Clozaril combined with Hyoscine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Other Serious 1/1/2006 25 Male 9/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 8/9/2007 47 Male 10/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 27 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 9/1/2007 54 Male 12/13/2007 Pharmacist United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 27 Male 12/28/2007 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 6/1/2007 27 Male 1/11/2008 Consumer United Kingdom
Primary
Secondary
Tachycardia Other Serious 11/23/2007 37 Male 1/16/2008 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 6/1/2007 1/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Tachycardia Other Serious 11/23/2007 37 Male 1/26/2008 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2007 54 Male 3/15/2008 Pharmacist United Kingdom
Primary
Concomitant
Tachycardia Other Serious 1/1/2006 27 Male 4/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/21/2008 45 Male 4/18/2008 Physician Australia
Primary
Concomitant
White Blood Cell Disorder Other Serious 1/1/2008 45 Male 4/26/2008 Physician Australia
Primary
Concomitant
Multiple Drug Overdose Intentional 37 Male 4/27/2008 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Disorder Other Serious 1/1/2008 45 Male 5/1/2008 Physician Australia
Primary
Concomitant
Intentional Overdose Other Serious 37 Male 5/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 24 Female 5/20/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/1/2006 24 Female 5/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/5/2008 Male 5/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/5/2008 Male 6/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/5/2008 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 24 Female 6/10/2008
Primary
Secondary
Concomitant
Vomiting Other Serious 4/5/2008 6/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 5/17/2005 Male 7/22/2008 Other Health Professional Ireland
Primary
Secondary
Concomitant
Underweight Other Serious 4/1/2008 Male 7/31/2008 United Kingdom
Primary
Concomitant
Tachycardia Other Serious Male 9/5/2008 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/20/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious Male 10/14/2008 Ireland
Primary
Concomitant
Tachycardia Other Serious 9/22/2008 Male 10/20/2008 Pharmacist Ireland
Primary
Concomitant
Neutropenia Other Serious Male 11/18/2008 Ireland
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/18/2008 Female 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Death 1/1/2008 Male 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2008 Male 11/26/2008 Physician United Kingdom
Primary
Concomitant
Fall Hospitalization 10/3/2008 Male 12/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious Male 1/21/2009 Pharmacist Ireland
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 2/6/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 2/14/2009 Physician United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/4/2008 Male 2/17/2009 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 10/9/2006 Male 2/23/2009 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 2/26/2009 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2009 Male 3/3/2009 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization 2/17/2009 Male 3/4/2009 Pharmacist United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 1/21/2009 Male 3/9/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/21/2009 Male 3/17/2009 Physician United Kingdom
Primary
Concomitant
Overdose Hospitalization 39 Male 3/16/2009 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 3/23/2009 Male 4/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious Male 5/4/2009 Pharmacist United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Life Threatening 4/18/2009 Male 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2008 Female 5/11/2009 Physician United Kingdom
Primary
Concomitant
Overdose Other Serious 2/17/2009 Male 5/13/2009 Pharmacist United Kingdom
Primary
Secondary
Overdose Other Serious 2/17/2009 Male 5/25/2009 Pharmacist United Kingdom
Primary
Secondary
Salivary Hypersecretion Other Serious Male 5/26/2009 Pharmacist United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Life Threatening 4/18/2009 42 Male 5/21/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/1/2009 Pharmacist United Kingdom
Primary
Concomitant
Petechiae Other Serious 4/27/2009 Male 194 lb 6/3/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 6/29/2009 Pharmacist United Kingdom
Primary
Concomitant
Salivary Hypersecretion Other Serious Male 7/2/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization Male 7/27/2009 Pharmacist United Kingdom
Primary
Concomitant
Completed Suicide Death 7/2/2009 Female 7/30/2009 Other Health Professional Ireland
Primary
Concomitant
Malaise Hospitalization Female 280 lb 8/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Speech Disorder Other Serious 6/12/2009 Male 156 lb 8/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious Male 8/14/2009 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious Male 8/14/2009 Pharmacist Ireland
Primary
Concomitant
Malaise Hospitalization 7/25/2009 Male 8/18/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/23/2009 Male 8/21/2009 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Other Serious Male 8/24/2009 Pharmacist Ireland
Primary
Concomitant
Withdrawal Syndrome Other Serious Male 8/31/2009 Pharmacist Ireland
Primary
Concomitant
Weight Increased Other Serious 3/1/2009 Female 9/4/2009 Pharmacist United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious Male 9/10/2009 Pharmacist Ireland
Primary
Concomitant
Tongue Biting Death 5/28/2003 Female 203 lb 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/20/2009 Male 9/21/2009 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious Male 9/22/2009 Pharmacist Ireland
Primary
Concomitant
Syncope Other Serious 8/10/2009 Male 9/23/2009 Physician Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/21/2009 Male 9/24/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/20/2009 Male 9/24/2009 Physician United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious Male 9/25/2009 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/21/2009 Male 10/14/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 8/10/2009 Female 10/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/20/2007 44 Female 10/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/26/2009 Pharmacist Germany
Primary
Secondary
Vomiting Hospitalization 7/20/2008 35 Male 10/26/2009 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Life Threatening 4/18/2009 42 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Life Threatening 4/18/2009 42 Male 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/22/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 2/17/2009 39 Male 10/27/2009 Pharmacist
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/30/2009 Male 11/4/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 10/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 11/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 Pharmacist Germany
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/16/2009 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/10/2009 United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Life Threatening 4/18/2009 Male 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/28/2009 Female 252 lb 11/19/2009 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/30/2009 Male 11/20/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/1/2009 Pharmacist Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/28/2009 Female 252 lb 12/2/2009 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 8/10/2009 Male 12/9/2009 Physician Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 24 Female 12/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/15/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 24 Female 12/15/2009 United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 5/1/2006 24 Female 12/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 12/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 23 Female 12/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 23 Female 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/2/2009 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/29/2009 Pharmacist Germany
Primary
Secondary
White Blood Cell Count Increased Life Threatening 2/17/2009 39 Male 12/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Abuse Hospitalization Male 12/30/2009 Other Health Professional Australia
Primary
Concomitant
Weight Decreased Life Threatening 5/2/2006 23 Female 12/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 23 Female 12/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 12/30/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/2/2006 23 Female 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/23/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/1/2008 Male 1/6/2010 Physician United Kingdom
Primary
Concomitant
Pyrexia Other Serious 10/2/2009 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 12/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Life Threatening 5/2/2006 23 Female 1/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious Female 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious Female 1/14/2010 Physician United Kingdom
Primary
Concomitant
Tongue Coated Other Serious 1/12/2008 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 1/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 18 Male 2/2/2010 United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/1/2009 Female 2/19/2010 Pharmacist Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/17/2009 39 Male 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 11/30/2005 Male 238 lb 3/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious Male 3/12/2010 Pharmacist Ireland
Primary
Concomitant
Nervousness Other Serious 3/2/2010 Female 3/22/2010 Physician United Kingdom
Primary
Concomitant
Ventricular Dysfunction Other Serious Male 3/23/2010 Physician United Kingdom
Primary
Concomitant

Drug Data