Clozaril combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Other Serious 61 Female 1/10/2006 United Kingdom
Primary
Concomitant
Splenomegaly Other Serious 5/13/2005 62 Male 250 lb 2/10/2006 Physician United States
Primary
Concomitant
Heart Rate Irregular Other Serious 6/1/2006 50 Male 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 8/16/2006 Physician United Kingdom
Primary
Secondary
Weight Increased Other Serious 6/1/2006 50 Male 8/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 10/24/2006 Pharmacist United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 11/10/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/1/2007 45 Female 5/11/2007 Pharmacist Ireland
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 5/31/2007 Pharmacist United Kingdom
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 1/25/2007 38 Male 106 lb 7/23/2007 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 65 Female 10/18/2007 United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 53 Female 11/21/2007 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 65 Female 12/13/2007 United Kingdom
Primary
Concomitant
Somnolence Other Serious 9/1/2007 54 Male 12/13/2007 Pharmacist United Kingdom
Primary
Concomitant
Drug Level Increased Death 62 Male 12/25/2007 Other Health Professional United States
Primary
Concomitant
Gastric Disorder Other Serious 1/1/2006 46 Male 198 lb 1/9/2008 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 30 Female 3/11/2008 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2007 54 Male 3/15/2008 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/31/2008 55 Female 4/17/2008 Physician Ireland
Primary
Concomitant
Renal Failure Acute Hospitalization 57 Female 5/13/2008 Consumer Ireland
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 63 Male 5/22/2008 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/22/2008 Male 6/18/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious Female 7/21/2008 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/17/2008 Female 7/28/2008 Consumer Ireland
Primary
Concomitant
Myocardial Infarction Other Serious 7/13/2008 Female 7/29/2008 Other Health Professional Ireland
Primary
Concomitant
Myocardial Infarction Other Serious 7/13/2008 Female 8/1/2008 Other Health Professional Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/10/2007 Male 8/8/2008 Physician
Primary
Concomitant
Myocardial Infarction Death 56 Female 8/26/2008 Consumer Ireland
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 8/27/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious Female 9/16/2008 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 8/31/2008 Male 10/2/2008 Physician United Kingdom
Primary
Concomitant
X-ray Abnormal Hospitalization 6/1/2008 Male 10/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious Female 10/14/2008 United Kingdom
Primary
Concomitant
Ultrasound Scan Abnormal Other Serious 6/24/2008 Male 10/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/29/2007 Male 10/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 7/1/2008 Male 10/31/2008 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 9/3/2008 Male 10/31/2008 Physician United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 9/12/2008 Male 11/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Death 1/1/2008 Male 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
Intentional Self-injury Hospitalization Male 12/2/2008 Physician United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 8/31/2008 Male 12/4/2008 Physician United Kingdom
Primary
Concomitant
Viral Infection Other Serious 11/22/2008 Male 12/22/2008 Physician Ireland
Primary
Concomitant
Tremor Other Serious 11/18/2008 Female 12/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Intentional Self-injury Hospitalization 8/1/2007 Male 12/29/2008 Physician United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious Male 12/31/2008 Physician United Kingdom
Primary
Concomitant
Intentional Self-injury Hospitalization 8/1/2007 Male 1/6/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/20/2008 Male 1/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 12/16/2008 Female 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/2/2008 Male 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 12/16/2008 Female 1/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious Male 2/2/2009 Physician United Kingdom
Primary
Concomitant
Haemolytic Anaemia Other Serious Male 2/4/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/19/2009 Male 2/13/2009 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 11/1/2008 Male 200 lb 2/17/2009 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 10/9/2006 Male 2/23/2009 Pharmacist United Kingdom
Primary
Concomitant
Thoracic Vertebral Fracture Other Serious 11/1/2008 Female 3/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 11/25/2008 Male 205 lb 3/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/27/2009 Female 3/19/2009 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 4/29/2007 Male 4/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/27/2009 Female 4/8/2009 Other Health Professional Canada
Primary
Concomitant
Treatment Noncompliance Other Serious 4/6/2009 Male 386 lb 5/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 Female 6/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/22/2009 Female 6/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/1/2006 36 Female 6/24/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/22/2009 United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 6/6/2008 Male 7/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 6/21/2009 Female 7/20/2009 Physician United Kingdom
Primary
Concomitant
Oropharyngeal Pain Other Serious 6/11/2009 Male 7/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Other Serious 6/21/2009 Female 7/23/2009 Physician United Kingdom
Primary
Concomitant
Completed Suicide Death 5/21/2009 Male 7/24/2009 Physician United Kingdom
Primary
Concomitant
Malaise Hospitalization Female 280 lb 8/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 6/6/2009 Male 8/12/2009 Physician Ireland
Primary
Concomitant
Gastrointestinal Carcinoma Hospitalization Male 8/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious Female 8/25/2009 Physician United Kingdom
Primary
Concomitant
Syncope Life Threatening Male 8/28/2009 Physician Ireland
Primary
Concomitant
Polyneuropathy Other Serious 3/1/2004 46 Male 178 lb 9/4/2009 United States
Primary
Concomitant
Drug Ineffective 7/6/2009 Female 9/16/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/20/2009 Male 9/21/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/20/2009 Male 9/24/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 10/8/2009 Physician United Kingdom
Primary
Concomitant
Lethargy Hospitalization 8/1/2009 Female 10/12/2009 Pharmacist Ireland
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 10/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 4/6/2009 60 Male 386 lb 10/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 12/3/2008 55 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 12/3/2008 55 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 10/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 35 Male 10/26/2009 Physician United Kingdom
Primary
Concomitant
Breast Cancer Stage Ii Other Serious Female 10/27/2009 Physician United Kingdom
Primary
Concomitant
Peptic Ulcer Haemorrhage Other Serious 12/3/2008 55 Male 10/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 11/2/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 47 Male 10/30/2009 United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 12/3/2008 55 Male 11/6/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 35 Female 11/4/2009 United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/12/2006 Female 11/17/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 12/3/2008 55 Male 11/19/2009 United Kingdom
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 12/3/2008 55 Male 11/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 5/12/2006 36 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/12/2006 36 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/10/2009 Male 12/8/2009 Physician United Kingdom
Primary
Concomitant
Peptic Ulcer Other Serious 12/3/2008 55 Male 12/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 12/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Schizophrenia, Catatonic Type Hospitalization 2/1/2008 57 Male 12/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization Male 12/18/2009 Physician United Kingdom
Primary
Concomitant
Schizophrenia, Catatonic Type Other Serious 2/1/2008 57 Male 12/16/2009 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization Female 12/29/2009 Other Health Professional Canada
Primary
Concomitant
H1n1 Influenza Hospitalization Female 12/30/2009 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 11/10/2009 Male 12/30/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/4/2009 Male 12/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/7/2009 Male 12/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Neoplasm Other Serious Male 1/7/2010 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/10/2009 Male 1/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytosis Other Serious 9/1/2007 31 Male 1/20/2010 Other Health Professional Denmark
Primary
Concomitant
Urine Flow Decreased Other Serious 3/1/2008 Male 2/4/2010 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/10/2009 Male 2/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious Female 2/12/2010 Other Health Professional Canada
Primary
Concomitant
Malaise Other Serious 1/1/2008 Male 2/12/2010 Physician United Kingdom
Primary
Concomitant
Repetitive Speech Other Serious 2/1/2008 Female 203 lb 2/15/2010 Physician United Kingdom
Primary
Concomitant
Interacting
Metastatic Neoplasm Other Serious Male 2/16/2010 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/10/2009 23 Male 2/25/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/10/2009 23 Male 3/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/1/2009 23 Male 3/5/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious Female 3/12/2010 Consumer United Kingdom
Primary
Concomitant
Peptic Ulcer Other Serious 12/3/2008 55 Male 3/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/1/2002 Male 3/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Thrombosis Death Male 3/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mastectomy Other Serious Female 4/1/2010 Physician United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Death Male 4/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 1/1/2008 55 Male 200 lb 4/6/2010 Pharmacist United Kingdom
Primary
Concomitant
Rash Other Serious 1/1/2004 31 Male 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/1/2002 31 Male 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 2/18/2010 56 Male 4/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mastectomy Other Serious Female 4/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Repetitive Speech Other Serious 2/1/2008 20 Female 203 lb 4/8/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Repetitive Speech Other Serious 20 Female 4/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious Male 4/21/2010 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/8/2010 32 Female 4/26/2010 Physician United Kingdom
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious Female 280 lb 4/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/25/2009 32 Male 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 1/1/2004 31 Male 4/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Flow Decreased Other Serious 7/1/2008 21 Male 5/5/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2009 61 Male 5/5/2010 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 3/1/2002 31 Male 5/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 4/5/2010 40 Male 5/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/8/2010 32 Female 5/10/2010 Physician United Kingdom
Primary
Concomitant
Interacting

Drug Data