Clozapine combined with Zyprexa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased 18 Male 1/11/2006 Physician United Kingdom
Primary
Concomitant
Neutropenia 10/26/2005 18 Male 1/31/2006 United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 1/12/2006 76 Male 2/14/2006 Physician Netherlands
Primary
Concomitant
Thinking Abnormal Other Serious 1/1/2002 60 Female 2/6/2006 Physician Switzerland
Primary
Concomitant
White Blood Cell Count Decreased 12/1/2005 17 Male 2/20/2006 United Kingdom
Primary
Concomitant
Tooth Disorder Hospitalization 1/21/2006 36 Male 3/9/2006 Physician Finland
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 4/3/2005 51 Female 4/21/2005 Other Health Professional United States
Primary
Concomitant
Mania Hospitalization 2/1/2002 55 Male 5/10/2005 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 10/27/2004 48 Female 12/2/2004 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 1/1/2004 26 Male 12/30/2004 Physician United States
Primary
Secondary
Neutropenia Required Intervention 2/15/2005 55 Female 186 lb 4/11/2005 Pharmacist United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 2/8/2005 15 Male 3/7/2005 Pharmacist United States
Primary
Secondary
Laboratory Test Abnormal Hospitalization 7/1/2004 50 Female 11/29/2004 Pharmacist United States
Primary
Concomitant
Muscle Contractions Involuntary Other Serious 12/25/2005 30 Male 163 lb 4/21/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Neutropenia 4/7/2006 20 Female 4/16/2006 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 60 Female 5/24/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tremor Other Serious 7/1/2003 60 Female 6/2/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2005 37 Female 188 lb 5/25/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/9/2006 39 Male 5/24/2006 Physician New Zealand
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/25/2006 34 Male 5/25/2006 United Kingdom
Primary
Concomitant
Granulocytopenia 50 Female 6/29/2006 Physician United States
Primary
Concomitant
Death Death 6/27/2006 77 Female 7/13/2006 United States
Primary
Concomitant
Weight Increased Required Intervention 8/31/2005 41 Female 1/11/2006 United States
Primary
Secondary
Concomitant
Intentional Overdose Death 3/1/2006 32 Female 8/11/2006 Physician France
Primary
Concomitant
Treatment Noncompliance Hospitalization 6/27/2006 77 Female 8/30/2006 Consumer United States
Primary
Concomitant
Blood Count Abnormal Other Serious Male 9/11/2006 United Kingdom
Primary
Concomitant
Death Death 8/4/2006 71 Male 9/27/2006 United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 7/26/2006 32 Male 10/11/2006 Other Health Professional Switzerland
Primary
Concomitant
Rhabdomyolysis Other Serious Male 10/16/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Death 3/1/2006 33 Female 170 lb 10/10/2006 Physician France
Primary
Concomitant
Premature Baby Other Serious 10/4/2005 0 Female 10/19/2006 Physician Germany
Primary
Concomitant
Treatment Noncompliance Death 3/1/2006 33 Female 170 lb 10/12/2006 Physician France
Primary
Concomitant
Pancreatitis Other Serious 1/1/1997 28 Male 302 lb 10/26/2006 Lawyer United States
Primary
Concomitant
Prescribed Overdose Hospitalization 29 Male 11/30/2006 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 10/1/2003 45 Male 210 lb 12/13/2006 Consumer United States
Primary
Concomitant
Prescribed Overdose Hospitalization 11/1/2006 29 Male 1/5/2007 Physician United Kingdom
Primary
Concomitant
Myocardial Ischaemia Hospitalization 10/1/1999 47 Female 238 lb 1/8/2007 Consumer United States
Primary
Concomitant
Polyuria Other Serious 1/1/1997 35 Female 190 lb 1/10/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 11/29/2006 Male 282 lb 1/19/2007 Pharmacist United States
Primary
Secondary
Weight Increased Hospitalization 1/1/2004 47 Female 312 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2002 Female 121 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Obesity Hospitalization 1/1/2002 44 Male 199 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 3/1/2003 42 Male 301 lb 1/25/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 48 Male 136 lb 2/3/2007 Consumer United States
Primary
Concomitant
Urine Cannabinoids Increased Death Male 204 lb 2/16/2007 Germany
Primary
Concomitant
Electrocution Death 11/13/2006 61 Male 2/14/2007 Physician Hungary
Primary
Concomitant
Extrapyramidal Disorder Other Serious 1/1/2005 37 Female 2/28/2007 Consumer Germany
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/11/2007 56 Male 190 lb 2/27/2007 Pharmacist United States
Primary
Concomitant
Diabetic Coma Other Serious Female 3/11/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Male 3/12/2007 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Male 3/12/2007 Physician Canada
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 71 Female 3/20/2007 Physician Italy
Primary
Concomitant
Neuroleptic Malignant Syndrome Death 45 Male 3/28/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 11/26/2006 59 Male 4/3/2007 Consumer Finland
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 3/13/2007 23 Male 4/14/2007 Physician Denmark
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 4/1/2006 30 Male 4/21/2007 Physician Finland
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 1/1/2004 30 Male 5/23/2007 Physician
Primary
Concomitant
Overdose Other Serious 10/12/2006 51 Male 5/23/2007 Physician Switzerland
Primary
Concomitant
Prescribed Overdose Hospitalization 1/1/2003 38 Male 250 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2003 54 Female 196 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Metabolic Disorder Other Serious 1/1/2003 54 Male 248 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Obesity Hospitalization 1/1/2003 24 Female 267 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 12/1/2001 22 Female 130 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Metabolic Disorder Hospitalization 1/1/2005 40 Male 220 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2000 28 Male 253 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 43 Male 250 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2001 37 Male 154 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 50 Female 249 lb 4/2/2007 Consumer United States
Primary
Concomitant
Obesity Other Serious 1/1/2004 35 Female 210 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Pericarditis Hospitalization 5/3/2007 17 Male 6/25/2007 Physician Norway
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 1/1/2005 51 Male 7/4/2007 Physician Switzerland
Primary
Concomitant
Sinusitis Required Intervention 5/16/2007 42 Female 196 lb 8/3/2007 United States
Primary
Concomitant
Drug Toxicity Death 5/18/2006 40 Male 10/16/2007 Physician Denmark
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2006 Male 246 lb 11/1/2007 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 5/1/2007 17 Male 166 lb 11/12/2007 Pharmacist United States
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 1/1/2003 31 Male 227 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Hyperglycaemia Other Serious 8/1/2001 33 Female 156 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Pancreatitis Other Serious 12/1/1998 31 Male 180 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/2005 44 Male 270 lb 10/9/2007 Lawyer United States
Primary
Concomitant
Immune System Disorder Hospitalization 5/1/2007 17 Male 166 lb 12/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 5/1/2007 17 Male 166 lb 12/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Medication Error Other Serious 19 Male 2/6/2008 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 1/1/2004 Male 2/9/2008 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 2/5/2008 Female 2/22/2008 Physician Norway
Primary
Concomitant
Rash Generalised Other Serious 20 Male 3/9/2008 Consumer
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2000 15 Male 4/7/2008 Consumer United States
Primary
Secondary
Concomitant
Myocarditis Death 4/23/2007 Male 408 lb 4/5/2008 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 20 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/1/2008 46 Male 5/5/2008 Physician Belgium
Primary
Secondary
Concomitant
Diabetes Mellitus Female 332 lb 5/27/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 40 Female 6/1/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Psychomotor Retardation Other Serious 8/10/2007 Male 6/24/2008 Germany
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 8/10/2007 54 Male 6/18/2008 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/17/2002 Male 181 lb 7/1/2008 Physician France
Primary
Secondary
Concomitant
Overdose Hospitalization 6/6/2007 Male 148 lb 7/3/2008 Physician Germany
Primary
Concomitant
Pericarditis Hospitalization 7/2/2008 Female 210 lb 7/15/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/29/2008 Norway
Primary
Concomitant
Urinary Tract Infection Other Serious 1/17/2007 45 Male 7/29/2008 Physician United Kingdom
Primary
Concomitant
Thrombosis Other Serious 1/1/2006 36 Male 8/18/2008 Other Health Professional Finland
Primary
Concomitant
Suicide Attempt Other Serious 10/1/2007 Male 8/19/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Overdose Death 6/12/2008 Female 8/27/2008 Physician United States
Primary
Concomitant
Renal Failure Other Serious 22 Male 9/16/2008 Physician Canada
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 9/11/2008 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1996 Female 160 lb 9/24/2008 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 10/2/2008 Physician United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/13/2005 55 Female 10/17/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Overdose Death 6/12/2008 Female 11/3/2008 Physician United States
Primary
Concomitant
Urine Flow Decreased Other Serious 7/1/2008 25 Male 159 lb 12/5/2008 Physician Russian Federation
Primary
Concomitant
Overweight Other Serious 1/1/2003 28 Male 1/22/2009 Consumer Germany
Primary
Concomitant
Overdose Hospitalization 1/1/2003 Male 1/21/2009 Consumer Germany
Primary
Concomitant
Granulocytopenia Other Serious 10/14/2008 Male 2/11/2009 Consumer United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/14/2008 53 Male 2/16/2009 Physician United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Hospitalization 2/1/2003 Female 2/19/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 12/1/2005 Male 245 lb 2/22/2009 Consumer United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 36 Female 3/30/2009 Physician Korea, Republic Of
Primary
Concomitant
Tachycardia Hospitalization 5/16/2009 Male 5/21/2009 Physician United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2006 51 Male 6/4/2009 Physician Sweden
Primary
Concomitant
Renal Failure Other Serious 4/9/2003 52 Male 147 lb 6/19/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 35 Male 183 lb 6/24/2009 United States
Primary
Concomitant
Drug Level Increased Death 8/28/2008 Female 6/17/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 7/1/2009 United States
Primary
Secondary
Concomitant
Overdose Other Serious 12/15/2006 Male 142 lb 7/6/2009 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 42 Female 320 lb 7/28/2009 United States
Primary
Concomitant
Sedation Hospitalization 6/4/2009 69 Male 7/24/2009 Canada
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 10/14/2008 53 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/4/2006 59 Male 348 lb 7/31/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 3/25/2003 45 Female 370 lb 8/3/2009 United States
Primary
Concomitant
Salivary Hypersecretion Other Serious 1/1/2009 Male 170 lb 8/10/2009 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious Female 9/30/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2004 Male 9/28/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Female 210 lb 10/5/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 42 Female 320 lb 10/16/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2004 Male 10/21/2009 Physician United States
Primary
Concomitant
Sedation Hospitalization 6/4/2009 69 Male 10/16/2009 Canada
Primary
Secondary
Concomitant
Respiratory Arrest Death 6/7/2008 Female 161 lb 11/24/2009 Other Health Professional United States
Primary
Secondary
Overdose Hospitalization 6/6/2007 Male 148 lb 12/1/2009 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 12/1/2005 Male 245 lb 12/1/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Female 12/18/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/28/2009 40 Male 192 lb 1/15/2010 Physician France
Primary
Concomitant
Granulocytopenia Other Serious Male 1/12/2010 Physician United States
Primary
Concomitant
Overdose 5/1/2009 Female 104 lb 2/4/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Female 2/17/2010 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 41 Male 4/19/2010 Physician Japan
Primary
Concomitant
Nightmare Hospitalization 2/1/2010 52 Male 4/23/2010 United States
Primary
Concomitant
Restlessness Other Serious 9/28/2009 44 Female 5/17/2010 Physician Switzerland
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 1/1/2010 16 Male 5/21/2010 Physician Mexico
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 1/1/2010 16 Male 5/25/2010 Physician Mexico
Primary
Concomitant
Granulocytopenia Other Serious 24 Male 6/24/2010 Other Health Professional United States
Primary
Concomitant

Drug Data