Clozaril combined with Lactulose

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Congestion Other Serious 9/9/2003 53 Male 251 lb 1/16/2006 United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 9/9/2003 53 Male 553 lb 2/13/2006 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 8/1/2005 66 Male 3/21/2006 Physician Australia
Primary
Concomitant
Hypertension Other Serious 8/12/2005 68 Male 3/27/2006 Pharmacist Canada
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/16/2006 60 Female 6/8/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/1/1995 45 Male 7/5/2006 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 8/16/2006 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 10/24/2006 Pharmacist United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/12/2006 36 Female 11/10/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tibia Fracture Other Serious 4/1/2006 52 Male 11/20/2006 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 49 Male 12/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 49 Male 1/4/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastritis Other Serious 2/1/2006 56 Female 11/28/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 1/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Hospitalization 12/8/2006 56 Male 205 lb 1/30/2007 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 2/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 351 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/28/2006 28 Female 351 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Life Threatening 12/1/2006 56 Male 205 lb 4/3/2007 United States
Primary
Concomitant
Red Cell Distribution Width Increased Other Serious 1/1/2001 52 Female 11/6/2006 Physician United States
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 5/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Other Serious 12/1/2006 82 Female 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 57 Female 5/13/2008 Consumer Ireland
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Malaise Other Serious 4/19/2008 Female 6/2/2008 Physician Canada
Primary
Concomitant
Neutropenia Disability 4/1/2008 56 Male 130 lb 5/27/2008 Pharmacist United States
Primary
Concomitant
Thinking Abnormal Other Serious 4/14/2008 Male 6/12/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 5/17/2005 Male 7/22/2008 Other Health Professional Ireland
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/17/2008 Female 7/28/2008 Consumer Ireland
Primary
Concomitant
Drug Level Changed Other Serious 7/23/2008 Male 9/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Other Serious 7/5/2008 Female 10/1/2008 Physician United Kingdom
Primary
Concomitant
X-ray Abnormal Hospitalization 6/1/2008 Male 10/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 6/24/2008 Male 10/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious Female 10/20/2008 Physician New Zealand
Primary
Concomitant
Cardio-respiratory Arrest Death 9/5/2008 Male 10/30/2008 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2008 Male 11/26/2008 Physician United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 2/1/2008 Male 12/15/2008 Pharmacist United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 7/23/2008 Male 12/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Other Serious 8/26/2008 Female 12/30/2008 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/19/2008 Male 12/31/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 11/20/2008 Male 1/7/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/21/2008 Male 1/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Malignant Life Threatening 12/16/2008 Female 2/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/26/2008 Female 2/22/2009 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/19/2008 Male 2/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/15/2009 Male 3/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 2/1/2009 3/20/2009 Physician Taiwan, Province Of China
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/19/2008 Male 4/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 4/9/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 2/1/2004 Female 5/12/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/30/2008 Male 322 lb 5/12/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/30/2008 Male 322 lb 5/14/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Other Serious Female 5/15/2009 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 3/23/2009 Male 6/18/2009 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 4/30/2009 Female 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 Female 6/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/12/2006 36 Female 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/1/2006 36 Female 6/24/2009 United Kingdom
Primary
Secondary
Concomitant
Salivary Hypersecretion Other Serious Male 7/2/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/30/2009 Female 7/23/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/30/2009 Female 8/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Hospitalization 7/25/2009 Male 8/18/2009 Pharmacist United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious Female 8/25/2009 Physician United Kingdom
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 11/1/2008 Female 8/27/2009 Physician United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 4/21/2009 Female 8/28/2009 Physician United Kingdom
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 11/1/2008 Female 9/2/2009 Physician United Kingdom
Primary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious 8/17/2009 Male 9/11/2009 Physician United Kingdom
Primary
Concomitant
Drug Ineffective 7/6/2009 Female 9/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 9/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/2006 28 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 8/10/2009 Male 9/23/2009 Physician Ireland
Primary
Concomitant
Cellulitis Hospitalization 8/6/2009 Male 9/24/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 10/8/2009 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 10/12/2009 Pharmacist United Kingdom
Primary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 10/14/2009 United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 7/23/2008 40 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Regurgitation Death 10/8/2009 Male 10/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 40 Male 10/23/2009 Physician United Kingdom
Primary
Concomitant
Breast Cancer Stage Ii Other Serious Female 10/27/2009 Physician United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Other Serious 7/23/2008 40 Male 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Other Serious 1/28/2009 Male 10/29/2009 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 11/2/2009 Physician United Kingdom
Primary
Concomitant
Death Death 9/25/2009 Male 130 lb 11/3/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2006 36 Female 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 35 Female 11/4/2009 United Kingdom
Primary
Secondary
Platelet Count Increased Other Serious 12/16/2008 Female 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 9/25/2009 Male 130 lb 11/10/2009 Pharmacist United Kingdom
Primary
Concomitant
Nasopharyngitis Other Serious 55 Male 205 lb 11/11/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/12/2006 Female 11/17/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 5/12/2006 36 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Tube Insertion Hospitalization 2/11/2009 Female 11/24/2009 Pharmacist United Kingdom
Primary
Concomitant
Unevaluable Event Other Serious 7/12/2006 36 Female 11/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/13/2009 Male 12/2/2009 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 8/10/2009 Male 12/9/2009 Physician Ireland
Primary
Concomitant
Neutrophil Count Increased Death 11/17/2009 Male 12/14/2009 Consumer New Zealand
Primary
Concomitant
Haemoglobin Decreased Hospitalization Male 12/18/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/1/2007 Male 130 lb 12/24/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2008 Male 1/6/2010 Physician United Kingdom
Primary
Concomitant
Metastatic Neoplasm Other Serious Male 1/7/2010 Physician United Kingdom
Primary
Concomitant
Constipation Other Serious 11/1/2009 Male 2/2/2010 Consumer United Kingdom
Primary
Concomitant
Pericarditis Hospitalization Male 2/2/2010 Physician Ireland
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization Male 2/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 Male 2/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Peritonitis Other Serious Male 2/4/2010 Physician Ireland
Primary
Concomitant
Urine Flow Decreased Other Serious 3/1/2008 Male 2/4/2010 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2008 Male 2/12/2010 Physician United Kingdom
Primary
Concomitant
Metastatic Neoplasm Other Serious Male 2/16/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 Male 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Constipation Other Serious Male 2/25/2010 Consumer United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/1/2009 Male 3/2/2010 Other Health Professional New Zealand
Primary
Concomitant
Vomiting Other Serious 1/18/2010 Male 3/2/2010 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 Female 3/2/2010 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious Female 3/3/2010 Physician New Zealand
Primary
Concomitant
Ventricular Extrasystoles Other Serious 10/22/2009 Male 3/8/2010 Other Health Professional New Zealand
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 Male 3/12/2010 Pharmacist United Kingdom
Primary
Concomitant
Tremor Other Serious Female 3/12/2010 Physician New Zealand
Primary
Concomitant
Peritonitis Other Serious 1/1/2010 Male 3/22/2010 Physician Ireland
Primary
Concomitant
Sudden Death Death 2/19/2010 Male 3/22/2010 Physician United Kingdom
Primary
Concomitant
Skin Injury Other Serious 10/8/2009 Male 3/23/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 Male 3/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mastectomy Other Serious Female 4/1/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/18/2010 58 Male 4/12/2010 Physician United Kingdom
Primary
Concomitant
Mastectomy Other Serious Female 4/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 45 Male 4/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Scar Other Serious 10/8/2009 36 Male 4/8/2010 Physician Denmark
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 45 Male 4/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 56 Male 4/20/2010 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 1/24/2010 56 Male 4/21/2010 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 45 Male 5/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urine Flow Decreased Other Serious 7/1/2008 21 Male 5/5/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2009 61 Male 5/5/2010 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Hospitalization Male 5/6/2010 Physician United Kingdom
Primary
Concomitant
Salivary Gland Cancer Other Serious 2/1/2010 55 Male 5/12/2010 Other Health Professional Canada
Primary
Concomitant
Obstruction Life Threatening 1/3/2010 71 Male 5/17/2010 Pharmacist United Kingdom
Primary
Concomitant
Salivary Gland Cancer Other Serious 2/1/2010 55 Male 5/25/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 6/2/2010 Physician Ireland
Primary
Concomitant
Regurgitation Other Serious 10/8/2009 44 Male 121 lb 6/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 6/30/2010 Other Health Professional Ireland
Primary
Concomitant
Pulmonary Oedema Other Serious Male 7/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Obstruction Life Threatening 1/3/2010 71 Male 7/6/2010 Pharmacist United Kingdom
Primary
Concomitant
Tachycardia Other Serious 2/28/2010 45 Female 7/9/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 5/1/2010 56 Male 7/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 2/28/2010 45 Female 7/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Flow Decreased Other Serious 7/1/2008 21 Male 8/12/2010 Physician United Kingdom
Primary
Concomitant

Drug Data