Clozaril combined with Depakote

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypertrophy Other Serious 8/12/2001 75 Female 170 lb 12/29/2005 Lawyer United States
Primary
Concomitant
Tachypnoea Life Threatening 1/1/2003 36 Female 243 lb 1/6/2006 United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/28/2005 41 Male 1/18/2006 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious 9/9/2003 53 Male 251 lb 1/16/2006 United States
Primary
Secondary
Concomitant
Terminal State Life Threatening 1/1/2004 57 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/28/2005 41 Male 182 lb 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 9/9/2003 53 Male 553 lb 2/13/2006 Physician United States
Primary
Secondary
Concomitant
Rash 8/13/2005 44 Male 2/28/2006 Consumer United States
Primary
Concomitant
Aspiration Death 10/10/2003 19 Male 3/8/2006 Physician United States
Primary
Concomitant
Aspiration Death 10/10/2003 20 Male 3/13/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2000 41 Female 155 lb 3/2/2006 Lawyer United States
Primary
Concomitant
Terminal State Life Threatening 8/1/2003 57 Male 3/28/2006 Other Health Professional United States
Primary
Concomitant
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 12/18/1998 26 Male 243 lb 4/1/2006 Lawyer United States
Primary
Concomitant
Paracentesis Other Serious 2/1/2006 60 Female 5/24/2006 Pharmacist United States
Primary
Concomitant
Hallucination Other Serious 26 Female 7/28/2006 Physician United States
Primary
Secondary
Weight Increased Other Serious 1/1/2006 19 Male 145 lb 8/3/2006 United States
Primary
Concomitant
Rash Erythematous Hospitalization 6/26/2006 44 Male 183 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 19 Male 145 lb 8/3/2006 United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2005 44 Male 8/2/2006 Physician United States
Primary
Concomitant
Prescribed Overdose Other Serious 1/1/1999 54 Male 214 lb 9/13/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/1/2005 35 Male 10/30/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/6/2006 48 Male 12/14/2006 Physician United Kingdom
Primary
Concomitant
Pneumonia Aspiration Other Serious 11/18/2006 32 Female 12/16/2006 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 49 Male 12/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 49 Male 1/4/2007 United Kingdom
Primary
Concomitant
Enuresis 31 Female 12/29/2006 Physician United States
Primary
Concomitant
Hyperglycaemia Hospitalization 1/1/2002 34 Female 191 lb 1/16/2007 Consumer United States
Primary
Concomitant
Vertigo Other Serious 42 Male 1/23/2007 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 42 Male 2/8/2007 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 8/1/2006 42 Male 370 lb 2/20/2007 United States
Primary
Concomitant
Sinusitis Other Serious 8/1/2006 42 Male 370 lb 2/20/2007 United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/4/2007 32 Male 183 lb 2/24/2007 Physician United Kingdom
Primary
Concomitant
Sinusitis Other Serious 8/1/2006 42 Male 370 lb 2/20/2007 United States
Primary
Concomitant
Renal Failure Hospitalization 10/1/2001 54 Female 280 lb 3/10/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/7/2007 32 Male 183 lb 3/10/2007 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 3/25/2007 Physician United States
Primary
Secondary
Hyperglycaemia Hospitalization 1/1/2002 34 Female 191 lb 3/27/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/4/1996 28 Female 11/6/2006 Physician United States
Primary
Concomitant
Myocarditis Hospitalization 10/11/2005 20 Female 243 lb 11/6/2006 Physician United States
Primary
Concomitant
Dyskinesia Hospitalization 53 Female 11/6/2006 Other Health Professional United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 6/13/2006 19 Male 11/6/2006 Physician United States
Primary
Concomitant
Red Blood Cell Count Increased Death 6/6/2006 37 Female 11/6/2006 Physician United States
Primary
Concomitant
Thrombocythaemia Other Serious 1/1/1995 44 Male 200 lb 11/6/2006 Physician United States
Primary
Secondary
Malaise Hospitalization 4/9/2006 53 Male 11/6/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Death 8/4/2006 53 Male 178 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Overdose Other Serious 1/1/1999 43 Male 90 lb 4/5/2007 Physician United States
Primary
Concomitant
Road Traffic Accident Death 1/18/2007 41 Male 4/11/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 8/1/2002 21 Male 4/18/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 19 Female 4/19/2007 Physician United Kingdom
Primary
Concomitant
Death Hospitalization 4/15/2007 61 4/19/2007 United States
Primary
Concomitant
Death Hospitalization 4/15/2007 61 4/21/2007 United States
Primary
Concomitant
Tachycardia Other Serious 4/12/2007 19 Female 4/23/2007 Physician United Kingdom
Primary
Concomitant
Vertigo Other Serious 42 Male 5/23/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 64 Female 6/12/2007 Pharmacist United States
Primary
Concomitant
Skin Disorder Hospitalization Male 335 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Metabolic Disorder Other Serious 1/1/1997 42 Male 195 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 2/1/2003 47 Male 261 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Sinusitis Other Serious 8/1/2006 42 Male 370 lb 7/23/2007 United States
Primary
Concomitant
Sinusitis Other Serious 8/1/2006 42 Male 370 lb 7/23/2007 United States
Primary
Concomitant
Vision Blurred Other Serious 6/5/2007 51 Male 8/14/2007 Physician United Kingdom
Primary
Concomitant
Platelet Count Increased Other Serious 7/9/2007 50 Male 320 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 37 Female 245 lb 9/10/2007 Consumer United States
Primary
Concomitant
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 9/13/2007 Physician United Kingdom
Primary
Concomitant
Diabetic Ketoacidosis Other Serious Male 318 lb 9/18/2007 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 246 lb 9/18/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 53 Female 140 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/1/2003 47 Male 261 lb 10/26/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 10/17/2007 79 Female 11/2/2007 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 1/1/2005 47 Female 224 lb 11/2/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 10/17/2007 59 Female 11/15/2007 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 11/7/2007 57 Female 11/24/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/1996 Female 318 lb 10/9/2007 Consumer United States
Primary
Concomitant
Metabolic Disorder Other Serious 5/1/2003 39 Female 192 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Pain In Extremity Other Serious 38 Female 12/14/2007 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 1/1/2000 42 Female 224 lb 1/3/2008 Other Health Professional United States
Primary
Concomitant
Recurrent Cancer Hospitalization 10/14/2004 26 Female 1/4/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2005 Female 250 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 6/1/2002 59 Female 186 lb 2/12/2008 Other Health Professional United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 6/1/2002 59 Female 186 lb 2/12/2008 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/1999 54 Female 2/18/2008 Consumer United States
Primary
Secondary
Neutropenia Other Serious 2/19/2008 Male 2/26/2008 Physician United States
Primary
Concomitant
Excessive Eye Blinking Other Serious 12/1/2007 45 Male 249 lb 3/5/2008 United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2002 47 Female 250 lb 3/27/2008 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2002 47 Female 250 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2002 47 Female 250 lb 4/8/2008 Other Health Professional United States
Primary
Concomitant
Ketoacidosis Hospitalization 24 Male 4/24/2008 Physician United States
Primary
Concomitant
Tremor Other Serious 6/3/1999 41 Female 224 lb 5/1/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/1999 45 Male 299 lb 6/23/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/20/2008 Male 6/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death Male 7/4/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 8/1/2006 24 Male 580 lb 7/7/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 7/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 8/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Diabetes Mellitus Hospitalization 12/1/2004 49 Male 215 lb 9/24/2008 Physician United States
Primary
Concomitant
Schizophrenia Hospitalization 1/1/2001 24 Female 220 lb 9/24/2008 Physician United States
Primary
Concomitant
Blood Glucose Increased Male 227 lb 10/20/2008 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/5/2008 22 Female 221 lb 11/4/2008 Pharmacist United States
Primary
Concomitant
Wound Dehiscence Other Serious 12/1/2001 41 Male 294 lb 11/17/2008 United States
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/18/2008 Female 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/25/2008 Female 12/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/25/2008 Female 12/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 10/5/2008 Female 225 lb 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 47 Female 1/12/2009 Physician
Primary
Concomitant
Tachypnoea Other Serious 47 Female 1/9/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/25/2008 Female 2/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Viral Other Serious 5/1/2003 Male 2/9/2009 Other Health Professional United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 14 Male 2/12/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization Female 2/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 8/11/1998 48 Female 263 lb 4/9/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2003 Male 4/13/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2005 40 Male 305 lb 4/17/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 4/23/2001 35 Female 232 lb 4/17/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 4/23/2009 Consumer United States
Primary
Secondary
Renal Failure Hospitalization 12/1/2008 Female 5/1/2009 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 47 Male 5/5/2009 Consumer United States
Primary
Concomitant
Schizophrenia Hospitalization 1/1/2001 42 Female 187 lb 5/20/2009 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 12/1/2001 41 Male 290 lb 5/20/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/1998 33 Male 231 lb 6/3/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 53 Female 179 lb 6/8/2009 United States
Primary
Concomitant
Neutropenia 11/1/2007 Male 6/16/2009 Physician United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 6/1/1999 37 Male 207 lb 6/25/2009 United States
Primary
Concomitant
Vomiting Other Serious 6/8/2009 Female 7/6/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization Male 7/8/2009 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Presyncope 6/20/2009 Female 7/9/2009 Consumer
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2006 28 Female 218 lb 7/13/2009 United States
Primary
Concomitant
Renal Failure Other Serious 10/1/2001 53 Female 270 lb 7/15/2009 United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 140 lb 7/16/2009 United States
Primary
Concomitant
Weight Increased Other Serious 9/1/1999 45 Male 240 lb 7/17/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 6/1/2006 34 Female 193 lb 7/17/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/4/2000 42 Female 217 lb 7/21/2009 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/1/2002 83 Female 130 lb 7/22/2009 United States
Primary
Concomitant
Surgery Other Serious 6/21/2009 Female 7/23/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased 4/28/1999 Female 250 lb 7/24/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 5/15/2009 Male 7/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 33 Female 238 lb 7/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1998 41 Male 303 lb 7/30/2009 United States
Primary
Concomitant
Speech Disorder Other Serious 4/1/2009 Male 147 lb 8/5/2009 Physician United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1998 31 Male 246 lb 8/6/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2006 54 Female 149 lb 8/6/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/4/1998 49 Female 158 lb 8/11/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2002 47 Female 248 lb 8/12/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 28 Male 236 lb 8/24/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2003 35 Female 134 lb 8/28/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/13/2002 47 Male 215 lb 8/31/2009 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/17/2009 51 Male 8/27/2009 Pharmacist United States
Primary
Concomitant

Drug Data