Clozaril combined with Hyoscine Hydrobromide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Intentional Overdose Hospitalization 10/8/2010 24 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 10/8/2010 24 Male 3/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Disorder Other Serious 8/1/2006 40 Male 4/26/2011 Physician United Kingdom
Primary
Concomitant
Dizziness Hospitalization Male 4/7/2011 Physician United Kingdom
Primary
Concomitant
Urine Colour Abnormal Other Serious Male 5/3/2011 Physician United Kingdom
Primary
Concomitant
Blood Calcium Decreased Other Serious 1/1/2004 37 Male 5/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/26/2011 44 Male 5/13/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/1/2011 47 Female 5/16/2011 Physician United Kingdom
Primary
Concomitant
Blood Alkaline Phosphatase Increased Death 8/1/2006 40 Male 5/17/2011 Physician United Kingdom
Primary
Concomitant
Blood Urine Present Other Serious 2/2/2011 43 Male 5/24/2011 Physician United Kingdom
Primary
Concomitant
Renal Mass Hospitalization 2/22/2011 72 Male 5/25/2011 Physician United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 4/28/2011 47 Female 261 lb 6/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 5/21/2011 44 Male 7/1/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/21/2011 44 Male 7/27/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Hepatitis Hospitalization 6/25/2011 43 Female 315 lb 10/18/2011 Pharmacist United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 8/8/2011 31 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hiatus Hernia Hospitalization 9/6/2011 45 Female 10/24/2011 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 10/6/2010 52 Female 10/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 9/17/2011 36 Male 10/25/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 9/19/2011 62 Male 180 lb 10/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/12/2011 44 Male 164 lb 10/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 10/31/2011 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 5/12/2011 44 Male 164 lb 11/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/12/2011 44 Male 164 lb 11/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ideas Of Reference Other Serious 5/12/2011 44 Male 164 lb 11/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Microcytic Anaemia Other Serious 5/21/2011 44 Male 11/2/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Stridor Other Serious 11/1/2008 38 Female 11/11/2011 Physician United Kingdom
Primary
Concomitant
Nasopharyngitis Other Serious 12/20/2010 25 Male 11/11/2011 Physician United Kingdom
Primary
Concomitant
Anaemia Hospitalization 9/19/2011 62 Male 180 lb 11/11/2011 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 6/15/2011 22 Male 11/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 10/20/2011 57 Female 11/23/2011 Physician United Kingdom
Primary
Concomitant
Oedema Hospitalization 9/6/2011 45 Female 11/29/2011 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Increased Hospitalization 10/1/2011 24 Male 12/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Death 7/3/2011 40 Male 12/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Increased Death 11/14/2011 64 Male 12/5/2011 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 11/9/2010 17 Female 199 lb 12/6/2011 Physician United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Death Male 12/26/2011 Pharmacist United Kingdom
Primary
Concomitant
Lethargy Other Serious 11/29/2011 32 Male 1/4/2012 Physician United Kingdom
Primary
Concomitant
Large Intestinal Obstruction Death 3/13/2006 48 Female 152 lb 1/9/2012 Physician United Kingdom
Primary
Concomitant
Foaming At Mouth Other Serious 1/1/2005 46 Female 152 lb 1/11/2012 Physician United Kingdom
Primary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 1/11/2012 Physician United Kingdom
Primary
Concomitant
Overweight Hospitalization 7/29/2011 56 Male 1/12/2012 Physician United Kingdom
Primary
Concomitant
Blood Urea Increased Disability 10/12/2011 59 Female 157 lb 1/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 9/1/2011 74 Male 1/16/2012 Physician United Kingdom
Primary
Concomitant
Excoriation Other Serious 1/1/2005 46 Female 152 lb 1/17/2012 Physician United Kingdom
Primary
Concomitant
Nodule Other Serious 1/1/2005 46 Female 152 lb 1/19/2012 Consumer United Kingdom
Primary
Concomitant
Fatigue Other Serious 11/29/2011 32 Male 1/20/2012 Physician United Kingdom
Primary
Concomitant
Diabetes Mellitus Hospitalization 7/29/2011 56 Male 1/24/2012 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Increased Other Serious 2/1/2011 47 Female 1/27/2012 Physician United Kingdom
Primary
Concomitant
Anaemia Disability 10/12/2011 59 Female 157 lb 1/27/2012 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 9/17/2011 36 Male 2/1/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death Male 150 lb 2/2/2012 Physician United Kingdom
Primary
Concomitant
Blood Alkaline Phosphatase Increased Disability 10/12/2011 59 Female 157 lb 2/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 5/21/2011 44 Male 164 lb 2/7/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/4/2012 70 Male 163 lb 2/8/2012 Physician United Kingdom
Primary
Concomitant
Electrocardiogram T Wave Abnormal Hospitalization 1/26/2012 50 Female 2/21/2012 Pharmacist Australia
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 1/4/2012 70 Male 163 lb 2/21/2012 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 4/6/2011 58 Female 2/23/2012 Consumer United Kingdom
Primary
Concomitant
Infection Other Serious 10/12/2011 59 Female 157 lb 2/28/2012 Physician United Kingdom
Primary
Concomitant
Schizophrenia Other Serious 10/6/2010 52 Female 2/28/2012 Physician United Kingdom
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 1/4/2012 70 Male 163 lb 3/1/2012 Physician United Kingdom
Primary
Concomitant
Heart Rate Increased Other Serious 11/29/2011 32 Male 3/5/2012 Physician United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 7/6/2010 49 Female 3/7/2012 Physician United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 10/6/2010 52 Female 3/11/2012 Other Health Professional United Kingdom
Primary
Concomitant
Lymphocyte Count Increased Other Serious 7/6/2010 49 Female 3/14/2012 Other Health Professional United Kingdom
Primary
Concomitant
Antipsychotic Drug Level Increased Other Serious 11/29/2011 32 Male 3/19/2012 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 10/6/2010 52 Female 3/26/2012 Physician United Kingdom
Primary
Concomitant
Thinking Abnormal Other Serious 12/3/2011 25 Male 3/27/2012 Physician United Kingdom
Primary
Concomitant
Fatigue Disability 4/6/2011 58 Female 3/27/2012 Physician United Kingdom
Primary
Concomitant
Death Death Male 3/27/2012 Physician United Kingdom
Primary
Concomitant
Fatigue Other Serious 4/6/2011 58 Female 4/1/2012 Consumer United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/31/2009 31 Male 4/2/2012 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2010 49 Female 4/10/2012 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 1/1/2012 30 Male 4/12/2012 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 10/6/2010 52 Female 4/13/2012 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 10/14/2011 37 Male 4/16/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 10/12/2011 59 Female 157 lb 4/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Other Serious 10/14/2011 37 Male 4/26/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 10/14/2011 37 Male 4/30/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious Female 5/2/2012 Physician United Kingdom
Primary
Concomitant
Appendicitis Hospitalization 9/10/2011 40 Male 5/7/2012 Physician United Kingdom
Primary
Concomitant
Schizophrenia Other Serious 3/6/2012 34 Male 5/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2010 49 Female 5/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Mean Cell Volume Decreased Other Serious 4/3/2012 16 Female 187 lb 5/8/2012 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 9/5/2011 48 Female 5/10/2012 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2007 23 Male 186 lb 5/15/2012 Physician United Kingdom
Primary
Concomitant
Uterine Leiomyoma Other Serious 9/5/2011 48 Female 5/15/2012 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2010 49 Female 5/16/2012 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 3/5/2012 62 Male 5/21/2012 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 5/9/2012 20 Male 5/28/2012 Pharmacist United Kingdom
Primary
Concomitant
Sinus Tachycardia Other Serious 2/8/2012 62 Male 5/31/2012 Pharmacist Ireland
Primary
Concomitant
Haemoglobin Decreased Death 4/19/2012 54 Male 6/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Fall Other Serious 2/8/2012 62 Male 6/4/2012 Physician Ireland
Primary
Concomitant
Haemoglobin Decreased Other Serious 9/5/2011 48 Female 6/8/2012 Physician United Kingdom
Primary
Concomitant
Menorrhagia Other Serious 9/5/2011 48 Female 6/13/2012 Other Health Professional United Kingdom
Primary
Concomitant
Heart Rate Increased Other Serious 11/29/2011 32 Male 6/22/2012 Physician United Kingdom
Primary
Concomitant
Myocardial Bridging Death Male 174 lb 6/28/2012 Physician United Kingdom
Primary
Concomitant
Syncope Other Serious 2/8/2012 62 Male 6/29/2012 Physician Ireland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2010 49 Female 7/2/2012 Physician United Kingdom
Primary
Concomitant
Haematemesis Other Serious 11/29/2011 32 Male 7/4/2012 Physician United Kingdom
Primary
Concomitant
Bone Pain Other Serious 10/31/2009 31 Male 7/6/2012 Physician United Kingdom
Primary
Concomitant
Sedation Hospitalization Male 156 lb 7/8/2012 Physician United Kingdom
Primary
Concomitant
Osteomyelitis Hospitalization 10/12/2011 59 Female 157 lb 7/9/2012 Physician United Kingdom
Primary
Concomitant
Serum Ferritin Increased Life Threatening 10/12/2011 59 Female 157 lb 7/11/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Increased Other Serious 10/31/2009 31 Male 7/12/2012 Physician United Kingdom
Primary
Concomitant
Splenomegaly Other Serious 10/31/2009 31 Male 7/12/2012 Physician United Kingdom
Primary
Concomitant
Colitis Death Male 156 lb 7/13/2012 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Death Male 7/23/2012 Physician United Kingdom
Primary
Concomitant
Metabolic Syndrome Hospitalization 9/9/2002 36 Male 215 lb 7/24/2012 Physician United Kingdom
Primary
Concomitant
Cardiac Disorder Other Serious 2/8/2012 62 Male 8/1/2012 Pharmacist Ireland
Primary
Concomitant
Completed Suicide Death 6/12/2012 25 Male 8/2/2012 Physician United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/31/2009 31 Male 8/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 4/13/2012 53 Male 8/6/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Other Serious 5/29/2012 58 Male 161 lb 8/8/2012 Physician United Kingdom
Primary
Concomitant
Anxiety Other Serious 36 Female 8/9/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Antipsychotic Drug Level Below Therapeutic Other Serious 12/18/2011 23 Male 228 lb 8/10/2012 Physician United Kingdom
Primary
Concomitant
Head Injury Death Male 212 lb 8/10/2012 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious Female 8/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Responder Other Serious Female 8/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 2/8/2012 62 Male 8/22/2012 Physician Ireland
Primary
Concomitant
Mental Impairment Other Serious 5/29/2012 58 Male 161 lb 8/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/6/2010 49 Female 8/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Death 4/19/2012 54 Male 8/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 36 Female 8/24/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Irregular Hospitalization 12/18/2011 23 Male 228 lb 8/24/2012 Physician United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious 9/19/2011 62 Male 180 lb 8/27/2012 Other Health Professional United Kingdom
Primary
Concomitant
Anxiety Other Serious Female 8/27/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Anxiety Other Serious Female 8/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 9/19/2011 62 Male 180 lb 9/3/2012 Other Health Professional Gb
Primary
Concomitant
Urosepsis Hospitalization 9/9/2002 37 Male 215 lb 9/3/2012 Other Health Professional Gb
Primary
Concomitant
Heart Disease Congenital Death Male 12/24/2012 Physician Gb
Primary
Concomitant
Schizophrenia Other Serious 3/6/2012 34 Male 10/24/2012 Other Health Professional Gb
Primary
Concomitant
Syncope Hospitalization 2/8/2012 62 Male 12/8/2012 Pharmacist Ie
Primary
Concomitant
Rhabdomyolysis Other Serious 4/13/2012 54 Male 10/23/2012 Other Health Professional Gb
Primary
Concomitant
Toxicity To Various Agents Death 4/19/2012 55 Male 11/30/2012 Physician Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/16/2012 41 Male 10/18/2012 Physician Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/28/2012 46 Female 10/5/2012 Physician Gb
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 6/28/2012 46 Female 10/23/2012 Physician Gb
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 7/2012 Male 11/10/2012 Pharmacist Gb
Primary
Concomitant
Therapy Responder Other Serious 36 Female 9/21/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Therapy Responder Other Serious 36 Female 9/21/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Wrist Fracture Life Threatening 8/13/2012 44 Male 158 lb 10/5/2012 Physician Gb
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization Male 10/30/2012 Physician Gb
Primary
Concomitant
Haematemesis Other Serious Male 11/6/2012 Physician Gb
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/17/2012 28 Male 235 lb 9/28/2012 Other Health Professional Gb
Primary
Concomitant
Weight Decreased Other Serious Male 10/9/2012 Other Health Professional Gb
Primary
Concomitant
Thinking Abnormal Hospitalization Male 9/20/2012 Other Health Professional Gb
Primary
Concomitant
Platelet Count Decreased Other Serious 8/13/2012 40 Female 9/24/2012 Other Health Professional Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/28/2012 57 Male 11/27/2012 Other Health Professional Gb
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/28/2012 46 Female 10/23/2012 Other Health Professional Gb
Primary
Secondary
Concomitant

Drug Data