Au
Primary
Concomitant
Renal Failure Acute Disability Female 9/3/2012 Physician Ca
Primary
Concomitant
Thrombocytopenia Other Serious 2010 Male 10/26/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/2004 Male 9/12/2012 Other Health Professional Gb
Primary
Concomitant
Toxicity To Various Agents Death 4/19/2012 55 Male 11/30/2012 Physician Gb
Primary
Concomitant
Hypertrophy Other Serious 5/30/2012 37 Male 260 lb 11/13/2012 Physician Au
Primary
Concomitant
Schizophrenia Hospitalization 9/11/2012 29 Male 11/22/2012 Other Health Professional Au
Primary
Concomitant
White Blood Cell Count Decreased 9/1/2012 36 Female 10/18/2012 Physician Gb
Primary
Secondary
Eosinophil Count Increased Other Serious 9/18/2012 38 Male 12/10/2012 Physician Ie
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2012 35 Female 10/8/2012 Physician Gb
Primary
Secondary
Viral Infection Other Serious 9/21/2012 37 Female 11/28/2012 Physician Au
Primary
Concomitant
Toxicity To Various Agents Other Serious 11/28/2011 48 Male 10/15/2012 Physician Au
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/7/2012 29 Female 10/22/2012 Other Health Professional Gb
Primary
Concomitant
Sinus Tachycardia Hospitalization 7/22/2012 31 Male 10/25/2012 Other Health Professional Nz
Primary
Concomitant
Skin Infection Hospitalization 11/17/2011 28 Male 10/29/2012 Pharmacist Au
Primary
Concomitant
Troponin Increased Other Serious 9/10/2012 47 Male 194 lb 11/14/2012 Other Health Professional Au
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/11/2012 61 Female 12/19/2012 Other Health Professional Gb
Primary
Concomitant
Seasonal Allergy Other Serious 2005 66 Female 188 lb 12/28/2012 Us
Primary
Secondary
Concomitant

Drug Data