Clozaril combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 1/1/2002 39 Female 154 lb 1/11/2006 Physician Canada
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/30/2005 78 Male 135 lb 3/10/2006 United States
Primary
Concomitant
Paracentesis Other Serious 2/1/2006 60 Female 5/24/2006 Pharmacist United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 4/3/2006 69 Female 6/12/2006 Physician United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 6/26/2006 44 Male 183 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/6/2006 48 Male 12/14/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/28/2006 44 Male 2/21/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 2/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 351 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/28/2006 28 Female 351 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 5/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/16/2002 40 Female 5/26/2007 Physician Canada
Primary
Secondary
Concomitant
Sudden Death Other Serious 1/4/2006 36 Female 251 lb 7/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 1/4/2006 36 Female 7/5/2007
Primary
Concomitant
Sudden Unexplained Death In Epilepsy Death 1/4/2006 36 Female 7/9/2007 United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 1/4/2006 36 Female 7/11/2007 Other Health Professional United States
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/10/2007 Physician United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 36 Female 251 lb 7/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/30/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 36 Female 7/12/2007 United Kingdom
Primary
Secondary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 8/29/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 2/1/2007 43 Female 9/11/2007 Pharmacist United Kingdom
Primary
Concomitant
Diabetic Coma Other Serious 1/1/2002 47 Female 250 lb 9/18/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 2/1/2007 43 Female 9/29/2007 Pharmacist United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 53 Female 11/21/2007 Pharmacist United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 38 Female 12/14/2007 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Other Serious 39 Male 2/15/2008 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Disorder Other Serious Male 8/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Hypertrophy Other Serious Male 10/28/2008 Other Health Professional Australia
Primary
Concomitant
Paraesthesia Other Serious 9/12/2008 Male 11/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/18/2008 Female 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
Hypothyroidism Other Serious 9/5/2008 Male 1/6/2009 Physician United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 12/16/2008 Female 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash 1/1/2008 45 Female 2/27/2009 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/15/2008 Female 3/6/2009 Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/27/2009 Female 3/19/2009 Other Health Professional Canada
Primary
Concomitant
Pyrexia Other Serious 3/2/2009 Male 4/4/2009 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 3/17/2009 Male 4/8/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/27/2009 Female 4/8/2009 Other Health Professional Canada
Primary
Concomitant
Urinary Incontinence Other Serious 12/15/2008 Female 4/13/2009 Physician Canada
Primary
Concomitant
Weight Increased Other Serious 2/17/2002 Male 306 lb 5/4/2009 Physician United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious Female 5/11/2009 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 4/30/2009 Female 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Salivary Hypersecretion Other Serious Female 7/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 5/28/2009 Female 7/14/2009 Pharmacist United Kingdom
Primary
Concomitant
Therapy Cessation Other Serious Female 7/15/2009 Pharmacist Ireland
Primary
Concomitant
Therapy Cessation Other Serious Female 7/20/2009 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/17/2009 Female 8/6/2009 Other Health Professional New Zealand
Primary
Concomitant
Tardive Dyskinesia Other Serious 11/24/2006 42 Male 243 lb 8/27/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 45 Female 217 lb 9/11/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2009 Male 9/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 51 Female 160 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/21/2004 46 Male 350 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 51 Female 157 lb 9/23/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 8/27/2009 Female 10/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Hospitalization 8/1/2009 Female 10/12/2009 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 6/1/2008 20 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 6/1/2008 20 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2008 20 Female 10/22/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 11/2/2009 United States
Primary
Concomitant
Self Injurious Behaviour Other Serious 6/1/2008 20 Female 10/27/2009
Primary
Secondary
Concomitant
Death Death 9/25/2009 Male 130 lb 11/3/2009 Pharmacist United Kingdom
Primary
Concomitant
Death Death 9/25/2009 Male 130 lb 11/10/2009 Pharmacist United Kingdom
Primary
Concomitant
Weight Increased Other Serious 20 Female 11/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Other Serious 9/21/2009 Male 11/16/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2009 Female 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Bronchopneumonia Death Female 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapy Cessation Other Serious Female 11/19/2009 Pharmacist Ireland
Primary
Concomitant
Dyspnoea Other Serious 1/1/2007 Female 11/19/2009 Physician United Kingdom
Primary
Concomitant
Bronchopneumonia Death Female 11/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Female 11/23/2009 Other Health Professional Australia
Primary
Concomitant
Therapy Cessation Other Serious Female 11/30/2009 Pharmacist Ireland
Primary
Concomitant
Somnolence Other Serious 10/8/2009 Female 12/3/2009 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 12/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/1/2007 Male 130 lb 12/24/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 12/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 213 lb 1/25/2010 United States
Primary
Concomitant
Somnolence Other Serious 10/8/2009 Female 1/25/2010 Other Health Professional Ireland
Primary
Concomitant
Weight Increased Other Serious 2/17/2002 Male 306 lb 1/29/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 Male 1/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thyroxine Increased Other Serious 1/1/2007 Female 2/3/2010 Physician United Kingdom
Primary
Concomitant
Thyroxine Increased Other Serious 1/1/2007 Female 2/19/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 Male 2/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thyroxine Increased Other Serious 1/1/2007 Female 3/9/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2001 Male 3/19/2010 Physician Australia
Primary
Concomitant
Surgery Other Serious 1/1/2010 57 Female 4/13/2010 Physician Ireland
Primary
Concomitant
Mental Impairment Hospitalization Male 4/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 1/23/2010 31 Female 4/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2010 57 Female 5/11/2010 Physician Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 5/19/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/29/2010 80 Female 194 lb 6/4/2010 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 4/14/2010 58 Female 6/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 4/14/2010 58 Female 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypothyroidism Other Serious 6/1/2009 44 Male 7/1/2010 Physician United Kingdom
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 1/1/2008 65 Female 7/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Death 1/1/2008 65 Female 7/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2010 57 Female 7/13/2010 Physician Ireland
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 1/1/2008 65 Female 7/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 4/14/2010 58 Female 7/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious Male 7/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 1/1/2008 0 Female 7/20/2010 Other Health Professional
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Death 1/1/2008 65 Female 7/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 65 Female 7/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 65 Female 7/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2010 57 Female 7/29/2010 Physician Ireland
Primary
Concomitant
Non-small Cell Lung Cancer Other Serious 65 Female 7/24/2010 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 8/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 1/1/2008 65 Female 7/29/2010 Other Health Professional
Primary
Secondary
Concomitant
Wheezing Other Serious 1/9/2004 41 Female 285 lb 8/11/2010 United States
Primary
Concomitant
Completed Suicide Death 7/16/2010 23 Female 8/17/2010 Physician United Kingdom
Primary
Concomitant
Gait Disturbance Hospitalization Female 8/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 65 Female 8/7/2010 United Kingdom
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization Male 8/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious Female 8/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 7/13/2010 74 Female 122 lb 8/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Wheezing Other Serious 3/1/2004 42 Female 285 lb 9/3/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 9/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 7/13/2010 74 Female 122 lb 9/9/2010 Pharmacist United Kingdom
Primary
Concomitant
Surgery Other Serious 1/1/2010 57 Female 9/20/2010 Physician Ireland
Primary
Concomitant
Urinary Tract Infection Other Serious 8/20/2010 65 Male 9/23/2010 Physician United Kingdom
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 7/20/2010 60 Female 9/27/2010 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/1/2010 45 Male 9/29/2010 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 6/22/2010 44 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 6/22/2010 44 Female 10/12/2010 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 10/27/2010 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/25/2010 41 Male 11/2/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 11/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lethargy Hospitalization 8/20/2009 71 Female 11/18/2010 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/30/2010 50 Female 11/18/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 41 Male 11/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Salivary Hypersecretion Other Serious Male 11/26/2010 Physician New Zealand
Primary
Concomitant
Overdose Other Serious 8/22/2010 47 Female 11/29/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/21/2010 55 Female 12/13/2010 Pharmacist United Kingdom
Primary
Concomitant
Malaise Hospitalization 11/25/2010 32 Male 1/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Other Serious Male 2/22/2011 Physician New Zealand
Primary
Concomitant
Hyperhidrosis Other Serious 11/15/2004 42 Female 285 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 10/18/2010 72 Female 2/23/2011 Physician United Kingdom
Primary
Concomitant
Schizophrenia Other Serious 8/22/2010 47 Female 2/7/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/20/2011 62 Male 3/7/2011 Consumer Australia
Primary
Concomitant

Drug Data